Vivek Y Reddy


Affiliation: Mount Sinai School of Medicine
Country: USA


  1. Reddy V, Koruth J, Jais P, Petru J, Timko F, Skalsky I, et al. Ablation of Atrial Fibrillation With Pulsed Electric Fields: An Ultra-Rapid, Tissue-Selective Modality for Cardiac Ablation. JACC Clin Electrophysiol. 2018;4:987-995 pubmed publisher
    ..The catheter time for epicardial ablation was 50.7 ± 19.5 min. There were no complications. These data usher in a new era of tissue-specific, ultrarapid ablation of atrial fibrillation. ..
  2. Bhardwaj R, Naniwadekar A, Whang W, Mittnacht A, Palaniswamy C, Koruth J, et al. Esophageal Deviation During Atrial Fibrillation Ablation: Clinical Experience With a Dedicated Esophageal Balloon Retractor. JACC Clin Electrophysiol. 2018;4:1020-1030 pubmed publisher
    ..MED with the balloon retractor safely moved the esophagus away from the site of energy delivery during atrial fibrillation ablation. ..
  3. Dukkipati S, Cuoco F, Kutinsky I, Aryana A, Bahnson T, Lakkireddy D, et al. Pulmonary Vein Isolation Using the Visually Guided Laser Balloon: A Prospective, Multicenter, and Randomized Comparison to Standard Radiofrequency Ablation. J Am Coll Cardiol. 2015;66:1350-60 pubmed publisher
    ..Pivotal Clinical Study of the CardioFocus Endoscopic Ablation System-Adaptive Contact [EAS-AC] [HeartLight] in Patients With Paroxysmal Atrial Fibrillation [PAF] [HeartLight]; NCT01456000). ..
  4. Koruth J, Schneider C, Avitall B, Ribeiro L, Dukkipati S, Walcott G, et al. Pre-Clinical Investigation of a Low-Intensity Collimated Ultrasound System for Pulmonary Vein Isolation in a Porcine Model. JACC Clin Electrophysiol. 2015;1:306-314 pubmed publisher
    ..This study demonstrates the safety and efficacy of a novel noncontact ultrasound mapping and ablation system to produce continuous transmural lesions that can isolate PVs in a porcine model. ..
  5. Reddy V, Pollak S, Lindsay B, McElderry H, Natale A, Kantipudi C, et al. Relationship Between Catheter Stability and 12-Month Success After Pulmonary Vein Isolation: A Subanalysis of the SMART-AF Trial. JACC Clin Electrophysiol. 2016;2:691-699 pubmed publisher
    ..In the SMART-AF trial, CF stability with sufficient CF was most predictive of optimal 12-month success. (Thermocool Smarttouch Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation [SMART-AF]; NCT01385202). ..
  6. Reddy V, Doshi S, Sievert H, Buchbinder M, Neuzil P, Huber K, et al. Percutaneous left atrial appendage closure for stroke prophylaxis in patients with atrial fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with Atrial Fibrillation) Trial. Circulation. 2013;127:720-9 pubmed publisher
    ..PROTECT AF has, for the first time, implicated the left atrial appendage in the pathogenesis of stroke in atrial fibrillation. : URL: Unique identifier: NCT00129545. ..
  7. Reddy V, Dukkipati S, Neuzil P, Natale A, Albenque J, Kautzner J, et al. Randomized, Controlled Trial of the Safety and Effectiveness of a Contact Force-Sensing Irrigated Catheter for Ablation of Paroxysmal Atrial Fibrillation: Results of the TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation (TOCCAST. Circulation. 2015;132:907-15 pubmed publisher
    ..0004 for noninferiority). The CF ablation catheter met the primary safety and effectiveness end points. Additionally, optimal CF was associated with improved effectiveness. Unique identifier: NCT01278953. ..
  8. Koruth J, Rippy M, Khairkhahan A, Ligon D, Hubbard C, Miller M, et al. Percutaneous Retrieval of Implanted Leadless Pacemakers: Feasibility at 2.5 Years Post-Implantation in an In Vivo Ovine Model. JACC Clin Electrophysiol. 2015;1:563-570 pubmed publisher
    ..There was no evidence of pulmonary thromboembolism. We demonstrate the feasibility and safety of percutaneous, catheter-based retrieval in chronic LP implants of a maximum duration of approximately 2.5 years. ..
  9. Palaniswamy C, Koruth J, Mittnacht A, Miller M, Choudry S, Bhardwaj R, et al. The Extent of Mechanical Esophageal Deviation to Avoid Esophageal Heating During Catheter Ablation of Atrial Fibrillation. JACC Clin Electrophysiol. 2017;3:1146-1154 pubmed publisher

More Information


  1. Reddy V, Akehurst R, Amorosi S, Gavaghan M, Hertz D, Holmes D. Cost-Effectiveness of Left Atrial Appendage Closure With the WATCHMAN Device Compared With Warfarin or Non-Vitamin K Antagonist Oral Anticoagulants for Secondary Prevention in Nonvalvular Atrial Fibrillation. Stroke. 2018;49:1464-1470 pubmed publisher
  2. Dukkipati S, Kar S, Holmes D, Doshi S, Swarup V, Gibson D, et al. Device-Related Thrombus After Left Atrial Appendage Closure: Incidence, Predictors, and Outcomes. Circulation. 2018;: pubmed publisher
    ..62%) occurred in patients without DRT. Conclusions -After LAAC with Watchman, DRT (~3.7%) is not frequent, but when present, is associated with a higher rate of stroke and systemic embolism. ..
  3. Miller M, Neuzil P, Dukkipati S, Reddy V. Leadless Cardiac Pacemakers: Back to the Future. J Am Coll Cardiol. 2015;66:1179-89 pubmed publisher
    ..This review summarizes the current evidence and potential benefits of leadless pacing systems, which are either commercially available (in Europe) or under clinical investigation. ..
  4. Reddy V, Gibson D, Kar S, O NEILL W, Doshi S, Horton R, et al. Post-Approval U.S. Experience With Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation. J Am Coll Cardiol. 2017;69:253-261 pubmed publisher
    ..078%). Despite a large fraction of previously inexperienced operators, in the real-world post-FDA approval experience of LAAC, procedural success was high and complication rates were low. ..
  5. request reprint
    Reddy V, Miller M, Knops R, Neuzil P, Defaye P, Jung W, et al. Retrieval of the Leadless Cardiac Pacemaker: A Multicenter Experience. Circ Arrhythm Electrophysiol. 2016;9: pubmed
    ..URL: Unique identifiers: NCT02051972, NCT02030418, and NCT01700244. ..
  6. Enomoto Y, Gadiyaram V, Gianni C, Horton R, Trivedi C, Mohanty S, et al. Use of non-warfarin oral anticoagulants instead of warfarin during left atrial appendage closure with the Watchman device. Heart Rhythm. 2017;14:19-24 pubmed publisher
  7. Singh S, d Avila A, Kim Y, Aryana A, Mangrum J, Michaud G, et al. The modified stepwise ablation guided by low-dose ibutilide in chronic atrial fibrillation trial (The MAGIC-AF Study). Eur Heart J. 2016;37:1614-21 pubmed publisher number: NCT01014741. ..
  8. Reddy V, Akehurst R, Armstrong S, Amorosi S, Brereton N, Hertz D, et al. Cost effectiveness of left atrial appendage closure with the Watchman device for atrial fibrillation patients with absolute contraindications to warfarin. Europace. 2016;18:979-86 pubmed publisher
    ..This analysis demonstrates that LAAC with the Watchman device is a cost-effective and cost-saving solution for stroke risk reduction in patients with non-valvular AF who are at risk for stroke but have contraindications to warfarin. ..
  9. Reddy V, Akehurst R, Armstrong S, Amorosi S, Beard S, Holmes D. Time to Cost-Effectiveness Following Stroke Reduction Strategies in AF: Warfarin Versus NOACs Versus LAA Closure. J Am Coll Cardiol. 2015;66:2728-2739 pubmed publisher
    ..The results of this analysis should be considered when formulating policy and practice guidelines for stroke prevention in AF. ..
  10. Tjong F, Reddy V. Permanent Leadless Cardiac Pacemaker Therapy: A Comprehensive Review. Circulation. 2017;135:1458-1470 pubmed publisher
    ..Although current leadless pacemakers are limited to right ventricular pacing, future advanced, communicating, multicomponent systems are expected to expand the potential benefits of leadless therapy to a larger patient population. ..
  11. Reddy V, Holmes D, Doshi S, Neuzil P, Kar S. Safety of percutaneous left atrial appendage closure: results from the Watchman Left Atrial Appendage System for Embolic Protection in Patients with AF (PROTECT AF) clinical trial and the Continued Access Registry. Circulation. 2011;123:417-24 pubmed publisher
    ..Clinical Trial Registration- URL: Unique identifier: NCT00129545. ..
  12. Reddy V, Shah D, Kautzner J, Schmidt B, Saoudi N, Herrera C, et al. The relationship between contact force and clinical outcome during radiofrequency catheter ablation of atrial fibrillation in the TOCCATA study. Heart Rhythm. 2012;9:1789-95 pubmed publisher
    ..Arrhythmia control is best achieved when ablation lesions are placed with an average CF of >20 g, and clinical failure is universally noted with an average CF of <10 g. ..
  13. Dukkipati S, Koruth J, Choudry S, Miller M, Whang W, Reddy V. Catheter Ablation of Ventricular Tachycardia in Structural Heart Disease: Indications, Strategies, and Outcomes-Part II. J Am Coll Cardiol. 2017;70:2924-2941 pubmed publisher
    ..The goal of this paper is to review the pathophysiology, mechanism, and management of VT in the setting of structural heart disease and discuss the evolving role of catheter ablation in decreasing ventricular arrhythmia recurrence. ..
  14. Dukkipati S, Choudry S, Koruth J, Miller M, Whang W, Reddy V. Catheter Ablation of Ventricular Tachycardia in Structurally Normal Hearts: Indications, Strategies, and Outcomes-Part I. J Am Coll Cardiol. 2017;70:2909-2923 pubmed publisher
    ..Here, the authors discuss the pathophysiology, mechanism, and management of VT that occurs in the setting of a structurally normal heart and the role of catheter ablation. ..
  15. Reddy V, Doshi S, Kar S, Gibson D, Price M, Huber K, et al. 5-Year Outcomes After Left Atrial Appendage Closure: From the PREVAIL and PROTECT AF Trials. J Am Coll Cardiol. 2017;70:2964-2975 pubmed publisher
  16. Iwasawa J, Koruth J, Petru J, Dujka L, Kralovec S, Mzourkova K, et al. Temperature-Controlled Radiofrequency Ablation for Pulmonary Vein Isolation in Patients With Atrial Fibrillation. J Am Coll Cardiol. 2017;70:542-553 pubmed publisher
    ..ACT DiamondTemp Temperature-Controlled and Contact Sensing RF Ablation Clinical Trial for Atrial Fibrillation [TRAC-AF]; NCT02821351). ..
  17. Reddy V, Miller M, Neuzil P, Søgaard P, Butter C, Seifert M, et al. Cardiac Resynchronization Therapy With Wireless Left Ventricular Endocardial Pacing: The SELECT-LV Study. J Am Coll Cardiol. 2017;69:2119-2129 pubmed publisher
    ..Safety and Performance of Electrodes Implanted in the Left Ventricle [SELECT-LV]; NCT01905670). ..
  18. Reddy V, Mobius Winkler S, Miller M, Neuzil P, Schuler G, Wiebe J, et al. Left atrial appendage closure with the Watchman device in patients with a contraindication for oral anticoagulation: the ASAP study (ASA Plavix Feasibility Study With Watchman Left Atrial Appendage Closure Technology). J Am Coll Cardiol. 2013;61:2551-6 pubmed publisher
    ..ASA Plavix Feasibility Study With Watchman Left Atrial Appendage Closure Technology [ASAP]; NCT00851578). ..