Seymour Levine

Summary

Affiliation: Nathan Kline Institute
Country: USA

Publications

  1. ncbi request reprint A model for perinephric fluid accumulation in uremic rats with toxic nephrosis
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Toxicol Lett 146:9-15. 2003
  2. ncbi request reprint Acute uremia produced in rats by nephrotoxic chemicals is alleviated by protein deficient diet
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Ren Fail 25:517-23. 2003
  3. ncbi request reprint Choroidal bodies: a new structure in the fourth ventricular choroid plexus of the rat and mouse
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Brain Res 981:210-2. 2003
  4. ncbi request reprint Hydropic degeneration of the anterior pituitary gland (adenohypophysis) in uremic rats
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Toxicol Lett 147:121-6. 2004
  5. ncbi request reprint Metallic tin is an adjuvant for anaphylaxis in rats
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Trace Elem Res 98:275-7. 2004
  6. ncbi request reprint Pyridoxine (vitamin B6) toxicity: enhancement by uremia in rats
    S Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Food Chem Toxicol 40:1449-51. 2002
  7. ncbi request reprint Acute uremia in rats: feeding sucrose overnight is preferable to starvation
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Ren Fail 24:127-31. 2002
  8. ncbi request reprint Proliferation of glial cells induced by lithium in the neural lobe of the rat pituitary is enhanced by dehydration
    S Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Cell Prolif 35:167-72. 2002
  9. ncbi request reprint Pyridoxine (vitamin B6) neurotoxicity: enhancement by protein-deficient diet
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Appl Toxicol 24:497-500. 2004
  10. ncbi request reprint Lithium increases body weight of rats: relation to thymolysis
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Prog Neuropsychopharmacol Biol Psychiatry 30:155-8. 2006

Collaborators

Detail Information

Publications31

  1. ncbi request reprint A model for perinephric fluid accumulation in uremic rats with toxic nephrosis
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Toxicol Lett 146:9-15. 2003
    ..These experiments provide a model for perinephric (perirenal) fluid accumulation in certain human diseases and in certain intoxications of grazing animals...
  2. ncbi request reprint Acute uremia produced in rats by nephrotoxic chemicals is alleviated by protein deficient diet
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Ren Fail 25:517-23. 2003
    ..Acute uremia produced by nephrotoxic chemicals may be useful for further studies of the role of nutrition in uremia, while avoiding the surgical procedures and prolonged observations required for the "remnant kidney" models...
  3. ncbi request reprint Choroidal bodies: a new structure in the fourth ventricular choroid plexus of the rat and mouse
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Brain Res 981:210-2. 2003
    ..The function, if any, of the choroidal bodies is unknown. They were present in all rats that were studied by serial sections...
  4. ncbi request reprint Hydropic degeneration of the anterior pituitary gland (adenohypophysis) in uremic rats
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Toxicol Lett 147:121-6. 2004
    ..Morphologic lesions of the anterior pituitary related to hyponatremia and uremia have not been described previously...
  5. ncbi request reprint Metallic tin is an adjuvant for anaphylaxis in rats
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Trace Elem Res 98:275-7. 2004
    ..The new data support the notion that metallic tin causes polyclonal B-cell activation with proliferation of plasma cells...
  6. ncbi request reprint Pyridoxine (vitamin B6) toxicity: enhancement by uremia in rats
    S Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Food Chem Toxicol 40:1449-51. 2002
    ..These results suggest a need for caution in prescribing pyridoxine to uremic patients who will probably take the vitamin daily for many years...
  7. ncbi request reprint Acute uremia in rats: feeding sucrose overnight is preferable to starvation
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Ren Fail 24:127-31. 2002
    ..Sucrose feeding resulted in lower serum urea values and less loss of liver weight. Therefore, feeding sucrose overnight is preferable to starvation in uremic rats, as in normal rats...
  8. ncbi request reprint Proliferation of glial cells induced by lithium in the neural lobe of the rat pituitary is enhanced by dehydration
    S Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Cell Prolif 35:167-72. 2002
    ..This model of cell proliferation is of interest because the mitotic activity is related to a physiological attempt to maintain homeostasis rather than a response to injury or the development of neoplasia...
  9. ncbi request reprint Pyridoxine (vitamin B6) neurotoxicity: enhancement by protein-deficient diet
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Appl Toxicol 24:497-500. 2004
    ..Neither a protein-deficient diet nor bilateral nephrectomy changed the results with the vitamers...
  10. ncbi request reprint Lithium increases body weight of rats: relation to thymolysis
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Prog Neuropsychopharmacol Biol Psychiatry 30:155-8. 2006
    ..Our data suggest that lithium acts like nonspecific stress to increase weight gain as a consequence of elevated glucocorticoids, manifested in our experiments by thymolysis. This mechanism has not been proposed previously...
  11. ncbi request reprint A procedure for inducing sustained hyperlipemia in rats by administration of a surfactant
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    J Pharmacol Toxicol Methods 55:224-6. 2007
    ..These results make it possible to extend the use of tyloxapol into chronic studies of hyperlipemia and vascular disease...
  12. ncbi request reprint Lithium increases gastrointestinal tract weight of male or female rats but it increases body weight only in females
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Prog Neuropsychopharmacol Biol Psychiatry 32:29-33. 2008
    ..Lithium treatment of male rats also increased GI tract weight, but lithium did not increase their overall body weight because of loss of weight at other sites...
  13. doi request reprint Different inflammatory reactions to vitamin D3 among the lateral, third and fourth ventricular choroid plexuses of the rat
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Exp Mol Pathol 85:117-21. 2008
    ..These findings were compared to the scanty data from the literature on differences among the plexuses...
  14. pmc Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease
    Seymour Levine
    Center for Dementia Research, Nathan S Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Exp Mol Pathol 86:18-22. 2009
    ..The occurrence of lymphomas in mouse DS models is of interest in relation to the increased incidence of malignant conditions in human DS...
  15. pmc Mitotic figures in the median eminence of the hypothalamus
    Seymour Levine
    Center for Dementia Research, Nathan Kline Institute, NYU Langone Medical Center, Orangeburg, NY 10962, USA
    Neurochem Res 35:1743-6. 2010
    ..Thus, the present results suggest that the tanycyte layer may contain pituicytes, indicating that the hypothalamus possesses specialized cells for modulating neurosecretion in response to osmotic challenges...
  16. ncbi request reprint A method for peripheral chromatolysis in neurons of trigeminal and dorsal root ganglia, produced in rats by lithium
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    J Neurosci Methods 132:1-7. 2004
    ..This method may be useful for elucidating the intraneuronal mechanisms that control the location and structure of the Nissl bodies...
  17. pmc Vacuolar pathology in the median eminence of the hypothalamus after hyponatremia
    Seymour Levine
    Center for Dementia Research, Nathan Kline Institute, Orangeburg, New York 10962, USA
    J Neuropathol Exp Neurol 70:151-6. 2011
    ..This study indicates that the median eminence is a potentially vulnerable site in human hyponatremic conditions that should be evaluated further in relevant animal models...
  18. ncbi request reprint Malnutrition interferes with the unique lymphadenopathy induced in Lewis rats by metallic tin
    Seymour Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Trace Elem Res 85:71-6. 2002
    ..A high level of protein in the diet (50%) did not augment the effect of metallic tin powder beyond that achieved by a level usually considered adequate (20%)...
  19. ncbi request reprint Are urea and creatinine uremic toxins in the rat?
    S Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Ren Fail 23:53-9. 2001
    ..These data indicate that urea and creatinine are toxic in the acutely uremic rat. Hypertonicity of the serum may contribute to the toxicity of urea. Additional mechanisms of toxicity and additional toxins are not excluded...
  20. ncbi request reprint Effects of coprophagy on serum urea and the weight of the gastrointestinal tract of fed or fasted rats
    S Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Lab Anim 33:265-8. 1999
    ..Therefore, precautions against coprophagy, or their absence, should be specified in all experimental protocols and reports...
  21. ncbi request reprint Peritoneal toxicity of water: a model of chronic peritonitis caused by osmotic dysequilibrium in rats
    S Levine
    Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg, New York 10962, USA
    J Appl Toxicol 21:303-6. 2001
    ..Injection of water may be a useful method for investigating the role, if any, of mast cells and/or mesothelial cells in the toxic effects of osmotic dysequilibrium...
  22. ncbi request reprint Prevention of chronic peritonitis caused by osmotic dysequilibrium in rats
    S Levine
    Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Inflamm Res 50:500-2. 2001
    ..CONCLUSIONS: This study adds the peritoneum to the list of tissues in which adaptation to an injury can be accomplished by pretreatment with the same injurious agent, albeit in a less noxious form...
  23. ncbi request reprint Fluorinated anesthetics differ in toxic effects on peritoneum and subjacent tissues
    S Levine
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Appl Toxicol 18:79-80. 1998
    ..Intraperitoneal injection of fluorinated anesthetics produced anesthesia in rats. This was followed by toxic effects on peritoneal organs and surfaces, except for sevoflurane, which did not produce any lesions...
  24. ncbi request reprint Amiloride reduces stroke and renalinjury in stroke-prone hypertensive rats
    Reza Sepehrdad
    Department of Pharmacology, New York Medical College, Valhalla 10595, USA
    Am J Hypertens 16:312-8. 2003
    ..Presently, we examined whether amiloride, an epithelial sodium channel blocker, would also protect against pathology in these rats...
  25. pmc Dual circuitry for odor-shock conditioning during infancy: corticosterone switches between fear and attraction via amygdala
    Stephanie Moriceau
    Department of Zoology, University of Oklahoma, Norman, Oklahoma 73019, USA
    J Neurosci 26:6737-48. 2006
    ..Because maternal stimulation of pups modulates the pups' endogenous corticosterone, this suggests maternal care quality may alter sensitive-period duration...
  26. ncbi request reprint Hypothalamic-pituitary-adrenal axis response to sustained stress after major burn injury in children
    Tina L Palmieri
    Shriners Hospital for Children Northern California, University of California, Sacramento, California 95817, USA
    J Burn Care Res 27:742-8. 2006
    ..Random total serum cortisol measurements overestimate adrenal dysfunction; thus, ACTH stimulation testing should be used to assess adrenal function before the administration of exogenous steroids...
  27. ncbi request reprint Circadian rhythm of corticosterone secretion in the neonatal rabbit
    Maria J Rovirosa
    Lab Biologia de la Reproduccion, IIB, Universidad Veracruzana, A P 114, Xalapa 91000, Ver, Mexico
    Brain Res Dev Brain Res 158:92-6. 2005
    ..Unlike rodents, rabbit pups show a circadian secretion of CORT synchronized to the scheduled nursing bout...
  28. pmc Hormonal and metabolic rhythms associated with the daily scheduled nursing in rabbit pups
    Elvira Morgado
    Lab Biol de la Reproducción, IIB, Universidad Veracruzana, AP 114, Xalapa 91000, Veracruz, Mexico
    Am J Physiol Regul Integr Comp Physiol 295:R690-5. 2008
    ....
  29. ncbi request reprint Differential expression of c-fos and tyrosine hydroxylase mRNA in the adrenal gland of the infant rat: evidence for an adrenal hyporesponsive period
    Darren K Okimoto
    Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA
    Endocrinology 143:1717-25. 2002
    ..These results demonstrate that the suppression of steroidogenesis occurs directly in the adrenal cortex and provide further evidence for an adrenal hyporesponsive period in the rat...
  30. ncbi request reprint The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation
    Mathias V Schmidt
    Leiden Amsterdam Center for Drug Research Leiden University Medical Center, Division of Medical Pharmacology, Gorlaeus Laboratories, PO Box 9502, 2300 RA Leiden, The Netherlands
    Brain Res Dev Brain Res 139:39-49. 2002
    ....
  31. ncbi request reprint Maternal deprivation increases cell death in the infant rat brain
    Li Xin Zhang
    Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Brain Res Dev Brain Res 133:1-11. 2002
    ....