Leo Sher

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. doi request reprint Testosterone levels in suicide attempters with bipolar disorder
    Leo Sher
    New York State Psychiatric Institute and Columbia University College of Physicians and Surgeons, New York, NY 10468, USA
    J Psychiatr Res 46:1267-71. 2012
  2. doi request reprint Teaching medical professionals and trainees about adolescent suicide prevention: five key problems
    Leo Sher
    Mount Sinai School of Medicine, James J Peters Veterans Administration Medical Center, NY, USA
    Int J Adolesc Med Health 24:121-3. 2012
  3. pmc Decreased suicidal ideation in depressed patients with or without comorbid posttraumatic stress disorder treated with selective serotonin reuptake inhibitors: an open study
    Leo Sher
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Psychiatry Res 196:261-6. 2012
  4. doi request reprint Posttraumatic stress disorder, depression, and suicide in veterans
    Leo Sher
    James J Peters Veterans Administration Medical Center, Bronx, NY 10468, USA
    Cleve Clin J Med 79:92-7. 2012
  5. ncbi request reprint Teaching health care professionals about suicide safety planning
    Leo Sher
    James J Peters Veterans Administration, Medical Center, 130 West Kingsbridge Road, Bronx, New York 10468, USA
    Psychiatr Danub 23:396-7. 2011
  6. ncbi request reprint Depressed patients with co-occurring alcohol use disorders: a unique patient population
    Leo Sher
    Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 69:907-15. 2008
  7. ncbi request reprint A prospective study of the association of cerebrospinal fluid monoamine metabolite levels with lethality of suicide attempts in patients with bipolar disorder
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Bipolar Disord 8:543-50. 2006
  8. ncbi request reprint A comparison of the medical lethality of suicide attempts in bipolar and major depressive disorders
    Gil Zalsman
    Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Bipolar Disord 8:558-65. 2006
  9. ncbi request reprint Triggers for suicidal behavior in depressed older adolescents and young adults: do alcohol use disorders make a difference?
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 19:91-8. 2007
  10. pmc Family history of suicidal behavior and early traumatic experiences: additive effect on suicidality and course of bipolar illness?
    Juan J Carballo
    Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, United States
    J Affect Disord 109:57-63. 2008

Detail Information

Publications60

  1. doi request reprint Testosterone levels in suicide attempters with bipolar disorder
    Leo Sher
    New York State Psychiatric Institute and Columbia University College of Physicians and Surgeons, New York, NY 10468, USA
    J Psychiatr Res 46:1267-71. 2012
    ..This is the first study to examine whether there is a relation between testosterone levels and clinical parameters in bipolar suicide attempters...
  2. doi request reprint Teaching medical professionals and trainees about adolescent suicide prevention: five key problems
    Leo Sher
    Mount Sinai School of Medicine, James J Peters Veterans Administration Medical Center, NY, USA
    Int J Adolesc Med Health 24:121-3. 2012
    ....
  3. pmc Decreased suicidal ideation in depressed patients with or without comorbid posttraumatic stress disorder treated with selective serotonin reuptake inhibitors: an open study
    Leo Sher
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Psychiatry Res 196:261-6. 2012
    ..Our finding has not supported the hypothesis that a response to treatment is poorer in the PTSD-MDD group which may indicate that sicker patients benefit more from the treatment...
  4. doi request reprint Posttraumatic stress disorder, depression, and suicide in veterans
    Leo Sher
    James J Peters Veterans Administration Medical Center, Bronx, NY 10468, USA
    Cleve Clin J Med 79:92-7. 2012
    ..The authors discuss the association of PTSD, depression, and suicide in veterans, keys to assessment of suicide risk, and interventions...
  5. ncbi request reprint Teaching health care professionals about suicide safety planning
    Leo Sher
    James J Peters Veterans Administration, Medical Center, 130 West Kingsbridge Road, Bronx, New York 10468, USA
    Psychiatr Danub 23:396-7. 2011
    ..Although more resources are now being provided to individuals with suicidal behavior, more research needs to be done to develop new, effective methods of treatment and prevention of suicidal behavior...
  6. ncbi request reprint Depressed patients with co-occurring alcohol use disorders: a unique patient population
    Leo Sher
    Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 69:907-15. 2008
    ..Few studies have assessed the impact of comorbid alcohol use disorders (AUDs) on clinical aspects of major depression. We compared depressed subjects with and without co-occurring AUDs with respect to demographic and clinical parameters...
  7. ncbi request reprint A prospective study of the association of cerebrospinal fluid monoamine metabolite levels with lethality of suicide attempts in patients with bipolar disorder
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Bipolar Disord 8:543-50. 2006
    ....
  8. ncbi request reprint A comparison of the medical lethality of suicide attempts in bipolar and major depressive disorders
    Gil Zalsman
    Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Bipolar Disord 8:558-65. 2006
    ....
  9. ncbi request reprint Triggers for suicidal behavior in depressed older adolescents and young adults: do alcohol use disorders make a difference?
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 19:91-8. 2007
    ..We compared demographic and clinical characteristics, prevalence of interpersonal triggers and the number of triggers for suicidal behavior in depressed late adolescents and young adults with or without comorbid alcohol use disorders...
  10. pmc Family history of suicidal behavior and early traumatic experiences: additive effect on suicidality and course of bipolar illness?
    Juan J Carballo
    Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, United States
    J Affect Disord 109:57-63. 2008
    ..Bipolar disorder (BD) is associated with a high prevalence of suicide attempt and completion. Family history of suicidal behavior and personal history of childhood abuse are reported risk factors for suicide among BD subjects...
  11. ncbi request reprint Correlates of suicide attempt history in bipolar disorder: a stress-diathesis perspective
    Michael F Grunebaum
    Department of Neuroscience, New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Bipolar Disord 8:551-7. 2006
    ..We sought to identify such factors and to consider them within a stress-diathesis model of suicidal behavior...
  12. pmc Moral objections to suicide and suicidal ideation among mood disordered Whites, Blacks, and Hispanics
    Randall Richardson-Vejlgaard
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA
    J Psychiatr Res 43:360-5. 2009
    ..This study examined the MOS and suicidal ideation of White, Black, and Hispanic individuals with mood disorders. We expected minority individuals to have stronger objections to suicide...
  13. ncbi request reprint Aggression and substance abuse in bipolar disorder
    Michael F Grunebaum
    Department of Neuroscience, New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Bipolar Disord 8:496-502. 2006
    ..We also explored the chronology of onset of mood and SUD...
  14. ncbi request reprint CSF monoamine metabolites and lethality of suicide attempts in depressed patients with alcohol dependence
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Eur Neuropsychopharmacol 17:12-5. 2007
    ..We sought to study the relationship of CSF monoamine metabolites to lethality of suicidal acts in depressed subjects with comorbid alcoholism...
  15. ncbi request reprint Clinical predictors of suicidal acts after major depression in bipolar disorder: a prospective study
    Hanga Galfalvy
    Department of Neuroscience, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
    Bipolar Disord 8:586-95. 2006
    ..This study determined the clinical predictors of suicidal behavior during a 2-year follow-up of patients with bipolar disorder presenting with a major depressive episode (MDE)...
  16. ncbi request reprint Higher cerebrospinal fluid homovanillic acid levels in depressed patients with comorbid posttraumatic stress disorder
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    Eur Neuropsychopharmacol 15:203-9. 2005
    ..Higher dopaminergic activity may contribute to alterations in memory and other cognitive functions, anhedonia, and hypervigilance observed in PTSD...
  17. ncbi request reprint Pathological personality traits and suicidal ideation among older adolescents and young adults with alcohol misuse: a pilot case-control study in a primary care setting
    Juan J Carballo
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 19:79-89. 2007
    ..To compare the clinical and demographic characteristics of older adolescents and young adults with and without alcohol misuse in a primary care setting...
  18. pmc Are high-lethality suicide attempters with bipolar disorder a distinct phenotype?
    Maria A Oquendo
    Division of Molecular Imaging and Neuropathology, Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
    Arch Suicide Res 13:247-56. 2009
    ..A subset of high-lethality attempters make only high-lethality attempts. However, presence of previous low-lethality attempts does not indicate that risk for more lethal, possibly successful, attempts is reduced...
  19. ncbi request reprint Higher cortisol levels in spring and fall in patients with major depression
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Prog Neuropsychopharmacol Biol Psychiatry 29:529-34. 2005
    ..This study sought to determine whether there is a seasonal effect on clinical parameters, baseline cortisol and prolactin levels, and cortisol and prolactin responses to fenfluramine administration in subjects with major depression...
  20. pmc Effect of acute alcohol use on the lethality of suicide attempts in patients with mood disorders
    Leo Sher
    Department of Psychiatry, Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    J Psychiatr Res 43:901-5. 2009
    ..Acute alcohol use increases the lethality of suicide attempts in individuals with mood disorders...
  21. doi request reprint Is impulsivity a link between childhood abuse and suicide?
    M Dolores Braquehais
    Department of Psychiatry Columbia University, New York, NY 10032, USA
    Compr Psychiatry 51:121-9. 2010
    ..Prevention of childhood abuse could significantly reduce suicidal behavior in adolescents and adults, in part, through a decrease in the frequency of impulsive behaviors in the future...
  22. ncbi request reprint The relationship of aggression to suicidal behavior in depressed patients with a history of alcoholism
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    Addict Behav 30:1144-53. 2005
    ..The reason for higher rate of suicide and suicide attempts in comorbid subjects is uncertain. We explored clinical characteristics that may be associated with this increased suicidality...
  23. pmc Treatment of suicide attempters with bipolar disorder: a randomized clinical trial comparing lithium and valproate in the prevention of suicidal behavior
    Maria A Oquendo
    Columbia University, New York State Psychiatric Institute, New York, USA
    Am J Psychiatry 168:1050-6. 2011
    ..The authors tested the hypothesis that lithium offers bipolar patients with a history of suicide attempt greater protection against suicidal behavior compared to valproate...
  24. pmc Positron emission tomography study of regional brain metabolic responses to a serotonergic challenge in major depressive disorder with and without comorbid lifetime alcohol dependence
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Eur Neuropsychopharmacol 17:608-15. 2007
    ..The fact that the observed group difference disappeared after the fenfluramine challenge suggests that serotonergic mechanisms play a role in the observed differences between the groups...
  25. pmc Serotonergic responses in depressed patients with or without a history of alcohol use disorders and healthy controls
    Leo Sher
    Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, New York, NY 10032, USA
    Eur Neuropsychopharmacol 18:692-9. 2008
    ..The difference in prolactin responses between MDD/AUD and MDD only could be attributed to higher aggression scores in the MDD/AUD group compared to the MDD group...
  26. ncbi request reprint The role of the hypothalamic-pituitary-adrenal axis dysfunction in the pathophysiology of alcohol misuse and suicidal behavior in adolescents
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Adolesc Med Health 19:3-9. 2007
    ..Furthermore, study of biological markers may help us towards an understanding of the neurophysiological substrates of severe dysphoric mood states, alcohol and substance abuse, and suicidal behavior in adolescents...
  27. doi request reprint Adolescent suicide in New York City: plenty of room for new research
    Debora Ganz
    Ferkauf Graduate School of Psychology of Yeshiva University, New York, NY, USA
    Int J Adolesc Med Health 24:99-104. 2012
    ..This dearth of literature may be related to the ethical problems inherent in suicide research, self reports and/or post mortem analyses...
  28. ncbi request reprint The number of previous depressive episodes is positively associated with cortisol response to fenfluramine administration
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    Ann N Y Acad Sci 1032:283-6. 2004
    ..Our finding highlights the importance of possible cumulative effects of repeated episodes of major depression. Prevention and early recognition of depressive episodes may prevent these cumulative adverse effects...
  29. pmc Objections to suicide among depressed patients with alcohol use disorders
    Randall Richardson-Vejlgaard
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, United States
    J Affect Disord 117:197-201. 2009
    ..One measure of suicide non-acceptability is the Moral Objections to Suicide (MOS) subscale of the Reasons for Living Inventory (RFLI)...
  30. pmc Non-suicidal self-injurious behavior, endogenous opioids and monoamine neurotransmitters
    Barbara Stanley
    Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, New York 10032, USA
    J Affect Disord 124:134-40. 2010
    ..This behavior, particularly when there is no apparent suicidal intent, is poorly understood from both biological and clinical perspectives...
  31. ncbi request reprint Lower cerebrospinal fluid homovanillic acid levels in depressed suicide attempters
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York State Psychiatric Institute, Box 42, New York, NY 10032, USA
    J Affect Disord 90:83-9. 2006
    ....
  32. ncbi request reprint Age effects on cortisol levels in depressed patients with and without comorbid post-traumatic stress disorder, and healthy volunteers
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    J Affect Disord 82:53-9. 2004
    ..Therefore, we examined the effect of age on the hypothalamic-pituitary-adrenal (HPA) system in depressed patients with and without PTSD...
  33. ncbi request reprint Ethnicity and the relationship between adolescent alcohol use and suicidal behavior
    Shelly A Groves
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Adolesc Med Health 19:19-25. 2007
    ..Cultural differences in alcohol consumption may account for disparities, however future research is needed to further examine cultural trends in suicidal behavior and alcoholism...
  34. ncbi request reprint Lower CSF homovanillic acid levels in depressed patients with a history of alcoholism
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 28:1712-9. 2003
    ..Low CSF HVA suggests that impaired dopaminergic activity is associated with a history of alcoholism in persons with current MDE...
  35. ncbi request reprint The role of the pediatrician in preventing suicide in adolescents with alcohol use disorders
    Juan J Carballo
    Division of Child Psychiatry, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 19:61-5. 2007
    ....
  36. doi request reprint Suicidal behavior in war veterans
    Timothy R Rice
    Department of Psychiatry, The Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1230, New York, NY 10029, USA
    Expert Rev Neurother 12:611-24. 2012
    ..This critical review of the literature provides an overview of this active field of neuropsychiatric research with a select focus upon these topics of special interest...
  37. ncbi request reprint Alcohol and suicide: neurobiological and clinical aspects
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, USA
    ScientificWorldJournal 6:700-6. 2006
    ..The management of suicidal patients with alcohol use disorders is also discussed. It is to be hoped that the efforts of clinicians will reduce morbidity and mortality associated with alcohol misuse...
  38. ncbi request reprint Combined dexamethasone suppression-corticotropin-releasing hormone stimulation test in studies of depression, alcoholism, and suicidal behavior
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, USA
    ScientificWorldJournal 6:1398-404. 2006
    ..The combined DEX-CRH test may become a useful neuroendocrinological tool for evaluating psychiatric patients...
  39. pmc Perceived reasons for living at index hospitalization and future suicide attempt
    Dana Lizardi
    Columbia University School of Social Work, New York, New York 10027, USA
    J Nerv Ment Dis 195:451-5. 2007
    ..Perceived reasons for living serve as protective factors against suicide attempt in women and not in men...
  40. ncbi request reprint Functional magnetic resonance imaging in studies of the neurobiology of suicidal behavior in adolescents with alcohol use disorders
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Adolesc Med Health 19:11-8. 2007
    ....
  41. ncbi request reprint Modified dexamethasone suppression-corticotropin-releasing hormone stimulation test: A pilot study of young healthy volunteers and implications for alcoholism research in adolescents and young adults
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 18:133-7. 2006
    ..Therefore, studies of the HPA system in persons at risk for alcoholism may help understand the neurobiological mechanisms of predisposition to alcoholism...
  42. ncbi request reprint Prolactin response to fenfluramine administration in patients with unipolar and bipolar depression and healthy controls
    Leo Sher
    Department of Neuroscience, New York State Psychiatric Institute, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    Psychoneuroendocrinology 28:559-73. 2003
    ..The lack of difference in the response to fenfluramine administration between unipolar and bipolar depressed patients may indicate that overall serotonergic function in unipolar and bipolar depressed patients is similarly impaired...
  43. ncbi request reprint Alcohol use and suicide rates
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    Med Hypotheses 65:1010-2. 2005
    ..There may be a broad-based social characteristic related to social stress which is associated with high rates of a variety of stress-related behaviors, including heavy alcohol use and suicide...
  44. ncbi request reprint Alcohol use in adolescents with eating disorders
    Alexis H Conason
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 18:31-6. 2006
    ..Teaching healthy ways to cope with the stressful situations may also help decrease alcohol use and disordered eating behaviors...
  45. ncbi request reprint Psychotherapy in the treatment of alcohol and substance abusing adolescents with suicidal behavior
    Alexis H Conason
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 18:9-13. 2006
    ..Further research is needed to determine the efficacy of various treatments of alcohol and substance abusing adolescents with suicidal behavior...
  46. ncbi request reprint Risk and protective factors for suicide in patients with alcoholism
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, USA
    ScientificWorldJournal 6:1405-11. 2006
    ..Future studies are necessary to determine which interventions may reduce suicidal behavior in alcoholism...
  47. ncbi request reprint The role of brain-derived neurotrophic factor in the pathophysiology of adolescent suicidal behavior
    Leo Sher
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10468, USA
    Int J Adolesc Med Health 23:181-5. 2011
    ..It is interesting to hypothesize that BDNF could be a biological marker of suicidal behavior in adolescents or in certain adolescent populations...
  48. ncbi request reprint Relation between rates of suicide in 15-24-year-olds and per capita consumption of alcohol beverages in European countries
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917, Box 42 New York, NY 10032, USA
    Int J Adolesc Med Health 17:291-4. 2005
    ..Further studies are necessary to clarify the relation between suicide rates in different age groups and consumption of alcohol beverages...
  49. ncbi request reprint The relationship between the frequency of alcohol use and suicide rates in young people
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 18:81-5. 2006
    ..We examined the relationship between the percentage of frequently drinking high school students and suicide rates among 15-24 year olds in 17 countries...
  50. ncbi request reprint The concept of post-traumatic mood disorder
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917 Box 42, New York, NY 10032, United States
    Med Hypotheses 65:205-10. 2005
    ....
  51. doi request reprint The role of endogenous opioids in the pathophysiology of self-injurious and suicidal behavior
    Leo Sher
    Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, New York, NY 10032, USA
    Arch Suicide Res 12:299-308. 2008
    ..Future studies of the role of opioids in the biological mechanisms of NSSI and SB are merited and may lead to the development of new treatment modalities...
  52. ncbi request reprint Relation between rates of geriatric suicide and consumption of alcohol beverages in European countries
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY, USA
    ScientificWorldJournal 6:383-7. 2006
    ....
  53. ncbi request reprint Daily hassles, cortisol, and the pathogenesis of depression
    Leo Sher
    Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917, PO Box 42, New York, NY 10032, USA
    Med Hypotheses 62:198-202. 2004
    ....
  54. ncbi request reprint Alcoholism and seasonal affective disorder
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Compr Psychiatry 45:51-6. 2004
    ..Both mental health and drug and alcohol professionals should be provided with education to assist with appropriate identification, management, and referral of patients presenting with comorbid alcoholism and SAD...
  55. ncbi request reprint Etiology, pathogenesis, and treatment of seasonal and non-seasonal mood disorders: possible role of circadian rhythm abnormalities related to developmental alcohol exposure
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917, P O Box 42, New York, NY 10032, USA
    Med Hypotheses 62:797-801. 2004
    ..Therefore, subtle circadian rhythm abnormalities related to developmental alcohol exposure may affect treatment response in patients with mood disorders...
  56. doi request reprint A model of suicidal behavior in war veterans with posttraumatic mood disorder
    Leo Sher
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    Med Hypotheses 73:215-9. 2009
    ..Every nation, every generation, faces traumas that cause suicide. The world needs to deal with this and it is one thing that the world can come together on...
  57. ncbi request reprint Alcohol and adolescent suicide
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, 1051 Riverside Drive, Suite 2917, Box 42, New York, NY 10032, USA
    Int J Adolesc Med Health 17:197-203. 2005
    ..Future studies of psychological and neurobiological mechanisms of suicidality in adolescents with alcohol and/or substance abuse are merited...
  58. pmc Secondary prevention of suicide
    Debora Ganz
    Department of Psychiatry, Columbia University, New York, New York, USA
    PLoS Med 7:e1000271. 2010
    b>Leo Sher and colleagues discuss recent research on interventions to prevent secondary suicide and discuss the additional research that is needed.
  59. ncbi request reprint The constitutionality of random drug and alcohol testing of students in secondary schools
    Irene Estrin
    Administration, New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Adolesc Med Health 18:21-5. 2006
    ..Drug and alcohol testing programs in secondary schools may still be challenged on its legality. Therefore, examining court sanctioned programs and their long-term efficacy statistics is recommended...
  60. ncbi request reprint Functional magnetic resonance imaging in studies of neurocognitive effects of alcohol use on adolescents and young adults
    Leo Sher
    Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Int J Adolesc Med Health 18:3-7. 2006
    ..fMRI may be uniquely powerful in the delineation of the underlying pathophysiology of alcohol use disorders in adolescents and young adults...