Research Topics
Species | Anna Nowak-WegrzynSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Food protein-induced enterocolitis syndrome caused by solid food proteinsAnna Nowak-Wegrzyn
Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
Pediatrics 111:829-35. 2003..Infantile food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated gastrointestinal food hypersensitivity typically provoked by cow's milk or soy. Solid foods are rarely considered a cause...
Tolerance to extensively heated milk in children with cow's milk allergyAnna Nowak-Wegrzyn
Department of Pediatrics and Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 122:342-7, 347.e1-2. 2008....
Mediator release assay for assessment of biological potency of German cockroach allergen extractsAnna H Nowak-Wegrzyn
Division of Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 123:949-955.e1. 2009..Cockroach is an important allergen in inner-city asthma. The diagnosis and treatment of cockroach allergy has been impeded by the lack of standardized cockroach extracts...- Rare, medium, or well done? The effect of heating and food matrix on food protein allergenicityAnna Nowak-Wegrzyn
Jaffe Food Allergy Institute and Department of Pediatrics, Mount Sinai School of Medicine, New York, New York, USA
Curr Opin Allergy Clin Immunol 9:234-7. 2009..To review recent advances in the area of food allergen processing and the effect on protein allergenicity... - New perspectives for use of native and engineered recombinant food proteins in treatment of food allergyAnna Nowak-Wegrzyn
Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, Box 1198, One G Levy Place, NY 10029, USA
Immunol Allergy Clin North Am 27:105-27. 2007..This article reviews the recent developments in the potential treatments for IgE-mediated food allergy using native and engineered recombinant food proteins... - Food allergy to proteinsAnna Nowak-Wegrzyn
Jaffe Food Allergy Institute, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
Nestle Nutr Workshop Ser Pediatr Program 59:17-31; discussion 31-6. 2007..Taken together, these data suggest that the epitope recognition pattern and intensity of IgE binding are important determinants of severity and duration of food allergy... - Food protein-induced enterocolitis syndromeAnna Nowak-Wegrzyn
Jaffe Food Allergy Institute, Department of Pediatrics, Mount Sinai School of Medicine, Division of Allergy and Immunology, 1 Gustave L Levy Place, Box 1198, New York, NY 10029, USA
Curr Opin Allergy Clin Immunol 9:371-7. 2009..To review current knowledge and recent advances in food protein-induced enterocolitis syndrome (FPIES)... - Is oral immunotherapy the cure for food allergies?Anna Nowak-Wegrzyn
Jaffe Food Allergy Institute and Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
Curr Opin Allergy Clin Immunol 10:214-9. 2010..To review current evidence on food oral immunotherapy (OIT)... - Immunotherapy for food allergyAnna Nowak-Wegrzyn
Mount Sinai School of Medicine, Department of Pediatrics, Division of Allergy and Immunology and Jaffe Food Allergy Institute, New York, NY 10029, USA
Inflamm Allergy Drug Targets 5:23-34. 2006.... - Future approaches to food allergyAnna Nowak-Wegrzyn
Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
Pediatrics 111:1672-80. 2003.... - Dietary baked egg accelerates resolution of egg allergy in childrenStephanie A Leonard
Division of Pediatric Allergy, Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 130:473-80.e1. 2012..Baked egg is tolerated by a majority of egg-allergic children... - Epinephrine treatment is infrequent and biphasic reactions are rare in food-induced reactions during oral food challenges in childrenKirsi M Järvinen
Division of Pediatric Allergy and Immunology and the Jaffe Institute for Food Allergy, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
J Allergy Clin Immunol 124:1267-72. 2009..Data about epinephrine use and biphasic reactions in childhood food-induced anaphylaxis during oral food challenges are scarce... - Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosaStephanie A Leonard
Division of Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 129:1579-1587.e1. 2012..Studies are needed to elucidate mechanisms of clinical protection and to identify safer and potentially more efficacious methods for desensitizing patients to food allergens... - Significance of ovomucoid- and ovalbumin-specific IgE/IgG(4) ratios in egg allergyJean Christoph Caubet
Department of Pediatrics, Division of Allergy and Immunology, Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10028, USA
J Allergy Clin Immunol 129:739-47. 2012.... - Food allergy therapyAnna Nowak-Wegrzyn
Division of Allergy and Immunology, Department of Pediatrics, Jaffe Food Allergy Institute, Mount Sinai School of Medicine, One G. Levy Place, Box 1198, New York, NY 10029, USA
Immunol Allergy Clin North Am 24:705-25, viii. 2004..Animal models of food allergy are invaluable in testing new therapies for food allergy... - Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergyJulie Wang
Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
J Allergy Clin Immunol 125:695-702, 702.e1-702.e6. 2010..Results from large-scale epitope mapping with a peptide microarray have been shown to correlate with clinical features of milk allergy... - Allergen-specific basophil suppression associated with clinical tolerance in patients with milk allergyNiya Wanich
Division of Allergy and Immunology, Department of Pediatrics, Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 123:789-94.e20. 2009..Children with milk allergy who tolerate heat-denatured milk (HM) have less severe reactions and outgrow the condition earlier than those who react to HM, which might be related to differences in IgE-dependent effector cell function... - Molecular diagnosis of egg allergyJean Christoph Caubet
Jaffe Food Allergy Institute, Department of Pediatrics, Division of Allergy and Immunology, Mount Sinai School of Medicine, New York 10029, USA
Curr Opin Allergy Clin Immunol 11:210-5. 2011..In this article, we will review the recent literature regarding the potential value of these tests for the clinical management of egg-allergic patients... - In vitro assessment of the allergenicity of novel MF59-adjuvanted pandemic H1N1 influenza vaccine produced in dog kidney cellsRamon Bencharitiwong
Mount Sinai School of Medicine, New York, NY, USA
Hum Vaccin Immunother 8:863-5. 2012.... - Food allergy therapy: is a cure within reach?Anna Nowak-Wegrzyn
Department of Pediatrics, Jaffe Food Allergy Institute, Mount Sinai School of Medicine, Box 1198, One Gustave L Levy Place, New York, NY 10029, USA
Pediatr Clin North Am 58:511-30, xii. 2011..Diet containing heated milk and egg may represent an alternative approach to oral immunomodulation. Oral food immunotherapy remains an investigational treatment to be further studied before advancing into clinical practice... - In vitro assessment of the allergenicity of a novel influenza vaccine produced in dog kidney cells in individuals with dog allergyNiya Wanich
Department of Pediatrics, Mount Sinai School of Medicine, New York, New York 10029, USA
Ann Allergy Asthma Immunol 104:426-33. 2010..Although no major dog allergens were identified in MDCK 33016-PF cells, minor dog allergens might be present and cause reactions in dog-allergic individuals... - Mechanisms underlying differential food allergy response to heated eggGustavo Martos
Department of Pediatrics and Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 127:990-7.e1-2. 2011..Egg white proteins are usually subjected to heating, making them edible for the majority of children with egg allergy... - Skin prick test to egg white provides additional diagnostic utility to serum egg white-specific IgE antibody concentration in childrenAdina Kay Knight
Department of Medicine, Division of Clinical Immunology, Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 117:842-7. 2006..CLINICAL IMPLICATIONS: The size of the egg white SPT wheal response might provide the clinician with additional information to determine the timing of egg OFC in children with low egg white-specific IgE antibody levels... - Allergic eosinophilic gastroenteritis with protein-losing enteropathy: intestinal pathology, clinical course, and long-term follow-upMirna Chehade
Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY 10029, USA
J Pediatr Gastroenterol Nutr 42:516-21. 2006..Our goals were to describe the response to therapy and the long-term outcome of patients in this subgroup and to evaluate their gastric and intestinal biopsies for distinguishing features that might explain their protein and blood loss... - Immunologic changes in children with egg allergy ingesting extensively heated eggHeather Lemon-Mule
Department of Pediatrics, Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 122:977-983.e1. 2008..Prior studies have suggested that heated egg might be tolerated by some children with egg allergy... - Extensively heated milk and egg as oral immunotherapyFaith Huang
Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai Medical School, New York, New York, USA
Curr Opin Allergy Clin Immunol 12:283-92. 2012..The introduction of extensively heated milk and egg protein into the diet has been explored in recent years... - Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk proteinWayne G Shreffler
Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, New York, NY 10029, USA
J Allergy Clin Immunol 123:43-52.e7. 2009..About 70% of children with milk allergy tolerate extensively heated milk (HM) products and outgrow their allergy earlier than those who react to HM... - Educational clinical case series for pediatric allergy and immunology: allergic proctocolitis, food protein-induced enterocolitis syndrome and allergic eosinophilic gastroenteritis with protein-losing gastroenteropathy as manifestations of non-IgE-mediateJennifer Maloney
Mount Sinai School of Medicine, Department of Pediatrics, Division of Allergy and Immunology and Jaffe Food Allergy Institute, New York, NY 10029, USA
Pediatr Allergy Immunol 18:360-7. 2007..Elemental diet based on the amino-acid formula leads to resolutions of gastrointestinal eosinophilic inflammation typically within 6 wk... - Sarcoplasmic calcium-binding protein is an EF-hand-type protein identified as a new shrimp allergenRosalia Ayuso
Division of Allergy and Immunology and the Jaffe Food Allergy Research Institute, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1198, New York, NY 10029, USA
J Allergy Clin Immunol 124:114-20. 2009..Shellfish allergy is a long-lasting disorder usually persisting throughout life. Despite its high prevalence, there is limited information about allergenic shrimp proteins... - Anaphylaxis in a New York City pediatric emergency department: triggers, treatments, and outcomesFaith Huang
Department of Pediatrics and Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY, USA
J Allergy Clin Immunol 129:162-8.e1-3. 2012..Anaphylaxis incidence is increasing... - Food protein-induced enterocolitis syndrome: an update on natural history and review of managementStephanie A Leonard
Jaffe Food Allergy Institute, Division of Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
Ann Allergy Asthma Immunol 107:95-101; quiz 101, 162. 2011..To review the clinical features, pathophysiology, and management of food protein-induced enterocolitis syndrome (FPIES) and to discuss new observations in epidemiology and natural history... - Dietary baked milk accelerates the resolution of cow's milk allergy in childrenJennifer S Kim
Department of Pediatrics and the Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 128:125-131.e2. 2011..The majority (approximately 75%) of children with cow's milk allergy tolerate extensively heated (baked) milk products. Long-term effects of inclusion of dietary baked milk have not been reported... - Work Group report: oral food challenge testingAnna Nowak-Wegrzyn
Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY, USA
J Allergy Clin Immunol 123:S365-83. 2009..A negative oral food challenge result allows introduction of the food into the diet, whereas a positive oral food challenge result provides a sound basis for continued avoidance of the food... - Future therapies for food allergiesAnna Nowak-Wegrzyn
Mount Sinai School of Medicine, Pediatric Allergy and Immunology, Jaffe Food Allergy Institute, New York, NY 10029, USA
J Allergy Clin Immunol 127:558-73; quiz 574-5. 2011..The variety of strategies for treating food allergy increases the likelihood of success and gives hope that accomplishing an effective therapy for food allergy is within reach... - A 17-month-old boy with periorbital swellingJimmy Ko
Division of Pediatric Allergy and Immunology and the Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, New York, USA
Ann Allergy Asthma Immunol 93:220-6. 2004 - Current understanding of the immune mechanisms of food protein-induced enterocolitis syndromeJean Christoph Caubet
Jaffe Food Allergy Institute, Department of Pediatrics, Division of Allergy and Immunology, Mount Sinai School of Medicine, New York, NY, USA
Expert Rev Clin Immunol 7:317-27. 2011..The aim of this article is to delineate the immunological characteristics of this disorder based on the existing reports and to review the possible pathophysiologic basis of this disease... - Transcytosis of IgE-antigen complexes by CD23a in human intestinal epithelial cells and its role in food allergyHongxing Li
Department of Medicine Division of Clinical Immunology, Mount Sinai School of Medicine, New York, New York 10029, USA
Gastroenterology 131:47-58. 2006..We examined whether IgE also could facilitate transepithelial antigen sampling... - Use of multiple doses of epinephrine in food-induced anaphylaxis in childrenKirsi M Järvinen
Division of Pediatric Allergy and Immunology and Jaffe Institute for Food Allergy, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
J Allergy Clin Immunol 122:133-8. 2008..Food allergy is the most common cause of anaphylaxis outside the hospital setting... - Vaccines and immunomodulatory therapies for food allergyJay A Lieberman
Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
Curr Allergy Asthma Rep 12:55-63. 2012..With these emerging therapeutic strategies, it is hoped that practitioners will have options in caring for their food-allergic patients in the near future... - A survey on the management of pollen-food allergy syndrome in allergy practicesSonghui Ma
Mount Sinai School of Medicine, Department of Pediatrics, Division of Allergy and Immunology, New York, NY 10029, USA
J Allergy Clin Immunol 112:784-8. 2003..Discrepancies might be related to the term OAS, and therefore use of the more specific term "pollen-food allergy syndrome" is suggested... - De novo food allergy after intestinal transplantation: a report of three casesMirna Chehade
Division of Pediatric Gastroenterology, Nutrition and Liver Diseases, Mount Sinai School of Medicine, New York, New York, USA
J Pediatr Gastroenterol Nutr 38:545-7. 2004 - Adverse reactions to foodsAnna Nowak-Wegrzyn
Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
Med Clin North Am 90:97-127. 2006..Anti-IgE monoclonal antibody is the first potential therapy for food allergy that is under-going testing in clinical trials... - Clinical diagnosis and management of food protein-induced enterocolitis syndromeStephanie A Leonard
aDepartment of Pediatrics, Division of Allergy and Immunology, University of California, San Diego, Rady Children s Hospital, San Diego, California bJaffe Food Allergy Institute, Division of Pediatric Allergy, Mount Sinai School of Medicine, New York, New York, USA
Curr Opin Pediatr 24:739-45. 2012..This review will highlight updates on natural history and clinical management... - Reactions of 2 young children with milk allergy after cutaneous exposure to milk-containing cosmetic productsJulie Wang
Mount Sinai Hospital, Department of Pediatrics, Box 1198, 1 Gustave L. Levy Pl, New York, NY 10029, USA
Arch Pediatr Adolesc Med 158:1089-90. 2004 - Contamination of dry powder inhalers for asthma with milk proteins containing lactoseAnna Nowak-Wegrzyn
J Allergy Clin Immunol 113:558-60. 2004 - Pathophysiology of food-induced anaphylaxisHeather Lemon-Mule
University of Alabama at Birmingham, Birmingham, AL 35209, USA
Curr Allergy Asthma Rep 8:201-8. 2008..With a greater understanding of the pathophysiology of food-induced anaphylaxis, novel approaches not only to identify those at risk, but to treat and ultimately prevent food-induced anaphylaxis, are on the horizon... - Primary care physicians' approach to food-induced anaphylaxis: a surveyJulie Wang
J Allergy Clin Immunol 114:689-91. 2004 - Bee pollen sensitivity in airborne pollen allergic individualsConstantinos Pitsios
Department of Allergology and Clinical Immunology, Laikon General Hospital, Athens, Greece
Ann Allergy Asthma Immunol 97:703-6. 2006..Physicians who practice alternative medicine often prescribe bee pollen as a food supplement and a treatment for various ailments... - Immunodeficiency and infections in ataxia-telangiectasiaAnna Nowak-Wegrzyn
Eudowood Division of Pediatric Allergy and Immunology, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287-3923, USA
J Pediatr 144:505-11. 2004..Cross-sectional analysis suggests that the immune defect is rarely progressive...
Research Grants
- Immunological Basis of Egg AllergyAnna Nowak Wegrzyn; Fiscal Year: 2007..Intestinal permeability will also be measured at 3 and 12 months, and correlated with oral egg challenge outcome, fecal and serum anti-egg IgE and anti-egg IgG antibody levels. ..