Carmen J Allegra

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The identification of thymidylate synthase peptide domains located in the interface region that bind thymidylate synthase mRNA
    Donna M Voeller
    Center for Cancer Research, Basic Research Laboratory, National Cancer Institute, National Institutes of Health, Building 37 Room 6050D, 37 Convent Drive MSC 4255, Bethesda, MD 20892, USA
    Biochem Biophys Res Commun 297:24-31. 2002
  2. ncbi request reprint Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
    Carmen J Allegra
    Medicine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 2440, USA
    J Clin Oncol 21:241-50. 2003
  3. ncbi request reprint Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer
    Carmen J Allegra
    National Cancer Institute, Bethesda, MD, USA
    J Clin Oncol 20:1735-43. 2002
  4. ncbi request reprint Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites
    Patrick G Johnston
    Cancer Research Centre, Department of Oncology, Queen s University Belfast, Belfast, Northern Ireland
    J Clin Oncol 21:815-9. 2003
  5. ncbi request reprint Thymidylate synthase expression in colon carcinomas with microsatellite instability
    Frank A Sinicrope
    Mayo Clinic and Mayo College of Medicine, Rochester, Minnesota 55905, USA
    Clin Cancer Res 12:2738-44. 2006
  6. ncbi request reprint Cytotoxins and cancer immunotherapy: the dance of the macabre?
    Carmen J Allegra
    J Natl Cancer Inst 97:1396-7. 2005
  7. ncbi request reprint Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study
    George P Kim
    National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Centers, Mayo Clinic, Jacksonville, FL 32224, USA
    J Clin Oncol 25:767-72. 2007
  8. ncbi request reprint Microsatellite instability in colon cancer
    Carmen J Allegra
    N Engl J Med 349:1774-6; author reply 1774-6. 2003
  9. ncbi request reprint Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling
    Pamela J Maxwell
    Department of Oncology, Cancer Research Centre, Queen s University Belfast, University Floor, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland
    Cancer Res 63:4602-6. 2003
  10. doi request reprint Don Quixote and the quest for personalized medicine
    Carmen J Allegra
    J Clin Oncol 26:2619-20. 2008

Collaborators

Detail Information

Publications10

  1. ncbi request reprint The identification of thymidylate synthase peptide domains located in the interface region that bind thymidylate synthase mRNA
    Donna M Voeller
    Center for Cancer Research, Basic Research Laboratory, National Cancer Institute, National Institutes of Health, Building 37 Room 6050D, 37 Convent Drive MSC 4255, Bethesda, MD 20892, USA
    Biochem Biophys Res Commun 297:24-31. 2002
    ..These data suggest that the identified highly conserved protein domains, which occur at the homodimeric interface of TS, represent potential participating sites for binding of TS protein to its mRNA...
  2. ncbi request reprint Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
    Carmen J Allegra
    Medicine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 2440, USA
    J Clin Oncol 21:241-50. 2003
    ..To define the value of thymidylate synthase (TS), Ki-67, and p53 as prognostic markers in patients with stage II and III colon carcinoma...
  3. ncbi request reprint Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer
    Carmen J Allegra
    National Cancer Institute, Bethesda, MD, USA
    J Clin Oncol 20:1735-43. 2002
    ..To evaluate the value of thymidylate synthase (TS), Ki-67, and p53 as prognostic markers in patients with Dukes' B2 and C colon carcinoma...
  4. ncbi request reprint Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites
    Patrick G Johnston
    Cancer Research Centre, Department of Oncology, Queen s University Belfast, Belfast, Northern Ireland
    J Clin Oncol 21:815-9. 2003
    ....
  5. ncbi request reprint Thymidylate synthase expression in colon carcinomas with microsatellite instability
    Frank A Sinicrope
    Mayo Clinic and Mayo College of Medicine, Rochester, Minnesota 55905, USA
    Clin Cancer Res 12:2738-44. 2006
    ..Given that thymidylate synthase (TS) is inhibited by 5-FU, we studied the relationship between MSI and TS expression, and the prognostic effect of these and other markers (i.e., p53 and 17p allelic imbalance)...
  6. ncbi request reprint Cytotoxins and cancer immunotherapy: the dance of the macabre?
    Carmen J Allegra
    J Natl Cancer Inst 97:1396-7. 2005
  7. ncbi request reprint Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study
    George P Kim
    National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Centers, Mayo Clinic, Jacksonville, FL 32224, USA
    J Clin Oncol 25:767-72. 2007
    ..The role of high-degree microsatellite instability (MSI-H) as a marker to predict benefit from adjuvant chemotherapy remains unclear...
  8. ncbi request reprint Microsatellite instability in colon cancer
    Carmen J Allegra
    N Engl J Med 349:1774-6; author reply 1774-6. 2003
  9. ncbi request reprint Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling
    Pamela J Maxwell
    Department of Oncology, Cancer Research Centre, Queen s University Belfast, University Floor, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland
    Cancer Res 63:4602-6. 2003
    ..These results demonstrate the potential of DNA microarrays to identify novel genes involved in mediating the response of tumor cells to chemotherapy...
  10. doi request reprint Don Quixote and the quest for personalized medicine
    Carmen J Allegra
    J Clin Oncol 26:2619-20. 2008