Affiliation: Mount Sinai School of Medicine
Country: USA


  1. Kurowski A, Molotkov A, Soriano P. FGFR1 regulates trophectoderm development and facilitates blastocyst implantation. Dev Biol. 2018;: pubmed publisher
    ..These results suggest that while the TE is specified in Fgfr1-/- mutants, its differentiation abilities are compromised leading to defects at implantation. ..
  2. Molotkov A, Soriano P. Distinct mechanisms for PDGF and FGF signaling in primitive endoderm development. Dev Biol. 2018;442:155-161 pubmed publisher
    ..Together, these studies indicate how multiple growth factors and signaling pathways can cooperate in preimplantation development. ..
  3. Vasudevan H, Soriano P. A Thousand and One Receptor Tyrosine Kinases: Wherein the Specificity?. Curr Top Dev Biol. 2016;117:393-404 pubmed publisher
  4. Dinsmore C, Soriano P. MAPK and PI3K signaling: At the crossroads of neural crest development. Dev Biol. 2018;: pubmed publisher
    ..This review summarizes our current understanding of growth factor-induced MAPK and PI3K signaling in the neural crest. ..
  5. Vasudevan H, Soriano P. SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling. Dev Cell. 2014;31:332-44 pubmed publisher
  6. Molotkov A, Mazot P, Brewer J, Cinalli R, Soriano P. Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency. Dev Cell. 2017;41:511-526.e4 pubmed publisher
    ..Collectively, these results identify mechanisms through which FGF signaling regulates inner cell mass lineage restriction and cell commitment during preimplantation development. ..
  7. He F, Soriano P. Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification. Development. 2017;144:4026-4036 pubmed publisher
    ..Our results thus identify a novel mechanism underlying calvarial development in craniosynostosis. ..