Affiliation: Mount Sinai School of Medicine
Alexeeva V, D Souza S, Schaniel C. A human MIXL1 green fluorescent protein reporter embryonic stem cell line engineered using TALEN-based genome editing. Stem Cell Res. 2016;17:93-96 pubmed publisher
..The utility of the MIXL1-eGFP reporter hESC line lies in the prospective isolation, lineage tracing, and developmental and mechanistic studies of MIXL1+ cell populations. ..
Gingold J, Coakley E, Su J, Lee D, Lau Z, Zhou H, et al
. Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen. BMC Bioinformatics. 2015;16:225 pubmed publisher
..We find several outliers from a mouse ESC RNAi screen that we confirm to be pluripotency regulators. Many of these outliers would have been missed by other analysis methods. ..
Klein S, Dvornik J, Yarrabothula A, Schaniel C. A Marfan syndrome human induced pluripotent stem cell line with a heterozygous FBN1 c.4082G>A mutation, ISMMSi002-B, for disease modeling. Stem Cell Res. 2017;23:73-76 pubmed publisher
..Furthermore, it can serve as a platform for drug discovery. ..