Andrew J Sharp

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi Whole genome methylation profiling by immunoprecipitation of methylated DNA
    Andrew J Sharp
    Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY, USA
    Methods Mol Biol 925:69-78. 2012
  2. ncbi Methylation profiling in individuals with uniparental disomy identifies novel differentially methylated regions on chromosome 15
    Andrew J Sharp
    Department of Genetic Medicine and Development, University of Geneva, Geneva 1211, Switzerland
    Genome Res 20:1271-8. 2010
  3. ncbi DNA methylation profiles of human active and inactive X chromosomes
    Andrew J Sharp
    Department of Genetic Medicine and Development, University of Geneva, 1211 Geneva 4, Switzerland
    Genome Res 21:1592-600. 2011
  4. ncbi Evaluation of PRDM9 variation as a risk factor for recurrent genomic disorders and chromosomal non-disjunction
    Christelle Borel
    Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY 10029, USA
    Hum Genet 131:1519-24. 2012
  5. ncbi Tandem repeat sequence variation as causative cis-eQTLs for protein-coding gene expression variation: the case of CSTB
    Christelle Borel
    Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
    Hum Mutat 33:1302-9. 2012
  6. ncbi Detection of genomic variation by selection of a 9 mb DNA region and high throughput sequencing
    Sergey I Nikolaev
    Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
    PLoS ONE 4:e6659. 2009
  7. ncbi Detection of parent-of-origin specific expression quantitative trait loci by cis-association analysis of gene expression in trios
    Paras Garg
    Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
    PLoS ONE 7:e41695. 2012
  8. ncbi Emerging themes and new challenges in defining the role of structural variation in human disease
    Andrew J Sharp
    Department of Genetic Medicine and Development, University of Geneva Medical School, University Medical Center CMU, Geneva, Switzerland
    Hum Mutat 30:135-44. 2009

Collaborators

Detail Information

Publications8

  1. ncbi Whole genome methylation profiling by immunoprecipitation of methylated DNA
    Andrew J Sharp
    Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY, USA
    Methods Mol Biol 925:69-78. 2012
    ....
  2. ncbi Methylation profiling in individuals with uniparental disomy identifies novel differentially methylated regions on chromosome 15
    Andrew J Sharp
    Department of Genetic Medicine and Development, University of Geneva, Geneva 1211, Switzerland
    Genome Res 20:1271-8. 2010
    ..Application of this methodology to other chromosomes for which UPD has been reported will allow the systematic identification of imprinted sites throughout the genome...
  3. ncbi DNA methylation profiles of human active and inactive X chromosomes
    Andrew J Sharp
    Department of Genetic Medicine and Development, University of Geneva, 1211 Geneva 4, Switzerland
    Genome Res 21:1592-600. 2011
    ..Our study provides a detailed analysis of the epigenetic profile of active and inactive X chromosomes...
  4. ncbi Evaluation of PRDM9 variation as a risk factor for recurrent genomic disorders and chromosomal non-disjunction
    Christelle Borel
    Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY 10029, USA
    Hum Genet 131:1519-24. 2012
    ....
  5. ncbi Tandem repeat sequence variation as causative cis-eQTLs for protein-coding gene expression variation: the case of CSTB
    Christelle Borel
    Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
    Hum Mutat 33:1302-9. 2012
    ..More broadly, we propose that polymorphic tandem repeats may represent the causative variation of a fraction of cis-eQTLs in the genome...
  6. ncbi Detection of genomic variation by selection of a 9 mb DNA region and high throughput sequencing
    Sergey I Nikolaev
    Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
    PLoS ONE 4:e6659. 2009
    ....
  7. ncbi Detection of parent-of-origin specific expression quantitative trait loci by cis-association analysis of gene expression in trios
    Paras Garg
    Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
    PLoS ONE 7:e41695. 2012
    ..Our method represents a novel approach that can identify imprinted regulatory elements that control gene expression, suggesting novel PofO effects in the human genome...
  8. ncbi Emerging themes and new challenges in defining the role of structural variation in human disease
    Andrew J Sharp
    Department of Genetic Medicine and Development, University of Geneva Medical School, University Medical Center CMU, Geneva, Switzerland
    Hum Mutat 30:135-44. 2009
    ....