Research Topics
Genomes and Genes | Sasan RoayaieSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
A system of classifying microvascular invasion to predict outcome after resection in patients with hepatocellular carcinomaSasan Roayaie
Mount Sinai Liver Cancer Program, Mount Sinai School of Medicine, New York, New York 10029, USA
Gastroenterology 137:850-5. 2009..We examined a large cohort of patients with HCC who were treated by resection to identify features of mVI that correlated with recurrence and survival...
Second hepatic resection for recurrent hepatocellular cancer: a Western experienceSasan Roayaie
Mount Sinai Liver Cancer Program, Mount Sinai School of Medicine, New York, NY, USA
J Hepatol 55:346-50. 2011..We analyzed the outcomes of patients undergoing a second hepatic resection for recurrent hepatocellular cancer at a single Western center...
Recurrent hepatitis C after retransplantation: factors affecting graft and patient outcomeMichal Carmiel-Haggai
Recanati/Miller Transplantation Institute, Mount Sinai Hospital, The Mount Sinai School of Medicine, PO Box 1504, New York, NY 10029-6574, USA
Liver Transpl 11:1567-73. 2005..Patients experiencing early graft failure due to accelerated forms of HCV should not be denied re-LT with the expectation that a similar disease course will occur after re-LT...- Adult living donor liver transplantation for patients with hepatocellular carcinoma: extending UNOS priority criteriaGabriel E Gondolesi
Recanati Miller Transplantation Institutes, The Mount Sinai Hospital, New York, NY 10029, USA
Ann Surg 239:142-9. 2004..LDLT allows timely transplantation in patients with early or with large HCC... - Liver functional reserve estimation: state of the art and relevance to local treatmentsFotini Manizate
Department of Surgery, Division of Surgical Oncology, Mount Sinai Medical Center, New York, NY 10029, USA
Oncology 78:131-4. 2010..Preoperative portal vein embolization is a strategy that can evoke 'regeneration' in anticipation of surgery, serving as a 'stress test' of the liver's regenerative capacity... - Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivoPippa Newell
Mount Sinai Liver Cancer Program, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA
J Hepatol 51:725-33. 2009..We investigated the molecular alterations of the Ras pathway in HCC and the antineoplastic effects of sorafenib in combination with rapamycin, an inhibitor of mTOR pathway, in experimental models... - MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517aSara Toffanin
Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, New York, New York, USA
Gastroenterology 140:1618-28.e16. 2011..MicroRNAs (miRNAs) are involved in HCC pathogenesis, and their expression profiles have been used to classify cancers. We analyzed miRNA expression in human HCC samples to identify molecular subclasses and oncogenic miRNAs... - Combined adult-to-adult living donor right lobe liver transplantation and pancreatoduodenectomy for distal bile duct adenocarcinoma in a patient with primary sclerosing cholangitisGiovanni Varotti
Recanati/Miller Transplantation Institute, The Mount Sinai Hospital, New York, NY, USA
J Am Coll Surg 197:765-9. 2003..CONCLUSIONS: Combined living-donor liver transplantation and pancreatoduodenectomy is feasible and allows timely and elective surgical control of carefully selected distal bile duct tumors in the setting of end-stage liver disease... - Diaphragmatic hernia after hepatic resection: case series at a single Western institutionParissa Tabrizian
Mount Sinai Medical Center, New York, NY, USA
J Gastrointest Surg 16:1910-4. 2012..Diaphragmatic hernia (DH) after hepatic resection (HR) is a rare and not well-described complication. We report our experience with DH following a high volume of HRs in a tertiary center... - Hepatic resection for primary hepatolithiasis: a single-center Western experienceParissa Tabrizian
Mount Sinai Liver Cancer Program, Mount Sinai School of Medicine, New York, NY 10029, USA
J Am Coll Surg 215:622-6. 2012..We analyzed the outcomes of patients undergoing hepatic resection (HR) for PHL at a single Western center... - Gene-expression signature of vascular invasion in hepatocellular carcinomaBeatriz Minguez
Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Surgical Oncology, Department of Surgery, Department of Pathology, Department of Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
J Hepatol 55:1325-31. 2011..While macroscopic vascular invasion can be detected by radiological techniques, pre-operative detection of microscopic vascular invasion, which complicates 30-40% of patients with early tumors, remains elusive... - Recurrence of hepatocellular carcinoma after liver transplant: patterns and prognosisSasan Roayaie
Recanati Miller Transplantation Institute, Department of Medicine, Mount Sinai Medical Center, Mount Sinai NYU Health System, New York, NY 10029, USA
Liver Transpl 10:534-40. 2004..Nonetheless, some patients with recurrence can be expected to live for a considerable period of time. Recurrent disease should be treated surgically when possible, because surgery is independently associated with longer survival... - Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinomaElisa Wurmbach
Mount Sinai Liver Cancer Program, Division of Hematology Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
Hepatology 45:938-47. 2007..CONCLUSION: These findings provide a comprehensive molecular portrait of genomic changes in progressive HCV-related HCC... - Liver transplantation for hepatocellular carcinoma: extension of indications based on molecular markersMyron Schwartz
Mount Sinai Liver Cancer Program, Department of Surgery, Recanati Miller Transplantation Institute, Division of Liver Disease, New York, NY 10029, USA
J Hepatol 49:581-8. 2008..This study uses molecular data to identify a subgroup of patients who, despite having hepatocellular carcinoma beyond Milan criteria, have favorable outcomes... - Does anatomic versus nonanatomic resection affect recurrence and survival in patients undergoing surgery for colorectal liver metastasis?Umut Sarpel
Department of Surgery, New York University Medical Center, New York, USA
Ann Surg Oncol 16:379-84. 2009..An emphasis on the preservation of hepatic parenchyma may be of increasing importance in the setting of chemotherapy-associated steatohepatitis, and the growing number of patients undergoing repeated metastasectomy... - Strategies for the management of hepatocellular carcinomaMyron Schwartz
Mount Sinai School of Medicine, New York, NY 10029, USA
Nat Clin Pract Oncol 4:424-32. 2007..There is a need for more effective adjuvant therapies after resection and liver transplantation; newer antiangiogenic agents offer hope for improved outcomes in the future... - De novo hepatocellular carcinoma occurring in a transplanted liver: case report and review of the literatureAnca Croitoru
The Lillian and Henry M Stratton-Hans Popper Department of Pathology, The Mount Sinai Medical Center, One Gustave L Levy Place, New York, New York 10029, USA
Dig Dis Sci 51:1780-2. 2006 - Marked Differences in acute cellular rejection rates between living-donor and deceased-donor liver transplant recipientsLawrence U Liu
Recanati/Miller Transplantation Institute, The Mount Sinai Medical Center, New York, NY 10029, USA
Transplantation 80:1072-80. 2005..CONCLUSIONS.: Rates of ACR and high-degree ACR are decreased in living-related liver transplant recipients. This difference is likely genetically related as ACR rates are lower in recipient-donor pairs of increasing genetic similarity... - Liver transplantation for neuroendocrine tumorsSander Florman
Recanati Miller Transplantation Institute, The Mount Sinai School of Medicine, New York, New York, USA
J Gastrointest Surg 8:208-12. 2004..Of the three patients surviving more than 5 years, only one was disease free. In carefully selected patients with metastatic NETs, liver transplantation may be an appropriate option... - Feasibility and preliminary accuracy of high-resolution imaging of the liver and pancreas using FNA compatible microendoscopy (with video)Renu Regunathan
Department of Medicine, Columbia University, New York, New York, USA
Gastrointest Endosc 76:293-300. 2012..EUS-guided FNA is one of the few techniques that can obtain cells and tissue from the liver and pancreas. However, the technique remains vulnerable to poor specimen quality and sampling error... - Surgical resection for advanced gallbladder carcinoma. The Mount Sinai experienceManousos M Konstadoulakis
Recanati Miller Transplantation Institute, Mount Sinai School of Medicine, New York, NY, USA
Hepatogastroenterology 57:1005-12. 2010..Advanced gallbladder cancer (GC) carries dismal prognosis, due to its extent at diagnosis and the low R0 resection performance rate... - Fifteen-year, single-center experience with the surgical management of intrahepatic cholangiocarcinoma: operative results and long-term outcomeManousos M Konstadoulakis
Recanati Miller Transplantation Institute, Mount Sinai Medical Center, New York, NY, USA
Surgery 143:366-74. 2008..In the current report, we present our experience with the surgical management of ICC, analyze operative results, and investigate prognostic factors in resected patients... - FDG PET/CT imaging to rule out extrahepatic metastases before liver transplantationBharat Mocherla
Division of Nuclear Medicine, Department of Radiology, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
Clin Nucl Med 32:947-8. 2007..FDG PET/CT imaging revealed multiple FDG-avid pulmonary nodules that were subsequently confirmed to represent Mycobacterium avium intracellular infection on histology... - A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosisJosep M Llovet
Mount Sinai Liver Cancer Program, Department of Medicine, Mount Sinai School of Medicine, New York 10029, USA
Gastroenterology 131:1758-67. 2006..Small liver nodules approximately 2 cm are difficult to characterize by radiologic or pathologic examination. Our aim was to identify a molecular signature to diagnose early hepatocellular carcinoma (HCC)... - Neoadjuvant therapies for hepatocellular carcinoma before liver transplantation: a critical appraisalPatricia M Lopez
Mount Sinai Liver Cancer Program, Division of Liver Diseases, Mount Sinai School of Medicine, 1425 Madison Avenue, 11F-70, Box 1123, New York, NY 10029, USA
Liver Transpl 12:1747-54. 2006 - Liver transplantation for hepatocellular carcinoma: is expansion of criteria justified?Sasan Roayaie
Division of Liver Diseases and Recanati Miller Transplantation Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
Clin Liver Dis 9:315-28. 2005..It is estimated that by the year 2010, the number of patients with HCC awaiting liver transplant in the United States will outnumber the supply of cadaver organs... - Results of retransplantation for recurrent hepatitis CSasan Roayaie
Recanati Miller Transplantation Institute, Mount Sinai Hospital of Mount Sinai NYU Health, New York, NY 10029, USA
Hepatology 38:1428-36. 2003..Candidates for retransplantation with a preoperative PT less than 16 seconds and those receiving grafts from donors younger than 60 years can expect a significantly longer median survival after retransplantation... - Resection of hepatocellular carcinoma without cirrhosisBrian Shrager
Mount Sinai Liver Cancer Program, Mount Sinai Medical Center, New York, NY 10029, USA
Ann Surg 255:1135-43. 2012..The aim of this study was to examine the features and outcomes of noncirrhotic patients undergoing resection for hepatocellular carcinoma... - Liver functional reserve estimation: state of the art and relevance for local treatments: the Western perspectiveFotini Manizate
Department of Surgery, Division of Surgical Oncology, The Mount Sinai Medical Center, 5 East 98th Street, 12th Floor, Box 1259, New York, NY 10029, USA
J Hepatobiliary Pancreat Sci 17:385-8. 2010..Preoperative portal vein embolization is a strategy that can evoke regeneration in anticipation of surgery, serving as a "stress test" of the liver's regenerative capacity... - How should patients with hepatocellular carcinoma recurrence after liver transplantation be treated?Myron Schwartz
Recanati Miller Transplantation Institute, Mount Sinai School of Medicine, New York, USA
J Hepatol 43:584-9. 2005 - Post-liver transplant acute renal failure: factors predicting development of end-stage renal diseaseAnil S Paramesh
The Recanat/Miller Transplantation Institute, The Mount Sinai School of Medicine, New York, NY 10029-6574, USA
Clin Transplant 18:94-9. 2004..ESRD patients who received kidney transplantation had higher 10-yr survival rates when compared with patients maintained on dialysis... - Pivotal role of mTOR signaling in hepatocellular carcinomaAugusto Villanueva
Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
Gastroenterology 135:1972-83, 1983.e1-11. 2008..We evaluated mTOR signaling in human HCC, as well as the antitumoral effect of a dual-level blockade of the mTOR pathway... - Multifocal hepatocellular carcinoma and precancerous lesions in a patient with autoimmune hepatitis-related cirrhosisStephen C Ward
The Lillian and Henry M Stratton Hans Popper Department of Pathology, The Mount Sinai Medical Center, New York, New York 10029, USA
Semin Liver Dis 28:123-7. 2008..We believe this to be the first case in the English literature documenting the presence of preneoplastic lesions in an HCV-negative patient with AIH who developed HCC... - Recurrent pancreatic carcinoma and cholangiocarcinoma: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT)Katherine Cameron
Department of Radiology, Mount Sinai Medical Center, New York, NY 10029, USA
Abdom Imaging 36:463-71. 2011..This article reviews the nature of these carcinomas in the post-therapy setting and describes the strengths and limitations of PET/CT when used for monitoring recurrence... - Resection or transplant-listing for solitary hepatitis C-associated hepatocellular carcinoma: an intention-to-treat analysisHiroshi Sogawa
Recanati Miller Transplantation Institute, Mount Sinai Medical Center, New York, NY 10029, USA
HPB (Oxford) 15:134-41. 2013..This study was conducted to provide a retrospective intention-to-treat comparison of these two curative therapies... - A 48-year-old obese man with a 3 cm liver lesion and a history of hemochromatosis and lymphomaGabriel Levi
The Lillian and Henry M. Stratton-Hans Popper Department of Pathology, New York, NY 10029, USA
Semin Liver Dis 24:327-32. 2004 - The role of fibrin sealants in hepatic surgeryUmut Sarpel
Department of Surgery, Mount Sinai Medical Center, New York, NY, USA
Surg Technol Int 16:31-6. 2007..This chapter will discuss the basic science foundation of fibrin sealants and their applications in hepatic surgery... - Aggressive surgical resection for hilar cholangiocarcinoma: is it justified? Audit of a single center's experienceManousos M Konstadoulakis
Recanati Miller Transplantation Institute, Hippocration Hospital of Athens, Athens Medical School, Athens, Greece
Am J Surg 196:160-9. 2008..The current study presents our experience with resectional surgery for patients with hilar cholangiocarcinoma (HC)... - Carcinoma ex microcystic adenoma of the pancreas: a report of a novel form of malignancy in serous neoplasmsHongfa Zhu
Department of Pathology, The Mount Sinai Medical Center, New York, NY 10029, USA
Am J Surg Pathol 36:305-10. 2012..We believe that this case represents the first case of a cytologically malignant neoplasm arising from a benign serous cystadenoma (carcinoma ex microcystic serous cystadenoma)... - Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimetersSasan Roayaie
Recanati-Miller Transplantation Institute, New York, New York, USA
Ann Surg 235:533-9. 2002..Patients with tumors measuring 5 to 7 cm have significantly longer recurrence-free survival compared with those with larger tumors... - Hilar cholangiocarcinoma involving the portal vein bifurcation: long-term results after resectionLuis Munoz
The Mount Sinai School of Medicine, Recanati Miller Transplantation Institute, New York, NY, USA
J Hepatobiliary Pancreat Surg 9:237-41. 2002..Portal bifurcation involvement is often thought to contraindicate resection. We reviewed our experience with aggressive surgical management in 28 patients with hilar cholangiocarcinoma... - Giant hemangioma of the adrenalDaniel Silverberg
Recanati/Miller Transplantation Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
Isr Med Assoc J 6:705-6. 2004 - Resection of nonalcoholic steatohepatitis-associated hepatocellular carcinoma: a Western experienceBrian Shrager
Division of Surgical Oncology, Department of Surgery, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1259, New York, NY 10029, USA
Int J Surg Oncol 2012:915128. 2012..Conclusion. Hepatocellular carcinoma may arise in the context of nonalcoholic steatohepatitis, often before cirrhosis has developed. Locally advanced tumors are typical, and long-term failure rate following resection is high... - Renal artery thrombosis following secondary cytoreduction in a patient with ovarian cancerKonstantin Zakashansky
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai Medical Center, 1176 Fifth Avenue, Box 1173, New York, NY 10029 6574, USA
Gynecol Oncol 105:536-8. 2007..In order to successfully perform aggressive cytoreductive surgery for patients with recurrent epithelial ovarian cancer, resection of retroperitoneal disease in close proximity to major vessels is often required...