Jason J Radley

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi request reprint 5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus
    Jason J Radley
    Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Brain Res 955:264-7. 2002
  2. ncbi request reprint Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism
    Jason J Radley
    Program in Neuroscience, Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Brain Res 966:1-12. 2003
  3. ncbi request reprint Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex
    J J Radley
    Kastor Neurobiology of Aging Laboratories and Fishberg Research Center for Neurobiology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroscience 125:1-6. 2004
  4. ncbi request reprint Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Exp Neurol 196:199-203. 2005
  5. ncbi request reprint Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
    Conor Liston
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10021, USA
    J Neurosci 26:7870-4. 2006
  6. pmc Distribution of NMDA and AMPA receptor subunits at thalamo-amygdaloid dendritic spines
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Brain Res 1134:87-94. 2007
  7. pmc Stress risk factors and stress-related pathology: neuroplasticity, epigenetics and endophenotypes
    Jason J Radley
    Department of Psychology, University of Iowa, Iowa City, IA, USA
    Stress 14:481-97. 2011
  8. ncbi request reprint Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cereb Cortex 16:313-20. 2006
  9. pmc A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response
    Jason J Radley
    Department of Psychology, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 31:9683-95. 2011
  10. pmc Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex
    Jason J Radley
    Laboratory of Neuronal Structure and Function, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Comp Neurol 507:1141-50. 2008

Detail Information

Publications14

  1. ncbi request reprint 5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus
    Jason J Radley
    Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Brain Res 955:264-7. 2002
    ..This suggests that 5-HT(1A) receptor activity is important during naturally occurring cell proliferation in the dentate gyrus, and perhaps neurogenesis, and is one of the many factors involved in its regulation...
  2. ncbi request reprint Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism
    Jason J Radley
    Program in Neuroscience, Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Brain Res 966:1-12. 2003
    ....
  3. ncbi request reprint Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex
    J J Radley
    Kastor Neurobiology of Aging Laboratories and Fishberg Research Center for Neurobiology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroscience 125:1-6. 2004
    ....
  4. ncbi request reprint Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Exp Neurol 196:199-203. 2005
    ..These results suggest that stress-induced dendritic plasticity in the medial PFC is reversible and may have implications for the functional recovery of medial PFC function following prolonged psychological stress...
  5. ncbi request reprint Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
    Conor Liston
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10021, USA
    J Neurosci 26:7870-4. 2006
    ..This study provides the first direct evidence that dendritic remodeling in the prefrontal cortex may underlie the functional deficits in attentional control that are symptomatic of stress-related mental illnesses...
  6. pmc Distribution of NMDA and AMPA receptor subunits at thalamo-amygdaloid dendritic spines
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Brain Res 1134:87-94. 2007
    ....
  7. pmc Stress risk factors and stress-related pathology: neuroplasticity, epigenetics and endophenotypes
    Jason J Radley
    Department of Psychology, University of Iowa, Iowa City, IA, USA
    Stress 14:481-97. 2011
    ..Together, the symposium highlighted emerging themes regarding the role of brain reorganization, individual differences, and epigenetics in determining stress plasticity and pathology...
  8. ncbi request reprint Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cereb Cortex 16:313-20. 2006
    ..Dendritic atrophy and spine loss may be important cellular features of stress-related psychiatric disorders where the PFC is functionally impaired...
  9. pmc A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response
    Jason J Radley
    Department of Psychology, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 31:9683-95. 2011
    ..These findings support the view that stress-inhibitory influences of mPFC and HF are exerted principally via convergence onto a common relay, as opposed to a serial, parallel, or more complex multisynaptic network...
  10. pmc Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex
    Jason J Radley
    Laboratory of Neuronal Structure and Function, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Comp Neurol 507:1141-50. 2008
    ..These results suggest a failure of spines to mature and stabilize following repeated stress and are likely to have major repercussions on function, receptor expression, and synaptic efficacy...
  11. ncbi request reprint Repeated stress and structural plasticity in the brain
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Ageing Res Rev 4:271-87. 2005
    ..How functional impairments in these brain regions play a role in stress-related mental illnesses is discussed in this context. Finally, we discuss the cumulative impact of stress-induced structural plasticity in aging...
  12. ncbi request reprint Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, and Foundation for Medical Research, La Jolla, California 92037, USA
    J Neurosci 26:12967-76. 2006
    ..These results suggest that dorsal and ventral aspects of the mPFC differentially regulate neuroendocrine and autonomic PVH outputs in response to emotional stress...
  13. pmc Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, Clayton Medical Research Foundation, La Jolla, California 92037, USA
    J Neurosci 28:5806-16. 2008
    ..These findings identify the LC as an upstream component of a circuitry providing for dorsal mPFC modulation of emotional stress-induced HPA activation...
  14. ncbi request reprint Associative Pavlovian conditioning leads to an increase in spinophilin-immunoreactive dendritic spines in the lateral amygdala
    Jason J Radley
    Laboratory for Neuronal Structure and Function, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Eur J Neurosci 24:876-84. 2006
    ....