Research Topics
Genomes and Genes
| Gabriella AndreottiSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, ChinaGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD, 20892, USA
Eur J Epidemiol 24:763-74. 2009..These findings provide insight into the role of lipid metabolism genes, as well as the mechanisms by which these genes may be linked with disease...
Medical history and the risk of biliary tract cancers in Shanghai, China: implications for a role of inflammationGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
Cancer Causes Control 22:1289-96. 2011..2-15.0) or duodenal ulcers (OR = 3.7, 1.2-12.0) was associated with an excess risk of gallbladder cancer. Although the mechanisms are unclear, our results further support the role for inflammation in the etiology of biliary tract cancers...- Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohortGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
Cancer Causes Control 21:1759-75. 2010..87, 95% CI = 0.82-0.92) but was null in users of carbofuran (p-interaction = 0.02). These findings suggest that certain pesticides may modify the effects of BMI on the risks of colon and lung cancers... - Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, ChinaGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 17:525-34. 2008..5-fold risk of bile duct cancer. Our findings suggest that gene variants in the lipid metabolism pathway contribute to the risk of biliary tract stones and cancers, particularly of the bile duct... - Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, ChinaG Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
Br J Cancer 102:1185-9. 2010..Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear... - Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study CohortGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Int J Cancer 124:2495-500. 2009..Organochlorines were not associated with an excess risk of pancreatic cancer in this study. These findings suggest that herbicides, particularly pendimethalin and EPTC, may be associated with pancreatic cancer... - Variants in blood pressure genes and the risk of renal cell carcinomaGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852 4906, USA
Carcinogenesis 31:614-20. 2010..003). Our findings suggest that common genetic variants of AGT, particularly those in the promoter, increase RCC risk among subjects who are hypertensive or overweight... - Occupational risk factors and pancreatic cancer: a review of recent findingsGabriella Andreotti
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Mol Carcinog 51:98-108. 2012..We conclude that the strongest and most consistent findings linking occupational exposures with pancreatic cancer risk to date are for chlorinated hydrocarbons and PAHs... - Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer riskKathryn Hughes Barry
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20892 7240, USA
Carcinogenesis 33:331-7. 2012..09). In contrast, we did not observe associations among men with other genotypes at these loci. While requiring replication, our findings suggest a role for NER genetic variation in pesticide-associated prostate cancer risk... - Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer riskKathryn Hughes Barry
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7240, USA
Environ Health Perspect 119:1726-32. 2011..Previous research indicates increased prostate cancer risk for pesticide applicators and pesticide manufacturing workers. Although underlying mechanisms are unknown, evidence suggests a role of oxidative DNA damage... - Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, ChinaShih Chen Chang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
Carcinogenesis 29:944-8. 2008..Results from this population-based study suggest that certain genetic variants involved in the regulation of obesity-related insulin sensitivity may increase susceptibility to bile duct cancer and gallstones... - Variants of DNA repair genes and the risk of biliary tract cancers and stones: a population-based study in ChinaMingdong Zhang
Food and Drug Administration, Rockville, Maryland, USA
Cancer Epidemiol Biomarkers Prev 17:2123-7. 2008..Findings from this population-based study in Shanghai suggest that MGMT gene variants may alter susceptibility to biliary tract cancer, particularly gallbladder cancer. Confirmation in future studies, however, is required... - Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in ChinaSue K Park
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, EPS 5024, MSC 7234, Bethesda, MD 20892 7234, USA
Carcinogenesis 30:606-14. 2009..1-4.9; P-interaction = 0.05) was statistically significant. Our findings suggest that common variants in hormone-related genes contribute to the risk of biliary tract cancers and stones, possibly by modulating hormone metabolism... - Serum lipid levels and the risk of biliary tract cancers and biliary stones: A population-based study in ChinaGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA
Int J Cancer 122:2322-9. 2008..Our findings support a role for serum lipids in gallstone development and biliary carcinogenesis... - Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in ChinaAnn W Hsing
Division of Cancer Epidemiology and Genetics and Office of Preventive Oncology, National Cancer Institute, NIH, Bethesda, Maryland 20892 7234, USA
Cancer Res 68:6442-52. 2008.... - Risk of total and aggressive prostate cancer and pesticide use in the Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8115, MSC 7240, Rockville, MD 20852, USA
Am J Epidemiol 177:59-74. 2013..Furthermore, this is the first time specific pesticides are implicated as risk factors for aggressive prostate cancer... - Polymorphisms of estrogen receptors and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, ChinaSue K Park
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, EPS MSC 7234, 6120 Executive Boulevard, Bethesda, MD 20892 7234, USA
Carcinogenesis 31:842-6. 2010..1). No association was found for ESR1 haplotype based on four SNPs. These preliminary results suggest that variants in ESR genes could play a role in the etiology of biliary tract cancers, especially bile duct cancer in men... - Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 70:9224-33. 2010..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk... - Atrazine and cancer incidence among pesticide applicators in the agricultural health study (1994-2007)Laura E Beane Freeman
Division of Cancer, Epidemiology, and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Environ Health Perspect 119:1253-9. 2011..Atrazine is a triazine herbicide used widely in the United States. Although it is an animal carcinogen, the mechanism in rodents does not appear to operate in humans. Few epidemiologic studies have provided evidence for an association... - Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
Pharmacogenet Genomics 21:615-23. 2011..OBECTIVE: We evaluated pesticide-SNP interactions between 45 pesticides and 1913 XME SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural Health Study... - Family history of gallstones and the risk of biliary tract cancer and gallstones: a population-based study in Shanghai, ChinaAnn W Hsing
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20852, USA
Int J Cancer 121:832-8. 2007.... - Androgen receptor CAG repeat length and risk of biliary tract cancer and stonesTamra E Meyer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS Room 5032, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 19:787-93. 2010..Further studies are needed to confirm these findings and clarify the mechanisms involved... - Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health StudySonya L Heltshe
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
J Expo Sci Environ Epidemiol 22:409-16. 2012..When appropriately implemented, multiple imputation can reduce bias and increase precision and can be more valid than other missing data approaches... - Risk-accepting personality and personal protective equipment use within the Agricultural Health StudyCurt T Dellavalle
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Agromedicine 17:264-76. 2012..21, 95% CI: 1.01-1.44), compared to further than ΒΌ mile. These findings suggest that the decisions to use personal protective equipment and properly handle/apply pesticides may be driven by risk-accepting personality traits... - Heterocyclic aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Int J Cancer 124:1206-12. 2009..The use of imazethapyr and other imidazolinone compounds should continue to be evaluated for potential risk to humans... - Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in ChinaFelipe A Castro
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Rockville, MD 20892, USA
BMC Cancer 12:468. 2012..Genetic variants in inflammation-related genes have been associated with biliary stones and biliary tract cancers in previous studies... - Tea drinking and the risk of biliary tract cancers and biliary stones: a population-based case-control study in Shanghai, ChinaXue-Hong Zhang
Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China
Int J Cancer 118:3089-94. 2006..0, but were not statistically significant. Further studies are needed to confirm these results in other populations and clarify the hormonal and other mechanisms that may be involved...