Babak A Ardekani

..For small initial misalignments, TRU's performance was similar to SPM99 and AFNI98. However, its accuracy diminished rapidly for larger misalignments. AIR was found to be the least accurate program studied...

..Overall, the average Euclidean distance between automatically and manually detected landmarks was 1.1 mm. A software implementation of the algorithm is freely available online at www.nitrc.org/projects/art...

..In this paper, we present an entropy-based cost function, closely related to MI, that can be made relatively insensitive to interpolation effects, and can be generalized to registration of multispectral images...

..Patterns of water self-diffusion in the brain as estimated by DTI can be used in conjunction with automated pattern recognition algorithms to reliably distinguish between patients with schizophrenia and normal control subjects...

..The spatial dispersion measure was found to be more sensitive when the landmarks were placed after image registration. The standard deviation measure was found sensitive to intensity normalization or the method of image interpolation...

..Regions showing reduced white matter fractional anisotropy are known to be abnormal in schizophrenia. The voxelwise method used in the current study can provide the basis for hypothesis-driven research...

..Activation of thalamus, insula, and the occipitotemporal cortex has been reported less consistently. The present study lends further support to the involvement of these structures in visual target detection...

..Analysis of simulated data and motor task fMRI datasets from six volunteers using the method proposed here showed an improved sensitivity as compared to a conventional test with a similar statistic applied to spatially smoothed data...

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..These areas may comprise a fronto-temporo-limbic circuit that modulates impulsivity. The voxelwise correlation method can serve as a hypothesis-generation method for relating target behaviors to their underlying neural networks...

..Affected areas included the bilateral insular cortex, hippocampus, temporal lobe, and occipital areas. These results largely concur with previous findings of cortical volume deficits in schizophrenia...

..We now extend this finding to specifically examine functional activity in three language related cortical regions using a larger cohort of individuals...

..Diffusion tensor imaging may be sufficiently sensitive to detect preclinical brain changes related to Alzheimer's disease...

..If language pathway abnormalities can be detected early in people at high-risk for schizophrenia prior to the onset of symptoms, early treatment can ensue...

..Comparisons have been made between the results of the proposed method, a similar method in the time domain and the cross-correlation method. The proposed method has shown superior sensitivity compared to the other methods...

..It is concluded that ADC may be a more sensitive measure than ventricular volume assessments for use in future studies of early prediction of schizophrenia...

..This study examined whether and in which brain regions blood pressure is associated with compromised white matter integrity in elderly depressed patients...

..Additionally, 3D visualization of intra-regional distributions of T2 of the resultant registered images provided the ability to detect small changes between groups that otherwise would not be possible to detect...

..There is increasing evidence that schizophrenia is characterized by abnormalities in white matter...

..These abnormalities have clinical and neuropsychological correlates, which may be useful in further characterizing structure-function relations in schizophrenia and constraining neurobiological models of the disorder...

..This finding indicates that a dysfunctional frontoparietal circuit may underlie the low P300 responses seen in HR subjects. This perhaps implies a deficiency in the rehearsal component of the working memory system...

..In each case, better performance on these tasks was associated with higher levels of fractional anisotropy in task-relevant regions...

..To investigate abnormalities in the structural integrity of brain white matter as suggested by diffusion tensor imaging in adolescents with early-onset schizophrenia (onset of psychosis by age 18)...

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..The goal of this study was to investigate brain white matter abnormalities by using diffusion tensor imaging in patients with schizophrenia or schizoaffective disorder close to illness onset...

..Based upon the literature, we predicted decreased fractional anisotropy (FA) findings in the frontal and cerebellar regions...

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..The utility of the proposed basis functions in identifying the HRF is demonstrated by estimating the HRF in different activated regions...

..The objective of this study was to identify subtle white matter abnormalities in late-life depression...

..The authors investigated WM development in healthy adolescent males through age-associated changes in fractional anisotropy (FA), radial (lambda( perpendicular)) and axial (lambda(||)) diffusivity...

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