Vira V Artym

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network
    Vira V Artym
    Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research Proteomics Core Facility, National Heart, Lung, and Blood Institute Biomolecular Engineering and Physical Sciences Shared Resource Program, National Institute of Biomolecular Imaging and Bioengineering Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research National Institutes of Health, Bethesda, MD 20892 Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical School and Department of Biostatistics, Bioinformatics, and Biomathematics Georgetown University, Washington, DC 20057
    J Cell Biol 208:331-50. 2015
  2. pmc Dynamic membrane remodeling at invadopodia differentiates invadopodia from podosomes
    Vira V Artym
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical School, Washington, DC 20057, USA
    Eur J Cell Biol 90:172-80. 2011
  3. ncbi request reprint Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function
    Vira V Artym
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical School, Washington, District of Columbia 20057 1469, USA
    Cancer Res 66:3034-43. 2006
  4. ncbi request reprint The matrix reorganized: extracellular matrix remodeling and integrin signaling
    Melinda Larsen
    Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, MSC 4370, Bethesda, MD 20892 4370, USA
    Curr Opin Cell Biol 18:463-71. 2006
  5. doi request reprint ECM degradation assays for analyzing local cell invasion
    Vira V Artym
    LCDB NIDCR, National Institutes of Health, Bethesda, MD 20892, USA
    Methods Mol Biol 522:211-9. 2009
  6. pmc Imaging cells in three-dimensional collagen matrix
    Vira V Artym
    Laboratory of Cell and Developmental Biology, NIDCR, NIH, Bethesda, Maryland, USA
    Curr Protoc Cell Biol . 2010
  7. pmc 3-D extracellular matrix from sectioned human tissues
    Catherine B Campbell
    Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland
    Curr Protoc Cell Biol 62:Unit 19.16.1-20. 2014

Detail Information

Publications7

  1. pmc Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network
    Vira V Artym
    Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research Proteomics Core Facility, National Heart, Lung, and Blood Institute Biomolecular Engineering and Physical Sciences Shared Resource Program, National Institute of Biomolecular Imaging and Bioengineering Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research National Institutes of Health, Bethesda, MD 20892 Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical School and Department of Biostatistics, Bioinformatics, and Biomathematics Georgetown University, Washington, DC 20057
    J Cell Biol 208:331-50. 2015
    ..This novel phosphosignaling mechanism regulates cell surface invadopodia via kindlin2 for local proteolytic remodeling of the ECM. ..
  2. pmc Dynamic membrane remodeling at invadopodia differentiates invadopodia from podosomes
    Vira V Artym
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical School, Washington, DC 20057, USA
    Eur J Cell Biol 90:172-80. 2011
    ....
  3. ncbi request reprint Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function
    Vira V Artym
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical School, Washington, District of Columbia 20057 1469, USA
    Cancer Res 66:3034-43. 2006
    ..Based on these results, we propose a stepwise model of invadopodia formation and function...
  4. ncbi request reprint The matrix reorganized: extracellular matrix remodeling and integrin signaling
    Melinda Larsen
    Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, MSC 4370, Bethesda, MD 20892 4370, USA
    Curr Opin Cell Biol 18:463-71. 2006
    ..These recent advances in the field provide new insights and raise new questions about the mechanisms of ECM synthesis and proteolytic degradation, as well as the roles of integrins and tension in ECM remodeling...
  5. doi request reprint ECM degradation assays for analyzing local cell invasion
    Vira V Artym
    LCDB NIDCR, National Institutes of Health, Bethesda, MD 20892, USA
    Methods Mol Biol 522:211-9. 2009
    ..In this chapter, we provide a detailed protocol for preparation of thin fluorescent gelatin matrices and for evaluation of the results from this degradation assay...
  6. pmc Imaging cells in three-dimensional collagen matrix
    Vira V Artym
    Laboratory of Cell and Developmental Biology, NIDCR, NIH, Bethesda, Maryland, USA
    Curr Protoc Cell Biol . 2010
    ..Additionally, the authors provide protocols for a "cell sandwiching" technique to prepare cell cultures in 3-D collagen matrices required for high-resolution confocal imaging...
  7. pmc 3-D extracellular matrix from sectioned human tissues
    Catherine B Campbell
    Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland
    Curr Protoc Cell Biol 62:Unit 19.16.1-20. 2014
    ..This unit also provides protocols for quality control of acellular matrix preparations, and for immunostaining of cells for specific cellular proteins as well as of extracellular matrices for their components...