Research Topics
| Hideo MakimuraSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
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Detail Information
Publications
Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intakeHideo Makimura
Fishberg Center for Neurobiology, Neurobiology of Aging Laboratories, Mount Sinai School of Medicine, One Gustave L, Levy Place, Box 1639, New York, New York 10029, USA
BMC Neurosci 3:18. 2002....
Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesityHideo Makimura
Fishberg Center for Neurobiology, Neurobiology of Aging Laboratories, Mount Sinai School of Medicine, One Gustave L, Levy Place, New York, New York 10029, USA
BMC Physiol 3:4. 2003..We hypothesized that adrenalectomy would increase hypothalamic POMC mRNA and reverse obese phenotypes in obesity due to a high-fat diet as it does in obesity due to leptin deficiency...
Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expressionHideo Makimura
Fishberg Center for Neurobiology, Neurobiology of Aging Laboratories, Mount Sinai School of Medicine, One Gustave L, Levy Place, New York, New York 10029, USA
BMC Physiol 3:5. 2003..To assess if elevated corticosterone is sufficient for the hypothalamic responses to fasting and diabetes, we assessed the effect of corticosterone pellets implanted for 48 hours on hypothalamic gene expression...
Adiponectin is stimulated by adrenalectomy in ob/ob mice and is highly correlated with resistin mRNAHideo Makimura
Neurobiology of Aging Laboratories, Fishberg Center for Neurobiology and Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, New York 10029, USA
Am J Physiol Endocrinol Metab 283:E1266-71. 2002..In addition, adiponectin and resistin expression were also highly correlated in diet-induced obese mice. The data support a role for adiponectin in mediating some effects of adrenalectomy on insulin sensitivity...
The physiological function of the agouti-related peptide gene: the control of weight and metabolic rateTooru M Mizuno
Fishberg Center for Neurobiology, Neurobiology of Aging Laboratories, Department of Geriatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
Ann Med 35:425-33. 2003....
Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesisCharles V Mobbs
Fishberg Center for Neuroscience Neurobiology of Aging Laboratories, P O Box 1639 and Department of Geriatrics, Mt Sinai School of Medicine, 1 Gustave Levy Pl, New York, NY 10029 6574, United States
Physiol Behav 85:3-23. 2005..In support of this glucoadipostatic hypothesis, the 5 present review examines evidence that obesity and the metabolic syndrome may be due to reduction in neuroendocrine sensitivity to glucose leading to increased metabolic efficiency...
Obesity over the life courseTooru Mizuno
Fishberg Center for Neurobiology, Neurobiology of Aging Laboratories, Department of Geriatrics, Mt. Sinai School of Medicine, New York, NY 10029, USA
Sci Aging Knowledge Environ 2004:re4. 2004..Indeed, these trends suggest that for the first time in modern history, the life expectancy of people in developed societies will begin to decrease, unless the rapid increase in the prevalence of obesity can be reversed...
Block the FAS, lose the fatCharles V Mobbs
Nat Med 8:335-6. 2002
