Gabriella Andreotti

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, China
    G Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
    Br J Cancer 102:1185-9. 2010
  2. doi request reprint Medical history and the risk of biliary tract cancers in Shanghai, China: implications for a role of inflammation
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Causes Control 22:1289-96. 2011
  3. pmc Variants in blood pressure genes and the risk of renal cell carcinoma
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852 4906, USA
    Carcinogenesis 31:614-20. 2010
  4. pmc Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, China
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD, 20892, USA
    Eur J Epidemiol 24:763-74. 2009
  5. pmc Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study Cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 124:2495-500. 2009
  6. pmc Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Causes Control 21:1759-75. 2010
  7. doi request reprint Occupational risk factors and pancreatic cancer: a review of recent findings
    Gabriella Andreotti
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Mol Carcinog 51:98-108. 2012
  8. pmc Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:525-34. 2008
  9. pmc Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20892 7240, USA
    Carcinogenesis 33:331-7. 2012
  10. pmc Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7240, USA
    Environ Health Perspect 119:1726-32. 2011

Detail Information

Publications29

  1. pmc Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, China
    G Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
    Br J Cancer 102:1185-9. 2010
    ..Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear...
  2. doi request reprint Medical history and the risk of biliary tract cancers in Shanghai, China: implications for a role of inflammation
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Causes Control 22:1289-96. 2011
    ..2-15.0) or duodenal ulcers (OR = 3.7, 1.2-12.0) was associated with an excess risk of gallbladder cancer. Although the mechanisms are unclear, our results further support the role for inflammation in the etiology of biliary tract cancers...
  3. pmc Variants in blood pressure genes and the risk of renal cell carcinoma
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852 4906, USA
    Carcinogenesis 31:614-20. 2010
    ..003). Our findings suggest that common genetic variants of AGT, particularly those in the promoter, increase RCC risk among subjects who are hypertensive or overweight...
  4. pmc Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, China
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD, 20892, USA
    Eur J Epidemiol 24:763-74. 2009
    ..These findings provide insight into the role of lipid metabolism genes, as well as the mechanisms by which these genes may be linked with disease...
  5. pmc Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study Cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 124:2495-500. 2009
    ..Organochlorines were not associated with an excess risk of pancreatic cancer in this study. These findings suggest that herbicides, particularly pendimethalin and EPTC, may be associated with pancreatic cancer...
  6. pmc Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Causes Control 21:1759-75. 2010
    ..87, 95% CI = 0.82-0.92) but was null in users of carbofuran (p-interaction = 0.02). These findings suggest that certain pesticides may modify the effects of BMI on the risks of colon and lung cancers...
  7. doi request reprint Occupational risk factors and pancreatic cancer: a review of recent findings
    Gabriella Andreotti
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Mol Carcinog 51:98-108. 2012
    ..We conclude that the strongest and most consistent findings linking occupational exposures with pancreatic cancer risk to date are for chlorinated hydrocarbons and PAHs...
  8. pmc Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:525-34. 2008
    ..5-fold risk of bile duct cancer. Our findings suggest that gene variants in the lipid metabolism pathway contribute to the risk of biliary tract stones and cancers, particularly of the bile duct...
  9. pmc Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20892 7240, USA
    Carcinogenesis 33:331-7. 2012
    ..09). In contrast, we did not observe associations among men with other genotypes at these loci. While requiring replication, our findings suggest a role for NER genetic variation in pesticide-associated prostate cancer risk...
  10. pmc Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7240, USA
    Environ Health Perspect 119:1726-32. 2011
    ..Previous research indicates increased prostate cancer risk for pesticide applicators and pesticide manufacturing workers. Although underlying mechanisms are unknown, evidence suggests a role of oxidative DNA damage...
  11. pmc Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China
    Shih Chen Chang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
    Carcinogenesis 29:944-8. 2008
    ..Results from this population-based study suggest that certain genetic variants involved in the regulation of obesity-related insulin sensitivity may increase susceptibility to bile duct cancer and gallstones...
  12. pmc Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China
    Sue K Park
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, EPS 5024, MSC 7234, Bethesda, MD 20892 7234, USA
    Carcinogenesis 30:606-14. 2009
    ..1-4.9; P-interaction = 0.05) was statistically significant. Our findings suggest that common variants in hormone-related genes contribute to the risk of biliary tract cancers and stones, possibly by modulating hormone metabolism...
  13. pmc Variants of DNA repair genes and the risk of biliary tract cancers and stones: a population-based study in China
    Mingdong Zhang
    Food and Drug Administration, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 17:2123-7. 2008
    ..Findings from this population-based study in Shanghai suggest that MGMT gene variants may alter susceptibility to biliary tract cancer, particularly gallbladder cancer. Confirmation in future studies, however, is required...
  14. pmc Serum lipid levels and the risk of biliary tract cancers and biliary stones: A population-based study in China
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA
    Int J Cancer 122:2322-9. 2008
    ..Our findings support a role for serum lipids in gallstone development and biliary carcinogenesis...
  15. pmc Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China
    Ann W Hsing
    Division of Cancer Epidemiology and Genetics and Office of Preventive Oncology, National Cancer Institute, NIH, Bethesda, Maryland 20892 7234, USA
    Cancer Res 68:6442-52. 2008
    ....
  16. pmc Risk of total and aggressive prostate cancer and pesticide use in the Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8115, MSC 7240, Rockville, MD 20852, USA
    Am J Epidemiol 177:59-74. 2013
    ..Furthermore, this is the first time specific pesticides are implicated as risk factors for aggressive prostate cancer...
  17. pmc Polymorphisms of estrogen receptors and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, China
    Sue K Park
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, EPS MSC 7234, 6120 Executive Boulevard, Bethesda, MD 20892 7234, USA
    Carcinogenesis 31:842-6. 2010
    ..1). No association was found for ESR1 haplotype based on four SNPs. These preliminary results suggest that variants in ESR genes could play a role in the etiology of biliary tract cancers, especially bile duct cancer in men...
  18. pmc Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 70:9224-33. 2010
    ..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk...
  19. pmc Atrazine and cancer incidence among pesticide applicators in the agricultural health study (1994-2007)
    Laura E Beane Freeman
    Division of Cancer, Epidemiology, and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Environ Health Perspect 119:1253-9. 2011
    ..Atrazine is a triazine herbicide used widely in the United States. Although it is an animal carcinogen, the mechanism in rodents does not appear to operate in humans. Few epidemiologic studies have provided evidence for an association...
  20. pmc Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Pharmacogenet Genomics 21:615-23. 2011
    ..OBECTIVE: We evaluated pesticide-SNP interactions between 45 pesticides and 1913 XME SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural Health Study...
  21. pmc Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China
    Felipe A Castro
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Rockville, MD 20892, USA
    BMC Cancer 12:468. 2012
    ..Genetic variants in inflammation-related genes have been associated with biliary stones and biliary tract cancers in previous studies...
  22. pmc Family history of gallstones and the risk of biliary tract cancer and gallstones: a population-based study in Shanghai, China
    Ann W Hsing
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20852, USA
    Int J Cancer 121:832-8. 2007
    ....
  23. pmc Genetic susceptibility loci, pesticide exposure and prostate cancer risk
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 8:e58195. 2013
    ..Although additional studies are needed and the exact mechanisms are unknown, this study suggests known genetic susceptibility loci may modify the risk between pesticide use and prostate cancer...
  24. pmc Androgen receptor CAG repeat length and risk of biliary tract cancer and stones
    Tamra E Meyer
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS Room 5032, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 19:787-93. 2010
    ..Further studies are needed to confirm these findings and clarify the mechanisms involved...
  25. pmc Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health Study
    Sonya L Heltshe
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    J Expo Sci Environ Epidemiol 22:409-16. 2012
    ..When appropriately implemented, multiple imputation can reduce bias and increase precision and can be more valid than other missing data approaches...
  26. pmc Pesticide exposure and inherited variants in vitamin d pathway genes in relation to prostate cancer
    Sara Karami
    Authors Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville Core Genotyping Facility, National Cancer Institute Frederick, SAIC Frederick Inc, Frederick, Maryland and Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina
    Cancer Epidemiol Biomarkers Prev 22:1557-66. 2013
    ..Certain pesticides have been shown to deregulate vitamin D's anticarcinogenic properties. We hypothesize that certain pesticides may be linked to prostate cancer via an interaction with vitamin D genetic variants...
  27. pmc Risk-accepting personality and personal protective equipment use within the Agricultural Health Study
    Curt T Dellavalle
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Agromedicine 17:264-76. 2012
    ..21, 95% CI: 1.01-1.44), compared to further than ΒΌ mile. These findings suggest that the decisions to use personal protective equipment and properly handle/apply pesticides may be driven by risk-accepting personality traits...
  28. pmc Heterocyclic aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Int J Cancer 124:1206-12. 2009
    ..The use of imazethapyr and other imidazolinone compounds should continue to be evaluated for potential risk to humans...
  29. pmc Tea drinking and the risk of biliary tract cancers and biliary stones: a population-based case-control study in Shanghai, China
    Xue hong Zhang
    Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China
    Int J Cancer 118:3089-94. 2006
    ..0, but were not statistically significant. Further studies are needed to confirm these results in other populations and clarify the hormonal and other mechanisms that may be involved...