M C Iannuzzi

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. pmc Reduction of sample heterogeneity through use of population substructure: an example from a population of African American families with sarcoidosis
    Cheryl L Thompson
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106 7281, USA
    Am J Hum Genet 79:606-13. 2006
  2. pmc Genetics of sarcoidosis: candidate genes and genome scans
    Michael C Iannuzzi
    Division of Pulmonary, Critical Care and Sleep Medicine, Mount Sinai School of Medicine, New York, New York, USA
    Proc Am Thorac Soc 4:108-16. 2007
  3. ncbi request reprint Sarcoidosis
    Michael C Iannuzzi
    Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, USA
    N Engl J Med 357:2153-65. 2007
  4. ncbi request reprint Genetics of sarcoidosis
    Michael C Iannuzzi
    Division of Pulmonary, Critical Care and Sleep Medicine, The Mount Sinai School of Medicine, New York, New York 10029, USA
    Semin Respir Crit Care Med 28:15-21. 2007
  5. ncbi request reprint Genome-wide search for sarcoidosis susceptibility genes in African Americans
    M C Iannuzzi
    Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Genes Immun 6:509-18. 2005
  6. ncbi request reprint HLA and environmental interactions in sarcoidosis
    M D Rossman
    Division of Pulmonary, Allergy and Critical Care, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104 6160, USA
    Sarcoidosis Vasc Diffuse Lung Dis 25:125-32. 2008
  7. ncbi request reprint A sarcoidosis genetic linkage consortium: the sarcoidosis genetic analysis (SAGA) study
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
    Sarcoidosis Vasc Diffuse Lung Dis 22:115-22. 2005
  8. ncbi request reprint Pulmonary and psychosocial findings at enrollment in the ACCESS study
    Henry Yeager
    Pulmonary, Critical Care, and Sleep Medicine, Georgetown University Medical Center, Washington, DC 20057, USA
    Sarcoidosis Vasc Diffuse Lung Dis 22:147-53. 2005
  9. pmc The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI, USA
    Am J Hum Genet 77:491-9. 2005
  10. ncbi request reprint Ethnic disparities in the treatment of stage I non-small cell lung cancer
    Juan P Wisnivesky
    Divison of General Internal Medicine, Department of Health Policy, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1087, New York, New York 10029, USA
    Am J Respir Crit Care Med 171:1158-63. 2005

Collaborators

Detail Information

Publications35

  1. pmc Reduction of sample heterogeneity through use of population substructure: an example from a population of African American families with sarcoidosis
    Cheryl L Thompson
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106 7281, USA
    Am J Hum Genet 79:606-13. 2006
    ..Our findings support the presence of sarcoidosis-susceptibility genes in regions identified elsewhere but indicate that these genes are likely to be ancestry specific...
  2. pmc Genetics of sarcoidosis: candidate genes and genome scans
    Michael C Iannuzzi
    Division of Pulmonary, Critical Care and Sleep Medicine, Mount Sinai School of Medicine, New York, New York, USA
    Proc Am Thorac Soc 4:108-16. 2007
    ..The cause of sarcoidosis has been elusive, but genetics provides one of the few promising avenues to further our understanding. We review the association studies and genome scans used to identify the genes involved in sarcoidosis...
  3. ncbi request reprint Sarcoidosis
    Michael C Iannuzzi
    Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, USA
    N Engl J Med 357:2153-65. 2007
  4. ncbi request reprint Genetics of sarcoidosis
    Michael C Iannuzzi
    Division of Pulmonary, Critical Care and Sleep Medicine, The Mount Sinai School of Medicine, New York, New York 10029, USA
    Semin Respir Crit Care Med 28:15-21. 2007
    ..Follow-up studies on chromosome 6 identified the BTNL2 gene, a B7 family costimulatory molecule to be associated with sarcoidosis. Advances in genotyping and statistical analysis are helping to elucidate the genetics of sarcoidosis...
  5. ncbi request reprint Genome-wide search for sarcoidosis susceptibility genes in African Americans
    M C Iannuzzi
    Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Genes Immun 6:509-18. 2005
    ..Fine mapping of the linked regions, particularly on chromosome 5q, should help to refine linkage signals and guide further sarcoidosis candidate gene investigation...
  6. ncbi request reprint HLA and environmental interactions in sarcoidosis
    M D Rossman
    Division of Pulmonary, Allergy and Critical Care, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104 6160, USA
    Sarcoidosis Vasc Diffuse Lung Dis 25:125-32. 2008
    ..Future studies in defined phenotypes of sarcoidosis may be necessary to define environmental and genetic associations with sarcoidosis...
  7. ncbi request reprint A sarcoidosis genetic linkage consortium: the sarcoidosis genetic analysis (SAGA) study
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
    Sarcoidosis Vasc Diffuse Lung Dis 22:115-22. 2005
    ..In the United States of America, African Americans have a higher sarcoidosis incidence and suffer greater morbidity than Caucasians...
  8. ncbi request reprint Pulmonary and psychosocial findings at enrollment in the ACCESS study
    Henry Yeager
    Pulmonary, Critical Care, and Sleep Medicine, Georgetown University Medical Center, Washington, DC 20057, USA
    Sarcoidosis Vasc Diffuse Lung Dis 22:147-53. 2005
    ..To assess lung involvement and the association of demographic and psychosocial factors with respiratory health in 736 persons with sarcoidosis at enrollment in A Case Control Etiologic Study of Sarcoidosis (ACCESS)...
  9. pmc The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI, USA
    Am J Hum Genet 77:491-9. 2005
    ..Our results underscore the complexity of genetic risk for sarcoidosis emanating from the MHC region...
  10. ncbi request reprint Ethnic disparities in the treatment of stage I non-small cell lung cancer
    Juan P Wisnivesky
    Divison of General Internal Medicine, Department of Health Policy, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1087, New York, New York 10029, USA
    Am J Respir Crit Care Med 171:1158-63. 2005
    ..Important variations exist in the treatment of non-small cell lung cancer. Because resection is the most effective treatment for patients with early disease, disparities in surgical rates can generate considerable differences in outcomes...
  11. ncbi request reprint Comparison of sarcoidosis phenotypes among affected African-American siblings
    Marc A Judson
    Division of Pulmonary and Critical Care Medicine CSB 812, Medical University of South Carolina, Charleston, SC 29425, USA
    Chest 130:855-62. 2006
    ..To test the hypothesis that sibling pairs, who share genes and environmental exposures, might have similar phenotypic expressions of sarcoidosis beyond what would be expected by chance alone...
  12. pmc Validity of clinical prediction rules for isolating inpatients with suspected tuberculosis. A systematic review
    Juan P Wisnivesky
    Division of General Internal Medicine, Mount Sinai Medical Center, New York, NY USA
    J Gen Intern Med 20:947-52. 2005
    ..The purpose of this study is to systematically review decision rules to predict the patient's risk for active pulmonary TB at the time of admission to the hospital...
  13. ncbi request reprint Prognosis of Stage II non-small cell lung cancer according to tumor and nodal status at diagnosis
    Juan P Wisnivesky
    Division of General Internal Medicine, Mount Sinai School of Medicine One Gustave L Levy Place, Box 1087, NY 10029, USA
    Lung Cancer 49:181-6. 2005
    ..To evaluate the prognostic significance of tumor and node status among patients with Stage II non-small cell lung cancer using a population-based national database...
  14. ncbi request reprint Photocopier exposure and risk of sarcoidosis in African-American sibs
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Sarcoidosis Vasc Diffuse Lung Dis 21:49-55. 2004
    ..This finding, and case reports of granulomatous lung disease in patients with photocopier toner dust exposure, led us to hypothesize that sarcoidosis risk may increase as a result of photocopier exposure...
  15. ncbi request reprint Advances in the genetics of sarcoidosis
    Michael C Iannuzzi
    Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai Medical Center, 1 Gustave L Levy Place, Box 1232, New York, NY 10029, USA
    Proc Am Thorac Soc 4:457-60. 2007
    ..Certain chromosomal regions were also found linked to specific phenotypes. Follow-up fine mapping studies of the linked regions are underway...
  16. ncbi request reprint The distribution of long range admixture linkage disequilibrium in an African-American population
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Mich 48202, USA
    Hum Hered 53:187-96. 2002
    ..To better understand the effect of admixture on long range linkage disequilibrium (LD), we characterized extended LD in gene-rich regions of an African-American population...
  17. ncbi request reprint The major histocompatibility complex gene region and sarcoidosis susceptibility in African Americans
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology and Division of Pulmonary and Critical Care Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA
    Am J Respir Crit Care Med 167:444-9. 2003
    ....
  18. ncbi request reprint Sarcoidosis susceptibility and resistance HLA-DQB1 alleles in African Americans
    Michael C Iannuzzi
    Division of Pulmonary and Critical Care Medicine, Mount Sinai Medical Center, One Gustave Levy Place, Box 1232, NY, NY 10029, USA
    Am J Respir Crit Care Med 167:1225-31. 2003
    ..Major differences in the amino acid sequences encoded by *0201 and *0602 alleles exist, which may explain the differential effects these alleles have on sarcoidosis susceptibility and progression in African Americans...
  19. ncbi request reprint Occupational risk factors for sarcoidosis in African-American siblings
    Gena P Kucera
    Josephine Ford Cancer Center, Henry Ford Health System, Detroit, MI 48202, USA
    Chest 123:1527-35. 2003
    ..To determine whether certain occupations and occupationally related exposures were associated with a history of sarcoidosis in African-American siblings...
  20. ncbi request reprint Epidemiology of sarcoidosis: recent advances and future prospects
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Semin Respir Crit Care Med 28:22-35. 2007
    ..In summary, the epidemiology of sarcoidosis has a promising future that should eventually provide the answers to the etiologic origins of this complex disease...
  21. ncbi request reprint Two year prognosis of sarcoidosis: the ACCESS experience
    Marc A Judson
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    Sarcoidosis Vasc Diffuse Lung Dis 20:204-11. 2003
    ..Several factors associated with improved or worse outcome over two years were identified...
  22. ncbi request reprint Clara cell protein in sarcoidosis: another job for the respiratory tract protector?
    Michael C Iannuzzi
    Am J Respir Crit Care Med 169:143-4. 2004
  23. ncbi request reprint Genetic characterization and fine mapping of susceptibility loci for sarcoidosis in African Americans on chromosome 5
    Courtney Gray-McGuire
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA
    Hum Genet 120:420-30. 2006
    ..2. We conclude that multiple susceptibility loci for sarcoidosis exist in African Americans and that some may have interdependent effects on disease pathogenesis...
  24. ncbi request reprint Reverse phenotyping in sarcoidosis
    Michael C Iannuzzi
    Am J Respir Crit Care Med 175:4-5. 2007
  25. ncbi request reprint Results of 188 whole-body fluorodeoxyglucose positron emission tomography scans in 137 patients with sarcoidosis
    Alvin S Teirstein
    Divisions of Pulmonary Medicine, Mount Sinai Medical Center, New York, NY, USA
    Chest 132:1949-53. 2007
    ..To study the role of whole-body 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) scans in the identification of occult biopsy sites and reversible granulomatous disease in patients with sarcoidosis...
  26. ncbi request reprint Job and industry classifications associated with sarcoidosis in A Case-Control Etiologic Study of Sarcoidosis (ACCESS)
    Juliana Barnard
    Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA
    J Occup Environ Med 47:226-34. 2005
    ..To determine whether specific occupations and industries may be associated with sarcoidosis...
  27. pmc Genetic polymorphisms in lung disease: bandwagon or breakthrough?
    Michael C Iannuzzi
    Division of Pulmonary, Critical Care, Henry Ford Health System, Detroit, Michigan, USA
    Respir Res 3:15. 2002
    ..Several pitfalls are commonly encountered in studying genetic polymorphisms, and this article points out criteria that should be applied to design high-quality genetic polymorphism studies...
  28. ncbi request reprint Nomination of a candidate susceptibility gene in sarcoidosis: the complement receptor 1 gene
    Michael C Iannuzzi
    Division of Pulmonary, Critical Care, and Allergy, Henry Ford Health System, Detroit, Michigan 48202, USA
    Am J Respir Cell Mol Biol 27:3-7. 2002
  29. ncbi request reprint Use of fluticasone in acute symptomatic pulmonary sarcoidosis
    Robert P Baughman
    Department of Internal Medicine, University of Cincinnati Medical Center, OH 45267 0565, USA
    Sarcoidosis Vasc Diffuse Lung Dis 19:198-204. 2002
    ..Inhaled corticosteroids have been used with variable success in sarcoidosis. The role of the inhaled corticosteroid fluticasone in symptomatic pulmonary patients was studied...
  30. pmc HLA-DRB1*1101: a significant risk factor for sarcoidosis in blacks and whites
    Milton D Rossman
    Pulmonary, Allergy and Critical Care Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 19104, USA
    Am J Hum Genet 73:720-35. 2003
    ..These studies confirm a genetic predisposition for sarcoidosis and present evidence for the allelic variation at the HLA-DRB1 locus as a major contributor...
  31. ncbi request reprint Sarcoidosis and human leukocyte antigen class I and II genes: it takes two to tango?
    Benjamin A Rybicki
    Am J Respir Crit Care Med 169:665-6. 2004
  32. ncbi request reprint Future directions in sarcoidosis research: summary of an NHLBI working group
    William J Martin
    College of Medicine, University of Cincinnati, Cincinnati, OH, USA
    Am J Respir Crit Care Med 170:567-71. 2004
    ....
  33. ncbi request reprint A case control etiologic study of sarcoidosis: environmental and occupational risk factors
    Lee S Newman
    National Jewish Medical and Research Center and Univresity of Colorado Health Scienes Center, Denver, CO 80206, USA
    Am J Respir Crit Care Med 170:1324-30. 2004
    ..65, CI 0.51-0.82). The study did not identify a single, predominant cause of sarcoidosis. We identified several exposures associated with sarcoidosis risk, including insecticides, agricultural employment, and microbial bioaerosols...
  34. pmc Pharmacy data for tuberculosis surveillance and assessment of patient management
    Deborah S Yokoe
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Emerg Infect Dis 10:1426-31. 2004
    ..Pharmacy data can help public health officials to find TB cases and assess their management in populations that receive care in the private sector...
  35. ncbi request reprint Prospects of admixture linkage disequilibrium mapping in the African-American genome
    Benjamin A Rybicki
    Department of Biostatistics, Henry Ford Health System, Detroit, Michigan 48202, USA
    Cytometry 47:63-5. 2002