Research Topics
Genomes and GenesSpecies | D AlbanesSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancerDemetrius Albanes
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3044, Bethesda, MD 20892 7242, USA
J Natl Cancer Inst 101:1272-9. 2009..The mitogenic and growth-stimulatory effects of insulin-like growth factors appear to play a role in prostate carcinogenesis, yet any direct association of circulating insulin levels and risk of prostate cancer remains unclear...
Serum 25-hydroxy vitamin D and prostate cancer risk in a large nested case-control studyDemetrius Albanes
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, Bethesda, MD 20982, USA
Cancer Epidemiol Biomarkers Prev 20:1850-60. 2011..Vitamin D compounds inhibit prostate tumorigenesis experimentally, but epidemiologic data are inconsistent with respect to prostate cancer risk, with some studies suggesting nonsignificant positive associations...
Beta-carotene and lung cancer: a case studyD Albanes
Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892 7058, USA
Am J Clin Nutr 69:1345S-1350S. 1999....
Prevalence of disease-related DNA polymorphisms among participants in a large cancer prevention trialK Woodson
Division of Clinical Sciences, National Cancer Institute, Cancer Prevention Studies Branch, Bethesda, MD 20892 7058, USA
Eur J Cancer Prev 8:441-7. 1999..We present herein results from this survey and conclude that the ATBC study population in Finland is sufficiently heterogeneous to facilitate analysis of genetic polymorphisms and disease associations...
Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokersR Z Stolzenberg-Solomon
Cancer Prevention Studies Branch, Division of Clinical Science, National Cancer Institute, Bethesda, MD 20892, USA
Am J Epidemiol 153:680-7. 2001..10, 3.03; p-trend = 0.05). These results support the hypothesis that dietary folate intake is inversely associated with the risk of pancreatic cancer and confirm the risk associated with greater cigarette smoking...
Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokersR Z Stolzenberg-Solomon
Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD, USA
J Natl Cancer Inst 91:535-41. 1999..Whether biochemical indicators of methyl-group availability are associated with exocrine pancreatic cancer risk was the focus of this investigation...
Tea and coffee consumption and risk of colon and rectal cancer in middle-aged Finnish menT J Hartman
Divison of Clinical Science, National Cancer Institute, Bethesda, MD 20892, USA
Nutr Cancer 31:41-8. 1998..However, given the strength of the tea-colon cancer association and the significant gradient of risk we observed across level of intake, further epidemiologic research of this relationship in other populations seems warranted...
Variation in the promoter region of the myeloperoxidase gene is not directly related to lung cancer risk among male smokers in FinlandR R Misra
Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, 6006 Executive Boulevard, Suite 321, Bethesda, MD 20892 7058, USA
Cancer Lett 164:161-7. 2001..These findings contrast with those from previous studies that report decreased lung cancer risk among MPO variant individuals...
Influence of antioxidants and the CYP1A1 isoleucine to valine polymorphism on the smoking--lung cancer associationD Ratnasinghe
Division of Clinical Sciences, National Cancer Institute, NIH, Bethseda, MD, USA
Anticancer Res 21:1295-9. 2001....
Polymorphisms in glutathione-S-transferase genes (GST-M1, GST-T1 and GST-P1) and susceptibility to prostate cancer among male smokers of the ATBC cancer prevention studyLa Creis R Kidd
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, 6116 Executive Blvd, Suite 705, MSC 8314, Bethesda, MD 20892 7058, USA
Eur J Cancer Prev 12:317-20. 2003..Our observation of a relatively strong inverse association between the GST-M1-null genotype and prostate cancer risk needs to be confirmed in larger association studies...
Helicobacter pylori seropositivity as a risk factor for pancreatic cancerR Z Stolzenberg-Solomon
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics and Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892, USA
J Natl Cancer Inst 93:937-41. 2001....
Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort studyD S Michaud
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Br J Cancer 87:960-5. 2002..These findings suggest that fruit and vegetable intakes are not likely to be associated with bladder cancer risk. However, these results may not be generalisable to non-smokers...
Physical activity in relation to cancer of the colon and rectum in a cohort of male smokersL H Colbert
Division of Clinical Sciences, National Cancer Institute, NIH, Bethesda, Maryland 20892-7058, USA
Cancer Epidemiol Biomarkers Prev 10:265-8. 2001..36-1.37) and moderate/heavy occupational activity (RR, 0.50; CI, 0.26-0.97; P for trend, 0.04), and no association for leisure activity. These data provide evidence for a protective role of physical activity in colon and rectal cancer...
Relationships of serum androgens and estrogens to prostate cancer risk: results from a prospective study in FinlandJ F Dorgan
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
Cancer Epidemiol Biomarkers Prev 7:1069-74. 1998..These results do not support a strong relationship of serum androgens and estrogens with prostate cancer in smokers. Within-person variation in concentrations of some hormones may have contributed to the lack of significant associations...
The effect of beta-carotene supplementation on serum vitamin D metabolite concentrationsD M Freedman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 8:1115-6. 1999....
Hypomethylation of p53 in peripheral blood DNA is associated with the development of lung cancerK Woodson
Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20892-7058, USA
Cancer Epidemiol Biomarkers Prev 10:69-74. 2001..Our results indicate that hypomethylation status within exons 5-8 of p53 from peripheral lymphocyte DNA may be a relevant predictor of lung cancer among male smokers...
Insulin-like growth factors and risk of kidney cancer in menJ M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20852, USA
Br J Cancer 103:132-5. 2010..Insulin-like growth factor-I (IGF-I) has been shown to increase kidney growth, glomerular filtration rate, and renal function...
Association between serum alpha-tocopherol and serum androgens and estrogens in older menT J Hartman
Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892, USA
Nutr Cancer 35:10-5. 1999....
Insulin-like growth factors and liver cancer risk in male smokersJ M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20852, USA
Br J Cancer 103:1089-92. 2010..The liver is the primary source of circulating insulin-like growth factor (IGF)-I, yet the relation between IGFs and liver cancer is uncertain...
Dietary fat, fat subtypes, and breast cancer in postmenopausal women: a prospective cohort studyE Velie
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
J Natl Cancer Inst 92:833-9. 2000..To extend the prospective epidemiologic evidence on this question, we examined the association between adult dietary intake of fat, fat subtypes, and breast cancer in a large, prospective cohort of postmenopausal women...
Influence of vitamin D binding protein on the association between circulating vitamin D and risk of bladder cancerA M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, Suite 320, Rockville, MD, USA
Br J Cancer 107:1589-94. 2012..There is little research investigating the role of vitamin D binding protein (DBP) in the association between 25-hydroxyvitamin D (25(OH)D) and disease risk...
Glutathione peroxidase codon 198 polymorphism variant increases lung cancer riskD Ratnasinghe
Division of Clinical Sciences, National Cancer Institute, NIH, Bethesda, Maryland 20892 7058, USA
Cancer Res 60:6381-3. 2000..Due to its high prevalence, the hGPX1 variant may contribute significantly to lung cancer risk among Caucasians but not among ethnic Chinese who do not exhibit this polymorphism...
Height and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trialJ Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
Br J Cancer 101:522-5. 2009..The relationship between prostate cancer and height is uncertain...
Weight and body composition changes during and after adjuvant chemotherapy in women with breast cancerR J Freedman
Unit on Growth and Obesity, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 89:2248-53. 2004..They do, however, appear to undergo unfavorable changes in body composition...
No association between alcohol supplementation and autoantibodies to DNA damage in postmenopausal women in a controlled feeding studyS Mahabir
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
Eur J Cancer Prev 14:427-9. 2005..In future studies, a panel of biomarkers for DNA damage should be used...
Past body mass index and risk of mortality among womenS C Moore
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Obes (Lond) 32:730-9. 2008..Analysis of BMI from an earlier time period may minimize reverse causation without requiring exclusion of participants based on disease or smoking history...
Dietary and serum alpha-tocopherol, beta-carotene and retinol, and risk for colorectal cancer in male smokersN Malila
National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
Eur J Clin Nutr 56:615-21. 2002..To study the association between dietary and serum antioxidant vitamins and carotenoids and risk for colorectal cancer in male smokers...
Life-style factors and risk for abdominal aortic aneurysm in a cohort of Finnish male smokersM E Törnwall
Department of Nutrition, Kansanterveyslaitos, National Public Health Institute, Helsinki, Finland
Epidemiology 12:94-100. 2001..We conclude that classical risk factors for atherosclerotic diseases seem to be important in pathogenesis of large abdominal aortic aneurysms...
Intake of flavonols and flavones and risk of coronary heart disease in male smokersT Hirvonen
Department of Nutrition, National Public Health Institute, Helsinki, Finland
Epidemiology 12:62-7. 2001..89 (95% confidence interval = 0.71-1.11). Thus, intake of flavonols and flavones was inversely associated with nonfatal myocardial infarction, whereas there was a weaker association with coronary death...
Association of the B-vitamins pyridoxal 5'-phosphate (B(6)), B(12), and folate with lung cancer risk in older menT J Hartman
Department of Nutrition, The Pennsylvania State University, University Park, PA, USA
Am J Epidemiol 153:688-94. 2001..This is the first report from a prospectively conducted study to suggest a role for vitamin B(6) in lung cancer...
Effect of alpha-tocopherol and beta-carotene supplementation on the incidence of type 2 diabetesM Kataja-Tuomola
Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Mannerheimintie 166, 00300, Helsinki, Finland
Diabetologia 51:47-53. 2008..Only a few human studies have investigated the role of antioxidants in the pathogenesis of diabetes. This study aimed to examine whether alpha-tocopherol or beta-carotene affected the occurrence of type 2 diabetes...
Physical activity and the risk of pneumonia in male smokers administered vitamin E and beta-caroteneH Hemilä
Department of Public Health, University of Helsinki, Helsinki, Finland
Int J Sports Med 27:336-41. 2006..The finding that vitamin E reduced the risk of pneumonia in persons carrying out leisure-time exercise warrants further study...
A candidate gene approach to searching for low-penetrance breast and prostate cancer genesD J Hunter
Nat Rev Cancer 5:977-85. 2005....
Molecular epidemiologic studies within the Selenium and Vitamin E Cancer Prevention Trial (SELECT)A Hoque
Department of Clinical Cancer Prevention, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
Cancer Causes Control 12:627-33. 2001..CONCLUSION: SELECT offers an excellent opportunity to conduct molecular epidemiologic investigations to assess gene-environment interactions and their role in prostate, lung, and colon carcinogenesis...
Effects of long-term alpha-tocopherol supplementation on serum hormones in older menT J Hartman
Department of Nutrition, Pennsylvania State University, University Park, Pennsylvania, USA
Prostate 46:33-8. 2001....
SELECT: the next prostate cancer prevention trial. Selenum and Vitamin E Cancer Prevention TrialE A Klein
Section of Urologic Oncology, Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Urol 166:1311-5. 2001..CONCLUSIONS: SELECT is the second large-scale study of chemoprevention for prostate cancer. Enrollment in the study is planned to begin in 2001 with final results anticipated in 2013...
