Artem Barski

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Genomic location analysis by ChIP-Seq
    Artem Barski
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA
    J Cell Biochem 107:11-8. 2009
  2. pmc Genomic profiling of HMGN1 reveals an association with chromatin at regulatory regions
    Suresh Cuddapah
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Cell Biol 31:700-9. 2011
  3. pmc Combinatorial patterns of histone acetylations and methylations in the human genome
    Zhibin Wang
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Genet 40:897-903. 2008
  4. pmc Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
    Zhibin Wang
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cell 138:1019-31. 2009
  5. doi request reprint Dynamic regulation of nucleosome positioning in the human genome
    Dustin E Schones
    Laboratory of Molecular Immunology, The National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA
    Cell 132:887-98. 2008
  6. pmc Chromatin poises miRNA- and protein-coding genes for expression
    Artem Barski
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genome Res 19:1742-51. 2009
  7. pmc Pol II and its associated epigenetic marks are present at Pol III-transcribed noncoding RNA genes
    Artem Barski
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nat Struct Mol Biol 17:629-34. 2010
  8. pmc Native chromatin preparation and illumina/solexa library construction
    Suresh Cuddapah
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    CSH Protoc 2009:pdb.prot5237. 2009
  9. pmc Genome-wide identification of in vivo protein-DNA binding sites from ChIP-Seq data
    Raja Jothi
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 36:5221-31. 2008
  10. pmc Epigenomics of T cell activation, differentiation, and memory
    Suresh Cuddapah
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Opin Immunol 22:341-7. 2010

Detail Information

Publications11

  1. pmc Genomic location analysis by ChIP-Seq
    Artem Barski
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA
    J Cell Biochem 107:11-8. 2009
    ..Now protein binding can be mapped in a truly genome-wide manner with extremely high resolution. This review discusses ChIP-Seq technology, its possible pitfalls, data analysis and several early applications...
  2. pmc Genomic profiling of HMGN1 reveals an association with chromatin at regulatory regions
    Suresh Cuddapah
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Cell Biol 31:700-9. 2011
    ..Our results suggest that HMGN1 is part of the cellular machinery that modulates transcriptional fidelity by generating, maintaining, or preferentially interacting with specific sites in chromatin...
  3. pmc Combinatorial patterns of histone acetylations and methylations in the human genome
    Zhibin Wang
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Genet 40:897-903. 2008
    ..Our data suggest that these histone modifications may act cooperatively to prepare chromatin for transcriptional activation...
  4. pmc Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
    Zhibin Wang
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cell 138:1019-31. 2009
    ..Silent genes without any H3K4 methylation signal show no evidence of being bound by HDACs...
  5. doi request reprint Dynamic regulation of nucleosome positioning in the human genome
    Dustin E Schones
    Laboratory of Molecular Immunology, The National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA
    Cell 132:887-98. 2008
    ..Our results suggest that H2A.Z-containing and modified nucleosomes are preferentially lost from the -1 nucleosome position. Our data provide a comprehensive view of the nucleosome landscape and its dynamic regulation in the human genome...
  6. pmc Chromatin poises miRNA- and protein-coding genes for expression
    Artem Barski
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genome Res 19:1742-51. 2009
    ..Our data suggest that miRNA- and protein-coding genes share similar mechanisms of regulation by chromatin modifications, which poise inducible genes for activation in response to environmental stimuli...
  7. pmc Pol II and its associated epigenetic marks are present at Pol III-transcribed noncoding RNA genes
    Artem Barski
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nat Struct Mol Biol 17:629-34. 2010
    ..Our analysis also uncovered an entirely unexpected phenomenon: namely, that Pol II is present at the majority of genomic loci that are bound by Pol III...
  8. pmc Native chromatin preparation and illumina/solexa library construction
    Suresh Cuddapah
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    CSH Protoc 2009:pdb.prot5237. 2009
    ....
  9. pmc Genome-wide identification of in vivo protein-DNA binding sites from ChIP-Seq data
    Raja Jothi
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 36:5221-31. 2008
    ..Using tag density as an indicator of DNA-binding affinity, we have identified core residues within the NRSF and CTCF binding sites that are critical for a stronger DNA binding...
  10. pmc Epigenomics of T cell activation, differentiation, and memory
    Suresh Cuddapah
    Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Opin Immunol 22:341-7. 2010
    ..On the other hand, memory T cells are poised and do not require epigenetic changes for short-term activation...
  11. ncbi request reprint High-resolution profiling of histone methylations in the human genome
    Artem Barski
    Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA
    Cell 129:823-37. 2007
    ..Our data provide new insights into the function of histone methylation and chromatin organization in genome function...