John T James

Summary

Affiliation: NASA Ames Research Center
Country: USA

Publications

  1. doi request reprint Estimate of safe human exposure levels for lunar dust based on comparative benchmark dose modeling
    John T James
    Space Toxicology Office, National Aeronautics and Space Administration Johnson Space Center, Houston, TX 77058, USA
    Inhal Toxicol 25:243-56. 2013
  2. ncbi request reprint Prediction of crew health effects from air samples taken aboard the International Space Station
    John T James
    NASA Johnson Space Center, Houston, TX 77058, USA
    Aviat Space Environ Med 83:795-9. 2012
  3. ncbi request reprint Pulmonary toxicity of simulated lunar and Martian dusts in mice: II. Biomarkers of acute responses after intratracheal instillation
    Chiu wing Lam
    Wyle Laboratories, NASA Johnson Space Center, Houston, Texas 77058, USA
    Inhal Toxicol 14:917-28. 2002
  4. ncbi request reprint A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks
    Chiu wing Lam
    JSC Toxicology Group, Space Life Sciences, NASA Johnson Space Center, Wyle Laboratories and Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, Texas 77058, USA
    Crit Rev Toxicol 36:189-217. 2006
  5. ncbi request reprint Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation
    Chiu wing Lam
    Space and Life Sciences, NASA Johnson Space Center, Houston, Texas 77058, USA
    Toxicol Sci 77:126-34. 2004
  6. doi request reprint Space toxicology: protecting human health during space operations
    Noreen Khan-Mayberry
    NASA Johnson Space Center, Houston, TX 77058, USA
    Int J Toxicol 30:3-18. 2011
  7. pmc Ocular toxicity of authentic lunar dust
    Valerie E Meyers
    Space Toxicology Office, NASA Johnson Space Center, 2101 NASA Parkway, MC SF23, Houston, TX 77058, USA
    BMC Ophthalmol 12:26. 2012
  8. ncbi request reprint Pulmonary toxicity of simulated lunar and Martian dusts in mice: I. Histopathology 7 and 90 days after intratracheal instillation
    Chiu wing Lam
    Wyle Laboratories, NASA Johnson Space Center, Houston, Texas 77058, USA
    Inhal Toxicol 14:901-16. 2002
  9. ncbi request reprint Acceptable levels for ingestion of dimethylsilanediol in water on the International Space Station
    Raghupathy Ramanathan
    Habitability and Environmental Factors Branch, NASA Johnson Space Center, 2101 NASA Parkway, Mail Stop SF2, Houston TX 77058, USA
    Aviat Space Environ Med 83:598-603. 2012

Collaborators

Detail Information

Publications9

  1. doi request reprint Estimate of safe human exposure levels for lunar dust based on comparative benchmark dose modeling
    John T James
    Space Toxicology Office, National Aeronautics and Space Administration Johnson Space Center, Houston, TX 77058, USA
    Inhal Toxicol 25:243-56. 2013
    ..0 ± 0.5 mg/m³ (ball-milled dust) and 0.9 ± 0.3 mg/m³ (unground, natural dust). We estimate that 0.5-1 mg/m³ of lunar dust is safe for periodic human exposures during long stays in habitats on the lunar surface...
  2. ncbi request reprint Prediction of crew health effects from air samples taken aboard the International Space Station
    John T James
    NASA Johnson Space Center, Houston, TX 77058, USA
    Aviat Space Environ Med 83:795-9. 2012
    ..Herein, air monitoring data from the ISS are used to demonstrate a new method to estimate a threshold for possible health effects from exposure to mixtures...
  3. ncbi request reprint Pulmonary toxicity of simulated lunar and Martian dusts in mice: II. Biomarkers of acute responses after intratracheal instillation
    Chiu wing Lam
    Wyle Laboratories, NASA Johnson Space Center, Houston, Texas 77058, USA
    Inhal Toxicol 14:917-28. 2002
    ..These results were consistent with the subchronic histopathological findings in that the order of severity of lung toxicity was TiO(2) < LSS < MSS < quartz...
  4. ncbi request reprint A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks
    Chiu wing Lam
    JSC Toxicology Group, Space Life Sciences, NASA Johnson Space Center, Wyle Laboratories and Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, Texas 77058, USA
    Crit Rev Toxicol 36:189-217. 2006
    ..Therefore, CNTs from manufactured and combustion sources in the environment could have adverse effects on human health...
  5. ncbi request reprint Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation
    Chiu wing Lam
    Space and Life Sciences, NASA Johnson Space Center, Houston, Texas 77058, USA
    Toxicol Sci 77:126-34. 2004
    ....
  6. doi request reprint Space toxicology: protecting human health during space operations
    Noreen Khan-Mayberry
    NASA Johnson Space Center, Houston, TX 77058, USA
    Int J Toxicol 30:3-18. 2011
    ..As we begin to explore other celestial bodies, in situ toxicological risks, such as inhalation of reactive mineral dusts, must also be managed...
  7. pmc Ocular toxicity of authentic lunar dust
    Valerie E Meyers
    Space Toxicology Office, NASA Johnson Space Center, 2101 NASA Parkway, MC SF23, Houston, TX 77058, USA
    BMC Ophthalmol 12:26. 2012
    ..Visual acuity is critical during exploration activities and operations aboard spacecraft. Therefore, the present research was performed to ascertain the ocular toxicity of authentic lunar dust...
  8. ncbi request reprint Pulmonary toxicity of simulated lunar and Martian dusts in mice: I. Histopathology 7 and 90 days after intratracheal instillation
    Chiu wing Lam
    Wyle Laboratories, NASA Johnson Space Center, Houston, Texas 77058, USA
    Inhal Toxicol 14:901-16. 2002
    ..This study showed that LSS and MSS are more hazardous in the lungs than nuisance dusts...
  9. ncbi request reprint Acceptable levels for ingestion of dimethylsilanediol in water on the International Space Station
    Raghupathy Ramanathan
    Habitability and Environmental Factors Branch, NASA Johnson Space Center, 2101 NASA Parkway, Mail Stop SF2, Houston TX 77058, USA
    Aviat Space Environ Med 83:598-603. 2012
    ..As no standard existed for safe levels of DMSD in water, the Toxicology Office at Johnson Space Center was asked to set such a standard...