Research Topics
| Gelio AlvesSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators |
Detail Information
Publications
Calibrating E-values for MS2 database search methodsGelio Alves
National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20894, USA
Biol Direct 2:26. 2007..We also address the importance of using spectrum-specific statistics and possible improvement on the current calibration protocol. The spectra used for statistical (E-value) calibration are freely available upon request...
Detection of co-eluted peptides using database search methodsGelio Alves
National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD, 20894, USA
Biol Direct 3:27. 2008..OPEN PEER REVIEW: Reviewed by Vlad Petyuk (nominated by Arcady Mushegian), King Jordan and Shamil Sunyaev. For the full reviews, please go to the Reviewers' comments section...
RAId_DbS: mass-spectrometry based peptide identification web server with knowledge integrationGelio Alves
National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20894, USA
BMC Genomics 9:505. 2008..Integration of such information with peptide searches facilitates speedy, dynamic information retrieval that may significantly benefit clinical laboratory studies...
RAId_DbS: peptide identification using database searches with realistic statisticsGelio Alves
National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20894, USA
Biol Direct 2:25. 2007..The peptide identification performance and statistical accuracy of RAId_DbS are assessed and compared with several other search tools. The executables and data related to RAId_DbS are freely available upon request...
Enhancing peptide identification confidence by combining search methodsGelio Alves
National Center for Biotechnology Information, Library of Medicine, NIH, Bethesda, MD 20894, USA
J Proteome Res 7:3102-13. 2008..The data related to this study are freely available upon request...
RAId_aPS: MS/MS analysis with multiple scoring functions and spectrum-specific statisticsGelio Alves
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 5:e15438. 2010..The web link is http://www.ncbi.nlm.nih.gov/CBBresearch/Yu/raid_aps/index.html. Relevant binaries for Linux, Windows, and Mac OS X are available from the same page...
Assigning statistical significance to proteotypic peptides via database searchesGelio Alves
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
J Proteomics 74:199-211. 2011..The advantage of including proteotypic information is evidenced by its superior retrieval performance when compared to regular database searches...
Robust accurate identification of peptides (RAId): deciphering MS2 data using a structured library search with de novo based statisticsGelio Alves
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health Bethesda, MD 20894, USA
Bioinformatics 21:3726-32. 2005..Other important features of RAId include its potential in de novo sequencing alone and the ease of incorporating post-translational modifications...
Combining independent, weighted P-values: achieving computational stability by a systematic expansion with controllable accuracyGelio Alves
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 6:e22647. 2011..ncbi.nlm.nih.gov/CBBresearch/Yu/downloads/CoinedPValues.html...
