Laufey Amundadottir

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33
    Hemang Parikh
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Gaithersburg, MD 20877, USA
    Hum Genet 127:91-9. 2010
  2. pmc Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels
    Hemang Parikh
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20877, USA
    Hum Genet 129:675-85. 2011
  3. pmc Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry
    Zhaoming Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Hum Genet 131:1173-85. 2012
  4. pmc An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer
    Jinping Jia
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Med Genomics 6:33. 2013
  5. pmc The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients
    Eydis Th Gudmundsdottir
    Department of Pathology, Landspitali University Hospital, Hringbraut, 101, Reykjavik, Iceland
    BMC Cancer 12:621. 2012
  6. pmc A resequence analysis of genomic loci on chromosomes 1q32.1, 5p15.33, and 13q22.1 associated with pancreatic cancer risk
    Hemang Parikh
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Pancreas 42:209-15. 2013
  7. pmc Lack of germline PALB2 mutations in melanoma-prone families with CDKN2A mutations and pancreatic cancer
    Xiaohong R Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA
    Fam Cancer 10:545-8. 2011
  8. pmc Assessing disease risk in genome-wide association studies using family history
    Arpita Ghosh
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Epidemiology 23:616-22. 2012
  9. pmc Detectable clonal mosaicism and its relationship to aging and cancer
    Kevin B Jacobs
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, Rockville, Maryland, USA
    Nat Genet 44:651-8. 2012
  10. pmc Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
    Joanne W Elena
    Division of Cancer Control and Population Science, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Cancer Causes Control 24:13-25. 2013

Detail Information

Publications12

  1. pmc A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33
    Hemang Parikh
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Gaithersburg, MD 20877, USA
    Hum Genet 127:91-9. 2010
    ....
  2. pmc Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels
    Hemang Parikh
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20877, USA
    Hum Genet 129:675-85. 2011
    ..12 ng/ml, 95% CI = 0.96-1.28) (P = 9.70 × 10(-5)). Together our results suggest that germline KLK3 variants could influence the diagnosis of nonaggressive prostate cancer by influencing the likelihood of biopsy...
  3. pmc Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry
    Zhaoming Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Hum Genet 131:1173-85. 2012
    ....
  4. pmc An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer
    Jinping Jia
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Med Genomics 6:33. 2013
    ..Pancreatic cancer is a highly lethal cancer with limited diagnostic and therapeutic modalities...
  5. pmc The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients
    Eydis Th Gudmundsdottir
    Department of Pathology, Landspitali University Hospital, Hringbraut, 101, Reykjavik, Iceland
    BMC Cancer 12:621. 2012
    ..The aim of the study was to examine the association of the risk allele with expression of TOX3 and LOC643714, and of mRNA levels and genotype with clinical and pathological characteristics...
  6. pmc A resequence analysis of genomic loci on chromosomes 1q32.1, 5p15.33, and 13q22.1 associated with pancreatic cancer risk
    Hemang Parikh
    Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Pancreas 42:209-15. 2013
    ..The objective of this study was to fine-map common pancreatic cancer susceptibility regions...
  7. pmc Lack of germline PALB2 mutations in melanoma-prone families with CDKN2A mutations and pancreatic cancer
    Xiaohong R Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA
    Fam Cancer 10:545-8. 2011
    ..The results suggested that PALB2 does not explain the relationship between CDKN2A, melanoma, and pancreatic cancer in these melanoma-prone families...
  8. pmc Assessing disease risk in genome-wide association studies using family history
    Arpita Ghosh
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Epidemiology 23:616-22. 2012
    ....
  9. pmc Detectable clonal mosaicism and its relationship to aging and cancer
    Kevin B Jacobs
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, Rockville, Maryland, USA
    Nat Genet 44:651-8. 2012
    ..4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases...
  10. pmc Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
    Joanne W Elena
    Division of Cancer Control and Population Science, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Cancer Causes Control 24:13-25. 2013
    ..This study prospectively examined the association between diabetes and the risk of pancreatic adenocarcinoma in pooled data from the NCI pancreatic cancer cohort consortium (PanScan)...
  11. pmc Large-scale exploration of gene-gene interactions in prostate cancer using a multistage genome-wide association study
    Julia Ciampa
    Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, USA
    Cancer Res 71:3287-95. 2011
    ..Overall, the interactions we have identified merit follow-up study, particularly the EPAS1 interaction, which has implications not only in prostate cancer but also in other epithelial cancers that are associated with the 8q24 locus...
  12. ncbi request reprint Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue
    Jianxin Shi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Nat Commun 5:3365. 2014
    ..Thus, inherited genetic variation may affect lung carcinogenesis by regulating the human methylome. ..