Pamela Butler

Summary

Affiliation: Nathan Kline Institute
Country: USA

Publications

  1. pmc DTI and impulsivity in schizophrenia: a first voxelwise correlational analysis
    Matthew J Hoptman
    Division of Clinical Research, Nathan Kline Institute, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
    Neuroreport 15:2467-70. 2004
  2. pmc An event-related potential examination of contour integration deficits in schizophrenia
    Pamela D Butler
    Schizophrenia Research Division, Nathan S Kline Institute for Psychiatric Research Orangeburg, NY, USA Department of Psychiatry, NYU School of Medicine New York, NY, USA Department of Psychology, City University of New York New York, NY, USA
    Front Psychol 4:132. 2013
  3. pmc Perceptual measurement in schizophrenia: promising electrophysiology and neuroimaging paradigms from CNTRICS
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, Schizophrenia Research Center, Orangeburg, NY, USA
    Schizophr Bull 38:81-91. 2012
  4. pmc Has an important test been overlooked? Closure flexibility in schizophrenia
    Pamela D Butler
    Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Schizophr Res 118:20-5. 2010
  5. pmc Sensory contributions to impaired emotion processing in schizophrenia
    Pamela D Butler
    Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA
    Schizophr Bull 35:1095-107. 2009
  6. pmc Visual perception and its impairment in schizophrenia
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Psychiatry 64:40-7. 2008
  7. pmc What's in a face? Effects of stimulus duration and inversion on face processing in schizophrenia
    Pamela D Butler
    Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Schizophr Res 103:283-92. 2008
  8. pmc Visual white matter integrity in schizophrenia
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg NY, 10962, USA
    Am J Psychiatry 163:2011-3. 2006
  9. pmc Subcortical visual dysfunction in schizophrenia drives secondary cortical impairments
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Brain 130:417-30. 2007
  10. ncbi request reprint Dysfunction of early-stage visual processing in schizophrenia
    P D Butler
    Department of Veterans Affairs New York Harbor Health Care System, New York, New York, USA
    Am J Psychiatry 158:1126-33. 2001

Research Grants

  1. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2004
  2. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2005
  3. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2006
  4. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2007
  5. Methods for Sensory Assessment in Schizophrenia
    Pamela Butler; Fiscal Year: 2009

Detail Information

Publications33

  1. pmc DTI and impulsivity in schizophrenia: a first voxelwise correlational analysis
    Matthew J Hoptman
    Division of Clinical Research, Nathan Kline Institute, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
    Neuroreport 15:2467-70. 2004
    ..These areas may comprise a fronto-temporo-limbic circuit that modulates impulsivity. The voxelwise correlation method can serve as a hypothesis-generation method for relating target behaviors to their underlying neural networks...
  2. pmc An event-related potential examination of contour integration deficits in schizophrenia
    Pamela D Butler
    Schizophrenia Research Division, Nathan S Kline Institute for Psychiatric Research Orangeburg, NY, USA Department of Psychiatry, NYU School of Medicine New York, NY, USA Department of Psychology, City University of New York New York, NY, USA
    Front Psychol 4:132. 2013
    ..These results are in accord with impairments in distributed circuitry contributing to perceptual organization deficits and provide an ERP analog to the behavioral contour integration task...
  3. pmc Perceptual measurement in schizophrenia: promising electrophysiology and neuroimaging paradigms from CNTRICS
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, Schizophrenia Research Center, Orangeburg, NY, USA
    Schizophr Bull 38:81-91. 2012
    ..This manuscript describes the ways in which each of these tasks met the criteria used in the breakout group to evaluate and recommend tasks for further development...
  4. pmc Has an important test been overlooked? Closure flexibility in schizophrenia
    Pamela D Butler
    Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Schizophr Res 118:20-5. 2010
    ..In addition, the CFT is a brief, easy to administer alphabet-independent, paper-and-pencil test with established psychometric properties that may be useful as an index of the sustained visual attention construct in schizophrenia...
  5. pmc Sensory contributions to impaired emotion processing in schizophrenia
    Pamela D Butler
    Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA
    Schizophr Bull 35:1095-107. 2009
    ..These results provide evidence for a contribution of impaired early-stage visual processing in emotion recognition deficits in schizophrenia and suggest that a bottom-up approach to remediation may be effective...
  6. pmc Visual perception and its impairment in schizophrenia
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Psychiatry 64:40-7. 2008
    ....
  7. pmc What's in a face? Effects of stimulus duration and inversion on face processing in schizophrenia
    Pamela D Butler
    Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Schizophr Res 103:283-92. 2008
    ..Similar inversion effects for face part and spacing for both groups suggest that they are using the same holistic face processing mechanism...
  8. pmc Visual white matter integrity in schizophrenia
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg NY, 10962, USA
    Am J Psychiatry 163:2011-3. 2006
    ..Patients with schizophrenia have visual-processing deficits. This study examines visual white matter integrity as a potential mechanism for these deficits...
  9. pmc Subcortical visual dysfunction in schizophrenia drives secondary cortical impairments
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Brain 130:417-30. 2007
    ....
  10. ncbi request reprint Dysfunction of early-stage visual processing in schizophrenia
    P D Butler
    Department of Veterans Affairs New York Harbor Health Care System, New York, New York, USA
    Am J Psychiatry 158:1126-33. 2001
    ..Schizophrenia is associated with deficits in higher-order processing of visual information. This study evaluated the integrity of early visual processing in order to evaluate the overall pattern of visual dysfunction in schizophrenia...
  11. pmc Early-stage visual processing and cortical amplification deficits in schizophrenia
    Pamela D Butler
    Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Arch Gen Psychiatry 62:495-504. 2005
    ..Investigating magnocellular dysfunction in schizophrenia therefore permits evaluation of underlying etiologic hypotheses...
  12. pmc Auditory emotion recognition impairments in schizophrenia: relationship to acoustic features and cognition
    Rinat Gold
    Center for Translational Schizophrenia Research, Orangeburg, NY, USA
    Am J Psychiatry 169:424-32. 2012
    ..The authors evaluated performance in schizophrenia on a novel voice emotion recognition battery with well-characterized physical features, relative to impairments in more general emotional and cognitive functioning...
  13. doi request reprint Anticipated, on-line and remembered positive experience in schizophrenia
    Fabien Tremeau
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Schizophr Res 122:199-205. 2010
    ..Moreover, the role of positive affect evaluations on motivation has rarely been studied in schizophrenia...
  14. ncbi request reprint Dysfunction of early-stage visual processing in schizophrenia: harmonic analysis
    Dongsoo Kim
    Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Schizophr Res 76:55-65. 2005
    ..Early sensory deficits may lead to impairments in subsequent stages of processing...
  15. pmc Impairments in generation of early-stage transient visual evoked potentials to magno- and parvocellular-selective stimuli in schizophrenia
    Isaac Schechter
    Nathan Kline Institute, Program in Cognitive Neuroscience and Schizophrenia, Orangeburg, NY 10962, USA
    Clin Neurophysiol 116:2204-15. 2005
    ..normal volunteers first to evaluate relative contributions of M and P systems to specific tVEP components in schizophrenia and, second, to evaluate integrity of early M and P processing in schizophrenia...
  16. doi request reprint In support of Bleuler: objective evidence for increased affective ambivalence in schizophrenia based upon evocative testing
    Fabien Tremeau
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, United States
    Schizophr Res 107:223-31. 2009
    ..These characteristics have not received much attention in schizophrenia research...
  17. ncbi request reprint Neurocognitive and symptom correlates of daily problem-solving skills in schizophrenia
    Nadine Revheim
    Program in Cognitive Neuroscience and Schizophrenia, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Schizophr Res 83:237-45. 2006
    ..The findings suggest the ILS-PB has utility as a proxy measure for assessing real-world functioning in schizophrenia...
  18. doi request reprint Emotion antecedents in schizophrenia
    Fabien Tremeau
    Clinical Research and Evaluation Facility, Nathan S Kline Institute for Psychiatric Research and Rockland Psychiatric Center, Orangeburg, NY 10962, USA
    Psychiatry Res 169:43-50. 2009
    ..Lower accuracy rates with schizophrenia subjects' antecedents may reflect lower emotion awareness for all emotions in schizophrenia. This study furthers the understanding of deficits in basic emotion processing in schizophrenia...
  19. pmc Getting the cue: sensory contributions to auditory emotion recognition impairments in schizophrenia
    David I Leitman
    Program in Cognitive Neuroscience and Schizophrenia, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Schizophr Bull 36:545-56. 2010
    ....
  20. ncbi request reprint Sensory contributions to impaired prosodic processing in schizophrenia
    David I Leitman
    Program in Cognitive Neuroscience and Schizophrenia, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Psychiatry 58:56-61. 2005
    ..Within the auditory domain, patients show difficulty in interpreting vocal emotional cues based on intonation (prosody). The relationship of these symptoms to deficits in basic sensory processing has not been previously evaluated...
  21. ncbi request reprint Visual backward-masking deficits in schizophrenia: relationship to visual pathway function and symptomatology
    Pamela D Butler
    Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
    Schizophr Res 59:199-209. 2003
    ....
  22. pmc Magnocellular contributions to impaired motion processing in schizophrenia
    Dongsoo Kim
    Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, New York 10962, USA
    Schizophr Res 82:1-8. 2006
    ..Further, this study supports and extends prior reports of impaired motion processing in schizophrenia, and indicates significant bottom-up contributions to higher-order cognitive impairments...
  23. pmc Brain morphometry using diffusion-weighted magnetic resonance imaging: application to schizophrenia
    Babak A Ardekani
    Center for Advanced Brain Imaging, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York, USA
    Neuroreport 16:1455-9. 2005
    ..Affected areas included the bilateral insular cortex, hippocampus, temporal lobe, and occipital areas. These results largely concur with previous findings of cortical volume deficits in schizophrenia...
  24. doi request reprint Impaired visual object processing across an occipital-frontal-hippocampal brain network in schizophrenia: an integrated neuroimaging study
    Pejman Sehatpour
    Conte Center for Schizophrenia Research, Cognitive Neurophysiology Laboratory, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Arch Gen Psychiatry 67:772-82. 2010
    ....
  25. ncbi request reprint Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia
    Isaac Schechter
    Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Schizophr Res 64:91-101. 2003
    ..Furthermore, deficits of letter identification, including those of P targets, may also reflect impairment of the M pathway given the priming function of the dorsal stream...
  26. pmc Amplitude of low-frequency oscillations in schizophrenia: a resting state fMRI study
    Matthew J Hoptman
    Division of Clinical Research, Nathan Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Schizophr Res 117:13-20. 2010
    ..These results suggest LFO abnormalities in schizophrenia. The implication of these abnormalities for schizophrenic symptomatology is further discussed...
  27. pmc Seeing the world dimly: the impact of early visual deficits on visual experience in schizophrenia
    Joshua T Kantrowitz
    Department of Life Sciences, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
    Schizophr Bull 35:1085-94. 2009
    ..01). This study replicates and expands upon previous findings with visual illusions. Our results offer a unifying explanation for disparate studies and suggest that deficits in early sensory gain affect subsequent integrative processes...
  28. pmc A new dimension of sensory dysfunction: stereopsis deficits in schizophrenia
    Isaac Schechter
    Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    Biol Psychiatry 60:1282-4. 2006
    ..Early visual processing has been shown to be especially impaired. This article investigates the integrity of binocular depth perception (stereopsis) in schizophrenia...
  29. pmc Reading impairment and visual processing deficits in schizophrenia
    Nadine Revheim
    Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Schizophr Res 87:238-45. 2006
    ..Findings related to symptoms, functioning and recommendations for reading ability assessment are discussed...
  30. doi request reprint Magnocellular pathway impairment in schizophrenia: evidence from functional magnetic resonance imaging
    Antigona Martinez
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 28:7492-500. 2008
    ....
  31. pmc Voxelwise correlational analyses of white matter integrity in multiple cognitive domains in schizophrenia
    Kelvin O Lim
    Department of Psychiatry, University of Minnesota, Minneapolis 55455, USA
    Am J Psychiatry 163:2008-10. 2006
    ..In each case, better performance on these tasks was associated with higher levels of fractional anisotropy in task-relevant regions...
  32. pmc Perceptual organization by proximity and similarity in schizophrenia
    Daniel D Kurylo
    Psychology Department, Brooklyn College CUNY, 2900 Bedford Avenue, Brooklyn, NY 11210, USA
    Schizophr Res 95:205-14. 2007
    ..Although this study did not directly investigate the physiological correlates underlying perceptual impairments, these results are consistent with a theory of impaired lateral connections within visual cortical areas in schizophrenia...
  33. ncbi request reprint Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor binding
    Abraham A Palmer
    Department of Pharmacology, University of California San Diego, La Jolla, CA 92093, USA
    Brain Res 996:193-201. 2004
    ..This animal model may be useful for the investigation of neurodevelopmental changes that are associated with schizophrenia in humans...

Research Grants6

  1. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2004
    ..abstract_text> ..
  2. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2005
    ..abstract_text> ..
  3. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2006
    ..abstract_text> ..
  4. Visual Processing in Schizophrenia
    Pamela Butler; Fiscal Year: 2007
    ..abstract_text> ..
  5. Methods for Sensory Assessment in Schizophrenia
    Pamela Butler; Fiscal Year: 2009
    ..This project will develop standardized approaches to analyze sensory deficits in schizophrenia. ..