Yasmin Hurd

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi request reprint Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors
    Yasmin L Hurd
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 11:855-62. 2006
  2. doi request reprint Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage
    Yasmin L Hurd
    Departments of Psychiatry, Neuroscience and Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY, USA
    Neurotherapeutics 12:807-15. 2015
  3. pmc Cannabis-dependence risk relates to synergism between neuroticism and proenkephalin SNPs associated with amygdala gene expression: case-control study
    Didier Jutras-Aswad
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America
    PLoS ONE 7:e39243. 2012
  4. pmc Trajectory of adolescent cannabis use on addiction vulnerability
    Yasmin L Hurd
    Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA James J Peters Veterans Administration, Bronx, NY, USA Electronic address
    Neuropharmacology 76:416-24. 2014
  5. pmc Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    Stella Dracheva
    James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Neuropsychopharmacology 34:2237-51. 2009
  6. pmc Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    Ian Maze
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA
    Science 327:213-6. 2010
  7. pmc Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    Quincey LaPlant
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    Nat Neurosci 13:1137-43. 2010
  8. pmc Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene
    Janine D Flory
    Department of Psychology, Queens College and The Graduate Center, City University of New York, New York, NY, USA
    Biol Psychol 88:51-6. 2011
  9. pmc Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    Yanhua Ren
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Neurosci 29:14764-9. 2009
  10. pmc Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression
    Andrej Nikoshkov
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:786-91. 2008

Research Grants

Collaborators

  • E J Nestler
  • Panos Roussos
  • Carolyn L Pytte
  • Janine D Flory
  • Jian Feng
  • WILLIAM M BYNE
  • JOHN HENRY MORRISON
  • S Dracheva
  • Amelia Eisch
  • Mohamed Kabbaj
  • Scott J Russo
  • Brigitte L Kieffer
  • Panos Bitsios
  • Yanhua Ren
  • Monika Cs Horvath
  • Quincey LaPlant
  • Ian Maze
  • Andrej Nikoshkov
  • Eva Keller
  • Katarina Drakenberg
  • Didier Jutras-Aswad
  • Ezekiell Mouzon
  • William Renthal
  • Herbert E Covington
  • David M Dietz
  • Rachael L Neve
  • Xinyu Wang
  • Florence Merg
  • Georgy Bakalkin
  • Paul Berghuis
  • Xun Liu
  • Georgia Yiannoulos
  • Michelle M Jacobs
  • Yoko Nomura
  • Carlos A Bolanos
  • Dani Dumitriu
  • Srihari C Sampath
  • Ronald S Oosting
  • Ja Wook Koo
  • Vincent Vialou
  • Stephen J Haggarty
  • Max Mechanic
  • Brandon L Warren
  • Emily L Watts
  • Gouping Fan
  • Michele A Noonan
  • Alexander Tarakhovsky
  • Fiona Hollis
  • Anne Schaefer
  • Hui Wang
  • Guanghua Xiao
  • Paul Greengard
  • Sergio D Iniguez
  • John Whittard
  • Alejandro Higuera-Matas
  • Claudia V Morris
  • Katalin Majtenyi
  • Gabor G Kovacs
  • Viktor Kovari
  • Ivan Usynin
  • Dominique Filliol
  • Niklas Bark
  • Tatjana Yakovleva
  • Sadia Rahman
  • Anna Gharibyan
  • Igor Bazov
  • Ingrid Nylander
  • Pernilla Fagergren
  • Jovan Rajs
  • Kati Saarelainen
  • Patrik Ernfors
  • Fernanda Ledda
  • Gunnar Schulte
  • Ken Mackie
  • Sabrina Spano
  • Marton B Dobszay
  • Gustavo Paratcha
  • Tibor Harkany
  • Kyle M Sousa

Detail Information

Publications15

  1. ncbi request reprint Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors
    Yasmin L Hurd
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 11:855-62. 2006
    ..This article provides an overview of genetic polymorphisms linked to these neurobiological systems, particularly in relation to psychostimulant- and opioid-addiction vulnerability...
  2. doi request reprint Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage
    Yasmin L Hurd
    Departments of Psychiatry, Neuroscience and Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY, USA
    Neurotherapeutics 12:807-15. 2015
    ..As the legal landscape for medical marijuana unfolds, it is important to distinguish it from "medical CBD" and other specific cannabinoids, that can more appropriately be used to maximize the medicinal potential of the marijuana plant...
  3. pmc Cannabis-dependence risk relates to synergism between neuroticism and proenkephalin SNPs associated with amygdala gene expression: case-control study
    Didier Jutras-Aswad
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America
    PLoS ONE 7:e39243. 2012
    ..Whether polymorphisms of these genes are associated with cannabis dependence and related behavioral traits is unknown...
  4. pmc Trajectory of adolescent cannabis use on addiction vulnerability
    Yasmin L Hurd
    Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA James J Peters Veterans Administration, Bronx, NY, USA Electronic address
    Neuropharmacology 76:416-24. 2014
    ..This article is part of a Special Issue entitled 'NIDA 40th Anniversary Issue'...
  5. pmc Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    Stella Dracheva
    James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Neuropsychopharmacology 34:2237-51. 2009
    ..No differences in the 5-HT(2C)R expression were detected between the behavioral phenotypes. However, editing was higher in the PFC of HRs vs LRs, implicating this region in the pathophysiology of drug abuse liability...
  6. pmc Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    Ian Maze
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA
    Science 327:213-6. 2010
    ....
  7. pmc Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    Quincey LaPlant
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    Nat Neurosci 13:1137-43. 2010
    ..These data establish the importance of Dnmt3a in the NAc in regulating cellular and behavioral plasticity to emotional stimuli...
  8. pmc Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene
    Janine D Flory
    Department of Psychology, Queens College and The Graduate Center, City University of New York, New York, NY, USA
    Biol Psychol 88:51-6. 2011
    ..g., drug use, sexual activity)...
  9. pmc Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    Yanhua Ren
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Neurosci 29:14764-9. 2009
    ..The findings highlight the unique contributions of distinct cannabis constituents to addiction vulnerability and suggest that CBD may be a potential treatment for heroin craving and relapse...
  10. pmc Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression
    Andrej Nikoshkov
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:786-91. 2008
    ....
  11. ncbi request reprint Heroin abuse is characterized by discrete mesolimbic dopamine and opioid abnormalities and exaggerated nuclear receptor-related 1 transcriptional decline with age
    Monika Cs Horvath
    Department of Forensic Medicine, Semmelweis University, H 1085, Budapest, Hungary
    J Neurosci 27:13371-5. 2007
    ....
  12. pmc Mu opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers
    Katarina Drakenberg
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:7883-8. 2006
    ..Taken together, alterations in opioid neuropeptide systems might underlie enhanced opiate abuse vulnerability apparent in 118G individuals...
  13. ncbi request reprint Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor
    Florence Merg
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, Illkirch, France
    J Neurochem 97:292-301. 2006
    ..Collectively, the high potency and efficacy and the relative abundance suggest that Big Dyn may play a role in the KOR-mediated activation of G proteins...
  14. pmc Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor
    Paul Berghuis
    Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Scheeles väg 1 A1, Karolinska Institutet, S 17177 Stockholm, Sweden
    Proc Natl Acad Sci U S A 102:19115-20. 2005
    ..Moreover, eCBs use TrkB receptor-dependent signaling pathways to regulate subtype-selective interneuron migration and specification...

Research Grants2

  1. Effects of Drug Abuse on Human Neurodevelopment
    Yasmin Hurd; Fiscal Year: 2007
    ..abstract_text> ..
  2. Neurodevelopmental Effects of Adolescent Cannabis Use
    Yasmin Hurd; Fiscal Year: 2008
    ..abstract_text> ..