Alison K Bauer

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Susceptibility to neoplastic and non-neoplastic pulmonary diseases in mice: genetic similarities
    Alison K Bauer
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Am J Physiol Lung Cell Mol Physiol 287:L685-703. 2004
  2. ncbi Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis
    Alison K Bauer
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    J Natl Cancer Inst 97:1778-81. 2005
  3. ncbi Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1
    Alison K Bauer
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Cancer Res 63:929-35. 2003
  4. ncbi Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity
    Alison K Bauer
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 72:201-9. 2003
  5. ncbi Variations in Prkdc and susceptibility to benzene-induced toxicity in mice
    Brenda Faiola
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 75:321-32. 2003
  6. ncbi Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice
    Hye Youn Cho
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Drive, Building 101, MD D 201, Research Triangle Park, NC 27709, USA
    Am J Respir Crit Care Med 175:829-39. 2007
  7. ncbi Protective role of interleukin-10 in ozone-induced pulmonary inflammation
    Gillian S Backus
    National Institute of Environmental Health Sciences, Laboratory of Respiratory Biology, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 118:1721-7. 2010
  8. ncbi Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines
    Lori D Dwyer-Nield
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Carcinogenesis 26:1196-206. 2005
  9. ncbi Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, University of Colorado Health Sciences Center, Denver 80262, USA
    Cancer Res 62:6850-6. 2002
  10. ncbi Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, Denver CO 80262, USA
    Carcinogenesis 23:1653-60. 2002

Collaborators

Detail Information

Publications12

  1. ncbi Susceptibility to neoplastic and non-neoplastic pulmonary diseases in mice: genetic similarities
    Alison K Bauer
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Am J Physiol Lung Cell Mol Physiol 287:L685-703. 2004
    ..These QTLs are described herein, candidate genes are suggested within these sites, and experimental evidence that inflammation enhances lung tumor development is provided...
  2. ncbi Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis
    Alison K Bauer
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    J Natl Cancer Inst 97:1778-81. 2005
    ..To our knowledge, this is the first model to demonstrate a modulatory role for Tlr4 in chronic lung inflammation and tumorigenesis...
  3. ncbi Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1
    Alison K Bauer
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Cancer Res 63:929-35. 2003
    ..These results indicate that NQO1 deficiency results in substantially greater benzene-induced toxicity. However, the specific patterns of toxicity differed between the male and female mice...
  4. ncbi Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity
    Alison K Bauer
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 72:201-9. 2003
    ..Thus mEH appears to be critical in benzene-induced toxicity in male, but not female, mice...
  5. ncbi Variations in Prkdc and susceptibility to benzene-induced toxicity in mice
    Brenda Faiola
    CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 75:321-32. 2003
    ..Prkdc does not appear to be a significant genetic susceptibility factor for acute benzene toxicity. Moreover, the role of NHEJ, mediated by DNA-PK, in restoring genomic integrity following benzene-induced DSB remains equivocal...
  6. ncbi Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice
    Hye Youn Cho
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Drive, Building 101, MD D 201, Research Triangle Park, NC 27709, USA
    Am J Respir Crit Care Med 175:829-39. 2007
    ..We previously determined that mice genetically deficient in TNF response are protected from lung inflammation and epithelial injury after O(3) exposure...
  7. ncbi Protective role of interleukin-10 in ozone-induced pulmonary inflammation
    Gillian S Backus
    National Institute of Environmental Health Sciences, Laboratory of Respiratory Biology, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 118:1721-7. 2010
    ..The mechanisms underlying ozone (O₃)-induced pulmonary inflammation remain unclear. Interleukin-10 (IL-10) is an anti-inflammatory cytokine that is known to inhibit inflammatory mediators...
  8. ncbi Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines
    Lori D Dwyer-Nield
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Carcinogenesis 26:1196-206. 2005
    ....
  9. ncbi Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, University of Colorado Health Sciences Center, Denver 80262, USA
    Cancer Res 62:6850-6. 2002
    ..The substantial (80%) reduction in lung tumor multiplicity in iNOS (-/-) mice strongly supports examining iNOS-specific inhibitors as potential lung cancer chemopreventive agents...
  10. ncbi Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, Denver CO 80262, USA
    Carcinogenesis 23:1653-60. 2002
    ..As the production of eicosanoids in addition to PGE2 is also inhibited by celecoxib, and as celecoxib has COX-independent interactions, its effects on tumor formation may vary in different organ systems...
  11. ncbi Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II
    Morten Dahl
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Clin Invest 117:757-64. 2007
    ..These data identify what we believe to be a novel function for AM SRAs in decreasing pulmonary inflammation after oxidant inhalation by scavenging proinflammatory oxidized lipids from lung lining fluids...
  12. ncbi Quantitative trait locus mapping of susceptibilities to butylated hydroxytoluene-induced lung tumor promotion and pulmonary inflammation in CXB mice
    Alvin M Malkinson
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Carcinogenesis 23:411-7. 2002
    ..The fact that common chromosomal locations regulate both inflammation and carcinogenesis suggests a pathogenic role of inflammatory mediators in tumor development that may be exploited for chemoprevention of lung cancer...