Research Topics
Genomes and Genes
| Susan L TeitelbaumSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
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Publications
Associations between phthalate metabolite urinary concentrations and body size measures in New York City childrenSusan L Teitelbaum
Mount Sinai School of Medicine, Department of Preventive Medicine, One Gustave L Levy Place, Box 1057, NY 10029, USA
Environ Res 112:186-93. 2012..To examine prospectively associations between urinary phthalate metabolite concentrations and body size measures in children...
Occupation and breast cancer in women 20-44 years of age (United States)Susan L Teitelbaum
Division of Environmental Health Science, Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
Cancer Causes Control 14:627-37. 2003..To examine the relation between breast cancer risk and job history among women 20-44 years of age who participated in a multi-center, population-based, case-control study...- Reported residential pesticide use and breast cancer risk on Long Island, New YorkSusan L Teitelbaum
Department of Community Medicine, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
Am J Epidemiol 165:643-51. 2007..This study is the first known to suggest that self-reported use of residential pesticides may increase breast cancer risk. Further investigation in other populations is necessary to confirm these findings... - Questionnaire assessment of nonoccupational pesticide exposure in epidemiologic studies of cancerSusan L Teitelbaum
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
J Expo Anal Environ Epidemiol 12:373-80. 2002..Issues of exposure assessment that will be reviewed include specificity, recall, and characteristics of pesticide exposure. Additionally, sources of nonoccupational pesticide exposure other than residential will be briefly reviewed... - Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United StatesS L Teitelbaum
Mount Sinai School of Medicine, Department of Community and Preventive Medicine, 1 Gustave Levy Place, P O Box 1043, New York, NY 10029, USA
Environ Res 106:257-69. 2008..However, reliability in the use of these biomarkers requires an understanding of the timeframe of exposure represented by one measurement. Data on the temporal variability of ED biomarkers are sparse, especially among children... - Genetic polymorphisms in the apoptosis-associated genes FAS and FASL and breast cancer riskKatherine D Crew
Department of Medicine and the Herbert Irving Comprehensive Cancer Center, Columbia University, 161 Fort Washington Avenue, 10 1072, New York, NY 10032, USA
Carcinogenesis 28:2548-51. 2007..Overall, this study suggests that the risk of breast cancer may be elevated among women with polymorphisms in the FAS gene and detectable PAH-DNA adducts... - MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer riskJing Shen
Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
Carcinogenesis 26:2131-7. 2005.... - A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin usersXinran Xu
Departments of Community and Preventive Medicine and Epidemiology and Medicine, Columbia University, New York, NY, USA
Am J Clin Nutr 85:1098-102. 2007..Folic acid from multivitamins needs to be reduced by DHFR before it participates in cellular reactions... - IGHMBP2 Thr671Ala polymorphism might be a modifier for the effects of cigarette smoking and PAH-DNA adducts to breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
Breast Cancer Res Treat 99:1-7. 2006..Additional studies focused on the biological function of the variant-G allele and interactions with other genetic polymorphisms are necessary to confirm our findings... - B-vitamin intake, one-carbon metabolism, and survival in a population-based study of women with breast cancerXinran Xu
Department of Community and Preventive Medicine, Box 1043, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
Cancer Epidemiol Biomarkers Prev 17:2109-16. 2008..Our results indicate that one-carbon metabolism may be an important pathway that could be targeted to improve breast cancer survival... - Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer riskKatherine D Crew
Department of Epidemiology, Mailman School of Public Health, Columbia University, 161 Fort Washington Avenue, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 16:2033-41. 2007..Overall, this study suggests that the risk of breast cancer may be elevated among women with polymorphisms in NER pathway genes and detectable PAH-DNA adducts... 
Estrogen-biosynthesis gene CYP17 and its interactions with reproductive, hormonal and lifestyle factors in breast cancer risk: results from the Long Island Breast Cancer Study ProjectYu Chen
Department of Environmental Medicine and New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
Carcinogenesis 29:766-71. 2008..In conclusion, the findings suggest that the CYP17 variant C allele may increase breast cancer risk in conjunction with long-term HRT use and high BMI in postmenopausal women...- Polymorphism in the DNA repair gene XPD, polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, and breast cancer riskMary Beth Terry
Department of Epidemiology, Mailman School of Public Health, Columbia University, PH 18 102, 600 West 168th Street, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 13:2053-8. 2004..Overall, this study suggests that those individuals with this polymorphism in the XPD gene may face an increased risk of breast cancer from PAH-DNA adducts and cigarette smoking... - OGG1 polymorphisms and breast cancer riskPavel Rossner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
Cancer Epidemiol Biomarkers Prev 15:811-5. 2006..In addition, data on functionality of these polymorphisms are crucial to understand if these modest differences are important... - High intakes of choline and betaine reduce breast cancer mortality in a population-based studyXinran Xu
Department of Community and Preventive Medicine, Box 1057, Mt Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
FASEB J 23:4022-8. 2009..Our study supports the important roles of choline and betaine in breast carcinogenesis. It suggests that high intake of these nutrients may be a promising strategy to prevent the development of breast cancer and to reduce its mortality... - Multiple genetic variants in telomere pathway genes and breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, P and S 19 418, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 19:219-28. 2010..To explore the etiologic role of genetic variants in telomere pathway genes and breast cancer risk... - Xeroderma pigmentosum complementation group C genotypes/diplotypes play no independent or interaction role with polycyclic aromatic hydrocarbons-DNA adducts for breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, P and S 19 418, New York, NY 10032, USA
Eur J Cancer 44:710-7. 2008..69). These data suggest that XPCs have neither independent effects nor interactions with cigarette smoking and PAH-DNA adducts for breast cancer risk. Further studies with multiple genetic polymorphisms in NER pathway are warranted... - Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 14:336-42. 2005..Further understanding of the biological function of XRCC1 variants and their interactions with PAH-DNA adducts, antioxidants, and other genes in the pathway are needed... - Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based studyXinran Xu
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
Carcinogenesis 28:1504-9. 2007..Although the pathway is a network of interrelated enzymes, redundancy exists; evaluating the rate-limiting enzyme and its interaction with environment and other genes within the same pathway is critical in assessing breast cancer risk... - Improving organochlorine biomarker models for cancer researchMary S Wolff
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
Cancer Epidemiol Biomarkers Prev 14:2224-36. 2005..e., PCB) or long discontinued (i.e., DDE)... - Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, New York, New York 10032, USA
Breast Cancer Res 8:R71. 2006..926, COX-2 .5209, and COX-2 .8473) may reduce overall breast cancer risk or risk for subtypes of breast cancer by modulating the inflammatory response and may interact with aspirin or any NSAID use... - A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer riskKathryn E Talbott
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA
Breast Cancer Res Treat 111:481-7. 2008..The finding supports the potential role of variation in estrogen biosynthesis genes in premenopausal breast cancer risk... - Association between plasma 25-hydroxyvitamin D and breast cancer riskKatherine D Crew
Department of Medicine, Division of Hematology Oncology, Columbia University, New York, New York 10032, USA
Cancer Prev Res (Phila) 2:598-604. 2009..Well-designed clinical trials are urgently needed to determine whether vitamin D supplementation is effective for breast cancer chemoprevention... - Plasma protein carbonyl levels and breast cancer riskPavel Rossner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
J Cell Mol Med 11:1138-48. 2007..8, 95% CI = 1.2-2.6) compared to women with levels below the median for both markers of oxidative stress. In summary, our results suggest that increased plasma protein carbonyl levels may be associated with breast cancer risk... - Choline metabolism and risk of breast cancer in a population-based studyXinran Xu
Department of Community and Preventive Medicine, Mt Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
FASEB J 22:2045-52. 2008..We observed a significant interaction between dietary betaine intake and the PEMT rs7926 polymorphism (P(interaction)=0.04). Our findings suggest that choline metabolism may play an important role in breast cancer etiology... - Telomere length, oxidative damage, antioxidants and breast cancer riskJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Int J Cancer 124:1637-43. 2009..01). These results provided the strongest evidence to date that breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements... - ADH3 genotype, alcohol intake and breast cancer riskMary Beth Terry
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA, and Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
Carcinogenesis 27:840-7. 2006..9, 95 % CI=1.2-7.1; postmenopausal women OR=1.8, 95% CI=0.9-3.8). These population-based data support the hypothesis that fast metabolizers of alcohol have a higher risk of breast cancer risk, from alcohol intake than slow metabolizers... - Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survivalJing Shen
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 650 West 168th Street, Black Building 1608, New York, NY 10032, USA
Breast Cancer Res Treat 134:393-400. 2012..These data suggest that unfavorable genetic variants in telomere pathway genes may help to predict breast cancer survival... - Prognostic significance of gene-specific promoter hypermethylation in breast cancer patientsYoon Hee Cho
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th St, New York, NY 10032, USA
Breast Cancer Res Treat 131:197-205. 2012..002), although confidence intervals were wide. Our results suggest that promoter methylation, particularly for a panel of genes, has the potential to be used as a biomarker for predicting prognosis in breast cancer... - Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohortStephanie M Engel
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
Am J Epidemiol 165:1397-404. 2007..The authors uncovered additional evidence that prenatal levels of organophosphate pesticide metabolites are associated with anomalies in primitive reflexes, which are a critical marker of neurologic integrity... - One-carbon metabolism, MTHFR polymorphisms, and risk of breast cancerJia Chen
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York, USA
Cancer Res 65:1606-14. 2005..96) or total folate intake (OR, 1.71; 95% CI, 1.08-2.71). From a public heath perspective, it is important to identify risk factors, such as low B vitamin consumption, that may guide an effective prevention strategy against the disease... - Prevalence and predictors of antioxidant supplement use during breast cancer treatment: the Long Island Breast Cancer Study ProjectHeather Greenlee
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Cancer 115:3271-82. 2009..The authors of this report analyzed the prevalence of and factors associated with antioxidant supplement use during breast cancer (BC) treatment among women who participated in the Long Island Breast Cancer Study Project... - Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer riskJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, New York, USA
Cancer Res 64:7634-9. 2004.... - Gene promoter methylation is associated with increased mortality among women with breast cancerXinran Xu
Department of Preventive Medicine, Mount Sinai School of Medicine, New York, NY, USA
Breast Cancer Res Treat 121:685-92. 2010..Our results suggest that promoter methylation could be promising epigenetic markers to be considered for breast cancer survival... - Body size changes in relation to postmenopausal breast cancer among women on Long Island, New YorkSybil M Eng
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10017, USA
Am J Epidemiol 162:229-37. 2005..55, 95% CI: 0.32, 0.96). These results add to the literature by focusing on the perimenopausal weight trajectory and support efforts urging women to avoid weight gain as they age... - Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer riskPavel Rossner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 15:639-44. 2006..In summary, our results suggest that urinary markers of lipid peroxidation and oxidative DNA damage may be associated with breast cancer risk... - Investigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girlsMary S Wolff
Mount Sinai School of Medicine, New York, NY 10029, USA
Environ Health Perspect 118:1039-46. 2010..Hormonally active environmental agents may alter the course of pubertal development in girls, which is controlled by steroids and gonadotropins... - Preeclampsia, pregnancy-related hypertension, and breast cancer riskMary Beth Terry
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Am J Epidemiol 165:1007-14. 2007..These data suggest that pregnancy conditions related to hypertension, particularly preeclampsia, play a role in reducing breast cancer risk. Possible biologic mechanisms underpinning these associations should be further explored... - Mutations in p53, p53 protein overexpression and breast cancer survivalPavel Rossner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
J Cell Mol Med 13:3847-57. 2009.... - Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girlsMary S Wolff
Mount Sinai School of Medicine, Division of Environmental Health Sciences, Department of Community and Preventive Medicine, New York, New York 10029, USA
Environ Health Perspect 115:116-21. 2007..S. children using exposure biomarkers in urine. However, little is known about their variation by race, age, sex, and geography, and no data exist for newly developed biomarkers... - Temporal variability in urinary concentrations of perchlorate, nitrate, thiocyanate and iodide among childrenNancy Mervish
Department of Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
J Expo Sci Environ Epidemiol 22:212-8. 2012..Surrogate analysis show that single-spot urine samples reliably categorize participant's exposure providing support for the use of a single sample as an exposure measure in epidemiological studies that use relative ranking of exposure... - Lifetime alcohol intake and breast cancer riskMary Beth Terry
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Ann Epidemiol 16:230-40. 2006..Risk is confined to moderate intake and does not vary with the timing of use, with heavier doses, or with the type of alcohol consumed... - BRCA1 promoter methylation is associated with increased mortality among women with breast cancerXinran Xu
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, P O Box 1043, One Gustave L Levy Place, New York, NY 10029, USA
Breast Cancer Res Treat 115:397-404. 2009..Our results indicate that BRCA1 promoter methylation is an important factor to consider in predicting breast cancer survival... - DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based studyXinran Xu
Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
FASEB J 26:2657-66. 2012..018). LINE-1 methylation was associated with neither breast cancer risk nor 1-carbon metabolism. Our results show that global promoter hypermethylation measured in peripheral blood was associated with breast cancer risk... - Estrogen metabolism and breast cancerGeoffrey C Kabat
Department of Preventive Medicine, School of Medicine, Stony Brook University, New York, USA
Epidemiology 17:80-8. 2006.... - Exposures among pregnant women near the World Trade Center site on 11 September 2001Mary S Wolff
Mount Sinai School of Medicine, New York, New York 10029, USA
Environ Health Perspect 113:739-48. 2005..This report indicates intense bystander exposure after the WTC collapse and provides information about nonoccupational exposures among a vulnerable population of pregnant women... - Electric blanket use and breast cancer on Long IslandGeoffrey C Kabat
Department of Preventive Medicine, School of Medicine, Stony Brook University, Stony Brook, NY, USA
Epidemiology 14:514-20. 2003..CONCLUSIONS: The results of this large investigation are consistent with those of most previous studies, and do not support the hypothesis that electric blanket use is associated with increased breast cancer risk... - Association of frequency and duration of aspirin use and hormone receptor status with breast cancer riskMary Beth Terry
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
JAMA 291:2433-40. 2004..67-1.40). CONCLUSION: These data add to the growing evidence that supports the regular use of aspirin and other NSAIDs (which may operate through inhibition of estrogen biosynthesis) as effective chemopreventive agents for breast cancer... - Influence of prediagnostic recreational physical activity on survival from breast cancerRebecca J Cleveland
Department of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7280, USA
Eur J Cancer Prev 21:46-54. 2012..no RPA, the HR=0.61; 95% CI=0.39-0.94 and HR=1.00; 95% CI=0.65-1.54, respectively). This study provides support that RPA prior to breast cancer diagnosis improves survival... - Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancerJonine L Bernstein
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
Hum Mutat 21:542-50. 2003..Finally, we report novel mutations in the ATM gene identified both in patients with ataxia-telangiectasia and in patients with unilateral or bilateral breast cancer... - ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancerJ L Bernstein
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1043, New York, NY 10029 6574, USA
Br J Cancer 89:1513-6. 2003.... - Associations between neighborhood resources and physical activity in inner-city minority childrenMaida P Galvez
Department of Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10023, USA
Acad Pediatr 13:20-6. 2013..We describe how availability of physical activity resources varies by individual and block characteristics and then examine its associations with physical activity levels of Latino and black children in East Harlem, New York City... - Measures of obesity associated with asthma diagnosis in ethnic minority childrenNita Vangeepuram
Department of Preventive Medicine, Mount Sinai School of Medicine, 1 Gustave L Levy Place, Box 1512, New York, NY 10029, USA
J Obes 2011:517417. 2011..63 (95% CI 1.12-2.39), 1.50 (95% CI 1.02-2.21), and 1.56 (95% CI 1.04-2.34), resp.). Conclusions. This study found a significant association between increased body size and asthma diagnosis, regardless of the measurement examined... - Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE studyJonine L Bernstein
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY, USA
Breast Cancer Res 6:R199-214. 2004..Three genes (ATM, BRCA1, and BRCA2) encode products that are essential for the normal cellular response to DSBs, but predispose to breast cancer when mutated... - Persistence of multiple illnesses in World Trade Center rescue and recovery workers: a cohort studyJuan P Wisnivesky
Divisions of General Internal Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
Lancet 378:888-97. 2011..We report incidence and prevalence rates of physical and mental health disorders during the 9 years since the attacks, examine their associations with occupational exposures, and quantify physical and mental health comorbidities... - Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smokeBeatrice Faraglia
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street, New York, NY 10032, USA
Carcinogenesis 24:719-25. 2003..In this study, genetic polymorphisms did not significantly affect the formation of 4-ABP-DNA adducts in breast cancer cases, perhaps due to the small number of samples... - Mice deficient in Abl are osteoporotic and have defects in osteoblast maturationB Li
Howard Hughes Medical Institute, Columbia University, College of Physicians and Surgeons, New York, New York, USA
Nat Genet 24:304-8. 2000..Osteoblasts from both stromal and calvarial explants showed delayed maturation in vitro as measured by expression of alkaline phosphatase (ALP), induction of mRNA encoding osteocalcin and mineral deposition... - The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancerMarilie D Gammon
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599 7400, USA
Breast Cancer Res Treat 74:235-54. 2002.... - Environmental toxins and breast cancer on Long Island. II. Organochlorine compound levels in bloodMarilie D Gammon
Department of Epidemiology, University of North Carolina, School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
Cancer Epidemiol Biomarkers Prev 11:686-97. 2002..These findings, based on the largest number of samples analyzed to date among primarily white women, do not support the hypothesis that organochlorines increase breast cancer risk among Long Island women... - Genetic variation of TP53, polycyclic aromatic hydrocarbon-related exposures, and breast cancer risk among women on Long Island, New YorkMia M Gaudet
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Breast Cancer Res Treat 108:93-9. 2008..p53 participates in cell cycle control, programmed cell death/apoptosis, and DNA repair, all pathways involved in carcinogenesis. TP53 variants may influence p53 function... - Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adductsMarilie D Gammon
Department of Epidemiology, University of North Carolina, School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
Cancer Epidemiol Biomarkers Prev 11:677-85. 2002..These data indicate that PAH-DNA adduct formation may influence breast cancer development, although the association does not appear to be dose dependent and may have a threshold effect... - Environmental tobacco smoke and breast cancer incidenceMarilie D Gammon
Department of Epidemiology, School of Public Health, University of North Carolina, CB 7435 McGavern Greenberg Hall, Chapel Hill, NC 27599 7435, USA
Environ Res 96:176-85. 2004..42 for ER+ PR+, 95% CI, 1.00, 2.00). Our data suggest that if there is an effect for ETS on breast cancer, that effect is restricted to selected subgroups of women, such as those with long-term exposure from a smoking spouse... - Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor statusMia M Gaudet
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
Cancer Epidemiol Biomarkers Prev 13:1485-94. 2004..Our results support an inverse association for fruit and vegetable intake among postmenopausal but not premenopausal breast cancer, which may be more pronounced among women with ER+ tumors... - Residential environmental exposures and other characteristics associated with detectable PAH-DNA adducts in peripheral mononuclear cells in a population-based sample of adult femalesSumitra Shantakumar
Department of Epidemiology, CB 7435 McGavran Greenberg Hall, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
J Expo Anal Environ Epidemiol 15:482-90. 2005..These data suggest that PAH-DNA adducts detected in a population-based sample of adult women with ambient exposure levels reflect some key residential PAH exposure sources assessed in this study, such as cigarette smoking... - Peroxisome proliferator-activated receptor-alpha (PPARA) genetic polymorphisms and breast cancer risk: a Long Island ancillary studyAmanda K Golembesky
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599, USA
Carcinogenesis 29:1944-9. 2008..Our results are the first to evaluate the relationship between PPARA and breast cancer incidence and suggest that replication in an independent cohort is warranted... - Active and passive cigarette smoke and breast cancer survivalSharon K Sagiv
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Ann Epidemiol 17:385-93. 2007..The association between active and passive cigarette smoking before breast cancer diagnosis and survival was investigated among a cohort of invasive breast cancer cases (n = 1273) participating in a population-based case-control study... - Dietary flavonoid intake and breast cancer risk among women on Long IslandBrian N Fink
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Am J Epidemiol 165:514-23. 2007..These results suggest that US women can consume sufficient levels of flavonoids to benefit from their potential chemopreventive effects... - Cooked meat and risk of breast cancer--lifetime versus recent dietary intakeSusan E Steck
Department of Nutrition, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Epidemiology 18:373-82. 2007..Polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HCAs) are carcinogens formed in or on the surface of well-done meat, cooked at high temperature... - Weight gain prior to diagnosis and survival from breast cancerRebecca J Cleveland
Department of Epidemiology, University of North Carolina, CB 7435 McGavran Greenberg Hall, Chapel Hill, NC 27599 7435, USA
Cancer Epidemiol Biomarkers Prev 16:1803-11. 2007.... - Validation and calibration of a model used to reconstruct historical exposure to polycyclic aromatic hydrocarbons for use in epidemiologic studiesJan Beyea
Consulting in the Public Interest, Lambertville, New Jersey, USA
Environ Health Perspect 114:1053-8. 2006..Here we report the results of four exercises to validate and calibrate the model... - Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysisMarilie D Gammon
Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
Arch Environ Health 59:640-9. 2004..These data provide only modest support for an association between PAH-DNA adducts and breast cancer development... - Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer riskJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Carcinogenesis 27:1876-82. 2006..These data indicate that GSTA1 genotypes related to reduced GSTA1 expression are associated with increased breast cancer primarily among women with lower consumption of cruciferous vegetables and among current smokers... - MnSOD Val-9Ala genotype, pro- and anti-oxidant environmental modifiers, and breast cancer among women on Long Island, New YorkMia M Gaudet
Department of Epidemiology, School of Public Health, University of North Carolina, CB 7435, Chapel Hill, NC 27599 7435, USA
Cancer Causes Control 16:1225-34. 2005..This study provides little evidence that variation in Val-9Ala polymorphism of MnSOD alone or through substantial interaction with key exposures believed to be pro- or anti-oxidant properties influences breast cancer risk... - Catechol-O-methyltransferase haplotypes and breast cancer among women on Long Island, New YorkMia M Gaudet
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hil, NC 27516, USA
Breast Cancer Res Treat 99:235-40. 2006.... - IGF1 CA repeat polymorphisms, lifestyle factors and breast cancer risk in the Long Island Breast Cancer Study ProjectRebecca J Cleveland
Department of Epidemiology, School of Public Health and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Carcinogenesis 27:758-65. 2006..Our results demonstrate a role for alleles with fewer than (CA)19 repeats as a risk factor for breast cancer and also suggest that several traditional breast cancer risk factors modify the association of the IGF1 (CA)19 repeat genotype... - Dietary flavonoid intake and breast cancer survival among women on Long IslandBrian N Fink
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA
Cancer Epidemiol Biomarkers Prev 16:2285-92. 2007..However, the effects of flavonoids on survival are not known. In a population-based cohort of breast cancer patients, we investigated whether dietary flavonoid intake before diagnosis is associated with subsequent survival... - Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement useJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Am J Epidemiol 162:943-52. 2005..CC genotypes were prevalent in approximately 64% of controls; thus, the preventive potential for fruit consumption has widespread implications... - No association between glutathione peroxidase Pro198Leu polymorphism and breast cancer riskJiyoung Ahn
Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Cancer Epidemiol Biomarkers Prev 14:2459-61. 2005 - Reproductive factors and breast cancer risk among older womenSumitra Shantakumar
Department of Epidemiology, CB 7435 McGavran Greenberg Hall, University of North Carolina School of Public Health, Chapel Hill, NC 27599 7435, USA
Breast Cancer Res Treat 102:365-74. 2007..Moreover, breastfeeding, one of the few potentially modifiable risk factors for breast cancer, was an important factor in decreasing risk among older parous postmenopausal women... - Correspondence re: Schoen et al., Lack of association between adipose tissue distribution, and insulin-like growth factor-I and insulin-like growth factor binding protein-3 in men and women. Cancer Epidemiol. Biomark. Prev., 11: 581-586, 2002Julie A Britton
Cancer Epidemiol Biomarkers Prev 12:586; author reply 586-7. 2003 - Fruits, vegetables, and micronutrient intake in relation to breast cancer survivalBrian N Fink
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Breast Cancer Res Treat 98:199-208. 2006..To determine whether fruit, vegetable, and micronutrient intake 1 year prior to breast cancer diagnosis is associated with a reduction in the subsequent risk of all-cause or breast cancer-specific mortality... - Age and menopausal effects of hormonal birth control and hormone replacement therapy in relation to breast cancer riskSumitra Shantakumar
Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, NC, USA
Am J Epidemiol 165:1187-98. 2007..These results emphasize that timing of exogenous hormone use is important. Women who used these hormones before menopause had elevated risks, but the harmful effects began to decline with age after menopause...
Research Grants
- Molecular Epidemiology of Xenoestrogen ExposureSusan Teitelbaum; Fiscal Year: 2007..Furthermore, data analysis approaches applied in this research project will be applicable to a wide range of environmentally associated diseases. ..