Y Jing

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi Boswellic acid acetate induces differentiation and apoptosis in leukemia cell lines
    Y Jing
    Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, People s Republic of China
    Leuk Res 23:43-50. 1999
  2. ncbi Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
    Y Jing
    Department of Medicine, Division of Medical Oncology, Mount Sinai School of Medicine, New York, NY 10029 6547, USA
    Blood 97:264-9. 2001
  3. ncbi Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway
    Y Jing
    Rochelle Belfer Chemotherapy Foundation Laboratory, Division of Neoplastic Diseases, Department of Medicine, Mount Sinai Medical Center, New York, NY, USA
    Blood 94:2102-11. 1999
  4. ncbi The design of selective and non-selective combination therapy for acute promyelocytic leukemia
    Y Jing
    Division of Hematology Oncology, Department of Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1178, New York, NY 10029 6547, USA
    Curr Top Microbiol Immunol 313:245-69. 2007
  5. ncbi Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis
    L Xia
    Division of Hematology Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA
    Leukemia 20:1009-16. 2006
  6. ncbi Synergistic transcriptional activation of the mouse urokinase plasminogen activator (uPA) gene and of its enhancer activator protein 1 (AP1) site by cAMP and retinoic acid
    R Mira-y-Lopez
    Mount Sinai School of Medicine, Department of Medicine, Box 1178, 1 Gustave L Levy Place, New York, NY10029, USA
    Biochem J 331:909-16. 1998
  7. ncbi Retinol conversion to retinoic acid is impaired in breast cancer cell lines relative to normal cells
    R Mira-y-Lopez
    Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA
    J Cell Physiol 185:302-9. 2000

Collaborators

Detail Information

Publications7

  1. ncbi Boswellic acid acetate induces differentiation and apoptosis in leukemia cell lines
    Y Jing
    Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, People s Republic of China
    Leuk Res 23:43-50. 1999
    ..Morphologic and DNA fragmentation analysis proved that BC-4 induced cell apoptosis. The dual apoptotic and differentiation effects of BC-4 suggest that it may be a powerful agent in the treatment of leukemia...
  2. ncbi Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
    Y Jing
    Department of Medicine, Division of Medical Oncology, Mount Sinai School of Medicine, New York, NY 10029 6547, USA
    Blood 97:264-9. 2001
    ..Although in vitro data do not always translate to in vivo response, toxicity and potential drug antagonism may be diminished by decreasing the concentration of As(2)O(3) when given at the same time with therapeutic levels of tRA...
  3. ncbi Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway
    Y Jing
    Rochelle Belfer Chemotherapy Foundation Laboratory, Division of Neoplastic Diseases, Department of Medicine, Mount Sinai Medical Center, New York, NY, USA
    Blood 94:2102-11. 1999
    ....
  4. ncbi The design of selective and non-selective combination therapy for acute promyelocytic leukemia
    Y Jing
    Division of Hematology Oncology, Department of Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1178, New York, NY 10029 6547, USA
    Curr Top Microbiol Immunol 313:245-69. 2007
    ..The combined effects of selective APL therapy (ATRA and As2O3) and/or non-selective chemotherapy in APL cells in vitro and their mechanisms in relation to clinical protocol design are discussed...
  5. ncbi Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis
    L Xia
    Division of Hematology Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA
    Leukemia 20:1009-16. 2006
    ..These data demonstrate that ATRA induction of Bfl-1/A1 in differentiated NB4 and HL-60 cells contributes to a loss of sensitivity to chemotherapy-induced apoptosis...
  6. ncbi Synergistic transcriptional activation of the mouse urokinase plasminogen activator (uPA) gene and of its enhancer activator protein 1 (AP1) site by cAMP and retinoic acid
    R Mira-y-Lopez
    Mount Sinai School of Medicine, Department of Medicine, Box 1178, 1 Gustave L Levy Place, New York, NY10029, USA
    Biochem J 331:909-16. 1998
    ..6 kb uPA-CAT fusion gene was also obtained using tRA and 100 nM PMA. We conclude that multiple cis elements, probably including the uPA enhancer AP1 site, mediate the tRA potentiation of uPA transcription...
  7. ncbi Retinol conversion to retinoic acid is impaired in breast cancer cell lines relative to normal cells
    R Mira-y-Lopez
    Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA
    J Cell Physiol 185:302-9. 2000
    ..We hypothesize that retinol bioactivity is impaired in breast cancer cells that cannot synthesize RA. In preliminary support of this hypothesis, we found that retinol (0.5-2 microM) inhibited MCF-10F but not T47D or MCF-7 cell growth...