Xin Hua Liu

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi request reprint Interactive effect of interleukin-6 and prostaglandin E2 on osteoclastogenesis via the OPG/RANKL/RANK system
    Xin Hua Liu
    Department of Medicine, Box 1055, Mount Sinai School of Medicine, New York, NY 10029
    Ann N Y Acad Sci 1068:225-33. 2006
  2. ncbi request reprint Androgens promote preosteoblast differentiation via activation of the canonical Wnt signaling pathway
    Xin Hua Liu
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Ann N Y Acad Sci 1116:423-31. 2007
  3. ncbi request reprint Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system
    Xin Hua Liu
    Department of Medicine, Box 1055, Annenberg Building, Room 23 78, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, New York 10029, USA
    Endocrinology 146:1991-8. 2005
  4. ncbi request reprint Androgen-induced Wnt signaling in preosteoblasts promotes the growth of MDA-PCa-2b human prostate cancer cells
    Xin Hua Liu
    Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Cancer Res 67:5747-53. 2007
  5. ncbi request reprint Prostaglandin E(2) stimulates prostatic intraepithelial neoplasia cell growth through activation of the interleukin-6/GP130/STAT-3 signaling pathway
    Xin Hua Liu
    Department of Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Biochem Biophys Res Commun 290:249-55. 2002
  6. ncbi request reprint Cyclooxygenase-2 suppresses hypoxia-induced apoptosis via a combination of direct and indirect inhibition of p53 activity in a human prostate cancer cell line
    Xin Hua Liu
    Department of Medicine, Division of Endocrinology and Metabolism, and Urology, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Biol Chem 280:3817-23. 2005
  7. doi request reprint Prostaglandin E2 modulates components of the Wnt signaling system in bone and prostate cancer cells
    Xin Hua Liu
    Department of Medicine, Division of Endocrinology and Metabolism, Mount Sinai School of Medicine, New York, NY 10029, USA
    Biochem Biophys Res Commun 394:715-20. 2010
  8. doi request reprint Prostatic acid phosphatase is expressed in human prostate cancer bone metastases and promotes osteoblast differentiation
    Alexander Kirschenbaum
    Department of Urology, Mount Sinai School of Medicine, New York, New York, USA
    Ann N Y Acad Sci 1237:64-70. 2011
  9. ncbi request reprint Sex steroids have differential effects on growth and gene expression in primary human prostatic epithelial cell cultures derived from the peripheral versus transition zones
    Alexander Kirschenbaum
    Division of Endocrinology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Carcinogenesis 27:216-24. 2006
  10. ncbi request reprint Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line
    Xin Hua Liu
    Department of Medicine, Annenberg Building Room 23 78, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    J Biol Chem 277:50081-6. 2002

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Interactive effect of interleukin-6 and prostaglandin E2 on osteoclastogenesis via the OPG/RANKL/RANK system
    Xin Hua Liu
    Department of Medicine, Box 1055, Mount Sinai School of Medicine, New York, NY 10029
    Ann N Y Acad Sci 1068:225-33. 2006
    ..These findings provide evidence of interactive effect of PGE2 and IL-6 signaling pathways in osteoclastogenesis via effect on the OPG/RANKL/RANK system...
  2. ncbi request reprint Androgens promote preosteoblast differentiation via activation of the canonical Wnt signaling pathway
    Xin Hua Liu
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Ann N Y Acad Sci 1116:423-31. 2007
    ..These results suggest that androgens promote preosteoblastic differentiation via effects on the canonical Wnt signaling pathway...
  3. ncbi request reprint Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system
    Xin Hua Liu
    Department of Medicine, Box 1055, Annenberg Building, Room 23 78, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, New York 10029, USA
    Endocrinology 146:1991-8. 2005
    ..These findings provide evidence for cross-talk between the PGE(2) and IL-6 signaling enhance osteoclast differentiation via effects on the OPG/RANKL/RANK system in bone cells...
  4. ncbi request reprint Androgen-induced Wnt signaling in preosteoblasts promotes the growth of MDA-PCa-2b human prostate cancer cells
    Xin Hua Liu
    Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Cancer Res 67:5747-53. 2007
    ....
  5. ncbi request reprint Prostaglandin E(2) stimulates prostatic intraepithelial neoplasia cell growth through activation of the interleukin-6/GP130/STAT-3 signaling pathway
    Xin Hua Liu
    Department of Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Biochem Biophys Res Commun 290:249-55. 2002
    ..These data provide mechanistic evidence that increased expression of COX-2/PGE(2) contributes to prostate cancer development and progression via activation of the IL-6 signaling pathway...
  6. ncbi request reprint Cyclooxygenase-2 suppresses hypoxia-induced apoptosis via a combination of direct and indirect inhibition of p53 activity in a human prostate cancer cell line
    Xin Hua Liu
    Department of Medicine, Division of Endocrinology and Metabolism, and Urology, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Biol Chem 280:3817-23. 2005
    ..These data imply that COX-2-positive prostate cancer cells can have impaired p53 function even in the presence of wild-type p53 and that p53 activity can be restored in these cells via inhibition of COX-2 activity...
  7. doi request reprint Prostaglandin E2 modulates components of the Wnt signaling system in bone and prostate cancer cells
    Xin Hua Liu
    Department of Medicine, Division of Endocrinology and Metabolism, Mount Sinai School of Medicine, New York, NY 10029, USA
    Biochem Biophys Res Commun 394:715-20. 2010
    ..These data demonstrate that there are dose-dependent effects of PGE(2) on Wnt activation in osteoblast-lineage cells and Wnt-inhibitor expression in PCa cells which may have clinical implications in the management...
  8. doi request reprint Prostatic acid phosphatase is expressed in human prostate cancer bone metastases and promotes osteoblast differentiation
    Alexander Kirschenbaum
    Department of Urology, Mount Sinai School of Medicine, New York, New York, USA
    Ann N Y Acad Sci 1237:64-70. 2011
    ..Taken together, these data indicate that PAP is expressed in PCa bone metastases and may play a causal role in the osteoblastic phase of the disease...
  9. ncbi request reprint Sex steroids have differential effects on growth and gene expression in primary human prostatic epithelial cell cultures derived from the peripheral versus transition zones
    Alexander Kirschenbaum
    Division of Endocrinology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Carcinogenesis 27:216-24. 2006
    ..Finally, we demonstrate divergent responses to sex hormones in the two basal cell populations. The gene expression pattern in the PZ cells may partially explain the predominance of prostate cancer development in this region...
  10. ncbi request reprint Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line
    Xin Hua Liu
    Department of Medicine, Annenberg Building Room 23 78, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    J Biol Chem 277:50081-6. 2002
    ....
  11. ncbi request reprint The role of the interleukin-6/gp130 signaling pathway in bone metabolism
    Xin Hua Liu
    Department of Medicine, Division of Endocrinology, Diabetes and Bone Diseases, Mount Sinai School of Medicine, New York, New York 10029, USA
    Vitam Horm 74:341-55. 2006
  12. ncbi request reprint Alpha-fetoprotein triggers hepatoma cells escaping from immune surveillance through altering the expression of Fas/FasL and tumor necrosis factor related apoptosis-inducing ligand and its receptor of lymphocytes and liver cancer cells
    Meng Sen Li
    Department of Biochemistry, Hainan Medical College, Haikou, China
    World J Gastroenterol 11:2564-9. 2005
    ..To investigate the mechanism of alpha-fetoprotein (AFP) in escaping from the host immune surveillance of hepatocellular carcinoma...
  13. ncbi request reprint Signaling pathway involved in methionine enkephalin-promoted survival of lymphocytes infected by simian immunodeficiency virus in the early stage in vitro
    Ping Feng Li
    Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing 100083, China
    Int Immunopharmacol 4:79-90. 2004
    ..The results provide a further evidence for potential use of methionine enkephalin on the therapy of Acquired Immunodeficiency Syndrome (AIDS)...