Stephen C Ward

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. doi request reprint Hepatic progenitor cells in liver cancers from Asian children
    Stephen C Ward
    Department of Pathology, The Mount Sinai Medical Center, New York, NY 10029, USA
    Liver Int 30:102-11. 2010
  2. ncbi request reprint Multifocal hepatocellular carcinoma and precancerous lesions in a patient with autoimmune hepatitis-related cirrhosis
    Stephen C Ward
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, The Mount Sinai Medical Center, New York, New York 10029, USA
    Semin Liver Dis 28:123-7. 2008
  3. doi request reprint Fibrolamellar carcinoma: a review with focus on genetics and comparison to other malignant primary liver tumors
    Stephen C Ward
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, Mount Sinai School of Medicine, New York, USA
    Semin Liver Dis 31:61-70. 2011
  4. doi request reprint Patient with hepatitis B and alcoholic liver disease before and after liver transplantation
    Stephen C Ward
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, The Mount Sinai Medical Center, New York, New York 10029, USA
    Semin Liver Dis 29:233-7. 2009
  5. ncbi request reprint Plasma cell hepatitis in hepatitis C virus patients post-liver transplantation: case-control study showing poor outcome and predictive features in the liver explant
    Stephen C Ward
    Lillian and Henry M Stratton Hans Popper Department of Pathology, Recanati Miller Transplantation Institute, Mount Sinai Medical Center, New York, NY 10029, USA
    Liver Transpl 15:1826-33. 2009
  6. pmc Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib
    Anja Lachenmayer
    Mount Sinai Liver Cancer Program, Mount Sinai School of Medicine, New York, NY 10029, USA
    Clin Cancer Res 18:4997-5007. 2012
  7. ncbi request reprint A single nucleotide polymorphism of Toll-like receptor 4 identifies the risk of developing graft failure after liver transplantation
    Navdeep Dhillon
    Division of Nephrology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Hepatol 53:67-72. 2010
  8. pmc Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib
    Anja Lachenmayer
    Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, New York, NY 10029, USA
    J Hepatol 56:1343-50. 2012
  9. pmc Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver
    Yongke Lu
    Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Alcohol 47:353-7. 2013
  10. ncbi request reprint Argininosuccinate synthase conditions the response to acute and chronic ethanol-induced liver injury in mice
    Tung Ming Leung
    Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Hepatology 55:1596-609. 2012

Collaborators

Detail Information

Publications26

  1. doi request reprint Hepatic progenitor cells in liver cancers from Asian children
    Stephen C Ward
    Department of Pathology, The Mount Sinai Medical Center, New York, NY 10029, USA
    Liver Int 30:102-11. 2010
    ..Hepatic progenitor cells have been described and can be stained with K19, EpCAM and CD117. We investigated the morphology and staining patterns of primary liver tumours in Asian children...
  2. ncbi request reprint Multifocal hepatocellular carcinoma and precancerous lesions in a patient with autoimmune hepatitis-related cirrhosis
    Stephen C Ward
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, The Mount Sinai Medical Center, New York, New York 10029, USA
    Semin Liver Dis 28:123-7. 2008
    ..We believe this to be the first case in the English literature documenting the presence of preneoplastic lesions in an HCV-negative patient with AIH who developed HCC...
  3. doi request reprint Fibrolamellar carcinoma: a review with focus on genetics and comparison to other malignant primary liver tumors
    Stephen C Ward
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, Mount Sinai School of Medicine, New York, USA
    Semin Liver Dis 31:61-70. 2011
    ..These features make more aggressive surgical therapy possible. There is currently very little information on the effectiveness of chemotherapy for fibrolamellar carcinoma...
  4. doi request reprint Patient with hepatitis B and alcoholic liver disease before and after liver transplantation
    Stephen C Ward
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, The Mount Sinai Medical Center, New York, New York 10029, USA
    Semin Liver Dis 29:233-7. 2009
    ..We discuss the interaction of alcoholic liver disease and hepatitis B virus in the development of cirrhosis and hepatocellular carcinoma, as well as the role of liver transplantation in these patients...
  5. ncbi request reprint Plasma cell hepatitis in hepatitis C virus patients post-liver transplantation: case-control study showing poor outcome and predictive features in the liver explant
    Stephen C Ward
    Lillian and Henry M Stratton Hans Popper Department of Pathology, Recanati Miller Transplantation Institute, Mount Sinai Medical Center, New York, NY 10029, USA
    Liver Transpl 15:1826-33. 2009
    ..The association of significant plasma cell infiltrates in native livers of HCV patients developing PCH suggests that some patients may have a predisposition to developing PCH...
  6. pmc Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib
    Anja Lachenmayer
    Mount Sinai Liver Cancer Program, Mount Sinai School of Medicine, New York, NY 10029, USA
    Clin Cancer Res 18:4997-5007. 2012
    ..We aimed to characterize Wnt-pathway aberrations in HCC patients, and to investigate sorafenib as a potential Wnt modulator in experimental models of liver cancer...
  7. ncbi request reprint A single nucleotide polymorphism of Toll-like receptor 4 identifies the risk of developing graft failure after liver transplantation
    Navdeep Dhillon
    Division of Nephrology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Hepatol 53:67-72. 2010
    ..The TLR4 single nucleotide polymorphism (SNP) D299G is situated within the extracellular domain and diminishes receptor binding to danger-associated molecular patterns...
  8. pmc Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib
    Anja Lachenmayer
    Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, New York, NY 10029, USA
    J Hepatol 56:1343-50. 2012
    ..We analyzed the expression of 11 HDACs in human HCCs and assessed the efficacy of the pan-HDAC inhibitor panobinostat alone and in combination with sorafenib in preclinical models of liver cancer...
  9. pmc Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver
    Yongke Lu
    Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Alcohol 47:353-7. 2013
    ..Tobacco smoke increases alcoholic steatosis in apoE(-/-) mice. Tobacco smoke contains more than 4000 chemicals, but it is unknown which compounds in tobacco smoke play a major role in increasing alcoholic steatosis...
  10. ncbi request reprint Argininosuccinate synthase conditions the response to acute and chronic ethanol-induced liver injury in mice
    Tung Ming Leung
    Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Hepatology 55:1596-609. 2012
    ....
  11. ncbi request reprint A case of quadruple viral infections and elevated aminotransferase activities
    Devina Bhasin
    Division of Liver Diseases and Recanati Miller Transplant Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    Semin Liver Dis 32:262-6. 2012
    ..HDV infection should be considered in patients with known chronic viral hepatitis B with low viral load, who present with worsening liver function or elevation in aminotransferase activities...
  12. pmc Morphologic features of extrahepatic manifestations of hepatitis C virus infection
    Huaibin M Ko
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Clin Dev Immunol 2012:740138. 2012
    ..This paper highlights the histomorphologic features of these processes, which are typically characterized by chronic inflammation, immune complex deposition, and immunoproliferative disease in the affected organ...
  13. doi request reprint Hepatocellular carcinoma in chronic hepatitis C in the absence of advanced fibrosis or cirrhosis
    Sara Lewis
    Department of Radiology Body MRI and Translational and Molecular Imaging Institute, Ichan School of Medicine at Mount Sinai, One Gustave Levy Pl, Box 1234, New York, NY 10029, USA
    AJR Am J Roentgenol 200:W610-6. 2013
    ..The objective of our study was to describe the cross-sectional imaging appearance of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C virus (HCV) infection in the absence of advanced fibrosis and cirrhosis...
  14. doi request reprint Complement component C3 allotypes and outcomes in liver transplantation
    Navdeep Dhillon
    Division of Nephrology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Liver Transpl 16:198-203. 2010
    ..13 (P = 0.60), 0.99 (P = 0.97), and 1.02 (P = 0.95), respectively. In conclusion, donor and recipient C3 genotypes are not associated with liver transplantation outcomes...
  15. ncbi request reprint Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation
    Stephen C Ward
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:1180-90. 2010
    ..On the basis of immunohistochemistry, fibrolamellar carcinoma seems to show both hepatocellular and bile duct differentiation...
  16. doi request reprint Primary hepatic signet ring cell neuroendocrine tumor: a case report with literature review
    Hongfa Zhu
    The Lillian and Henry M Stratton Hans Popper Department of Pathology, The Mount Sinai Medical Center, New York, NY, USA
    Semin Liver Dis 30:422-8. 2010
    ..Ten months after surgery, the patient is well without any other detectable tumor on radiology. Serological neuroendocrine markers are also within normal limits...
  17. pmc Ethanol plus the Jo2 Fas agonistic antibody-induced liver injury is attenuated in mice with partial ablation of argininosuccinate synthase
    Yongke Lu
    Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
    Alcohol Clin Exp Res 38:649-56. 2014
    ..Thus, ASS conditions NO· synthesis by NOS2. Because of the relevance of NOS2 activation for liver injury, we examined the contribution of ASS to NO· generation and how it impacts liver injury...
  18. doi request reprint Clinical and prognostic features of rectal neuroendocrine tumors
    Brett Weinstock
    Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, N Y, USA
    Neuroendocrinology 98:180-7. 2013
    ..The aim was to validate European Neuroendocrine Tumor Society (ENETS)/North American Neuroendocrine Tumor Society (NANETS) staging and grading systems with regard to clinical outcomes...
  19. doi request reprint A case of undulating fevers and elevated liver tests after pancreas-kidney transplantation
    Gene Y Im
    Division of Liver Diseases, Department of Medicine, The Mount Sinai Medical Center, New York, New York 10029 6574, USA
    Semin Liver Dis 33:89-93. 2013
    ....
  20. ncbi request reprint Precancerous lesions in inflammatory bowel disease
    Noam Harpaz
    Department of Pathology, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA
    Best Pract Res Clin Gastroenterol 27:257-67. 2013
    ....
  21. pmc Resection of nonalcoholic steatohepatitis-associated hepatocellular carcinoma: a Western experience
    Brian Shrager
    Division of Surgical Oncology, Department of Surgery, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1259, New York, NY 10029, USA
    Int J Surg Oncol 2012:915128. 2012
    ..Conclusion. Hepatocellular carcinoma may arise in the context of nonalcoholic steatohepatitis, often before cirrhosis has developed. Locally advanced tumors are typical, and long-term failure rate following resection is high...
  22. pmc Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress
    Yongke Lu
    Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Physiol Gastrointest Liver Physiol 302:G287-95. 2012
    ..Partial Ass ablation prevents pyrazole plus LPS-mediated liver injury by reducing nitrosative stress, TNFα, apoptosis, and neutrophil infiltration...
  23. pmc Successful split liver-kidney transplant for factor H associated hemolytic uremic syndrome
    Jeffrey M Saland
    Department of Pediatrics, The Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Clin J Am Soc Nephrol 4:201-6. 2009
    ..A male infant with a family history of thrombotic microangiopathy developed atypical hemolytic uremic syndrome (aHUS)...
  24. pmc MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a
    Sara Toffanin
    Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, New York, New York, USA
    Gastroenterology 140:1618-28.e16. 2011
    ..MicroRNAs (miRNAs) are involved in HCC pathogenesis, and their expression profiles have been used to classify cancers. We analyzed miRNA expression in human HCC samples to identify molecular subclasses and oncogenic miRNAs...
  25. ncbi request reprint Cholestatic liver injury associated with whey protein and creatine supplements
    Kerry N Whitt
    Department of Medicine, Division of Liver Diseases, The Mount Sinai Medical Center, New York, NY 10029, USA
    Semin Liver Dis 28:226-31. 2008
    ..We describe a case of profound jaundice related to a commonly used and reportedly safe combination of such supplements...
  26. doi request reprint Budd-Chiari syndrome in sarcoidosis involving liver
    Kemal Deniz
    Liver Int 28:580-1. 2008