D Albanes

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Genome-wide association study of circulating vitamin D levels
    Jiyoung Ahn
    Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, USA
    Hum Mol Genet 19:2739-45. 2010
  2. pmc Genome-wide association study identifies common variants associated with circulating vitamin E levels
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics and Core Genotyping Facility, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Hum Mol Genet 20:3876-83. 2011
  3. pmc Genome-wide association study of circulating retinol levels
    Alison M Mondul
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Hum Mol Genet 20:4724-31. 2011
  4. pmc Serum 25-hydroxy vitamin D and prostate cancer risk in a large nested case-control study
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, Bethesda, MD 20982, USA
    Cancer Epidemiol Biomarkers Prev 20:1850-60. 2011
  5. pmc Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3044, Bethesda, MD 20892 7242, USA
    J Natl Cancer Inst 101:1272-9. 2009
  6. ncbi request reprint Beta-carotene and lung cancer: a case study
    D Albanes
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892 7058, USA
    Am J Clin Nutr 69:1345S-1350S. 1999
  7. ncbi request reprint Prevalence of disease-related DNA polymorphisms among participants in a large cancer prevention trial
    K Woodson
    Division of Clinical Sciences, National Cancer Institute, Cancer Prevention Studies Branch, Bethesda, MD 20892 7058, USA
    Eur J Cancer Prev 8:441-7. 1999
  8. ncbi request reprint Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers
    R Z Stolzenberg-Solomon
    Cancer Prevention Studies Branch, Division of Clinical Science, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 153:680-7. 2001
  9. ncbi request reprint Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers
    R Z Stolzenberg-Solomon
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 91:535-41. 1999
  10. ncbi request reprint Variation in the promoter region of the myeloperoxidase gene is not directly related to lung cancer risk among male smokers in Finland
    R R Misra
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, 6006 Executive Boulevard, Suite 321, Bethesda, MD 20892 7058, USA
    Cancer Lett 164:161-7. 2001

Detail Information

Publications41

  1. pmc Genome-wide association study of circulating vitamin D levels
    Jiyoung Ahn
    Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, USA
    Hum Mol Genet 19:2739-45. 2010
    ..8x10(-49)), NADSYN1/DHCR7 (P=3.4x10(-9)) and CYP2R1 (P=2.9x10(-17)), but not C10orf88 (P=2.4x10(-5))...
  2. pmc Genome-wide association study identifies common variants associated with circulating vitamin E levels
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics and Core Genotyping Facility, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Hum Mol Genet 20:3876-83. 2011
    ..In one of the two male GWAS cohorts (n= 992), no SNPs were significantly associated with gamma-tocopherol concentrations after including data from the replication sample for 71 independent SNPs with P< 1 × 10(-4) identified...
  3. pmc Genome-wide association study of circulating retinol levels
    Alison M Mondul
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Hum Mol Genet 20:4724-31. 2011
    ..31× 10(-5)). Discovery of common genetic variants associated with serum retinol levels may provide further insight into the contribution of retinol and other vitamin A compounds to the development of cancer and other complex diseases...
  4. pmc Serum 25-hydroxy vitamin D and prostate cancer risk in a large nested case-control study
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, Bethesda, MD 20982, USA
    Cancer Epidemiol Biomarkers Prev 20:1850-60. 2011
    ..Vitamin D compounds inhibit prostate tumorigenesis experimentally, but epidemiologic data are inconsistent with respect to prostate cancer risk, with some studies suggesting nonsignificant positive associations...
  5. pmc Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3044, Bethesda, MD 20892 7242, USA
    J Natl Cancer Inst 101:1272-9. 2009
    ..The mitogenic and growth-stimulatory effects of insulin-like growth factors appear to play a role in prostate carcinogenesis, yet any direct association of circulating insulin levels and risk of prostate cancer remains unclear...
  6. ncbi request reprint Beta-carotene and lung cancer: a case study
    D Albanes
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892 7058, USA
    Am J Clin Nutr 69:1345S-1350S. 1999
    ....
  7. ncbi request reprint Prevalence of disease-related DNA polymorphisms among participants in a large cancer prevention trial
    K Woodson
    Division of Clinical Sciences, National Cancer Institute, Cancer Prevention Studies Branch, Bethesda, MD 20892 7058, USA
    Eur J Cancer Prev 8:441-7. 1999
    ..We present herein results from this survey and conclude that the ATBC study population in Finland is sufficiently heterogeneous to facilitate analysis of genetic polymorphisms and disease associations...
  8. ncbi request reprint Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers
    R Z Stolzenberg-Solomon
    Cancer Prevention Studies Branch, Division of Clinical Science, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 153:680-7. 2001
    ..10, 3.03; p-trend = 0.05). These results support the hypothesis that dietary folate intake is inversely associated with the risk of pancreatic cancer and confirm the risk associated with greater cigarette smoking...
  9. ncbi request reprint Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers
    R Z Stolzenberg-Solomon
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 91:535-41. 1999
    ..Whether biochemical indicators of methyl-group availability are associated with exocrine pancreatic cancer risk was the focus of this investigation...
  10. ncbi request reprint Variation in the promoter region of the myeloperoxidase gene is not directly related to lung cancer risk among male smokers in Finland
    R R Misra
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, 6006 Executive Boulevard, Suite 321, Bethesda, MD 20892 7058, USA
    Cancer Lett 164:161-7. 2001
    ..These findings contrast with those from previous studies that report decreased lung cancer risk among MPO variant individuals...
  11. ncbi request reprint Tea and coffee consumption and risk of colon and rectal cancer in middle-aged Finnish men
    T J Hartman
    Divison of Clinical Science, National Cancer Institute, Bethesda, MD 20892, USA
    Nutr Cancer 31:41-8. 1998
    ..However, given the strength of the tea-colon cancer association and the significant gradient of risk we observed across level of intake, further epidemiologic research of this relationship in other populations seems warranted...
  12. ncbi request reprint Helicobacter pylori seropositivity as a risk factor for pancreatic cancer
    R Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics and Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 93:937-41. 2001
    ....
  13. ncbi request reprint Influence of antioxidants and the CYP1A1 isoleucine to valine polymorphism on the smoking--lung cancer association
    D Ratnasinghe
    Division of Clinical Sciences, National Cancer Institute, NIH, Bethseda, MD, USA
    Anticancer Res 21:1295-9. 2001
    ....
  14. pmc Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study
    D S Michaud
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Br J Cancer 87:960-5. 2002
    ..These findings suggest that fruit and vegetable intakes are not likely to be associated with bladder cancer risk. However, these results may not be generalisable to non-smokers...
  15. ncbi request reprint Polymorphisms in glutathione-S-transferase genes (GST-M1, GST-T1 and GST-P1) and susceptibility to prostate cancer among male smokers of the ATBC cancer prevention study
    La Creis R Kidd
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, 6116 Executive Blvd, Suite 705, MSC 8314, Bethesda, MD 20892 7058, USA
    Eur J Cancer Prev 12:317-20. 2003
    ..Our observation of a relatively strong inverse association between the GST-M1-null genotype and prostate cancer risk needs to be confirmed in larger association studies...
  16. ncbi request reprint Relationships of serum androgens and estrogens to prostate cancer risk: results from a prospective study in Finland
    J F Dorgan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
    Cancer Epidemiol Biomarkers Prev 7:1069-74. 1998
    ..These results do not support a strong relationship of serum androgens and estrogens with prostate cancer in smokers. Within-person variation in concentrations of some hormones may have contributed to the lack of significant associations...
  17. ncbi request reprint Physical activity in relation to cancer of the colon and rectum in a cohort of male smokers
    L H Colbert
    Division of Clinical Sciences, National Cancer Institute, NIH, Bethesda, Maryland 20892-7058, USA
    Cancer Epidemiol Biomarkers Prev 10:265-8. 2001
    ..36-1.37) and moderate/heavy occupational activity (RR, 0.50; CI, 0.26-0.97; P for trend, 0.04), and no association for leisure activity. These data provide evidence for a protective role of physical activity in colon and rectal cancer...
  18. ncbi request reprint The effect of beta-carotene supplementation on serum vitamin D metabolite concentrations
    D M Freedman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 8:1115-6. 1999
    ....
  19. pmc Insulin-like growth factors and risk of kidney cancer in men
    J M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20852, USA
    Br J Cancer 103:132-5. 2010
    ..Insulin-like growth factor-I (IGF-I) has been shown to increase kidney growth, glomerular filtration rate, and renal function...
  20. ncbi request reprint Hypomethylation of p53 in peripheral blood DNA is associated with the development of lung cancer
    K Woodson
    Cancer Prevention Studies Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20892-7058, USA
    Cancer Epidemiol Biomarkers Prev 10:69-74. 2001
    ..Our results indicate that hypomethylation status within exons 5-8 of p53 from peripheral lymphocyte DNA may be a relevant predictor of lung cancer among male smokers...
  21. pmc The association of coffee intake with liver cancer incidence and chronic liver disease mortality in male smokers
    G Y Lai
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, 9609 Medical Center Drive, Room 2W136 MSC 9712, Bethesda, MD 20892, USA
    Br J Cancer 109:1344-51. 2013
    ..Yet, prospective studies in Western populations with lower HBV and HCV prevalence are sparse. Also, although preparation methods affect coffee constituents, it is unknown whether different methods affect disease associations...
  22. ncbi request reprint Association between serum alpha-tocopherol and serum androgens and estrogens in older men
    T J Hartman
    Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892, USA
    Nutr Cancer 35:10-5. 1999
    ....
  23. pmc Pigmentation-related phenotypes and risk of prostate cancer
    S J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Br J Cancer 109:747-50. 2013
    ..Pigmentation-related traits influence endogenous vitamin D synthesis and may alter risk of prostate cancer...
  24. ncbi request reprint Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk
    D Ratnasinghe
    Division of Clinical Sciences, National Cancer Institute, NIH, Bethesda, Maryland 20892 7058, USA
    Cancer Res 60:6381-3. 2000
    ..Due to its high prevalence, the hGPX1 variant may contribute significantly to lung cancer risk among Caucasians but not among ethnic Chinese who do not exhibit this polymorphism...
  25. ncbi request reprint Dietary fat, fat subtypes, and breast cancer in postmenopausal women: a prospective cohort study
    E Velie
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 92:833-9. 2000
    ..To extend the prospective epidemiologic evidence on this question, we examined the association between adult dietary intake of fat, fat subtypes, and breast cancer in a large, prospective cohort of postmenopausal women...
  26. pmc Insulin-like growth factors and liver cancer risk in male smokers
    J M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20852, USA
    Br J Cancer 103:1089-92. 2010
    ..The liver is the primary source of circulating insulin-like growth factor (IGF)-I, yet the relation between IGFs and liver cancer is uncertain...
  27. pmc Influence of vitamin D binding protein on the association between circulating vitamin D and risk of bladder cancer
    A M Mondul
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, Suite 320, Rockville, MD, USA
    Br J Cancer 107:1589-94. 2012
    ..There is little research investigating the role of vitamin D binding protein (DBP) in the association between 25-hydroxyvitamin D (25(OH)D) and disease risk...
  28. pmc Height and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    J Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
    Br J Cancer 101:522-5. 2009
    ..The relationship between prostate cancer and height is uncertain...
  29. ncbi request reprint Weight and body composition changes during and after adjuvant chemotherapy in women with breast cancer
    R J Freedman
    Unit on Growth and Obesity, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 89:2248-53. 2004
    ..They do, however, appear to undergo unfavorable changes in body composition...
  30. ncbi request reprint No association between alcohol supplementation and autoantibodies to DNA damage in postmenopausal women in a controlled feeding study
    S Mahabir
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Eur J Cancer Prev 14:427-9. 2005
    ..In future studies, a panel of biomarkers for DNA damage should be used...
  31. pmc Past body mass index and risk of mortality among women
    S C Moore
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Obes (Lond) 32:730-9. 2008
    ..Analysis of BMI from an earlier time period may minimize reverse causation without requiring exclusion of participants based on disease or smoking history...
  32. ncbi request reprint Molecular epidemiologic studies within the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
    A Hoque
    Department of Clinical Cancer Prevention, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
    Cancer Causes Control 12:627-33. 2001
    ..CONCLUSION: SELECT offers an excellent opportunity to conduct molecular epidemiologic investigations to assess gene-environment interactions and their role in prostate, lung, and colon carcinogenesis...
  33. ncbi request reprint Intake of flavonols and flavones and risk of coronary heart disease in male smokers
    T Hirvonen
    Department of Nutrition, National Public Health Institute, Helsinki, Finland
    Epidemiology 12:62-7. 2001
    ..89 (95% confidence interval = 0.71-1.11). Thus, intake of flavonols and flavones was inversely associated with nonfatal myocardial infarction, whereas there was a weaker association with coronary death...
  34. ncbi request reprint Life-style factors and risk for abdominal aortic aneurysm in a cohort of Finnish male smokers
    M E Törnwall
    Department of Nutrition, Kansanterveyslaitos, National Public Health Institute, Helsinki, Finland
    Epidemiology 12:94-100. 2001
    ..We conclude that classical risk factors for atherosclerotic diseases seem to be important in pathogenesis of large abdominal aortic aneurysms...
  35. ncbi request reprint Effects of long-term alpha-tocopherol supplementation on serum hormones in older men
    T J Hartman
    Department of Nutrition, Pennsylvania State University, University Park, Pennsylvania, USA
    Prostate 46:33-8. 2001
    ....
  36. ncbi request reprint Effect of alpha-tocopherol and beta-carotene supplementation on the incidence of type 2 diabetes
    M Kataja-Tuomola
    Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Mannerheimintie 166, 00300, Helsinki, Finland
    Diabetologia 51:47-53. 2008
    ..Only a few human studies have investigated the role of antioxidants in the pathogenesis of diabetes. This study aimed to examine whether alpha-tocopherol or beta-carotene affected the occurrence of type 2 diabetes...
  37. ncbi request reprint Physical activity and the risk of pneumonia in male smokers administered vitamin E and beta-carotene
    H Hemilä
    Department of Public Health, University of Helsinki, Helsinki, Finland
    Int J Sports Med 27:336-41. 2006
    ..The finding that vitamin E reduced the risk of pneumonia in persons carrying out leisure-time exercise warrants further study...
  38. ncbi request reprint A candidate gene approach to searching for low-penetrance breast and prostate cancer genes
    D J Hunter
    Nat Rev Cancer 5:977-85. 2005
    ....
  39. ncbi request reprint Association of the B-vitamins pyridoxal 5'-phosphate (B(6)), B(12), and folate with lung cancer risk in older men
    T J Hartman
    Department of Nutrition, The Pennsylvania State University, University Park, PA, USA
    Am J Epidemiol 153:688-94. 2001
    ..This is the first report from a prospectively conducted study to suggest a role for vitamin B(6) in lung cancer...
  40. ncbi request reprint Dietary and serum alpha-tocopherol, beta-carotene and retinol, and risk for colorectal cancer in male smokers
    N Malila
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Eur J Clin Nutr 56:615-21. 2002
    ..To study the association between dietary and serum antioxidant vitamins and carotenoids and risk for colorectal cancer in male smokers...
  41. ncbi request reprint SELECT: the next prostate cancer prevention trial. Selenum and Vitamin E Cancer Prevention Trial
    E A Klein
    Section of Urologic Oncology, Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Urol 166:1311-5. 2001
    ..CONCLUSIONS: SELECT is the second large-scale study of chemoprevention for prostate cancer. Enrollment in the study is planned to begin in 2001 with final results anticipated in 2013...