Research Topics
Genomes and Genes | Xiajun LiSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
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Detail Information
Publications
Genomic imprinting is a parental effect established in mammalian germ cellsXiajun Li
Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York, USA
Curr Top Dev Biol 102:35-59. 2013..In germ cells, around midgestation, the DNA methylation imprint is erased and undergoes another round of the DNA methylation imprint cycle that includes erasure, resetting, restoration, and maintenance of differential DNA methylation...
A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprintsXiajun Li
Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
Dev Cell 15:547-57. 2008..The effects on genomic imprinting are consistent with the maternal-zygotic lethality of Zfp57 mutants...
Extending the maternal-zygotic effect with genomic imprintingXiajun Li
Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
Mol Hum Reprod 16:695-703. 2010....
Zinc finger protein ZFP57 requires its co-factor to recruit DNA methyltransferases and maintains DNA methylation imprint in embryonic stem cells via its transcriptional repression domainXiaopan Zuo
Black Family Stem Cell Institute, Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, New York 10029, USA
J Biol Chem 287:2107-18. 2012..These results suggest that ZFP57 may recruit DNA methyltransferases to its target regions to maintain DNA methylation imprint, and this interaction is likely facilitated by KAP1/TRIM28/TIF1β...
sel-7, a positive regulator of lin-12 activity, encodes a novel nuclear protein in Caenorhabditis elegansJiabin Chen
Department of Biochemistry and Molecular Biophysics, Molecular and Biophysical Studies, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
Genetics 166:151-60. 2004..8, that also interacts with SEL-8, a known component of the nuclear complex that forms upon LIN-12 activation. Our data suggest potential roles for SEL-7 in the assembly or function of this nuclear complex...
Identifying genes preferentially expressed in undifferentiated embryonic stem cellsXiajun Li
Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
BMC Cell Biol 8:37. 2007..The mechanism involved in the maintenance and differentiation of embryonic stem (ES) cells is incompletely understood...
