Mayada Akil

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Catechol-O-methyltransferase genotype and dopamine regulation in the human brain
    Mayada Akil
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 23:2008-13. 2003
  2. ncbi Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia
    Subroto Ghose
    Clinical Brain Disorders Branch, NIMH, NIH, Bethesda, Maryland, USA
    Int J Neurosci 118:1609-27. 2008
  3. ncbi Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes
    William R Perlman
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD 20892-1384, USA
    J Psychiatry Neurosci 29:287-93. 2004
  4. ncbi Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia
    Michael F Egan
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health NIH DHHS, Building 10, Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 101:12604-9. 2004
  5. ncbi Reliability of psychiatric diagnosis in postmortem research
    Amy Deep-Soboslay
    Section on Neuropathology, Clinical Brain Disorders Branch, National Institute of Mental Health/NIH, 10 Center Drive, Bethesda, MD 20892, USA
    Biol Psychiatry 57:96-101. 2005

Collaborators

Detail Information

Publications5

  1. ncbi Catechol-O-methyltransferase genotype and dopamine regulation in the human brain
    Mayada Akil
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 23:2008-13. 2003
    ..This indicates that COMT genotype is a heritable aspect of dopamine regulation and it further explicates the mechanism by which the COMT valine allele increases susceptibility for psychosis...
  2. ncbi Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia
    Subroto Ghose
    Clinical Brain Disorders Branch, NIMH, NIH, Bethesda, Maryland, USA
    Int J Neurosci 118:1609-27. 2008
    ..The expression of mGluR2, 3 in DA cells provide a mechanism for glutamate to modulate dopamine release in the human brain and this species-specific difference may be critical to understanding rodent models in schizophrenia...
  3. ncbi Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes
    William R Perlman
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD 20892-1384, USA
    J Psychiatry Neurosci 29:287-93. 2004
    ....
  4. ncbi Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia
    Michael F Egan
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health NIH DHHS, Building 10, Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 101:12604-9. 2004
    ..These convergent data point to a specific molecular pathway by which GRM3 genotype alters glutamate neurotransmission, prefrontal and hippocampal physiology and cognition, and thereby increased risk for schizophrenia...
  5. ncbi Reliability of psychiatric diagnosis in postmortem research
    Amy Deep-Soboslay
    Section on Neuropathology, Clinical Brain Disorders Branch, National Institute of Mental Health/NIH, 10 Center Drive, Bethesda, MD 20892, USA
    Biol Psychiatry 57:96-101. 2005
    ....