Genomes and Genes
M A Basrai
Affiliation: National Institutes of Health
- NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiaeM A Basrai
Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Mol Cell Biol 19:7041-9. 1999..HUG1 is the first example of a NORF with important biological functional properties and defines a novel component of the MEC1 checkpoint pathway...
- Exploiting the complete yeast genome sequenceD E Bassett
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2185, USA
Curr Opin Genet Dev 6:763-6. 1996....
- Characterization of the yeast transcriptomeV E Velculescu
Program in Human Genetics and Molecular Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
Cell 88:243-51. 1997..These studies provide insight into global patterns of gene expression in yeast and demonstrate the feasibility of genome-wide expression studies in eukaryotes...
- Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiaeM A Basrai
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Mol Cell Biol 16:2838-47. 1996..The results of in vivo genetic interactions with mutations in kinetochore proteins and CEN DNA and of in vitro biochemical assays suggest that Spt4p is important for kinetochore function...
- Characterization of the CHD family of proteinsT Woodage
Laboratory of Gene Transfer, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 94:11472-7. 1997....
- Cloning of a Candida albicans peptide transport geneM A Basrai
Department of Microbiology, University of Tennessee, Knoxville 37996 0845, USA
Microbiology 141:1147-56. 1995..cerevisiae and Arabidopsis thaliana. This study represents the first steps in the genetic characterization of peptide transport in C. albicans and initiates a molecular approach for the study of drug delivery against this pathogen...
- Isolation and characterization of a Saccharomyces cerevisiae peptide transport geneJ R Perry
Department of Microbiology, University of Tennessee, Knoxville 37996
Mol Cell Biol 14:104-15. 1994..The cloning of PTR2 represents the first example of the molecular genetic characterization of a eucaryotic peptide transport gene...
- Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiaeG A Hartzog
Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
Mol Cell Biol 16:2848-56. 1996..Thus, like other proteins that are components of or control the structure of chromatin, Spt4p appears to be conserved from S. cerevisiae to mammals...
- Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregationO Kerscher
Department of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20889, USA
Genetics 157:1543-53. 2001..Our data suggest that NUP170 encodes a specialized nucleoporin with a unique role in chromosome segregation and possibly kinetochore function...