Eib Peerschke

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage
    Victor Friedrich
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Neuroinflammation 8:103. 2011
  2. ncbi Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid antibodies
    E I B Peerschke
    Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10029, USA
    Lupus 18:530-8. 2009
  3. ncbi Complement activation on platelets correlates with a decrease in circulating immature platelets in patients with immune thrombocytopenic purpura
    Ellinor I B Peerschke
    Weill Cornell Medical College of Cornell University, New York, NY, USA
    Br J Haematol 148:638-45. 2010
  4. ncbi Complement activation on platelets: implications for vascular inflammation and thrombosis
    Ellinor I Peerschke
    Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mol Immunol 47:2170-5. 2010
  5. ncbi Blood platelets activate the classical pathway of human complement
    E I B Peerschke
    Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY, USA
    J Thromb Haemost 4:2035-42. 2006

Research Grants

  1. gClqR/p33 in S. Aureus Endovascular Pathogenesis
    Ellinor Peerschke; Fiscal Year: 2005

Collaborators

Detail Information

Publications5

  1. ncbi Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage
    Victor Friedrich
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Neuroinflammation 8:103. 2011
    ..SAH was induced by endovascular perforation. Neutrophil infiltration and the integrity of vascular endothelium and basement membrane were assessed immunohistochemically. Vascular collagenase activity was assessed by in situ zymography...
  2. ncbi Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid antibodies
    E I B Peerschke
    Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10029, USA
    Lupus 18:530-8. 2009
    ..039). Sera from patients with aPL possess an enhanced capacity for in-situ complement fixation on platelets. This capacity may influence arterial thrombosis risk in patients with SLE...
  3. ncbi Complement activation on platelets correlates with a decrease in circulating immature platelets in patients with immune thrombocytopenic purpura
    Ellinor I B Peerschke
    Weill Cornell Medical College of Cornell University, New York, NY, USA
    Br J Haematol 148:638-45. 2010
    ..063). Thus, complement fixation may contribute to the thrombocytopenia of ITP by enhancing clearance of opsonized platelets from the circulation, and/or directly damaging platelets and megakaryocytes...
  4. ncbi Complement activation on platelets: implications for vascular inflammation and thrombosis
    Ellinor I Peerschke
    Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mol Immunol 47:2170-5. 2010
    ..Taken together, these data support a role for platelet mediated complement activation in vascular inflammation and thrombosis...
  5. ncbi Blood platelets activate the classical pathway of human complement
    E I B Peerschke
    Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY, USA
    J Thromb Haemost 4:2035-42. 2006
    ..As platelets also posses binding sites for C1q, the recognition unit of the classical complement pathway, the present study examined classical pathway activation on platelets...

Research Grants4

  1. gClqR/p33 in S. Aureus Endovascular Pathogenesis
    Ellinor Peerschke; Fiscal Year: 2005
    ..Results from these studies will define a novel mechanism for S. aureus interactions at sites of endovascular damage, and may identify novel targets for therapeutic intervention. ..