Daniel W Wesson

Summary

Affiliation: Nathan Kline Institute
Country: USA

Publications

  1. pmc Why sniff fast? The relationship between sniff frequency, odor discrimination, and receptor neuron activation in the rat
    Daniel W Wesson
    Department of Biology, Boston University, Boston, MA, USA
    J Neurophysiol 101:1089-102. 2009
  2. pmc Olfactory dysfunction correlates with amyloid-beta burden in an Alzheimer's disease mouse model
    Daniel W Wesson
    Emotional Brain Institute and Center for Dementia Research, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 30:505-14. 2010
  3. pmc Smelling sounds: olfactory-auditory sensory convergence in the olfactory tubercle
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 30:3013-21. 2010
  4. pmc Respiratory and sniffing behaviors throughout adulthood and aging in mice
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Behav Brain Res 223:99-106. 2011
  5. pmc Sniffing out the contributions of the olfactory tubercle to the sense of smell: hedonics, sensory integration, and more?
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Neurosci Biobehav Rev 35:655-68. 2011
  6. pmc Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Behav Brain Res 216:408-13. 2011
  7. pmc Mechanisms of neural and behavioral dysfunction in Alzheimer's disease
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, New York University School of Medicine, Orangeburg, NY 10962, USA
    Mol Neurobiol 43:163-79. 2011
  8. pmc Temporal structure of receptor neuron input to the olfactory bulb imaged in behaving rats
    Ryan M Carey
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    J Neurophysiol 101:1073-88. 2009
  9. ncbi Sniffing controls an adaptive filter of sensory input to the olfactory bulb
    Justus V Verhagen
    Department of Biology, Boston University, 24 Cummington Street, Boston, Massachusetts 02215, USA
    Nat Neurosci 10:631-9. 2007
  10. pmc Optical dissection of odor information processing in vivo using GCaMPs expressed in specified cell types of the olfactory bulb
    Matt Wachowiak
    Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, UT 84132, USA
    J Neurosci 33:5285-300. 2013

Detail Information

Publications20

  1. pmc Why sniff fast? The relationship between sniff frequency, odor discrimination, and receptor neuron activation in the rat
    Daniel W Wesson
    Department of Biology, Boston University, Boston, MA, USA
    J Neurophysiol 101:1089-102. 2009
    ....
  2. pmc Olfactory dysfunction correlates with amyloid-beta burden in an Alzheimer's disease mouse model
    Daniel W Wesson
    Emotional Brain Institute and Center for Dementia Research, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 30:505-14. 2010
    ..Furthermore, these results present the odor cross-habituation test as a powerful behavioral assay, which reflects Abeta deposition and thus may serve to monitor the efficacy of therapies aimed at reducing Abeta...
  3. pmc Smelling sounds: olfactory-auditory sensory convergence in the olfactory tubercle
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 30:3013-21. 2010
    ..Thus, the tubercle presents itself as a source for direct multimodal convergence within an early stage of odor processing and may serve as a seat for psychophysical interactions between smells and sounds...
  4. pmc Respiratory and sniffing behaviors throughout adulthood and aging in mice
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Behav Brain Res 223:99-106. 2011
    ..These results show that odor-orienting responses are minimally impacted throughout aging in mice, and suggest that the olfactomotor network is mostly spared of insults due to aging...
  5. pmc Sniffing out the contributions of the olfactory tubercle to the sense of smell: hedonics, sensory integration, and more?
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Neurosci Biobehav Rev 35:655-68. 2011
    ..Together, the information within this review highlights an understudied yet potentially critical component in central odor processing...
  6. pmc Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Behav Brain Res 216:408-13. 2011
    ..These results suggest that the APP gene plays a role in affiliative behaviors and are discussed in relation to disorders characteristic of mutations in the APP gene and in affective dysfunction, including Alzheimer's disease...
  7. pmc Mechanisms of neural and behavioral dysfunction in Alzheimer's disease
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, New York University School of Medicine, Orangeburg, NY 10962, USA
    Mol Neurobiol 43:163-79. 2011
    ....
  8. pmc Temporal structure of receptor neuron input to the olfactory bulb imaged in behaving rats
    Ryan M Carey
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    J Neurophysiol 101:1073-88. 2009
    ....
  9. ncbi Sniffing controls an adaptive filter of sensory input to the olfactory bulb
    Justus V Verhagen
    Department of Biology, Boston University, 24 Cummington Street, Boston, Massachusetts 02215, USA
    Nat Neurosci 10:631-9. 2007
    ..Thus, sniffing controls an adaptive filter for detecting changes in the odor landscape. These data suggest an unexpected functional role for sniffing and show that sensory codes can be transformed by sampling behavior alone...
  10. pmc Optical dissection of odor information processing in vivo using GCaMPs expressed in specified cell types of the olfactory bulb
    Matt Wachowiak
    Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, UT 84132, USA
    J Neurosci 33:5285-300. 2013
    ..These results suggest multiple circuit elements with distinct roles in transforming odor representations in the OB and provide a framework for further study of early olfactory processing using optical and genetic tools...
  11. pmc Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model
    Jose Morales-Corraliza
    Center for Dementia Research, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Neurobiol Aging 34:137-45. 2013
    ....
  12. pmc Sniffing behavior of mice during performance in odor-guided tasks
    Daniel W Wesson
    Department of Biology, Boston University, Boston, MA 02215, USA
    Chem Senses 33:581-96. 2008
    ..These results show that mouse sniffing behavior is highly dynamic, varies with behavioral context, and is strongly modulated by olfactory as well as nonolfactory events...
  13. pmc Rapid encoding and perception of novel odors in the rat
    Daniel W Wesson
    Department of Biology, Boston University, Boston, Massachusetts, United States of America
    PLoS Biol 6:e82. 2008
    ..These results suggest a coding strategy in which the earliest-activated glomeruli play a major role in the initial perception of odor quality, and place constraints on coding and processing schemes based on simple changes in spike rate...
  14. pmc Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 31:15962-71. 2011
    ....
  15. doi Low-level mechanisms for processing odor information in the behaving animal
    Matt Wachowiak
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    Ann N Y Acad Sci 1170:286-92. 2009
    ..Thus, "high order" processing can occur even before sensory neurons transmit information to the brain...
  16. pmc Sexually dimorphic enhancement by estradiol of male urinary odor detection thresholds in mice
    Krystina G Sorwell
    Department of Biology, Boston University, Boston, MA 02215, USA
    Behav Neurosci 122:788-93. 2008
    ..Thus, estradiol enhanced detection thresholds for male urine in a sex-specific manner, and this enhanced sensitivity in females was correlated with altered odor-sampling behavior...
  17. pmc Chronic anti-murine Aβ immunization preserves odor guided behaviors in an Alzheimer's β-amyloidosis model
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Behav Brain Res 237:96-102. 2013
    ..Further, these results provide mechanistic insights into olfactory dysfunction as a biomarker for AD by yielding evidence that focal reductions of Aβ may be sufficient to preserve olfaction...
  18. ncbi Stacking anabolic androgenic steroids (AAS) during puberty in rats: a neuroendocrine and behavioral assessment
    Daniel W Wesson
    The University of Texas at San Antonio, Department of Biology, 6900 North Loop 1604 West, San Antonio, TX 78249, USA
    Pharmacol Biochem Behav 83:410-9. 2006
    ..The results indicate that stacking AAS influences the effects of individual AAS on behavioral and endocrine measures, and levels of androgen receptor occupation are not directly correlated with AAS effects on behavior...
  19. pmc Enhanced urinary odor discrimination in female aromatase knockout (ArKO) mice
    Daniel W Wesson
    Department of Biology, Boston University, Boston, MA 02215, USA
    Horm Behav 49:580-6. 2006
    ....
  20. pmc Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis
    Dun Sheng Yang
    Nathan Kline Institute, Orangeburg, NY, USA
    Autophagy 7:788-9. 2011
    ..Our findings underscore the pathogenic significance of autophagic-lysosomal dysfunction in AD and demonstrate the value of reversing this dysfunction as an innovative therapeautic strategy for AD...