J C Atkinson

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Salivary hypofunction and xerostomia: diagnosis and treatment
    Jane C Atkinson
    Comprehensive Care and Therapeutics, University of Maryland Dental School, 666 West Baltimore Street, 3E 32, Baltimore, MD 21201 1586, USA
    Dent Clin North Am 49:309-26. 2005
  2. ncbi Oral and dental phenotype of dyskeratosis congenita
    J C Atkinson
    Clinical Research Core, National Institute of Dental and Craniofacial Research, Department of Health and Human Services, National Institutes of Health, Bethesda, MD 20892 6401, USA
    Oral Dis 14:419-27. 2008
  3. ncbi Salivary enhancement: current status and future therapies
    J C Atkinson
    Department of Oral Medicine, University of Maryland Dental School, Baltimore, MD, USA
    J Dent Educ 65:1096-101. 2001
  4. ncbi Salivary gland delivery of pDNA-cationic lipoplexes elicits systemic immune responses
    V Sankar
    Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research NIDCR, NIH, Bethesda, MD 20892, USA
    Oral Dis 8:275-81. 2002
  5. ncbi Chronic graft versus host disease of oral mucosa: review of available therapies
    Matin M Imanguli
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:175-83. 2006
  6. ncbi Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction
    Bruce J Baum
    Gene Therapy and Therapeutics Branch, Bethesda, MD 20892 1190, USA
    Biochim Biophys Acta 1758:1071-7. 2006
  7. ncbi Salivary gland involvement in chronic graft-versus-host disease: prevalence, clinical significance, and recommendations for evaluation
    Matin M Imanguli
    Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Biol Blood Marrow Transplant 16:1362-9. 2010
  8. ncbi Randomized, double-blind, placebo-controlled phase IIb trial of the cyclooxygenase inhibitor ketorolac as an oral rinse in oropharyngeal leukoplakia
    James L Mulshine
    Intervention Section, Cell and Cancer Biology Branch, Department of Pathology and Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892 1906, USA
    Clin Cancer Res 10:1565-73. 2004
  9. ncbi Polarized secretion of transgene products from salivary glands in vivo
    B J Baum
    Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892, USA
    Hum Gene Ther 10:2789-97. 1999
  10. ncbi Oral manifestations in patients with aplastic anemia
    M T Brennan
    Clinical Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:503-8. 2001

Detail Information

Publications17

  1. ncbi Salivary hypofunction and xerostomia: diagnosis and treatment
    Jane C Atkinson
    Comprehensive Care and Therapeutics, University of Maryland Dental School, 666 West Baltimore Street, 3E 32, Baltimore, MD 21201 1586, USA
    Dent Clin North Am 49:309-26. 2005
    ..The systemic agents pilocarpine and cevimeline may help selected patients. Selective use of fluoride-releasing restorative materials and conservative treatment plans are recommended for this patient group...
  2. ncbi Oral and dental phenotype of dyskeratosis congenita
    J C Atkinson
    Clinical Research Core, National Institute of Dental and Craniofacial Research, Department of Health and Human Services, National Institutes of Health, Bethesda, MD 20892 6401, USA
    Oral Dis 14:419-27. 2008
    ..Multiple permanent teeth with decreased root/crown ratios further suggest DC...
  3. ncbi Salivary enhancement: current status and future therapies
    J C Atkinson
    Department of Oral Medicine, University of Maryland Dental School, Baltimore, MD, USA
    J Dent Educ 65:1096-101. 2001
    ..However, these medications do not benefit all patients. The possibilities of using gene therapy and tissue engineering to develop treatments for those with severe salivary dysfunction are discussed...
  4. ncbi Salivary gland delivery of pDNA-cationic lipoplexes elicits systemic immune responses
    V Sankar
    Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research NIDCR, NIH, Bethesda, MD 20892, USA
    Oral Dis 8:275-81. 2002
    ..To test the ability of two cationic lipoplexes, Vaxfectin and GAP-DLRIE/DOPE, to facilitate transfection and elicit immune responses from plasmid DNAs (pDNAs) after retrograde instillation into salivary glands...
  5. ncbi Chronic graft versus host disease of oral mucosa: review of available therapies
    Matin M Imanguli
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:175-83. 2006
    ..Available evidence for efficacy and safety of various systemic and topical agents, including corticosteroids, calcineurin antagonists, mycophenolate mofetil, and extracorporeal photopheresis, is reviewed...
  6. ncbi Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction
    Bruce J Baum
    Gene Therapy and Therapeutics Branch, Bethesda, MD 20892 1190, USA
    Biochim Biophys Acta 1758:1071-7. 2006
    ..Based on these results, we are developing a clinical trial to test if the hAQP1 cDNA transfer strategy will be clinically effective in restoring salivary flow in patients with IR-induced parotid hypofunction...
  7. ncbi Salivary gland involvement in chronic graft-versus-host disease: prevalence, clinical significance, and recommendations for evaluation
    Matin M Imanguli
    Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Biol Blood Marrow Transplant 16:1362-9. 2010
    ..Formal evaluation of salivary function using standardized criteria is needed, and this could be incorporated as an outcome measure in clinical trials of cGVHD...
  8. ncbi Randomized, double-blind, placebo-controlled phase IIb trial of the cyclooxygenase inhibitor ketorolac as an oral rinse in oropharyngeal leukoplakia
    James L Mulshine
    Intervention Section, Cell and Cancer Biology Branch, Department of Pathology and Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892 1906, USA
    Clin Cancer Res 10:1565-73. 2004
    ..This trial evaluated if a topically delivered oral rinse containing ketorolac was as safe as and more effective than oral rinse alone in reducing the area of oral leukoplakia...
  9. ncbi Polarized secretion of transgene products from salivary glands in vivo
    B J Baum
    Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892, USA
    Hum Gene Ther 10:2789-97. 1999
    ..e., in an endocrine manner. The aggregate results are consistent with the recognition of signals encoded within the transgenes that result in specific patterns of polarized protein secretion from rat submandibular gland cells in vivo...
  10. ncbi Oral manifestations in patients with aplastic anemia
    M T Brennan
    Clinical Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:503-8. 2001
    ..The aim of the present study was to characterize the prevalence and risks of oral complications in aplastic anemia (AA)...
  11. ncbi Identification of parotid salivary biomarkers in Sjogren's syndrome by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry and two-dimensional difference gel electrophoresis
    O H Ryu
    Human Craniofacial Genetics Section, Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research (NIDCR, National Institutes of Health (NIH, Bethesda, MD 20892-1470, USA
    Rheumatology (Oxford) 45:1077-86. 2006
    ..Future studies will test the ability of these biomarker levels, alone and in combination, to diagnose the salivary component of SS...
  12. ncbi Oral graft-versus-host disease
    M M Imanguli
    Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
    Oral Dis 14:396-412. 2008
    ..This review describes the oral component of this transplant complication...
  13. ncbi Changes in salivary proteome following allogeneic hematopoietic stem cell transplantation
    Matin M Imanguli
    Clinical Research Core, National Institutes of Health, Bethesda, MD 20892, USA
    Exp Hematol 35:184-92. 2007
    ..This study was an initial evaluation of salivary protein changes that occur after allo-HCT...
  14. ncbi Analyses of variable panoramic radiographic characteristics of maxillo-mandibular fibrous dysplasia in McCune-Albright syndrome
    S O Akintoye
    Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research National Institutes of Health, Bethesda, MD, USA
    Oral Dis 10:36-43. 2004
    ....
  15. ncbi Risk factors for positive minor salivary gland biopsy findings in Sjögren's syndrome and dry mouth patients
    Michael T Brennan
    National Institute of Dental and Craniofacial Research NIDCR, NIH, Bethesda, Maryland, USA
    Arthritis Rheum 47:189-95. 2002
    ..To investigate risk factors for positive minor salivary gland biopsy results in Sjögren's syndrome (SS) and dry mouth patients...
  16. ncbi A retrospective investigation of advanced periodontal disease as a risk factor for septicemia in hematopoietic stem cell and bone marrow transplant recipients
    Sunday O Akintoye
    Clinical Research Core and Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research NIDCR, National Institute of Health NIH, Bethesda, MD, 20892 4320 USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:581-8. 2002
    ..The primary aim of the present study was to determine impact of chronic periodontitis, as measured by radiographic alveolar bone loss, on septicemia and transplant mortality...
  17. ncbi Management of oral lesions in HIV-positive patients
    Lorena Baccaglini
    Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL 32610 3628, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S50.e1-23. 2007
    ..Finally, standardized outcome measures should be developed for future clinical trials to allow comparisons of studies using different populations...