Research Topics
| Pamela ButlerSummaryAffiliation: Nathan Kline Institute Country: USA Publications
Research Grants
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Detail Information
Publications
DTI and impulsivity in schizophrenia: a first voxelwise correlational analysisMatthew J Hoptman
Division of Clinical Research, Nathan Kline Institute, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
Neuroreport 15:2467-70. 2004..These areas may comprise a fronto-temporo-limbic circuit that modulates impulsivity. The voxelwise correlation method can serve as a hypothesis-generation method for relating target behaviors to their underlying neural networks...
Dysfunction of early-stage visual processing in schizophreniaP D Butler
Department of Veterans Affairs New York Harbor Health Care System, New York, New York, USA
Am J Psychiatry 158:1126-33. 2001..Schizophrenia is associated with deficits in higher-order processing of visual information. This study evaluated the integrity of early visual processing in order to evaluate the overall pattern of visual dysfunction in schizophrenia...- Perceptual measurement in schizophrenia: promising electrophysiology and neuroimaging paradigms from CNTRICSPamela D Butler
Nathan Kline Institute for Psychiatric Research, Schizophrenia Research Center, Orangeburg, NY, USA
Schizophr Bull 38:81-91. 2012..This manuscript describes the ways in which each of these tasks met the criteria used in the breakout group to evaluate and recommend tasks for further development... - Has an important test been overlooked? Closure flexibility in schizophreniaPamela D Butler
Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
Schizophr Res 118:20-5. 2010..In addition, the CFT is a brief, easy to administer alphabet-independent, paper-and-pencil test with established psychometric properties that may be useful as an index of the sustained visual attention construct in schizophrenia... - Sensory contributions to impaired emotion processing in schizophreniaPamela D Butler
Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA
Schizophr Bull 35:1095-107. 2009..These results provide evidence for a contribution of impaired early-stage visual processing in emotion recognition deficits in schizophrenia and suggest that a bottom-up approach to remediation may be effective... - Visual perception and its impairment in schizophreniaPamela D Butler
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Biol Psychiatry 64:40-7. 2008.... - What's in a face? Effects of stimulus duration and inversion on face processing in schizophreniaPamela D Butler
Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
Schizophr Res 103:283-92. 2008..Similar inversion effects for face part and spacing for both groups suggest that they are using the same holistic face processing mechanism... - Visual white matter integrity in schizophreniaPamela D Butler
Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg NY, 10962, USA
Am J Psychiatry 163:2011-3. 2006..Patients with schizophrenia have visual-processing deficits. This study examines visual white matter integrity as a potential mechanism for these deficits... - Subcortical visual dysfunction in schizophrenia drives secondary cortical impairmentsPamela D Butler
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Brain 130:417-30. 2007.... - Early-stage visual processing and cortical amplification deficits in schizophreniaPamela D Butler
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Arch Gen Psychiatry 62:495-504. 2005..Investigating magnocellular dysfunction in schizophrenia therefore permits evaluation of underlying etiologic hypotheses... 
Auditory emotion recognition impairments in schizophrenia: relationship to acoustic features and cognitionRinat Gold
Center for Translational Schizophrenia Research, Orangeburg, NY, USA
Am J Psychiatry 169:424-32. 2012..The authors evaluated performance in schizophrenia on a novel voice emotion recognition battery with well-characterized physical features, relative to impairments in more general emotional and cognitive functioning...- Anticipated, on-line and remembered positive experience in schizophreniaFabien Tremeau
Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Schizophr Res 122:199-205. 2010..Moreover, the role of positive affect evaluations on motivation has rarely been studied in schizophrenia... - Dysfunction of early-stage visual processing in schizophrenia: harmonic analysisDongsoo Kim
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Schizophr Res 76:55-65. 2005..Early sensory deficits may lead to impairments in subsequent stages of processing... - Impairments in generation of early-stage transient visual evoked potentials to magno- and parvocellular-selective stimuli in schizophreniaIsaac Schechter
Nathan Kline Institute, Program in Cognitive Neuroscience and Schizophrenia, Orangeburg, NY 10962, USA
Clin Neurophysiol 116:2204-15. 2005..Further, between-group differences in visual acuity may influence VEP results, even for subjects with 'normal' vision (20/32 or better)... - In support of Bleuler: objective evidence for increased affective ambivalence in schizophrenia based upon evocative testingFabien Tremeau
Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, United States
Schizophr Res 107:223-31. 2009..These characteristics have not received much attention in schizophrenia research... - Neurocognitive and symptom correlates of daily problem-solving skills in schizophreniaNadine Revheim
Program in Cognitive Neuroscience and Schizophrenia, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Res 83:237-45. 2006..The findings suggest the ILS-PB has utility as a proxy measure for assessing real-world functioning in schizophrenia... - Getting the cue: sensory contributions to auditory emotion recognition impairments in schizophreniaDavid I Leitman
Program in Cognitive Neuroscience and Schizophrenia, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Bull 36:545-56. 2010.... - Emotion antecedents in schizophreniaFabien Tremeau
Clinical Research and Evaluation Facility, Nathan S Kline Institute for Psychiatric Research and Rockland Psychiatric Center, Orangeburg, NY 10962, USA
Psychiatry Res 169:43-50. 2009..Lower accuracy rates with schizophrenia subjects' antecedents may reflect lower emotion awareness for all emotions in schizophrenia. This study furthers the understanding of deficits in basic emotion processing in schizophrenia... - Sensory contributions to impaired prosodic processing in schizophreniaDavid I Leitman
Program in Cognitive Neuroscience and Schizophrenia, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Biol Psychiatry 58:56-61. 2005..The separate loading of auditory and visual affective recognition measures suggests that within-modality factors may be more significant than cross-modality factors in the etiology of affect recognition deficits in schizophrenia... - Visual backward-masking deficits in schizophrenia: relationship to visual pathway function and symptomatologyPamela D Butler
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
Schizophr Res 59:199-209. 2003.... - Magnocellular contributions to impaired motion processing in schizophreniaDongsoo Kim
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, New York 10962, USA
Schizophr Res 82:1-8. 2006..Further, this study supports and extends prior reports of impaired motion processing in schizophrenia, and indicates significant bottom-up contributions to higher-order cognitive impairments... - Impaired visual object processing across an occipital-frontal-hippocampal brain network in schizophrenia: an integrated neuroimaging studyPejman Sehatpour
Conte Center for Schizophrenia Research, Cognitive Neurophysiology Laboratory, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
Arch Gen Psychiatry 67:772-82. 2010.... - Magnocellular and parvocellular contributions to backward masking dysfunction in schizophreniaIsaac Schechter
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Res 64:91-101. 2003..Furthermore, deficits of letter identification, including those of P targets, may also reflect impairment of the M pathway given the priming function of the dorsal stream... - Brain morphometry using diffusion-weighted magnetic resonance imaging: application to schizophreniaBabak A Ardekani
Center for Advanced Brain Imaging, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, USA
Neuroreport 16:1455-9. 2005..Affected areas included the bilateral insular cortex, hippocampus, temporal lobe, and occipital areas. These results largely concur with previous findings of cortical volume deficits in schizophrenia... - Amplitude of low-frequency oscillations in schizophrenia: a resting state fMRI studyMatthew J Hoptman
Division of Clinical Research, Nathan Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Res 117:13-20. 2010..These results suggest LFO abnormalities in schizophrenia. The implication of these abnormalities for schizophrenic symptomatology is further discussed... - Seeing the world dimly: the impact of early visual deficits on visual experience in schizophreniaJoshua T Kantrowitz
Department of Life Sciences, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
Schizophr Bull 35:1085-94. 2009..01). This study replicates and expands upon previous findings with visual illusions. Our results offer a unifying explanation for disparate studies and suggest that deficits in early sensory gain affect subsequent integrative processes... - A new dimension of sensory dysfunction: stereopsis deficits in schizophreniaIsaac Schechter
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
Biol Psychiatry 60:1282-4. 2006..Early visual processing has been shown to be especially impaired. This article investigates the integrity of binocular depth perception (stereopsis) in schizophrenia... - Reading impairment and visual processing deficits in schizophreniaNadine Revheim
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Res 87:238-45. 2006..Findings related to symptoms, functioning and recommendations for reading ability assessment are discussed... - Magnocellular pathway impairment in schizophrenia: evidence from functional magnetic resonance imagingAntigona Martinez
Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
J Neurosci 28:7492-500. 2008.... - Perceptual organization by proximity and similarity in schizophreniaDaniel D Kurylo
Psychology Department, Brooklyn College CUNY, 2900 Bedford Avenue, Brooklyn, NY 11210, USA
Schizophr Res 95:205-14. 2007..Although this study did not directly investigate the physiological correlates underlying perceptual impairments, these results are consistent with a theory of impaired lateral connections within visual cortical areas in schizophrenia... - Voxelwise correlational analyses of white matter integrity in multiple cognitive domains in schizophreniaKelvin O Lim
Department of Psychiatry, University of Minnesota, Minneapolis 55455, USA
Am J Psychiatry 163:2008-10. 2006..In each case, better performance on these tasks was associated with higher levels of fractional anisotropy in task-relevant regions... - Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor bindingAbraham A Palmer
Department of Pharmacology, University of California San Diego, La Jolla, CA 92093, USA
Brain Res 996:193-201. 2004..This animal model may be useful for the investigation of neurodevelopmental changes that are associated with schizophrenia in humans...
Research Grants
- Visual Processing in SchizophreniaPamela Butler; Fiscal Year: 2007..abstract_text> ..
- Methods for Sensory Assessment in SchizophreniaPamela Butler; Fiscal Year: 2009..This project will develop standardized approaches to analyze sensory deficits in schizophrenia. ..