Andrew E Arai

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Regadenoson and adenosine are equivalent vasodilators and are superior than dipyridamole- a study of first pass quantitative perfusion cardiovascular magnetic resonance
    Sujethra Vasu
    Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, 10 Center Drive, Building 10, Room B1D416, 20892 1061 Bethesda, MD, USA
    J Cardiovasc Magn Reson 15:85. 2013
  2. doi request reprint Magnetic resonance imaging for area at risk, myocardial infarction, and myocardial salvage
    Andrew E Arai
    Department of Health and Human Services, Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Cardiovasc Pharmacol Ther 16:313-20. 2011
  3. pmc The cardiac magnetic resonance (CMR) approach to assessing myocardial viability
    Andrew E Arai
    Cardiovascular and Pulmonary Branch, Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    J Nucl Cardiol 18:1095-102. 2011
  4. pmc Magnetic resonance imaging delineates the ischemic area at risk and myocardial salvage in patients with acute myocardial infarction
    Colin Berry
    Department of Health and Human Services, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circ Cardiovasc Imaging 3:527-35. 2010
  5. pmc Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology
    Martin Ugander
    Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, US Department of Health and Human Services, 10 Center Drive, Bethesda, MD 20892 1061, USA
    Eur Heart J 33:1268-78. 2012
  6. pmc MultiContrast Delayed Enhancement (MCODE) improves detection of subendocardial myocardial infarction by late gadolinium enhancement cardiovascular magnetic resonance: a clinical validation study
    W Patricia Bandettini
    Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute NHLBI, National Institutes of Health NIH, Department of Health and Human Services, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:83. 2012
  7. pmc Myocardial T1 and extracellular volume fraction mapping at 3 tesla
    Jason J Lee
    Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA
    J Cardiovasc Magn Reson 13:75. 2011
  8. pmc Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction
    Martin Ugander
    Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    JACC Cardiovasc Imaging 5:596-603. 2012
  9. pmc Late gadolinium-enhancement cardiac magnetic resonance identifies postinfarction myocardial fibrosis and the border zone at the near cellular level in ex vivo rat heart
    Erik B Schelbert
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1061, USA
    Circ Cardiovasc Imaging 3:743-52. 2010
  10. doi request reprint High spatial and temporal resolution cardiac cine MRI from retrospective reconstruction of data acquired in real time using motion correction and resorting
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 62:1557-64. 2009

Detail Information

Publications79

  1. pmc Regadenoson and adenosine are equivalent vasodilators and are superior than dipyridamole- a study of first pass quantitative perfusion cardiovascular magnetic resonance
    Sujethra Vasu
    Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, 10 Center Drive, Building 10, Room B1D416, 20892 1061 Bethesda, MD, USA
    J Cardiovasc Magn Reson 15:85. 2013
    ..The specific aim of this study was to determine the relative potency of these three vasodilators by quantifying stress and rest myocardial perfusion in humans using cardiovascular magnetic resonance (CMR)...
  2. doi request reprint Magnetic resonance imaging for area at risk, myocardial infarction, and myocardial salvage
    Andrew E Arai
    Department of Health and Human Services, Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Cardiovasc Pharmacol Ther 16:313-20. 2011
    ..Thus, the purpose of this review is to provide an overview of how MRI can determine the area at risk, infarct size, and thus measure myocardial salvage...
  3. pmc The cardiac magnetic resonance (CMR) approach to assessing myocardial viability
    Andrew E Arai
    Cardiovascular and Pulmonary Branch, Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    J Nucl Cardiol 18:1095-102. 2011
    ..Thus, CMR is a well validated technique that can assess viability by gadolinium-free dobutamine stress testing or late gadolinium enhancement...
  4. pmc Magnetic resonance imaging delineates the ischemic area at risk and myocardial salvage in patients with acute myocardial infarction
    Colin Berry
    Department of Health and Human Services, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circ Cardiovasc Imaging 3:527-35. 2010
    ..The area at risk (AAR) is a key determinant of myocardial infarction (MI) size. We investigated whether magnetic resonance imaging (MRI) measurement of AAR would be correlated with an angiographic AAR risk score in patients with acute MI...
  5. pmc Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology
    Martin Ugander
    Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, US Department of Health and Human Services, 10 Center Drive, Bethesda, MD 20892 1061, USA
    Eur Heart J 33:1268-78. 2012
    ....
  6. pmc MultiContrast Delayed Enhancement (MCODE) improves detection of subendocardial myocardial infarction by late gadolinium enhancement cardiovascular magnetic resonance: a clinical validation study
    W Patricia Bandettini
    Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute NHLBI, National Institutes of Health NIH, Department of Health and Human Services, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:83. 2012
    ..In this clinical validation study, our goal was to prospectively compare standard LGE imaging to MCODE in the detection of MI...
  7. pmc Myocardial T1 and extracellular volume fraction mapping at 3 tesla
    Jason J Lee
    Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA
    J Cardiovasc Magn Reson 13:75. 2011
    ..To compare 11 heartbeat (HB) and 17 HB modified lock locker inversion recovery (MOLLI) pulse sequence at 3T and to establish preliminary reference values for myocardial T1 and the extracellular volume fraction (ECV)...
  8. pmc Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction
    Martin Ugander
    Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    JACC Cardiovasc Imaging 5:596-603. 2012
    ..The aim of this study was to determine whether cardiac magnetic resonance (CMR) in vivo T1 mapping can measure myocardial area at risk (AAR) compared with microspheres or T2 mapping CMR...
  9. pmc Late gadolinium-enhancement cardiac magnetic resonance identifies postinfarction myocardial fibrosis and the border zone at the near cellular level in ex vivo rat heart
    Erik B Schelbert
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1061, USA
    Circ Cardiovasc Imaging 3:743-52. 2010
    ....
  10. doi request reprint High spatial and temporal resolution cardiac cine MRI from retrospective reconstruction of data acquired in real time using motion correction and resorting
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 62:1557-64. 2009
    ..s.). Motion-corrected averaging of real-time acquired cardiac images provides a means of attaining high-quality cine images with many of the benefits of real-time imaging, such as free-breathing acquisition and tolerance to arrhythmias...
  11. ncbi request reprint Prognosis of negative adenosine stress magnetic resonance in patients presenting to an emergency department with chest pain
    W Patricia Ingkanisorn
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, and Suburban Hospital, Bethesda, Maryland 20892 1061, USA
    J Am Coll Cardiol 47:1427-32. 2006
    ..This study was designed to determine the diagnostic value of adenosine cardiac magnetic resonance (CMR) in troponin-negative patients with chest pain...
  12. pmc T2* measurement during first-pass contrast-enhanced cardiac perfusion imaging
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 56:1132-4. 2006
    ..For single-dose Gd-DTPA (0.1 mmol/kg at 5 ml/s), the LV blood pool T(2) (*) had a mean value of 9 ms (N = 10) at peak enhancement. Distortion of the AIF due to T(2) (*) signal intensity loss will be less than 10% using TE = 0.6 ms...
  13. ncbi request reprint Motion corrected free-breathing delayed-enhancement imaging of myocardial infarction using nonrigid registration
    Maria J Ledesma-Carbayo
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    J Magn Reson Imaging 26:184-90. 2007
    ..To develop and test an automatic free-breathing, delayed enhancement imaging method with improved image signal-to-noise ratio (SNR)...
  14. pmc A quantitative pixel-wise measurement of myocardial blood flow by contrast-enhanced first-pass CMR perfusion imaging: microsphere validation in dogs and feasibility study in humans
    Li Yueh Hsu
    Advanced Cardiovascular Imaging Laboratory, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    JACC Cardiovasc Imaging 5:154-66. 2012
    ..The aim of this study was to evaluate fully quantitative myocardial blood flow (MBF) at a pixel level based on contrast-enhanced first-pass cardiac magnetic resonance (CMR) imaging in dogs and in patients...
  15. ncbi request reprint Stunned, infarcted, and normal myocardium in dogs: simultaneous differentiation by using gadolinium-enhanced cine MR imaging with magnetization transfer contrast
    Clifford R Weiss
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, 10 Center Dr, Bldg 10, Rm B1D416, MSC 1061, Bethesda, MD 20892 1061, USA
    Radiology 226:723-30. 2003
    ..To simultaneously differentiate stunned, infarcted, and normal myocardial regions by using gadolinium-enhanced cine magnetic resonance (MR) imaging with magnetization transfer contrast...
  16. ncbi request reprint Quantitative myocardial infarction on delayed enhancement MRI. Part I: Animal validation of an automated feature analysis and combined thresholding infarct sizing algorithm
    Li Yueh Hsu
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health DHHS, 10 Center Drive, Bethesda, MD 20892, USA
    J Magn Reson Imaging 23:298-308. 2006
    ..To develop a computer algorithm to measure myocardial infarct size in gadolinium-enhanced magnetic resonance (MR) imaging and to validate this method using a canine histopathological reference...
  17. ncbi request reprint Is functional capacity related to left atrial contractile function in nonobstructive hypertrophic cardiomyopathy?
    Yukitaka Shizukuda
    Cardiovascular Branch, National, Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Congest Heart Fail 11:234-40. 2005
    ..These data, obtained at rest, fail to suggest that NHCM-related heart failure symptoms are due to an atrial myopathy...
  18. ncbi request reprint DENSE with SENSE
    Anthony H Aletras
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    J Magn Reson 176:99-106. 2005
    ..Images from phantoms, normal volunteers, and a patient are provided to demonstrate the SENSE-DENSE combination of methods. The overall breath-hold time is halved while preserving strain map quality...
  19. doi request reprint Nonlinear myocardial signal intensity correction improves quantification of contrast-enhanced first-pass MR perfusion in humans
    Li Yueh Hsu
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    J Magn Reson Imaging 27:793-801. 2008
    ..To study the nonlinearity of myocardial signal intensity and gadolinium contrast concentration during first-pass perfusion MRI, and to compare quantitative perfusion estimates using nonlinear myocardial signal intensity correction...
  20. pmc Motion-corrected free-breathing delayed enhancement imaging of myocardial infarction
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, DHHS, 10 Center Drive, MSC 1061, Building 10, Room B1D416, Bethesda, MD 20892, USA
    Magn Reson Med 53:194-200. 2005
    ..In this study, motion correction was implemented using image registration postprocessing rather than navigator correction of individual frames. Navigator techniques may be incorporated as well...
  21. pmc Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction
    Felix M Gonzalez
    Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circulation 117:2986-94. 2008
    ....
  22. ncbi request reprint Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations
    Anthony H Aletras
    National Heart, Lung and Blood Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892 1061, USA
    Circulation 113:1865-70. 2006
    ....
  23. ncbi request reprint Reproducibility and inter-observer variability of dobutamine stress CMR in patients with severe coronary disease: implications for clinical research
    Mushabbar A Syed
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Cardiovasc Magn Reson 7:763-8. 2005
    ..The purpose of this study was to analyze reproducibility and inter-observer variability of dobutamine stress cardiac magnetic resonance imaging (dobutamine CMR) and its implications on serial studies...
  24. ncbi request reprint Quantitative myocardial infarction on delayed enhancement MRI. Part II: Clinical application of an automated feature analysis and combined thresholding infarct sizing algorithm
    Li Yueh Hsu
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health DHHS, 10 Center Drive, Bethesda, MD 20892, USA
    J Magn Reson Imaging 23:309-14. 2006
    ....
  25. doi request reprint Fully automatic, retrospective enhancement of real-time acquired cardiac cine MR images using image-based navigators and respiratory motion-corrected averaging
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Magn Reson Med 59:771-8. 2008
    ..Motion-corrected averaging of real-time acquired cardiac images provides a means of attaining high-quality cine images with many of the benefits of real-time imaging, such as free-breathing acquisition and tolerance to arrhythmias...
  26. ncbi request reprint Myocardial strain decreases with increasing transmurality of infarction: a Doppler echocardiographic and magnetic resonance correlation study
    Vandana Sachdev
    Echocardiography Laboratory, Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Am Soc Echocardiogr 19:34-9. 2006
    ..We studied longitudinal strain measurements in patients with evidence of myocardial infarction by cardiac magnetic resonance imaging to determine whether end-systolic strain could identify the severity of the infarction...
  27. ncbi request reprint Gadolinium delayed enhancement cardiovascular magnetic resonance correlates with clinical measures of myocardial infarction
    W Patricia Ingkanisorn
    National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    J Am Coll Cardiol 43:2253-9. 2004
    ..Acute infarct mass by cardiac magnetic resonance (CMR) was compared with peak troponin I, acute and chronic left ventricular (LV) systolic function, and chronic infarct mass in patients imaged after recent acute MI...
  28. pmc Multi-contrast delayed enhancement provides improved contrast between myocardial infarction and blood pool
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    J Magn Reson Imaging 22:605-13. 2005
    ..To develop and test a delayed-enhancement imaging method for improving the contrast between myocardial infarction (MI) and blood pool...
  29. ncbi request reprint In vivo T2-weighted magnetic resonance imaging can accurately determine the ischemic area at risk for 2-day-old nonreperfused myocardial infarction
    Gauri S Tilak
    National Heart, Lung and Blood Institute, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    Invest Radiol 43:7-15. 2008
    ..AAR was defined as the size of the perfusion defect on day 0. MI and the residual ischemic viable border zone comprise the AAR...
  30. pmc Extracellular volume fraction mapping in the myocardium, part 2: initial clinical experience
    Peter Kellman
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:64. 2012
    ..We hypothesized that quantitative assessment of myocardial ECV would be clinically useful for detecting both focal and diffuse myocardial abnormalities in a variety of common and uncommon heart diseases...
  31. pmc Artifact suppression in imaging of myocardial infarction using B1-weighted phased-array combined phase-sensitive inversion recovery
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 51:408-12. 2004
    ..Example images are shown that illustrate the suppression of CSF ghost artifacts by the use of B1-weighted phased-array combining of multiple receiver coils...
  32. ncbi request reprint Age-related vascular stiffness and left ventricular size after myocardial infarction
    Glenn A Hirsch
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Geriatr Cardiol 16:222-8. 2007
    ..02) were significant predictors of end-systolic volume index. Older patients have increased LV size after MI compared with younger patients, possibly related to age-related decreases in aortic distensibility affecting LV remodeling...
  33. pmc Heterogeneity of intramural function in hypertrophic cardiomyopathy: mechanistic insights from MRI late gadolinium enhancement and high-resolution displacement encoding with stimulated echoes strain maps
    Anthony H Aletras
    Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1061, USA
    Circ Cardiovasc Imaging 4:425-34. 2011
    ..The aim of this study was to determine whether excess collagen or myocardial scarring, as determined by LGE MRI, are the primary mechanisms leading to heterogeneous regional contractile function in patients with HCM...
  34. pmc T2-prepared SSFP improves diagnostic confidence in edema imaging in acute myocardial infarction compared to turbo spin echo
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 57:891-7. 2007
    ..Free-breathing T2 prepared SSFP provides T2-weighted images of acute MI with fewer artifacts and better diagnostic accuracy than conventional dark-blood TSE...
  35. doi request reprint Bright-blood T(2)-weighted MRI has high diagnostic accuracy for myocardial hemorrhage in myocardial infarction: a preclinical validation study in swine
    Alexander R Payne
    National Heart, Lung, and Blood Institute, National Institutes of Health, DHHS, Bethesda, MD 20892 1061, USA
    Circ Cardiovasc Imaging 4:738-45. 2011
    ..Myocardial hemorrhage after myocardial infarction (MI) usually goes undetected. We investigated the diagnostic accuracy of bright-blood T(2)-weighted cardiac MRI for myocardial hemorrhage in experimental MI...
  36. ncbi request reprint Manganese enhanced magnetic resonance imaging of normal and ischemic canine heart
    Tom C C Hu
    Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 54:196-200. 2005
    ..03). In conclusion, the intracellular contrast agent MnCl2 enhances the canine heart and shows promise in detecting ischemia at doses that do not cause adverse cardiac effects...
  37. pmc Partition coefficients for gadolinium chelates in the normal myocardium: comparison of gadopentetate dimeglumine and gadobenate dimeglumine
    Nadine Kawel
    Radiology and Imaging Sciences, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    J Magn Reson Imaging 36:733-7. 2012
    ....
  38. pmc Trabeculated (noncompacted) and compact myocardium in adults: the multi-ethnic study of atherosclerosis
    Nadine Kawel
    Radiology and Imaging Sciences and National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA
    Circ Cardiovasc Imaging 5:357-66. 2012
    ..The purpose of this study was to determine the normal range of the T/M ratio in a large population-based study and to examine the relationship to demographic and clinical parameters...
  39. pmc Multiecho dixon fat and water separation method for detecting fibrofatty infiltration in the myocardium
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 61:215-21. 2009
    ..The multiecho Dixon method for fat and water separation provides a sensitive means of detecting intramyocardial fat with positive signal contrast...
  40. ncbi request reprint Quantitative myocardial perfusion analysis with a dual-bolus contrast-enhanced first-pass MRI technique in humans
    Li Yueh Hsu
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health DHHS, 10 Center Drive, Bethesda, MD 20892, USA
    J Magn Reson Imaging 23:315-22. 2006
    ..To compare fully quantitative and semiquantitative analysis of rest and stress myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) using a dual-bolus first-pass perfusion MRI method in humans...
  41. ncbi request reprint Absolute myocardial perfusion in canines measured by using dual-bolus first-pass MR imaging
    Timothy F Christian
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bldg 10, Rm B1D416, MSC 1061, 10 Center Dr, Bethesda, MD 20892 1061, USA
    Radiology 232:677-84. 2004
    ..To compare fluorescent microsphere measurements of myocardial blood flow (MBF) with qualitative, semiquantitative, and fully quantitative measurements of first-pass perfusion at magnetic resonance (MR) imaging...
  42. doi request reprint Spectrum of aortic valve abnormalities associated with aortic dilation across age groups in Turner syndrome
    Laura J Olivieri
    National Institute of Child Health and Human Development and National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
    Circ Cardiovasc Imaging 6:1018-23. 2013
    ..Our objective was to characterize aortic valve structure in subjects with Turner syndrome and to determine the prevalence of aortic dilation and valve dysfunction associated with different types of aortic valves...
  43. pmc Extracellular volume fraction mapping in the myocardium, part 1: evaluation of an automated method
    Peter Kellman
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:63. 2012
    ..The goal of this study was to develop and evaluate an automated method for producing a pixel-wise map of ECV that would be adequately robust for clinical work flow...
  44. pmc Retrospective reconstruction of high temporal resolution cine images from real-time MRI using iterative motion correction
    Michael S Hansen
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 68:741-50. 2012
    ..92, (d) Radial motion correction: 4.58, and (e) Breath-hold cine: 5.00. The proposed method provides a flexible way to obtain high-quality, high-resolution cine images in patients with difficulty holding their breath...
  45. pmc Gadolinium-enhanced cardiovascular magnetic resonance: administered dose in relationship to United States Food and Drug Administration (FDA) guidelines
    Marcelo S Nacif
    Radiology and Imaging Sciences National Institutes of Health Clinical Center, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:18. 2012
    ..The relationship of gadolinium dose warnings (due to nephrogenic systemic fibrosis) announced in 2008 to gadolinium dosing regimens was also examined...
  46. doi request reprint Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults
    Erik B Schelbert
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    JAMA 308:890-6. 2012
    ..Unrecognized myocardial infarction (MI) is prognostically important. Electrocardiography (ECG) has limited sensitivity for detecting unrecognized MI (UMI)...
  47. pmc Direct injection of autologous mesenchymal stromal cells improves myocardial function
    Yifu Zhou
    Cellular Biology Section, Cardiothoracic Surgery Research Program, NHLBI, National Institutes of Health, 10 Center Drive, MSC 1550, Building 10, Room 2N246, Bethesda, MD 20892 1550, USA
    Biochem Biophys Res Commun 390:902-7. 2009
    ..This suggests that the angiogenesis engendered by cell treatment may be physiologically meaningful by improving the contractility of ischemic myocardium...
  48. doi request reprint ACUT2E TSE-SSFP: a hybrid method for T2-weighted imaging of edema in the heart
    Anthony H Aletras
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health DHHS, 10 Center Drive, Bethesda, MD 20892, USA
    Magn Reson Med 59:229-35. 2008
    ..Imperfect blood suppression, present in all animals on some TSE images, was a problem eliminated by TSE-SSFP and T2-prepared SSFP...
  49. ncbi request reprint Automatic assessment of dynamic contrast-enhanced MRI in an ischemic rat hindlimb model: an exploratory study of transplanted multipotent progenitor cells
    Li Yueh Hsu
    National Heart Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1061, USA
    NMR Biomed 21:111-9. 2008
    ..The differences were primarily determined by late contrast enhancement of PBS-treated limbs. These computerized methods appear promising for assessing perfusion and late enhancement in dynamic contrast-enhanced MRI...
  50. pmc N-terminal pro-brain natriuretic peptide levels and aortic diameters
    Liat S Gutin
    Section on Epigenetics and Development, National Institute of Child Health and Human Development, Bethesda, MD, USA
    Am Heart J 164:419-24. 2012
    ..To better understand the pathology and develop tools to monitor the risk of aortic disease, we investigated N-terminal pro-brain natriuretic peptide (BNP) (NT-proBNP) levels in women with TS and healthy female controls...
  51. ncbi request reprint Pulmonary vein imaging: comparison of 3D magnetic resonance angiography with 2D cine MRI for characterizing anatomy and size
    Mushabbar A Syed
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, Department of Health and Human Services, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    J Cardiovasc Magn Reson 7:355-60. 2005
    ..We suggest a protocol combining 2D cine CMR and 3D MRA for comprehensive evaluation of pulmonary veins...
  52. ncbi request reprint AIR-SPAMM: alternative inversion recovery spatial modulation of magnetization for myocardial tagging
    Anthony H Aletras
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Building 10, Room B1D416, MSC 1061, Bethesda, MD 20892 1061, USA
    J Magn Reson 166:236-45. 2004
    ..AIR-SPAMM can be used either for imaging systole as demonstrated by initial in vivo results or potentially for imaging the entire cardiac cycle in a slice-interleaved manner...
  53. ncbi request reprint Determining canine myocardial area at risk with manganese-enhanced MR imaging
    Alex Natanzon
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, U S Department of Health and Human Services, 10 Center Dr, MSC 1061, Bldg 10, Room B1D 416, Bethesda, MD 20892 1061, USA
    Radiology 236:859-66. 2005
    ..To test whether manganese-enhanced magnetic resonance (MR) imaging can safely depict the myocardial area at risk both during coronary artery occlusion and for at least 2 hours after reperfusion in dogs...
  54. ncbi request reprint meta-DENSE complex acquisition for reduced intravoxel dephasing
    Anthony H Aletras
    Laboratory of Cardiac Energetics, US Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Heath, Bethesda, MD, USA
    J Magn Reson 169:246-9. 2004
    ....
  55. ncbi request reprint Imaging sequences for first pass perfusion --a review
    Peter Kellman
    Laboratory of Cardiac Energetics, Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    J Cardiovasc Magn Reson 9:525-37. 2007
    ..Understanding the interaction between the pulse sequence parameters and resulting image quality is important for improving myocardial perfusion imaging...
  56. doi request reprint Aortic valve disease in Turner syndrome
    Vandana Sachdev
    National Heart, Lung and Blood Institute, Bethesda, Maryland 20892, USA
    J Am Coll Cardiol 51:1904-9. 2008
    ..Our goal was to determine the prevalence and characteristics of aortic valve disease in girls and women with monosomy for the X chromosome, or Turner syndrome (TS)...
  57. pmc The impact of obesity on the left ventricle: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Evrim B Turkbey
    Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Maryland 20892, USA
    JACC Cardiovasc Imaging 3:266-74. 2010
    ..The purpose of this study was to evaluate the relationship of left ventricular (LV) remodeling assessed by cardiac magnetic resonance to various measures of obesity in a large population-based study...
  58. pmc T1 and extracellular volume mapping in the heart: estimation of error maps and the influence of noise on precision
    Peter Kellman
    National Heart, Lung, and Blood Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
    J Cardiovasc Magn Reson 15:56. 2013
    ....
  59. ncbi request reprint Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging
    Raymond Y Kwong
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Circulation 107:531-7. 2003
    ..Managing chest pain in the emergency department remains a challenge with current diagnostic strategies. We hypothesized that cardiac MRI could accurately identify patients with possible or probable acute coronary syndrome...
  60. pmc Cardiac imaging techniques for physicians: late enhancement
    Peter Kellman
    National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Magn Reson Imaging 36:529-42. 2012
    ..The aim of this review will be to describe the current state of the art and to provide a guide to various clinical protocols that are commonly used...
  61. pmc Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells
    Caterina Bianco
    Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Am J Pathol 175:2146-58. 2009
    ....
  62. ncbi request reprint Nonsyndromic hearing loss DFNA10 and a novel mutation of EYA4: evidence for correlation of normal cardiac phenotype with truncating mutations of the Eya domain
    Tomoko Makishima
    Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville 20850 3320, Maryland, USA
    Am J Med Genet A 143:1592-8. 2007
    ..These results will facilitate the counseling of patients with these phenotypes and EYA4 mutations...
  63. doi request reprint Diagnostic Accuracy of Stress Perfusion CMR in Comparison With Quantitative Coronary Angiography: Fully Quantitative, Semiquantitative, and Qualitative Assessment
    Federico E Mordini
    Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland Department of Cardiology, Veterans Affairs Medical Center, Washington, DC
    JACC Cardiovasc Imaging 7:14-22. 2014
    ....
  64. ncbi request reprint Multislice first-pass cardiac perfusion MRI: validation in a model of myocardial infarction
    Frederick H Epstein
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 47:482-91. 2002
    ..Additionally, analysis of myocardial time-intensity curves (TICs) indicated that 15.8 +/- 6 sectors, corresponding to 260 microl of endocardium, can be analyzed (R(2) > 0.95)...
  65. pmc Submillisievert median radiation dose for coronary angiography with a second-generation 320-detector row CT scanner in 107 consecutive patients
    Marcus Y Chen
    Advanced Cardiovascular Imaging Laboratory, Cardiovascular and Pulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, 10 Center Dr, Building 10, Room B1D416, Bethesda, MD 20892 1061, USA
    Radiology 267:76-85. 2013
    ....
  66. doi request reprint Off-pump surgery for giant right coronary artery aneurysms
    Abbas Emaminia
    National Institutes of Health NIH Heart Center, Bethesda, Maryland, USA
    J Card Surg 26:596-9. 2011
    ..We report two cases of giant right coronary artery aneurysms successfully treated by off-pump resection of the aneurysm and bypass grafting. The controversy surrounding the proper management of such cases is discussed...
  67. pmc Myocardial T1 mapping with MRI: comparison of look-locker and MOLLI sequences
    Marcelo Souto Nacif
    Radiology and Imaging Sciences National Institutes of Health Clinical Center, Bethesda, MD, USA Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA Radiology Department, Universidade Federal Fluminense, Niteroi, Brazil
    J Magn Reson Imaging 34:1367-73. 2011
    ..To evaluate the relationship between "Look-Locker" (LL) and modified Look-Locker Inversion recovery (MOLLI) approaches for T1 mapping of the myocardium...
  68. ncbi request reprint Cardiac magnetic resonance appearance of myocarditis caused by high dose IL-2: similarities to community-acquired myocarditis
    W Patricia Ingkanisorn
    National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    J Cardiovasc Magn Reson 8:353-60. 2006
    ..The location, pattern, and extent of DE were similar in both groups of patients. The CMR similarities between these two populations suggest that cytokine-mediated cytotoxicity may play an important role in community-acquired myocarditis...
  69. ncbi request reprint Long-term safety of cardiac magnetic resonance imaging performed in the first few days after bare-metal stent implantation
    Mushabbar A Syed
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Magn Reson Imaging 24:1056-61. 2006
    ..To investigate the long-term safety of cardiac magnetic resonance imaging (CMR) performed one to seven days after coronary artery stent (bare metal) implantation...
  70. pmc Cardiac involvement with lymphoma: a review of the literature
    Deirdre O'Mahony
    Metabolism Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Clin Lymphoma Myeloma 8:249-52. 2008
    ..We present 2 cases and a review of the literature...
  71. pmc Imaging of myocardial infarction for diagnosis and intervention using real-time interactive MRI without ECG-gating or breath-holding
    Michael A Guttman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 52:354-61. 2004
    ..Supplementary material for this article can be found on the MRM website at http://www.interscience.wiley.com/jpages/0740-3194/suppmat/index.html...
  72. ncbi request reprint Qualitative assessment of regional left ventricular function can predict MRI or radionuclide ejection fraction: an objective alternative to eyeball estimates
    Lilia M Sierra-Galan
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bldg 10, B1D61, MSC 1061, 10 Center Drive, Bethesda, MD 20892, USA
    J Cardiovasc Magn Reson 5:451-63. 2003
    ..We hypothesized that regional wall motion assessed qualitatively by cine magnetic resonance imaging (MRI) can predict the left ventricular ejection fraction (EF)...
  73. doi request reprint Coronary artery anomalies and variants: technical feasibility of assessment with coronary MR angiography at 3 T
    Ahmed M Gharib
    Department of Diagnostic Radiology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Radiology 247:220-7. 2008
    ..Findings included aneurysms, ectasia, arteriovenous fistulas, and anomalous origins. The 3D whole-heart acquisitions developed for use with 3 T are feasible for use in the assessment of CAAV...
  74. ncbi request reprint Coronary artery aneurysms in patients with hyper IgE recurrent infection syndrome
    Jennifer C Ling
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Clin Immunol 122:255-8. 2007
    ..Further studies are necessary to determine the incidence, pathogenesis, and optimal therapy of these arterial abnormalities in HIES...
  75. ncbi request reprint Left atrial volumetric remodeling is predictive of functional capacity in nonobstructive hypertrophic cardiomyopathy
    Vandana Sachdev
    Echocardiography Laboratory, Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am Heart J 149:730-6. 2005
    ..We examined the relationship between left atrial volumetric remodeling and objective measures of exercise capacity in patients with nonobstructive hypertrophic cardiomyopathy (HCM)...
  76. pmc Outcomes and risks of granulocyte colony-stimulating factor in patients with coronary artery disease
    Jonathan M Hill
    Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1650, USA
    J Am Coll Cardiol 46:1643-8. 2005
    ..Cytokine mobilization of progenitor cells from bone marrow may promote myocardial neovascularization with relief of ischemia...
  77. ncbi request reprint Stem cells for myocardial regeneration
    Donald Orlic
    Genetics and Molecular Biology Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892 4442, USA
    Circ Res 91:1092-102. 2002
    ..Only then will we be able to regulate this process and begin to realize the full potential of stem cells in regenerative medicine...
  78. ncbi request reprint Effect of hormone replacement therapy on carotid arterial compliance in healthy postmenopausal women
    Minh N Bui
    Cardiovascular Branch, Laboratory of Cardiac Energetics, Office of Biostatistics Research, National Heart, Lung and Blood Institute, Clinical Pathology Department, National Institutes of Health, Bethesda, Maryland 20892 1650, USA
    Am J Cardiol 90:82-5. 2002
  79. pmc Phase-sensitive inversion recovery for detecting myocardial infarction using gadolinium-delayed hyperenhancement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 47:372-83. 2002
    ..Phase-sensitive detection also has the advantage of decreasing the sensitivity to changes in tissue T(1) with increasing delay from contrast agent injection...