Research Topics
Genomes and Genes
| Jiyoung AhnSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
No association between serum insulin-like growth factor (IGF)-I, IGF-binding protein-3, and lung cancer riskJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS-3044, 9000 Rockville Pike, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 15:2010-2. 2006
Association between manganese superoxide dismutase promoter gene polymorphism and breast cancer survivalRobert C G Martin
Division of Surgical Oncology, Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA
Breast Cancer Res 8:R45. 2006..The aim of our study was to investigate possible associations of the -102 C>T polymorphism with overall and relapse-free breast cancer survival in a hospital-based case-only study...
Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trialJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 16:2623-30. 2007..Furthermore, we found no relationship between calcium intake and circulating vitamin D...
Adiposity, adult weight change, and postmenopausal breast cancer riskJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS, 6120 Executive Blvd, Bethesda, MD 20892, USA
Arch Intern Med 167:2091-102. 2007..Obesity is a risk factor for postmenopausal breast cancer, but the role of the timing and amount of adult weight change in breast cancer risk is unclear...
Serum vitamin D concentration and prostate cancer risk: a nested case-control studyJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892, USA
J Natl Cancer Inst 100:796-804. 2008....
Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer riskJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Carcinogenesis 27:1876-82. 2006..These data indicate that GSTA1 genotypes related to reduced GSTA1 expression are associated with increased breast cancer primarily among women with lower consumption of cruciferous vegetables and among current smokers...
Vitamin D-related genes, serum vitamin D concentrations and prostate cancer riskJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Carcinogenesis 30:769-76. 2009..Results from the most comprehensive evaluation of serum vitamin D and its related genes to date suggest that tag SNPS in the 3' UTR of VDR may be associated with risk of prostate cancer in men with low vitamin D status...
Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer riskYulin Li
Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Carcinogenesis 30:777-84. 2009..77, 95% CI = 1.05-2.99, P-interaction = 0.006). Our results support the hypothesis that there are joint effects of endogenous and exogenous antioxidants...
Polymorphisms in genes related to oxidative stress (CAT, MnSOD, MPO, and eNOS) and acute toxicities from radiation therapy following lumpectomy for breast cancerJiyoung Ahn
Division of Cancer Prevention and Population Science, Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
Clin Cancer Res 12:7063-70. 2006....
Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement useJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Am J Epidemiol 162:943-52. 2005..CC genotypes were prevalent in approximately 64% of controls; thus, the preventive potential for fruit consumption has widespread implications...
Genetic variability in iron-related oxidative stress pathways (Nrf2, NQ01, NOS3, and HO-1), iron intake, and risk of postmenopausal breast cancerChi Chen Hong
Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Cancer Epidemiol Biomarkers Prev 16:1784-94. 2007....
Family history of prostate cancer and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) StudyJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
Int J Cancer 123:1154-9. 2008..Supplementation with vitamin E or beta-carotene did not modify the family history-prostate cancer association. This study provides additional evidence that family history is a significant risk factor for prostate cancer...
Adipokine genes and prostate cancer riskSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Cancer 124:869-76. 2009..05). Polymorphisms in the IL6, LEPR, TNF and ADIPOQ genes were not associated with prostate cancer. Allelic variants in the LEP gene are related to prostate cancer risk, supporting a role for leptin in prostate carcinogenesis...
Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer riskJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, New York, USA
Cancer Res 64:7634-9. 2004....
No association between glutathione peroxidase Pro198Leu polymorphism and breast cancer riskJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Cancer Epidemiol Biomarkers Prev 14:2459-61. 2005
HNF1B and JAZF1 genes, diabetes, and prostate cancer riskVictoria L Stevens
Department of Epidemiology, American Cancer Society, Atlanta, Georgia 30303 1002, USA
Prostate 70:601-7. 2010..Epidemiologic studies have shown that men with type II diabetes have a lower risk of prostate cancer than non-diabetic men. Recently, common variants in two genes, HNF1B and JAZF1, were found to be associated with both of these diseases...
Age-specific physical activity and prostate cancer risk among white men and black menSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Cancer 115:5060-70. 2009..The authors investigated physical activity, including activity during different age periods and of various intensities, in relation to prostate cancer incidence among white men and black men...
Diabetes mellitus and prostate cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening TrialMichael F Leitzmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
Cancer Causes Control 19:1267-76. 2008....
PAH-DNA adducts, cigarette smoking, GST polymorphisms, and breast cancer riskKathleen M McCarty
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Environ Health Perspect 117:552-8. 2009..Few breast cancer studies have investigated the joint effects of multiple GSTs and a PAH biomarker...
Prediagnostic total and high-density lipoprotein cholesterol and risk of cancerJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 18:2814-21. 2009..We examined the relationship between serum total and HDL cholesterol and risk of overall and site-specific cancers among 29,093 men in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort...
Associations between catalase phenotype and genotype: modification by epidemiologic factorsJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Cancer Epidemiol Biomarkers Prev 15:1217-22. 2006..Associations between genotype and phenotype were modified by dietary factors, illustrating the biochemical complexity of studies of genetic polymorphisms and disease risk...
Physical activity in relation to total, advanced, and fatal prostate cancerSteven C Moore
Division of Cancer Epidemiology, National Cancer Institute, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 17:2458-66. 2008..96; 95% CI, 0.67-1.36; P(trend) = 0.99). Neither vigorous exercise at baseline nor exercise during adolescence was related to risk of total, advanced, or fatal prostate cancer in this large prospective cohort...
Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3)Jiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Hum Mol Genet 18:3749-57. 2009..8%, P = 1.82 x 10(-6)). Genetic variation in genes in the sex steroid hormone pathway is associated with differences in circulating SHBG and sex steroid hormones...
Relationships between polymorphisms in NOS3 and MPO genes, cigarette smoking and risk of post-menopausal breast cancerJun Yang
Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Carcinogenesis 28:1247-53. 2007....
Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancerChristine B Ambrosone
Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Cancer Res 65:1105-11. 2005..33; 95% confidence interval, 0.13-0.80; P = 0.01). These data indicate that gene variants that impact oxidative stress modify prognosis after treatment for breast cancer...
Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patientsSusan A Nowell
Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Breast Cancer Res Treat 91:249-58. 2005..These studies indicate that genetic variation in Phase II conjugating enzymes can influence the efficacy of tamoxifen therapy for breast cancer...
A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33Hemang Parikh
Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Gaithersburg, MD 20877, USA
Hum Genet 127:91-9. 2010....
Gene-nutrient interactions in cancer etiologySusan A Nowell
Department of Epidemiology, Roswell Park Cancer Institute, Elm Street, Buffalo, NY 14263, USA
Nutr Rev 62:427-38. 2004..The role of consumption of fruits and vegetables, as well as the role of genetic variants in oxidative stress genes, in the risk of breast cancer are also discussed...
Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer: a case-series studyChristine B Ambrosone
Department of Epidemiology, Division of Cancer Prevention and Population Science, Roswell Park Cancer Institute, Buffalo, New York, USA
Breast Cancer Res 8:R40. 2006..We hypothesized that polymorphisms encoding reduced or absent activity in the GSTs might result in greater risk for radiation-associated toxicity...
Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancerNeal D Freedman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
Carcinogenesis 30:71-7. 2009..These findings should be interpreted cautiously until replicated in other studies...
Polymorphisms in oxidative stress genes, physical activity, and breast cancer riskLauren E McCullough
Department of Epidemiology, University of North Carolina, CB 7435, McGavran Greenberg Hall, Chapel Hill, NC 27599 7435, USA
Cancer Causes Control 23:1949-58. 2012..Given the paradoxical effects of physical activity, the oxidative stress pathway is of interest. Genetic variation in CAT or antioxidant-related polymorphisms may mediate the physical activity-breast cancer association...
Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control studyStephanie J Weinstein
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Servies, Bethesda, Maryland, United States of America
PLoS ONE 7:e40204. 2012..Many studies suggest protective effects among smokers and for aggressive prostate cancer, however...
Alcohol consumption and fatty acid intakes in the 2001-2002 National Health and Nutrition Examination SurveySoo Yeon Kim
Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892 9410, USA
Alcohol Clin Exp Res 31:1407-14. 2007..Alcohol consumption has the potential to affect dietary intakes of nutrients; however, little is known about fatty acid intakes among alcohol consumers in the U.S. population...
