Yasmin Hurd

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi request reprint Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors
    Yasmin L Hurd
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 11:855-62. 2006
  2. pmc Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    Stella Dracheva
    James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Neuropsychopharmacology 34:2237-51. 2009
  3. pmc Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    Ian Maze
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA
    Science 327:213-6. 2010
  4. pmc Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    Quincey LaPlant
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    Nat Neurosci 13:1137-43. 2010
  5. pmc Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    Yanhua Ren
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Neurosci 29:14764-9. 2009
  6. pmc Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression
    Andrej Nikoshkov
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:786-91. 2008
  7. ncbi request reprint Heroin abuse is characterized by discrete mesolimbic dopamine and opioid abnormalities and exaggerated nuclear receptor-related 1 transcriptional decline with age
    Monika Cs Horvath
    Department of Forensic Medicine, Semmelweis University, H 1085, Budapest, Hungary
    J Neurosci 27:13371-5. 2007
  8. pmc Mu opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers
    Katarina Drakenberg
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:7883-8. 2006
  9. ncbi request reprint Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor
    Florence Merg
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, Illkirch, France
    J Neurochem 97:292-301. 2006
  10. pmc Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor
    Paul Berghuis
    Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Scheeles väg 1 A1, Karolinska Institutet, S 17177 Stockholm, Sweden
    Proc Natl Acad Sci U S A 102:19115-20. 2005

Collaborators

  • E J Nestler
  • S Dracheva
  • WILLIAM M BYNE
  • Scott J Russo
  • Jian Feng
  • JOHN HENRY MORRISON
  • Amelia Eisch
  • Mohamed Kabbaj
  • Brigitte L Kieffer
  • Yanhua Ren
  • Monika Cs Horvath
  • Quincey LaPlant
  • Ian Maze
  • Andrej Nikoshkov
  • Eva Keller
  • Katarina Drakenberg
  • David M Dietz
  • Rachael L Neve
  • Ezekiell Mouzon
  • William Renthal
  • Herbert E Covington
  • Xinyu Wang
  • Georgy Bakalkin
  • Florence Merg
  • Paul Berghuis
  • Guanghua Xiao
  • Gouping Fan
  • Ronald S Oosting
  • Ja Wook Koo
  • Max Mechanic
  • Carlos A Bolanos
  • Stephen J Haggarty
  • Paul Greengard
  • Hui Wang
  • Brandon L Warren
  • Dani Dumitriu
  • Emily L Watts
  • Fiona Hollis
  • Vincent Vialou
  • Srihari C Sampath
  • Sergio D Iniguez
  • Michele A Noonan
  • Alexander Tarakhovsky
  • Anne Schaefer
  • John Whittard
  • Alejandro Higuera-Matas
  • Claudia V Morris
  • Viktor Kovari
  • Gabor G Kovacs
  • Katalin Majtenyi
  • Tatjana Yakovleva
  • Niklas Bark
  • Pernilla Fagergren
  • Jovan Rajs
  • Anna Gharibyan
  • Ivan Usynin
  • Kati Saarelainen
  • Ingrid Nylander
  • Igor Bazov
  • Sadia Rahman
  • Dominique Filliol
  • Patrik Ernfors
  • Fernanda Ledda
  • Ken Mackie
  • Tibor Harkany
  • Gustavo Paratcha
  • Marton B Dobszay
  • Sabrina Spano
  • Gunnar Schulte
  • Kyle M Sousa

Detail Information

Publications10

  1. ncbi request reprint Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors
    Yasmin L Hurd
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 11:855-62. 2006
    ..This article provides an overview of genetic polymorphisms linked to these neurobiological systems, particularly in relation to psychostimulant- and opioid-addiction vulnerability...
  2. pmc Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    Stella Dracheva
    James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Neuropsychopharmacology 34:2237-51. 2009
    ..No differences in the 5-HT(2C)R expression were detected between the behavioral phenotypes. However, editing was higher in the PFC of HRs vs LRs, implicating this region in the pathophysiology of drug abuse liability...
  3. pmc Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    Ian Maze
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA
    Science 327:213-6. 2010
    ....
  4. pmc Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    Quincey LaPlant
    Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    Nat Neurosci 13:1137-43. 2010
    ..These data establish the importance of Dnmt3a in the NAc in regulating cellular and behavioral plasticity to emotional stimuli...
  5. pmc Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    Yanhua Ren
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Neurosci 29:14764-9. 2009
    ..The findings highlight the unique contributions of distinct cannabis constituents to addiction vulnerability and suggest that CBD may be a potential treatment for heroin craving and relapse...
  6. pmc Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression
    Andrej Nikoshkov
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:786-91. 2008
    ....
  7. ncbi request reprint Heroin abuse is characterized by discrete mesolimbic dopamine and opioid abnormalities and exaggerated nuclear receptor-related 1 transcriptional decline with age
    Monika Cs Horvath
    Department of Forensic Medicine, Semmelweis University, H 1085, Budapest, Hungary
    J Neurosci 27:13371-5. 2007
    ....
  8. pmc Mu opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers
    Katarina Drakenberg
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:7883-8. 2006
    ..Taken together, alterations in opioid neuropeptide systems might underlie enhanced opiate abuse vulnerability apparent in 118G individuals...
  9. ncbi request reprint Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor
    Florence Merg
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, Illkirch, France
    J Neurochem 97:292-301. 2006
    ..Collectively, the high potency and efficacy and the relative abundance suggest that Big Dyn may play a role in the KOR-mediated activation of G proteins...
  10. pmc Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor
    Paul Berghuis
    Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Scheeles väg 1 A1, Karolinska Institutet, S 17177 Stockholm, Sweden
    Proc Natl Acad Sci U S A 102:19115-20. 2005
    ..Moreover, eCBs use TrkB receptor-dependent signaling pathways to regulate subtype-selective interneuron migration and specification...

Research Grants28

  1. Dynorphin /kappa mesolimbic system in heroin abuse
    Yasmin Hurd; Fiscal Year: 2007
    ..By characterizing the DYN/kappa-related mesolimbic circuits in human heroin users, it might also be possible to develop even more effective therapeutic interventions for opiate abuse. ..
  2. Effects of Drug Abuse on Human Neurodevelopment
    Yasmin Hurd; Fiscal Year: 2007
    ..abstract_text> ..
  3. Neurodevelopmental Effects of Adolescent Cannabis Use
    Yasmin Hurd; Fiscal Year: 2007
    ..abstract_text> ..
  4. The Opioid mesolimbic system in heroin abuse
    Yasmin Hurd; Fiscal Year: 2009
    ..As such targeted for medications can be development. ..
  5. The neuronal basis of cannabis-induced developmental deficits in the CNS
    Yasmin L Hurd; Fiscal Year: 2010
    ..Such insights are of significant importance considering that marijuana is the most commonly used illicit drug by pregnant women and young women of childbearing age. ..
  6. MOLECULAR EFFECT OF DRUG ABUSE ON HUMAN NEURODEVELOPMENT
    Yasmin Hurd; Fiscal Year: 2001
    ....
  7. The Opioid mesolimbic system in heroin abuse
    Yasmin L Hurd; Fiscal Year: 2010
    ..As such targeted for medications can be development. ..