Yasmin Hurd

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors
    Yasmin L Hurd
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 11:855-62. 2006
  2. ncbi Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    Stella Dracheva
    James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Neuropsychopharmacology 34:2237-51. 2009
  3. ncbi Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    Ian Maze
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA
    Science 327:213-6. 2010
  4. ncbi Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    Quincey LaPlant
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    Nat Neurosci 13:1137-43. 2010
  5. ncbi Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    Yanhua Ren
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Neurosci 29:14764-9. 2009
  6. ncbi Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression
    Andrej Nikoshkov
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:786-91. 2008
  7. ncbi Heroin abuse is characterized by discrete mesolimbic dopamine and opioid abnormalities and exaggerated nuclear receptor-related 1 transcriptional decline with age
    Monika Cs Horvath
    Department of Forensic Medicine, Semmelweis University, H 1085, Budapest, Hungary
    J Neurosci 27:13371-5. 2007
  8. ncbi Mu opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers
    Katarina Drakenberg
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:7883-8. 2006
  9. ncbi Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor
    Florence Merg
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, Illkirch, France
    J Neurochem 97:292-301. 2006
  10. ncbi Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor
    Paul Berghuis
    Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Scheeles väg 1 A1, Karolinska Institutet, S 17177 Stockholm, Sweden
    Proc Natl Acad Sci U S A 102:19115-20. 2005

Research Grants

  1. Dynorphin /kappa mesolimbic system in heroin abuse
    Yasmin Hurd; Fiscal Year: 2007
  2. Effects of Drug Abuse on Human Neurodevelopment
    Yasmin Hurd; Fiscal Year: 2007
  3. Neurodevelopmental Effects of Adolescent Cannabis Use
    Yasmin Hurd; Fiscal Year: 2007
  4. The Opioid mesolimbic system in heroin abuse
    Yasmin Hurd; Fiscal Year: 2009
  5. The neuronal basis of cannabis-induced developmental deficits in the CNS
    Yasmin L Hurd; Fiscal Year: 2010
  6. MOLECULAR EFFECT OF DRUG ABUSE ON HUMAN NEURODEVELOPMENT
    Yasmin Hurd; Fiscal Year: 2001
  7. The Opioid mesolimbic system in heroin abuse
    Yasmin L Hurd; Fiscal Year: 2010

Collaborators

  • E J Nestler
  • S Dracheva
  • WILLIAM M BYNE
  • Scott J Russo
  • Jian Feng
  • JOHN HENRY MORRISON
  • Amelia Eisch
  • Mohamed Kabbaj
  • Brigitte L Kieffer
  • Yanhua Ren
  • Monika Cs Horvath
  • Ian Maze
  • Quincey LaPlant
  • Andrej Nikoshkov
  • Eva Keller
  • Katarina Drakenberg
  • David M Dietz
  • Ezekiell Mouzon
  • William Renthal
  • Rachael L Neve
  • Herbert E Covington
  • Xinyu Wang
  • Florence Merg
  • Georgy Bakalkin
  • Paul Berghuis
  • Max Mechanic
  • Paul Greengard
  • Hui Wang
  • Brandon L Warren
  • Alexander Tarakhovsky
  • Fiona Hollis
  • Dani Dumitriu
  • Emily L Watts
  • Gouping Fan
  • Ronald S Oosting
  • Carlos A Bolanos
  • Guanghua Xiao
  • Stephen J Haggarty
  • Vincent Vialou
  • Sergio D Iniguez
  • Anne Schaefer
  • Srihari C Sampath
  • Ja Wook Koo
  • Michele A Noonan
  • John Whittard
  • Claudia V Morris
  • Alejandro Higuera-Matas
  • Viktor Kovari
  • Katalin Majtenyi
  • Gabor G Kovacs
  • Dominique Filliol
  • Ivan Usynin
  • Sadia Rahman
  • Kati Saarelainen
  • Pernilla Fagergren
  • Tatjana Yakovleva
  • Niklas Bark
  • Anna Gharibyan
  • Igor Bazov
  • Jovan Rajs
  • Ingrid Nylander
  • Fernanda Ledda
  • Ken Mackie
  • Marton B Dobszay
  • Patrik Ernfors
  • Sabrina Spano
  • Tibor Harkany
  • Gustavo Paratcha
  • Gunnar Schulte
  • Kyle M Sousa

Detail Information

Publications10

  1. ncbi Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors
    Yasmin L Hurd
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 11:855-62. 2006
    ..This article provides an overview of genetic polymorphisms linked to these neurobiological systems, particularly in relation to psychostimulant- and opioid-addiction vulnerability...
  2. ncbi Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    Stella Dracheva
    James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Neuropsychopharmacology 34:2237-51. 2009
    ..No differences in the 5-HT(2C)R expression were detected between the behavioral phenotypes. However, editing was higher in the PFC of HRs vs LRs, implicating this region in the pathophysiology of drug abuse liability...
  3. ncbi Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    Ian Maze
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA
    Science 327:213-6. 2010
    ....
  4. ncbi Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    Quincey LaPlant
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    Nat Neurosci 13:1137-43. 2010
    ..These data establish the importance of Dnmt3a in the NAc in regulating cellular and behavioral plasticity to emotional stimuli...
  5. ncbi Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    Yanhua Ren
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Neurosci 29:14764-9. 2009
    ..The findings highlight the unique contributions of distinct cannabis constituents to addiction vulnerability and suggest that CBD may be a potential treatment for heroin craving and relapse...
  6. ncbi Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression
    Andrej Nikoshkov
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:786-91. 2008
    ....
  7. ncbi Heroin abuse is characterized by discrete mesolimbic dopamine and opioid abnormalities and exaggerated nuclear receptor-related 1 transcriptional decline with age
    Monika Cs Horvath
    Department of Forensic Medicine, Semmelweis University, H 1085, Budapest, Hungary
    J Neurosci 27:13371-5. 2007
    ....
  8. ncbi Mu opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers
    Katarina Drakenberg
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:7883-8. 2006
    ..Taken together, alterations in opioid neuropeptide systems might underlie enhanced opiate abuse vulnerability apparent in 118G individuals...
  9. ncbi Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor
    Florence Merg
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, Illkirch, France
    J Neurochem 97:292-301. 2006
    ..Collectively, the high potency and efficacy and the relative abundance suggest that Big Dyn may play a role in the KOR-mediated activation of G proteins...
  10. ncbi Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor
    Paul Berghuis
    Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Scheeles väg 1 A1, Karolinska Institutet, S 17177 Stockholm, Sweden
    Proc Natl Acad Sci U S A 102:19115-20. 2005
    ..Moreover, eCBs use TrkB receptor-dependent signaling pathways to regulate subtype-selective interneuron migration and specification...

Research Grants28

  1. Dynorphin /kappa mesolimbic system in heroin abuse
    Yasmin Hurd; Fiscal Year: 2007
    ..By characterizing the DYN/kappa-related mesolimbic circuits in human heroin users, it might also be possible to develop even more effective therapeutic interventions for opiate abuse. ..
  2. Effects of Drug Abuse on Human Neurodevelopment
    Yasmin Hurd; Fiscal Year: 2007
    ..abstract_text> ..
  3. Neurodevelopmental Effects of Adolescent Cannabis Use
    Yasmin Hurd; Fiscal Year: 2007
    ..abstract_text> ..
  4. The Opioid mesolimbic system in heroin abuse
    Yasmin Hurd; Fiscal Year: 2009
    ..As such targeted for medications can be development. ..
  5. The neuronal basis of cannabis-induced developmental deficits in the CNS
    Yasmin L Hurd; Fiscal Year: 2010
    ..Such insights are of significant importance considering that marijuana is the most commonly used illicit drug by pregnant women and young women of childbearing age. ..
  6. MOLECULAR EFFECT OF DRUG ABUSE ON HUMAN NEURODEVELOPMENT
    Yasmin Hurd; Fiscal Year: 2001
    ....
  7. The Opioid mesolimbic system in heroin abuse
    Yasmin L Hurd; Fiscal Year: 2010
    ..As such targeted for medications can be development. ..