Nader Ayub

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Dendrimer-induced leukocyte procoagulant activity depends on particle size and surface charge
    Marina A Dobrovolskaia
    Nanotechnology Characterization Lab SAIC Frederick Inc, NCI Frederick 1050 Boyles St, Bldg 469 Frederick, MD 21702, USA
    Nanomedicine (Lond) 7:245-56. 2012
  2. pmc Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick Inc, NCI Frederick, Frederick, MD 21702, USA
    Mol Pharm 5:487-95. 2008
  3. pmc Method for analysis of nanoparticle hemolytic properties in vitro
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick Inc, NCI Frederick, Frederick, Maryland 21702, USA
    Nano Lett 8:2180-7. 2008
  4. doi request reprint Immunological properties of engineered nanomaterials
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, NCI Frederick, 1050 Boyles St, Bldg 469, Frederick, Maryland 21702, USA
    Nat Nanotechnol 2:469-78. 2007
  5. pmc Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick Inc, NCI Frederick, Frederick, Maryland 21702, USA
    Nanomedicine 5:106-17. 2009
  6. doi request reprint Evaluation of nanoparticle immunotoxicity
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, SAIC Frederick Inc, NCI Frederick, Frederick, Maryland 21702, USA
    Nat Nanotechnol 4:411-4. 2009
  7. pmc Ambiguities in applying traditional Limulus amebocyte lysate tests to quantify endotoxin in nanoparticle formulations
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, SAIC Frederick Inc, NCI Frederick, Frederick, MD 21702, USA
    Nanomedicine (Lond) 5:555-62. 2010

Collaborators

Detail Information

Publications7

  1. doi request reprint Dendrimer-induced leukocyte procoagulant activity depends on particle size and surface charge
    Marina A Dobrovolskaia
    Nanotechnology Characterization Lab SAIC Frederick Inc, NCI Frederick 1050 Boyles St, Bldg 469 Frederick, MD 21702, USA
    Nanomedicine (Lond) 7:245-56. 2012
    ..The purpose of this study was to investigate the effects of nanoparticle physicochemical properties on leukocyte PCA, and to get insight into the mechanism of PCA induction...
  2. pmc Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick Inc, NCI Frederick, Frederick, MD 21702, USA
    Mol Pharm 5:487-95. 2008
    ..We will also provide an overview of in vitro methods useful in identifying interactions with components of the immune system and the potential effects of such interaction on particle distribution to tissues...
  3. pmc Method for analysis of nanoparticle hemolytic properties in vitro
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick Inc, NCI Frederick, Frederick, Maryland 21702, USA
    Nano Lett 8:2180-7. 2008
    ..We propose alternative methods to avoid misleading results from nanoparticles and discuss the potential relevance of nanoparticle in vitro hemolytic properties to in vivo systems...
  4. doi request reprint Immunological properties of engineered nanomaterials
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, NCI Frederick, 1050 Boyles St, Bldg 469, Frederick, Maryland 21702, USA
    Nat Nanotechnol 2:469-78. 2007
    ..Modifying these factors can significantly reduce the immunotoxicity of nanoparticles and make them useful platforms for drug delivery...
  5. pmc Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick Inc, NCI Frederick, Frederick, Maryland 21702, USA
    Nanomedicine 5:106-17. 2009
    ..The difference in size measurements obtained from dynamic light scattering, electron microscopy, and scanning probe microscopy are also discussed...
  6. doi request reprint Evaluation of nanoparticle immunotoxicity
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, SAIC Frederick Inc, NCI Frederick, Frederick, Maryland 21702, USA
    Nat Nanotechnol 4:411-4. 2009
    ..This article outlines practical strategies for identifying and controlling interferences in common evaluation methods and the implications for regulation...
  7. pmc Ambiguities in applying traditional Limulus amebocyte lysate tests to quantify endotoxin in nanoparticle formulations
    Marina A Dobrovolskaia
    Nanotechnology Characterization Laboratory, SAIC Frederick Inc, NCI Frederick, Frederick, MD 21702, USA
    Nanomedicine (Lond) 5:555-62. 2010
    ..Here we report that nanoparticles often interfere with these traditional endotoxin detection tests and suggest approaches to detect and overcome such interferences...