Research Topics
Species | Alexander NeumeisterSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
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Detail Information
Publications
The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand bindingJames W Murrough
Mood and Anxiety Disorders Program, Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, USA
Arch Gen Psychiatry 68:892-900. 2011..However, the specific role of the serotonin type 1B receptor has not been studied in patients with PTSD...
Age effects on serotonin receptor 1B as assessed by PETDavid Matuskey
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Nucl Med 53:1411-4. 2012..This paper addresses whether the availability of 5-hydroxytryptamine receptor 1B (5-HT(1B)) is seen to decrease with aging via PET imaging...- Reduced ventral striatal/ventral pallidal serotonin1B receptor binding potential in major depressive disorderJames W Murrough
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Psychopharmacology (Berl) 213:547-53. 2011..In particular, 5-HT(1B) heteroreceptors located within the striatum have been shown to play an essential role in antidepressant action... - Reduced amygdala serotonin transporter binding in posttraumatic stress disorderJames W Murrough
Mood and Anxiety Disorders Program, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
Biol Psychiatry 70:1033-8. 2011.... - Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging studyJonathan B Savitz
Mood and Anxiety Disorders Program, National Institutes of Health National Institute of Mental Health, Bethesda, Maryland, USA
Biol Psychiatry 69:336-43. 2011..We conducted the first magnetic resonance imaging analysis of habenula volume in MDD and bipolar disorder (BD)... - Plasma NPY concentrations during tryptophan and sham depletion in medication-free patients with remitted depressionChristoph Czermak
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
J Affect Disord 110:277-81. 2008..Neuropeptide Y (NPY) and serotonergic systems have been implicated in the pathophysiology of depression but have not yet been linked together... - Positron emission tomography shows elevated cannabinoid CB (1) receptor binding in men with alcohol dependenceAlexander Neumeister
Molecular Imaging Program, Department of Psychiatry and Radiology, New York University School of Medicine, New York, New York 10016, USA
Alcohol Clin Exp Res 36:2104-9. 2012..This is an important gap in the literature, because recent therapeutic developments suggest that these receptors could be targeted for the treatment for AD... - beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorderChristoph Czermak
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
Int J Neuropsychopharmacol 11:419-24. 2008..66, p=0.019, Bonferroni corrected). These findings not only suggest an involvement of beta2-nAChRs in the pathophysiology of PTSD but also raise the possibility that this receptor may be a novel molecular target for drug development... - Cognitive dysfunction in depression: neurocircuitry and new therapeutic strategiesJames W Murrough
Mood and Anxiety Disorders Program, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
Neurobiol Learn Mem 96:553-63. 2011..Finally, we highlight potential new pharmacological and non-pharmacological therapeutic strategies for MDD based on an evolving mechanistic understanding of the disorder... - Prefrontal cortical abnormalities in currently depressed versus currently remitted patients with major depressive disorderGiacomo Salvadore
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
Neuroimage 54:2643-51. 2011..Consistent with other neuroimaging and post-mortem neuropathological studies of MDD, we also found evidence of decreased white matter in patients with dMDD and rMDD... - Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilienceJohn H Krystal
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
Brain Res 1293:13-23. 2009.... - Tryptophan depletion and emotional processing in healthy volunteers at high risk for depressionAdriana Feder
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
Biol Psychiatry 69:804-7. 2011..The present study compared the effects of acute tryptophan depletion (ATD) on both an emotional processing and a planning task in never-depressed healthy volunteers at high and low familial risk for depression... 
Cerebral metabolic effects of intravenous glycine in healthy human subjectsAlexander Neumeister
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
J Clin Psychopharmacol 26:595-9. 2006....- Differential conditioned fear response predicts duloxetine treatment outcome in male veterans with PTSD: a pilot studyDeane E Aikins
Department of Psychiatry, Yale University, 300 George Street, New Haven, CT 06511, USA
Psychiatry Res 188:453-5. 2011..These data provide initial evidence of a putative biomarker of selective treatment response in PTSD... - Effects of yohimbine and hydrocortisone on panic symptoms, autonomic responses, and attention to threat in healthy adultsRoma A Vasa
Department of Psychiatry, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21211, USA
Psychopharmacology (Berl) 204:445-55. 2009..Few studies examine how these two neurochemical systems interact to influence anxiety and attention in humans...