Ying Huang

Summary

Affiliation: Nanogen Inc
Country: USA

Publications

  1. ncbi request reprint Electric manipulation of bioparticles and macromolecules on microfabricated electrodes
    Y Huang
    Nanogen Inc, San Diego, California 92121, USA
    Anal Chem 73:1549-59. 2001
  2. pmc Multiplex assay for simultaneously typing and subtyping influenza viruses by use of an electronic microarray
    Ying Huang
    Nanogen Inc, San Diego, CA 92121
    J Clin Microbiol 47:390-6. 2009
  3. ncbi request reprint Multiple sample amplification and genotyping integrated on a single electronic microarray
    Ying Huang
    Nanogen Inc, San Diego, CA 92121, USA
    Electrophoresis 25:3106-16. 2004
  4. ncbi request reprint Dielectrophoretic cell separation and gene expression profiling on microelectronic chip arrays
    Ying Huang
    Department of Advanced Technology, Nanogen Inc, San Diego, California 92121, USA
    Anal Chem 74:3362-71. 2002
  5. ncbi request reprint An integrated, stacked microlaboratory for biological agent detection with DNA and immunoassays
    Joon Mo Yang
    Nanogen, Inc, 10398 Pacific Center Court, San Diego, CA 92121, USA
    Biosens Bioelectron 17:605-18. 2002
  6. ncbi request reprint MEMS-based sample preparation for molecular diagnostics
    Ying Huang
    Nanogen Inc, San Diego, California 92121, USA
    Anal Bioanal Chem 372:49-65. 2002
  7. ncbi request reprint Classification of Streptomyces griseus (Krainsky 1914) Waksman and Henrici 1948 and related species and the transfer of 'Microstreptospora cinerea' to the genus Streptomyces as Streptomyces yanii sp. nov
    Zhiheng Liu
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    Int J Syst Evol Microbiol 55:1605-10. 2005
  8. ncbi request reprint Y chromosomes of prehistoric people along the Yangtze River
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China
    Hum Genet 122:383-8. 2007
  9. ncbi request reprint Human IgG1 Cgamma1 domain is crucial for the bioactivity of the engineered anti-CD20 antibodies
    Shusheng Geng
    College of Life Science, Hebei University, Baoding, China
    Cell Mol Immunol 4:121-5. 2007
  10. ncbi request reprint Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1
    Ying Huang
    Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA
    Pharm Res 24:1702-12. 2007

Research Grants

Collaborators

Detail Information

Publications64

  1. ncbi request reprint Electric manipulation of bioparticles and macromolecules on microfabricated electrodes
    Y Huang
    Nanogen Inc, San Diego, California 92121, USA
    Anal Chem 73:1549-59. 2001
    ..According to these results, the electric methods for manipulating bioparticles present themselves as viable techniques for novel biomedical applications in sample preparations and biochemical assays on microelectrode arrays...
  2. pmc Multiplex assay for simultaneously typing and subtyping influenza viruses by use of an electronic microarray
    Ying Huang
    Nanogen Inc, San Diego, CA 92121
    J Clin Microbiol 47:390-6. 2009
    ..The assay is a rapid, accurate, user-friendly method for simultaneously typing and subtyping influenza viruses...
  3. ncbi request reprint Multiple sample amplification and genotyping integrated on a single electronic microarray
    Ying Huang
    Nanogen Inc, San Diego, CA 92121, USA
    Electrophoresis 25:3106-16. 2004
    ....
  4. ncbi request reprint Dielectrophoretic cell separation and gene expression profiling on microelectronic chip arrays
    Ying Huang
    Department of Advanced Technology, Nanogen Inc, San Diego, California 92121, USA
    Anal Chem 74:3362-71. 2002
    ..The presented approach of using microelectronic chip arrays for both cell separation and gene expression profiling provides a great potential for accurate genetic analysis of specific cell subpopulations in heterogeneous samples...
  5. ncbi request reprint An integrated, stacked microlaboratory for biological agent detection with DNA and immunoassays
    Joon Mo Yang
    Nanogen, Inc, 10398 Pacific Center Court, San Diego, CA 92121, USA
    Biosens Bioelectron 17:605-18. 2002
    ..The integrated microlaboratory can be potentially used in a wide range of applications including detection of bacteria and biowarfare agents, and genetic identification...
  6. ncbi request reprint MEMS-based sample preparation for molecular diagnostics
    Ying Huang
    Nanogen Inc, San Diego, California 92121, USA
    Anal Bioanal Chem 372:49-65. 2002
    ....
  7. ncbi request reprint Classification of Streptomyces griseus (Krainsky 1914) Waksman and Henrici 1948 and related species and the transfer of 'Microstreptospora cinerea' to the genus Streptomyces as Streptomyces yanii sp. nov
    Zhiheng Liu
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    Int J Syst Evol Microbiol 55:1605-10. 2005
    ..It is proposed that S. caviscabies and S. setonii should be considered as later heterotypic synonyms of S. griseus and that S. argenteolus AS 4.1693(T) should also be assigned to this taxon...
  8. ncbi request reprint Y chromosomes of prehistoric people along the Yangtze River
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China
    Hum Genet 122:383-8. 2007
    ..Noticeable genetic segregation was observed among the prehistoric cultures, demonstrating the genetic foundation of the multiple origins of the Chinese Civilization...
  9. ncbi request reprint Human IgG1 Cgamma1 domain is crucial for the bioactivity of the engineered anti-CD20 antibodies
    Shusheng Geng
    College of Life Science, Hebei University, Baoding, China
    Cell Mol Immunol 4:121-5. 2007
    ..Our study highlights some interests and advantages of a methodology based on the homology modeling and analysis of molecular structural properties...
  10. ncbi request reprint Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1
    Ying Huang
    Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA
    Pharm Res 24:1702-12. 2007
    ..We hypothesized that membrane transporters on tumor cells determine at least in part the response to GA analogues...
  11. ncbi request reprint Structured to reduce the mitogenicity of anti-CD3 antibody based on computer-guided molecular design
    Ming Lv
    Institute of Basic Medical Sciences, Beijing, PR China
    Int J Biochem Cell Biol 39:1142-55. 2007
    ....
  12. ncbi request reprint Ruania albidiflava gen. nov., sp. nov., a novel member of the suborder Micrococcineae
    Qiang Gu
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China
    Int J Syst Evol Microbiol 57:809-14. 2007
    ..nov., sp. nov. is proposed. The type strain of Ruania albidiflava is 3-6(T) (=CGMCC 4.3142(T)=DSM 18029(T)=JCM 13910(T)=PCM 2644(T))...
  13. ncbi request reprint Improved efficiency of bovine cloning by autologous somatic cell nuclear transfer
    Xiao yu Yang
    Shanghai Institute of Medical Genetics, Shanghai Children s Hospital, Shanghai Jiao Tong University, 24 1400 West Beijing Road, Shanghai 200040, People s Republic of China
    Reproduction 132:733-9. 2006
    ..This study indicates that autologous SCNT can improve the efficiency of bovine cloning with less reprogramming deficiency...
  14. ncbi request reprint Gordonia shandongensis sp. nov., isolated from soil in China
    Hongli Luo
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China
    Int J Syst Evol Microbiol 57:605-8. 2007
    ..nov. is proposed. The type strain is SD29(T) (=CGMCC 4.3492(T)=JCM 13907(T))...
  15. ncbi request reprint Binding activity difference of anti-CD20 scFv-Fc fusion protein derived from variable domain exchange
    Shu Sheng Geng
    College of Life Science, Hebei University, Baoding, Hebei, China
    Cell Mol Immunol 3:439-43. 2006
    ..The study highlights the potential relationship between the antibody binding activity and their 3-D conformation, which appears to be worthwhile in providing direction for future antibody design of recombinant antibody...
  16. pmc A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection
    Ying Huang
    Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:985-90. 2007
    ....
  17. pmc Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography
    Philippe Normand
    Universite de Lyon, UMR CNRS, 5557 Ecologie Microbienne, IFR41 Bio Environnement et Santé, Université Lyon I, Villeurbanne 69622 Cedex, France
    Genome Res 17:7-15. 2007
    ..The results support the idea that major genome expansions as well as reductions can occur in facultative symbiotic soil bacteria as they respond to new environments in the context of their symbioses...
  18. ncbi request reprint Effects of dopamine receptor type 1 and Gs protein alpha subunit gene polymorphisms on blood pressure at rest and in response to stress
    Yanhui Lu
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912 3715, USA
    Am J Hypertens 19:832-6. 2006
    ..Therefore, we investigated whether the A-48G polymorphism of the DRD1 gene and the T393C polymorphism of the Gs protein alpha subunit (GNAS) gene influenced BP levels at rest and in response to stress...
  19. pmc Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C
    Ying Huang
    Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Gastroenterology 132:733-44. 2007
    ..To understand IFN-alpha resistance in vivo, we examined the dynamic responses to both type I and type II IFNs, human IFN (hIFN)-alpha, -gamma, and consensus IFN, in the chimpanzee model...
  20. pmc A variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer
    Zhongning Lin
    Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, Arkansas, USA
    Hum Mutat 29:113-22. 2008
    ..Our data constituted strong evidence that ERCC6 rs3793784:C>G alters its transcriptional activity and may confer personalized susceptibility to lung cancer...
  21. ncbi request reprint Streptomyces emeiensis sp. nov., a novel streptomycete from soil in China
    Wei Sun
    The National Key Laboratory for Screening New Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing 100050, People s Republic of China
    Int J Syst Evol Microbiol 57:1635-9. 2007
    ..It is therefore concluded that strain 4776(T) (=CGMCC 4.3504(T)=DSM 41884(T)) represents a novel species of the genus Streptomyces, for which the name Streptomyces emeienseis sp. nov. is proposed...
  22. doi request reprint Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura
    Jie Tao
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin 300020, People s Republic of China
    J Clin Immunol 28:432-9. 2008
    ..The aim of this study is to explore if DNA methylation plays a role in the pathogenesis of idiopathic thrombocytopenic purpura (ITP)...
  23. pmc Selective isolation and rapid identification of members of the genus Micromonospora
    Danheng Qiu
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
    Appl Environ Microbiol 74:5593-7. 2008
    ..The robustness of both the isolation and the identification approach was underpinned by phylogenetic analysis based on 16S rRNA gene sequences...
  24. pmc Identification of metabolites with anticancer properties by computational metabolomics
    Adrian K Arakaki
    Center for the Study of Systems Biology, Georgia Institute of Technology, Atlanta, Georgia, USA
    Mol Cancer 7:57. 2008
    ..The fact that metabolites can affect the cancer process on so many levels suggests that the change in concentration of some metabolites that occurs in cancer cells could have an active role in the progress of the disease...
  25. doi request reprint A three-gene expression signature model to predict clinical outcome of clear cell renal carcinoma
    Masahiro Yao
    Department of Urology and Molecular Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Japan
    Int J Cancer 123:1126-32. 2008
    ....
  26. pmc Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions
    Yali Yang
    Department of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA
    Cancer Res 68:4077-85. 2008
    ....
  27. pmc Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignancies
    Chad A Corcoran
    Department of Pharmacology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Mol Cancer Res 6:795-807. 2008
    ..Collectively, our results have identified nSMase3 to be an important molecule that is linked to tumorigenesis and cellular stress response...
  28. ncbi request reprint Expression, purification and characterization of pectin methylesterase inhibitor from kiwi fruit in Escherichia coli
    Yanling Hao
    College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qing Hua East Road, Hai Dian District, Beijing 100083, PR China
    Protein Expr Purif 60:221-4. 2008
    ..0-10.0 and 20-40 degrees C. Thus, recombinant PMEI has potential application in the production of fruit juices product industry...
  29. doi request reprint A novel DNA vaccine for protective immunity against virulent Mycobacterium bovis in mice
    Siguo Liu
    Division of Bacterial Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 15000, PR China siguo
    Immunol Lett 117:136-45. 2008
    ..This suggests that fusion DNA vaccine represent a promising approach for the prevention of bTB...
  30. ncbi request reprint Lechevalieria xinjiangensis sp. nov., a novel actinomycete isolated from radiation-polluted soil in China
    Wei Wang
    Institute of Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, Xinjiang Uygur Autonomous Region, People s Republic of China
    Int J Syst Evol Microbiol 57:2819-22. 2007
    ..The name proposed for this taxon is Lechevalieria xinjiangensis sp. nov. The type strain is R24(T) (=CGMCC 4.3525(T)=DSM 45081(T))...
  31. ncbi request reprint Streptomyces radiopugnans sp. nov., a radiation-resistant actinomycete isolated from radiation-polluted soil in China
    Jun Mao
    Institute of Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, Xinjiang Uigur Autonomous Region, PR China
    Int J Syst Evol Microbiol 57:2578-82. 2007
    ..3519T=DSM 41901T) be classified as the type strain of a novel species in the genus Streptomyces, Streptomyces radiopugnans sp. nov. The organism was shown to be resistant to 60Co gamma radiation at a dose of 15 kGy...
  32. ncbi request reprint RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer
    Joanne Montalbano
    Department of Pharmacology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    J Biol Chem 282:37640-9. 2007
    ..Thus, RBEL1A and RBEL1B are novel Rab-like proteins that localize in the nucleus and cytosol and may play an important role in breast tumorigenesis...
  33. pmc Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response
    Jordan J Feld
    Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Hepatology 46:1548-63. 2007
    ..Collectively, these mechanisms may provide a molecular basis for the improved efficacy of combination therapy...
  34. ncbi request reprint Dual-tagging system for the affinity purification of mammalian protein complexes
    Richard J Giannone
    Oak Ridge National Laboratory, Oak Ridge, TN, USA
    Biotechniques 43:296, 298, 300 passim. 2007
    ....
  35. ncbi request reprint Neutrotolerant acidophilic Streptomyces species isolated from acidic soils in China: Streptomyces guanduensis sp. nov., Streptomyces paucisporeus sp. nov., Streptomyces rubidus sp. nov. and Streptomyces yanglinensis sp. nov
    Chunguang Xu
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    Int J Syst Evol Microbiol 56:1109-15. 2006
    ..2025T=JCM 13276T), Streptomyces rubidus sp. nov. (type strain 13c15T=CGMCC 4.2026T=JCM 13277T) and Streptomyces yanglinensis sp. nov. (type strain 1307T=CGMCC 4.2023T=JCM 13275T); isolates 317 and 913 belong to this latter species...
  36. ncbi request reprint Comparative proteomic analysis of hypoxia-treated and untreated human leukemic U937 cells
    Yu Hui Han
    Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P R China
    Proteomics 6:3262-74. 2006
    ..Moreover, enforced HIF-1alpha expression also elevated NDRG1 mRNA and protein in U937 cells. These data will provide some clues for understanding mechanisms by which leukemic cells response to hypoxia...
  37. ncbi request reprint Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance
    Ying Huang
    Program of Pharmacogenomics, Department of Pharmacology, College of Medicine and Public Health, The Ohio State University, Columbus, 43210, USA
    Cancer Res 64:4294-301. 2004
    ..Measurement of transporter gene expression may prove useful in predicting anticancer drug response...
  38. ncbi request reprint BOX-pCR fingerprinting as a powerful tool to reveal synonymous names in the genus Streptomyces. Emended descriptions are proposed for the species Streptomyces cinereorectus, S. fradiae, S. tricolor, S. colombiensis, S. filamentosus, S. vinaceus and S. pha
    Benjamin Lanoot
    BCCM LMG Bacteria Collection, Ghent University, Belgium
    Syst Appl Microbiol 27:84-92. 2004
    ..distallicus of S. colombiensis, S. arabicus of S. vinaceus and S. phaeoviridis of S. phaeopurpureus. Although not yet confirmed by DNA-DNA pairing studies, rep-PCR data suggested the presence of at least 33 additional junior synonyms...
  39. ncbi request reprint Death receptors as targets of cancer therapeutics
    M Saeed Sheikh
    Department of Pharmacology, State University of New York, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Curr Cancer Drug Targets 4:97-104. 2004
    ..This review discusses the pros and cons of targeting death receptors in the development of novel cancer therapeutic agents...
  40. ncbi request reprint Intestinal membrane transport of drugs and nutrients: genomics of membrane transporters using expression microarrays
    Pascale Anderle
    ISREC, Chemin des Boveresses 155, 1066 Epalinges s Lausanne, Switzerland
    Eur J Pharm Sci 21:17-24. 2004
    ..The resultant drug-transporter databases permit the search for transporter-drug relationships at a genomic scale...
  41. ncbi request reprint Prediction of protein subcellular locations using fuzzy k-NN method
    Ying Huang
    State Key Laboratory of Intelligent Technology and Systems, Department of Automation, Institute of Bioinformatics, Tsinghua University, Beijing 100084, People s Republic of China
    Bioinformatics 20:21-8. 2004
    ..Protein localization data are a valuable information resource helpful in elucidating protein functions. It is highly desirable to predict a protein's subcellular locations automatically from its sequence...
  42. ncbi request reprint Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells
    Qin He
    Department of Pharmacology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Oncogene 23:2554-8. 2004
    ..Our results have important clinical implications in that the use of Apo2L/TRAIL and proteasome inhibitors in combination could prove to be a novel therapeutic strategy to manage the Apo2L/TRAIL-resistant tumors...
  43. ncbi request reprint Glutamine decreases lipopolysaccharide-induced IL-8 production in Caco-2 cells through a non-NF-kappaB p50 mechanism
    Ying Huang
    Children s Hospital of Fudan University, 183 Fenglin Road, Shanghai 200032, People s Republic of China
    Cytokine 22:77-83. 2003
    ..However, the glutamine-mediated decrease in LPS-stimulated IL-8 production is not associated with NF-kappaB p50 nuclear binding...
  44. ncbi request reprint Drug sensitivity and resistance genes in cancer chemotherapy: a chemogenomics approach
    Ying Huang
    Program of Pharmacogenomics, Dept of Pharmacology, College of Medicine and Public Health, The Ohio State University, 5078 Graves Hall, 333 W 10th Avenue, Columbus, OH 43210, USA
    Drug Discov Today 8:356-63. 2003
    ..Therefore, validated pharmacogenomic biomarkers offer the potential for the selection of optimal treatment regimens for individual patients and for identifying novel therapeutic targets to overcome drug resistance...
  45. ncbi request reprint [Therapeutic effect of high-density lipoprotein of human plasma on rat endotoxemia]
    Ying Huang
    Department of Pathophysiology, West China School of Predinical and Forensic Medicine, Sichuan University, Chengdu 610041, China
    Hua Xi Yi Ke Da Xue Xue Bao 33:65-7. 2002
    ..To investigate the therapeutic effect of high-density lipoprotein (HDL) of human plasma on rat endotoxemia...
  46. ncbi request reprint Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme
    Han Ting Zhang
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Neuropsychopharmacology 27:587-95. 2002
    ....
  47. ncbi request reprint Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells
    Qin He
    Department of Pharmacology, State University of New York, Upstate Medical University, Syracuse, New York, NY 13210, USA
    Oncogene 21:6032-40. 2002
    ..In conclusion, the data presented herein form the basis of future in-depth studies to further explore the utility of Apo2L/TRAIL and NSAIDs, in combination, as a novel cancer preventive/therapeutic strategy...
  48. ncbi request reprint Proposal to combine the genera Actinobispora and Pseudonocardia in an emended genus Pseudonocardia, and description of Pseudonocardia zijingensis sp. nov
    Ying Huang
    Institute of Microbiology, Chinese Academy of Sciences, Beijing, People s Republic of China
    Int J Syst Evol Microbiol 52:977-82. 2002
    ..nov. The type strain is 6330T (= AS 4.1545T = JCM 11117T)...
  49. ncbi request reprint Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes
    Micheala A Aldred
    Human Cancer Genetics Program, The Ohio State University, Columbus, OH 43210, USA
    J Clin Oncol 22:3531-9. 2004
    ..In this study, we sought to combine our data sets to shed light on the similarities and differences between these tumor types...
  50. ncbi request reprint Growth factor signaling and resistance to cancer chemotherapy
    Zunyan Dai
    Program of Pharmacogenomics, Department of Pharmacology, College of Medicine and Public Health, The Ohio State University, 5168 Graves Hall, 333 West 10th Avenue, Columbus, OH 43210, USA
    Curr Top Med Chem 4:1347-56. 2004
    ..Monitoring expression profiles and activating mutations in growth factor receptors holds promise for the design of individualized therapy with a combination of drugs...
  51. ncbi request reprint Streptomyces glauciniger sp. nov., a novel mesophilic streptomycete isolated from soil in south China
    Ying Huang
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China
    Int J Syst Evol Microbiol 54:2085-9. 2004
    ..1858(T)=JCM 12278(T)=LMG 22082(T)) should be classified as the type strain of a novel species of the genus Streptomyces, for which the name Streptomyces glauciniger sp. nov. is proposed...
  52. ncbi request reprint Prediction of anticancer drug potency from expression of genes involved in growth factor signaling
    Zunyan Dai
    Program of Pharmacogenomics, Department of Pharmacology, The Ohio State University, 5078 Graves Hall, 333 West 10th Avenue, Columbus, 43210, USA
    Pharm Res 23:336-49. 2006
    ..This study develops and evaluates a systematic approach to finding biomarker genes for predicting potency of anticancer drugs against tumor cells, focusing on gene families related to growth factor signaling...
  53. ncbi request reprint Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells
    Hua Yan
    Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Rui Jin Hospital, Shanghai Jiao Tong University SJU SM, formerly named Shanghai Second Medical University, Shanghai 200025, China
    Haematologica 90:1607-16. 2005
    ....
  54. ncbi request reprint Translocation of positively charged copoly(Lys/Tyr) across phospholipid membranes
    Shaoqian Liu
    College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
    Biochem Biophys Res Commun 339:761-8. 2006
    ..In addition, we found that the translocation efficiency of copoly(Lys/Tyr) was higher on the EPC/DOPE lipid membrane than on the SBPL lipid membrane...
  55. ncbi request reprint Interferon-alpha-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cdelta and JNK
    Ke Wen Zhao
    Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis, Chinese Ministry of Education, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine formerly Shanghai Second Medical University, Shanghai 200025, China
    J Biol Chem 280:42707-14. 2005
    ..In conclusion, our results suggest that the induction of PLSCR1 transcription through STAT1 depends upon sequential activation of PKCdelta and JNK...
  56. ncbi request reprint Streptomyces jietaisiensis sp. nov., isolated from soil in northern China
    Liang He
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    Int J Syst Evol Microbiol 55:1939-44. 2005
    ..It is proposed, therefore, that this organism be classified as a novel species of the genus Streptomyces, for which the name Streptomyces jietaisiensis sp. nov. is proposed. The type strain is FXJ46(T) (=AS 4.1859(T)=JCM 12279(T))...
  57. ncbi request reprint Nocardia jiangxiensis sp. nov. and Nocardia miyunensis sp. nov., isolated from acidic soils
    Qingfeng Cui
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    Int J Syst Evol Microbiol 55:1921-5. 2005
    ..1904(T)=JCM 12860(T)) and 43401(T) (=CGMCC 4.1905(T)=JCM 12861(T)) be classified in the genus Nocardia as the type strains of Nocardia miyunensis sp. nov. and Nocardia jiangxiensis sp. nov., respectively...
  58. ncbi request reprint Sanguibacter marinus sp. nov., isolated from coastal sediment
    Ying Huang
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China
    Int J Syst Evol Microbiol 55:1755-8. 2005
    ..nov. is proposed. The type strain is 1-19(T) (=CGMCC 1.3457(T)=JCM 12547(T))...
  59. ncbi request reprint Grouping of streptomycetes using 16S-ITS RFLP fingerprinting
    Benjamin Lanoot
    BCCM LMG Bacteria Collection and Laboratorium voor Microbiologie, University Gent, K L Ledeganckstraat 35, 9000 Ghent, Belgium Benjamin Lanoot Ugent be
    Res Microbiol 156:755-62. 2005
    ....
  60. ncbi request reprint [Detection of Mobiluncus species by special primer amplification and 16S DNA sequence analysis]
    Liang He
    Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China
    Wei Sheng Wu Xue Bao 45:27-30. 2005
    ..The 16S rRNA gene was amplified and sequenced using mobiluncus-specific primers. Mobiluncus ssp, closely related to Mobiluncus mulieris, were detected, by comparing with the 16S rRNA genes in the GenBank...
  61. ncbi request reprint Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines
    Jim J Xiao
    College of Pharmacy, The Ohio State University, Columbus, OH, USA
    J Pharmacol Exp Ther 314:467-75. 2005
    ..This study reveals a significant role of histone acetylation in MDR1 transcription, which seems to mediate FK228 resistance...
  62. ncbi request reprint Induction of human T cell leukemia virus type I receptors on quiescent naive T lymphocytes by TGF-beta
    Kathryn S Jones
    Basic Research Program, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Frederick, MD 21702 1201, USA
    J Immunol 174:4262-70. 2005
    ....
  63. ncbi request reprint Kitasatospora viridis sp. nov., a novel actinomycete from soil
    Zhiheng Liu
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    Int J Syst Evol Microbiol 55:707-11. 2005
    ..The name proposed is Kitasatospora viridis sp. nov., with the type strain 52108a(T) (=AS 4.1878(T)=DSM 44826(T))...
  64. ncbi request reprint Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway
    Qin He
    Department of Pharmacology, State University of New York, Upstate Medical University, Syracuse, New York, NY 13210, USA
    Oncogene 21:2623-33. 2002
    ....

Research Grants1

  1. Dielectrophoretic Separator for Cell/Pathogen Separation
    Ying Huang; Fiscal Year: 2003
    ..There examples address the needs of lowering the threshold for detection of cancer cells in blood, with the goal of diagnosing infectious disease and biowarfare agents without the need to first culture the pathogens. ..