E Hollander

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. pmc Obsessive compulsive disorder comorbidity in DBA
    Stefano Pallanti
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Clin Pract Epidemiol Ment Health 4:6. 2008
  2. pmc Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly
    Joseph D Buxbaum
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, New York, USA
    BMC Med Genet 8:68. 2007
  3. ncbi request reprint Risperidone augmentation in treatment-resistant obsessive-compulsive disorder: a double-blind, placebo-controlled study
    Eric Hollander
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Int J Neuropsychopharmacol 6:397-401. 2003
  4. ncbi request reprint Targeted treatments for symptom domains in child and adolescent autism
    Eric Hollander
    Seaver and New York Autism Center of Excellence, Mount Sinai School of Medicine, New York, NY 10029, USA
    Lancet 362:732-4. 2003
  5. ncbi request reprint A double-blind, placebo-controlled study of the efficacy and safety of controlled-release fluvoxamine in patients with obsessive-compulsive disorder
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 64:640-7. 2003
  6. doi request reprint Should OCD leave the anxiety disorders in DSM-V? The case for obsessive compulsive-related disorders
    Eric Hollander
    Seaver and New York Autism Center of Excellence, Mount Sinai School of Medicine, New York, NY 10029, USA
    Depress Anxiety 25:317-29. 2008
  7. ncbi request reprint Divalproex in the treatment of impulsive aggression: efficacy in cluster B personality disorders
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychopharmacology 28:1186-97. 2003
  8. ncbi request reprint A double-blind, placebo-controlled trial of clonazepam in obsessive-compulsive disorder
    Eric Hollander
    Department, of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, USA
    World J Biol Psychiatry 4:30-4. 2003
  9. ncbi request reprint Obsessive-compulsive behaviors in parents of multiplex autism families
    Eric Hollander
    Department of Psychiatry and Seaver Autism Research Center, Box 1230, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Psychiatry Res 117:11-6. 2003
  10. ncbi request reprint Striatal volume on magnetic resonance imaging and repetitive behaviors in autism
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, Annenberg Bldg, 1 Gustave L Levy Place, New York, NY 10029, USA
    Biol Psychiatry 58:226-32. 2005

Detail Information

Publications105 found, 100 shown here

  1. pmc Obsessive compulsive disorder comorbidity in DBA
    Stefano Pallanti
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Clin Pract Epidemiol Ment Health 4:6. 2008
    ....
  2. pmc Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly
    Joseph D Buxbaum
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, New York, USA
    BMC Med Genet 8:68. 2007
    ..Sotos syndrome has been described in a number of patients with autism spectrum disorders, suggesting that NSD1 could be involved in other cases of autism and macrocephaly...
  3. ncbi request reprint Risperidone augmentation in treatment-resistant obsessive-compulsive disorder: a double-blind, placebo-controlled study
    Eric Hollander
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Int J Neuropsychopharmacol 6:397-401. 2003
    ..Risperidone may be an effective and well-tolerated augmentation strategy in treatment-resistant OCD subjects, but larger sample size studies are required to demonstrate this...
  4. ncbi request reprint Targeted treatments for symptom domains in child and adolescent autism
    Eric Hollander
    Seaver and New York Autism Center of Excellence, Mount Sinai School of Medicine, New York, NY 10029, USA
    Lancet 362:732-4. 2003
    ..Pharmacological treatments can effectively target problem behaviours associated with autism...
  5. ncbi request reprint A double-blind, placebo-controlled study of the efficacy and safety of controlled-release fluvoxamine in patients with obsessive-compulsive disorder
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 64:640-7. 2003
    ....
  6. doi request reprint Should OCD leave the anxiety disorders in DSM-V? The case for obsessive compulsive-related disorders
    Eric Hollander
    Seaver and New York Autism Center of Excellence, Mount Sinai School of Medicine, New York, NY 10029, USA
    Depress Anxiety 25:317-29. 2008
    ..There are both advantages and disadvantages in creating a new diagnostic category in DSM-V, and these are discussed in this article...
  7. ncbi request reprint Divalproex in the treatment of impulsive aggression: efficacy in cluster B personality disorders
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychopharmacology 28:1186-97. 2003
    ....
  8. ncbi request reprint A double-blind, placebo-controlled trial of clonazepam in obsessive-compulsive disorder
    Eric Hollander
    Department, of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, USA
    World J Biol Psychiatry 4:30-4. 2003
    ..Its effectiveness in specific subgroups of OCD patients with co-morbid anxiety disorders or as an augmentation strategy added to SSRIs remains to be determined...
  9. ncbi request reprint Obsessive-compulsive behaviors in parents of multiplex autism families
    Eric Hollander
    Department of Psychiatry and Seaver Autism Research Center, Box 1230, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Psychiatry Res 117:11-6. 2003
    ..Dichotomizing autistic probands by severity and type of repetitive behaviors (circumscribed interests and compulsive rituals) may yield more homogenous groups, which could be helpful in genetic linkage studies...
  10. ncbi request reprint Striatal volume on magnetic resonance imaging and repetitive behaviors in autism
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, Annenberg Bldg, 1 Gustave L Levy Place, New York, NY 10029, USA
    Biol Psychiatry 58:226-32. 2005
    ....
  11. ncbi request reprint A double-blind placebo-controlled pilot study of olanzapine in childhood/adolescent pervasive developmental disorder
    Eric Hollander
    Seaver and NY Autism Center of Excellence, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, New York 10029, USA
    J Child Adolesc Psychopharmacol 16:541-8. 2006
    ..Additional studies are needed to determine the efficacy and safety of olanzapine in the treatment of children with PDD...
  12. ncbi request reprint Oxytocin increases retention of social cognition in autism
    Eric Hollander
    Mount Sinai School of Medicine, New York, New York, USA
    Biol Psychiatry 61:498-503. 2007
    ..This study explored the effect of intravenous oxytocin administration on the retention of social information in autism...
  13. ncbi request reprint Pharmacological treatments of pathological gambling
    Eric Hollander
    Department of Psychiatry, Compulsive, Impulsive and Anxiety Disorders Program, Mount Sinai School of Medicine, Box 1230, One Gustave L Levy Place, New York, NY, USA
    J Gambl Stud 21:99-110. 2005
    ..This review focuses on recent research examining the treatment of pathological gambling and highlights methodological challenges for future studies...
  14. ncbi request reprint Impact of trait impulsivity and state aggression on divalproex versus placebo response in borderline personality disorder
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, 1 Gustave L Levy Place, Box 1230, New York, NY 10029 6574, USA
    Am J Psychiatry 162:621-4. 2005
    ....
  15. ncbi request reprint Divalproex sodium vs. placebo in the treatment of repetitive behaviours in autism spectrum disorder
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Int J Neuropsychopharmacol 9:209-13. 2006
    ..616). This study provides preliminary support for the use of divalproex in treating repetitive behaviours in ASD. Further research is needed to evaluate the specificity and mechanism of action of these findings...
  16. ncbi request reprint A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism
    Eric Hollander
    Seaver and New York Autism Center of Excellence, New York, NY 10029, USA
    Neuropsychopharmacology 30:582-9. 2005
    ..Limitations include small sample size and the crossover design of the study. Further replication and long-term maintenance trials are needed...
  17. ncbi request reprint Neurological soft signs as predictors of treatment response to selective serotonin reuptake inhibitors in obsessive-compulsive disorder
    Eric Hollander
    Mt Sinai School of Medicine, One Gustave Levy Place, Box 1230, NY, NY 10029, USA
    J Neuropsychiatry Clin Neurosci 17:472-7. 2005
    ..These subtle neurological abnormalities may implicate a potential subgroup of OCD patients with poorer treatment response. This may have treatment implications and therefore serve as a screening tool in OCD...
  18. ncbi request reprint Beyond refractory obsessions and anxiety states: toward remission
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 65:3-5. 2004
    ..These and other issues should be discussed at future meetings of the IOCDC and influence how we conceptualize the disorder and design future treatment trials...
  19. ncbi request reprint Impact of recent findings on study design of future autism clinical trials
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York City, New York 10029 6574, USA
    CNS Spectr 9:49-56. 2004
    ..The Internet System for Assessing Autistic Children system for managing multicenter clinical trials in autism and statistical issues in autism research are also described...
  20. ncbi request reprint Imaging monetary reward in pathological gamblers
    Eric Hollander
    Department of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    World J Biol Psychiatry 6:113-20. 2005
    ....
  21. ncbi request reprint Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger's disorders
    Eric Hollander
    Department of Psychiatry, Seaver Autism Research Center, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychopharmacology 28:193-8. 2003
    ..Repetitive behavior in autism spectrum disorders may be related to abnormalities in the oxytocin system, and may be partially ameliorated by synthetic oxytocin infusion...
  22. ncbi request reprint An open trial of divalproex sodium in autism spectrum disorders
    E Hollander
    Department of Psychiatry and Seaver Autism Research Center, Mt Sinai School of Medicine, New York, NY 10029 6574, USA
    J Clin Psychiatry 62:530-4. 2001
    ..Divalproex sodium is indicated as both an anticonvulsant in epilepsy and a mood stabilizer in bipolar illness and thus might be useful for these complicating symptoms in autism...
  23. ncbi request reprint Does sustained-release lithium reduce impulsive gambling and affective instability versus placebo in pathological gamblers with bipolar spectrum disorders?
    Eric Hollander
    Compulsive, Impulsive, and Anxiety Disorders Program, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Psychiatry 162:137-45. 2005
    ..To the authors' knowledge, this is the first placebo-controlled treatment study in pathological gamblers with bipolar spectrum disorders; it compares sustained-release lithium carbonate to placebo...
  24. ncbi request reprint A preliminary double-blind, placebo-controlled trial of divalproex sodium in borderline personality disorder
    E Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    J Clin Psychiatry 62:199-203. 2001
    ..Since anticonvulsant agents may be helpful in such symptomatology, we compared divalproex sodium with placebo in patients with borderline personality disorder...
  25. ncbi request reprint Venlafaxine in treatment-resistant obsessive-compulsive disorder
    Eric Hollander
    Department of Psychiatry, Compulsive, Impulsive, and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 64:546-50. 2003
    ..Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that might be effective in the treatment of OCD, even among those who have failed previous SSRI trials...
  26. ncbi request reprint Pharmacotherapy for obsessive-compulsive disorder
    E Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Psychiatr Clin North Am 23:643-56. 2000
    ..Augmentation and monotherapy have been explored with serotonergic enhancers, dopamine and 5-HT antagonists, enhancers of second-messenger systems, and GABAergic agents with varying efficacy...
  27. ncbi request reprint Refractory obsessive-compulsive disorder: state-of-the-art treatment
    Eric Hollander
    Department of Psychiatry, Compulsive, Impulsive, and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 63:20-9. 2002
    ..The authors synthesize state-of-the-art treatment and give practical advice for clinicians...
  28. doi request reprint FDG-PET study in pathological gamblers. 1. Lithium increases orbitofrontal, dorsolateral and cingulate metabolism
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 58:37-47. 2008
    ..Although mood stabilizers and serotonin reuptake inhibitors have shown some efficacy in the treatment of this condition, there is little known about how these pharmacological interventions work...
  29. ncbi request reprint Acute and long-term treatment and prevention of relapse of obsessive-compulsive disorder with paroxetine
    Eric Hollander
    Department of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6574, USA
    J Clin Psychiatry 64:1113-21. 2003
    ..This study evaluated the acute safety and efficacy and long-term efficacy, safety, and impact on relapse prevention of paroxetine in obsessive-compulsive disorder...
  30. ncbi request reprint Effect of fluoxetine on regional cerebral metabolism in autistic spectrum disorders: a pilot study
    M S Buchsbaum
    Neiroscience PET Laboratory, Mt Sinai School of Medicine, New York, NY 10029 6574, USA
    Int J Neuropsychopharmacol 4:119-25. 2001
    ..These results are consistent with those in depression indicating that higher cingulate gyrus metabolic rates at baseline predict SRI response...
  31. ncbi request reprint Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Am J Psychiatry 163:303-12. 2006
    ..The authors examined the efficacy and tolerability of the opioid antagonist nalmefene in the treatment of adults with pathological gambling...
  32. ncbi request reprint Limbic circuitry in patients with autism spectrum disorders studied with positron emission tomography and magnetic resonance imaging
    M M Haznedar
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Am J Psychiatry 157:1994-2001. 2000
    ....
  33. ncbi request reprint Short-term single-blind fluvoxamine treatment of pathological gambling
    E Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Psychiatry 155:1781-3. 1998
    ..The authors' goal was to assess the efficacy and tolerability of the selective serotonin reuptake inhibitor fluvoxamine in the treatment of pathological gambling...
  34. ncbi request reprint Feeling unreal: a PET study of depersonalization disorder
    D Simeon
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Psychiatry 157:1782-8. 2000
    ..The goal of this study was to assess brain glucose metabolism and its relationship to dissociation measures and clinical symptoms in DSM-IV depersonalization disorder...
  35. ncbi request reprint Venlafaxine in children, adolescents, and young adults with autism spectrum disorders: an open retrospective clinical report
    E Hollander
    Department of Psychiatry and the Seaver Autism Research Center, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Child Neurol 15:132-5. 2000
    ..Controlled treatment trials with venlafaxine are warranted in autism spectrum disorders...
  36. ncbi request reprint B lymphocyte antigen D8/17 and repetitive behaviors in autism
    E Hollander
    Department of Psychiatry and the Seaver Autism Research Center, Mt Sinai School of Medicine, New York, NY 10029 6574, USA
    Am J Psychiatry 156:317-20. 1999
    ..The authors examined the rate of D8/17 expression in children with autism and its correlation with severity of repetitive behaviors...
  37. ncbi request reprint Noradrenergic function in pathological gambling: blunted growth hormone response to clonidine
    S Pallanti
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    J Psychopharmacol 24:847-53. 2010
    ..This peripheral noradrenergic dysfunction could be consistent with attenuated cortico-frontal noradrenergic function as shown in positron emission tomography (PET) studies of PG...
  38. ncbi request reprint Escitalopram in the treatment of impulsive-compulsive internet usage disorder: an open-label trial followed by a double-blind discontinuation phase
    Bernardo Dell'Osso
    Department of Psychiatry, Compulsive and Impulsive Disorders Program, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 69:452-6. 2008
    ..To assess the safety and efficacy of escitalopram in IC-IUD, we conducted a 10-week, open-label trial followed by a 9-week, double-blind, placebo-controlled discontinuation phase...
  39. ncbi request reprint Comorbid social anxiety and body dysmorphic disorder: managing the complicated patient
    E Hollander
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 60:27-31. 1999
    ..Additionally, depression and suicide are frequent complications of BDD. Pharmacologic and nonpharmacologic treatments for the management of BDD with coexisting social anxiety are presented in this article...
  40. ncbi request reprint Neuroendocrine predictors of response to intravenous clomipramine therapy for refractory obsessive-compulsive disorder
    S J Mathew
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Depress Anxiety 14:199-208. 2001
    ..The limitations of IV CMI as a specific probe of serotonin function are discussed...
  41. ncbi request reprint Lithium and valproate treatment of pathological gambling: a randomized single-blind study
    Stefano Pallanti
    Mount Sinai School of Medicine, New York, NY, USA
    J Clin Psychiatry 63:559-64. 2002
    ..The aim of the present study was to evaluate the efficacy and safety of lithium and valproate in nonbipolar pathological gamblers...
  42. doi request reprint Basal Ganglia activity in pathological gambling: a fluorodeoxyglucose-positron emission tomography study
    Stefano Pallanti
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Neuropsychobiology 62:132-8. 2010
    ..We extended our studies to include functional alterations of the striatum and thalamus in a cohort of patients with PG before and after treatment with lithium...
  43. pmc Divalproex sodium vs placebo for the treatment of irritability in children and adolescents with autism spectrum disorders
    Eric Hollander
    Department of Psychiatry, Montefiore Medical Center University Hospital for Albert Einstein College of Medicine, Child Psychiatry Annex, Bronx, NY 10467 2490, USA
    Neuropsychopharmacology 35:990-8. 2010
    ..This study suggests the efficacy of divalproex for the treatment of irritability in children and adolescents with ASD. Larger sample follow-up studies are warranted...
  44. ncbi request reprint Clinical evidence and potential neurobiological underpinnings of unresolved symptoms of depression
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, TX 75235, USA
    J Clin Psychiatry 69:246-58. 2008
    ..This article reviews research on the current understanding and management of residual symptoms, i.e., subthreshold depressive symptoms present after recovery from a major depressive episode...
  45. ncbi request reprint Topiramate plus paroxetine in treatment-resistant obsessive-compulsive disorder
    Eric Hollander
    Department of Psychiatry, Compulsive, Impulsive and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, New York 10029, USA
    Int Clin Psychopharmacol 21:189-91. 2006
    ..Our case suggests that topiramate might be beneficial in augmentation with selective serotonin reuptake inhibitors in patients with treatment-resistant OCD, although further investigations are warranted to confirm our findings...
  46. ncbi request reprint Serotonin-norepinephrine reuptake inhibitors in the treatment of obsessive-compulsive disorder: A critical review
    Bernardo Dell'Osso
    Department of Psychiatry, Compulsive, Impulsive and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 67:600-10. 2006
    ....
  47. doi request reprint Low-frequency rTMS over right dorsolateral prefrontal cortex in the treatment of resistant depression: cognitive improvement is independent from clinical response, resting motor threshold is related to clinical response
    S Pallanti
    Department of Psychiatry, Mount Sinai School of Medicine, Bronx, New York, NY, USA
    Neuropsychobiology 65:227-35. 2012
    ..We investigated the clinical, cognitive and neurophysiologic effects of a 3 weeks' protocol of low-frequency rTMS applied over the right DLPFC in resistant depression...
  48. doi request reprint Oxytocin administration attenuates stress reactivity in borderline personality disorder: a pilot study
    D Simeon
    Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine and Beth Israel Medical Center, 317 East 17th Street, New York, NY, USA
    Psychoneuroendocrinology 36:1418-21. 2011
    ..013). Results suggest that oxytocin may have a beneficial impact on emotional regulation in BPD, which merits further investigation and could have important treatment implications...
  49. ncbi request reprint Body dysmorphic disorder
    A Allen
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Psychiatr Clin North Am 23:617-28. 2000
    ..Investigations in brain imaging and genetics are underway. Research in pharmacotherapy and CBT, individually and combined, is needed to refine, extend, and optimize treatment...
  50. pmc Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity
    J D Buxbaum
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, New York, NY, 10029, USA
    Am J Hum Genet 68:1514-20. 2001
    ....
  51. ncbi request reprint Reliability and validity of the pathological gambling adaptation of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS)
    Stefano Pallanti
    Mount Sinai School of Medicine, New York, NY 10029, USA
    J Gambl Stud 21:431-43. 2005
    ..PG-YBOCS thus appears to be a reliable and valid measure of pathological gambling severity, and can be regarded as an important tool for clinicians and researchers treating pathological gamblers...
  52. ncbi request reprint Lack of evidence for association of the serotonin transporter gene SLC6A4 with autism
    Nicolas Ramoz
    Laboratory of Molecular Neuropsychiatry, Department of Psychiatry, Seaver Autism Research Center, Mount Sinai School of Medicine, New York, New York 10029, USA
    Biol Psychiatry 60:186-91. 2006
    ..Specific variants of the 5-HTT gene, SLC6A4, especially the insertion-deletion 5-HTTLPR promoter locus, have been found to modulate its expression and transporter function...
  53. pmc Predicting response to opiate antagonists and placebo in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 200:521-7. 2008
    ..No studies have systematically examined predictors of medication treatment outcome in PG. Understanding clinical variables related to treatment outcome should help generate treatment algorithms for PG...
  54. ncbi request reprint Oxytocin and experimental therapeutics in autism spectrum disorders
    Jennifer A Bartz
    Mount Sinai School of Medicine, New York, NY, USA
    Prog Brain Res 170:451-62. 2008
    ..Finally, we conclude with a discussion of directions for future research...
  55. ncbi request reprint Nefazodone treatment of pathological gambling: a prospective open-label controlled trial
    Stefano Pallanti
    Department of Psychiatry, Mount Sinai School of Medicine, New York, N Y, USA
    J Clin Psychiatry 63:1034-9. 2002
    ....
  56. ncbi request reprint The impact of comorbidity on the management of pathological gambling
    Bernardo Dell'Osso
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 10:619-21. 2005
    ..The identification of specific subtypes among patients with pathological gambling may be relevant to the choice of pharmacologic treatment...
  57. ncbi request reprint WCA recommendations for the long-term treatment of generalized anxiety disorder
    Christer Allgulander
    Department of Psychiatry, Harvard University School of Medicine, Boston, Massachusetts, USA
    CNS Spectr 8:53-61. 2003
    ..Treatment gains after a 12-week course of CBT may be maintained for up to 1 year. Currently, no guidelines exist for the long-term treatment of GAD...
  58. ncbi request reprint Impulsivity
    E Hollander
    Department of Psychiatry and the Compulsive, Impulsive, and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    J Psychopharmacol 14:S39-44. 2000
    ....
  59. ncbi request reprint An open-label trial of divalproex extended-release in the treatment of borderline personality disorder
    Daphne Simeon
    Department of Psychiatry, The Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    CNS Spectr 12:439-43. 2007
    ..Divalproex extended-release (ER) is used widely in clinical practice, which leads to the question of its efficacy and tolerability in treating BPD...
  60. ncbi request reprint Psychopharmacologic interventions for repetitive behaviors in autism spectrum disorders
    Latha Soorya
    Department of Psychiatry, Seaver and New York Autism Center of Excellence, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, NY 10029, USA
    Child Adolesc Psychiatr Clin N Am 17:753-71, viii. 2008
    ..To date, data are mixed for interventions commonly prescribed in clinical practice and suggest several areas of investigation in advancing research on the medication management of repetitive behaviors...
  61. ncbi request reprint Experimental therapeutics for refractory obsessive-compulsive disorder: translational approaches and new somatic developments
    Heather A Berlin
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Mt Sinai J Med 75:174-203. 2008
    ....
  62. ncbi request reprint Impulsive-compulsive sexual behavior
    Thomas M Mick
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 11:944-55. 2006
    ..The data regarding this disorder and its overlap with chemical addiction is limited. If the two disorders are to be grouped together, further data are needed...
  63. ncbi request reprint An open-label trial of venlafaxine in body dysmorphic disorder
    Andrea Allen
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    CNS Spectr 13:138-44. 2008
    ..This open-label trial examines venlafaxine's efficacy in BDD and is the first known study of this serotonin-norepinephrine reuptake inhibitor in BDD...
  64. ncbi request reprint A review of pharmacologic treatments for obsessive-compulsive disorder
    Alicia Kaplan
    Department of Psychiatry, Mount Sinai Scjhool of Medicine, New York, New York 10029, USA
    Psychiatr Serv 54:1111-8. 2003
    ..In this article the authors review studies of pharmacologic treatments...
  65. ncbi request reprint Peritraumatic reactions associated with the World Trade Center disaster
    Daphne Simeon
    Psychiatry Box 1229, Mt Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Am J Psychiatry 160:1702-5. 2003
    ..The World Trade Center disaster was of unprecedented magnitude and impact in U.S. history. The authors conducted a pilot survey investigating these effects...
  66. pmc Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly
    Joseph D Buxbaum
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Am J Med Genet B Neuropsychiatr Genet 144:484-91. 2007
    ..Screening of PTEN mutations is warranted in patients with autism and pronounced macrocephaly, even in the absence of other features of PTEN-related tumor syndromes...
  67. ncbi request reprint Comprehensive treatment of three patients with comorbid OCPD and ADHD
    Stephen C Josephson
    Cornell University Medical School, New York, NY, USA
    CNS Spectr 12:338-42. 2007
    ..Significant symptom reduction was observed as a result of this combined intervention...
  68. ncbi request reprint Obsessive-compulsive disorder spectrum as a scientific "metaphor"
    Stefano Pallanti
    Strategic Center of Excellence of Psychiatry, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    CNS Spectr 13:6-15. 2008
    ..By increasing research in this field, the OCD spectrum may evolve from a fragmented level of conceptualization as a "metaphor" to one that is more comprehensive and structured...
  69. ncbi request reprint The neuroscience of affiliation: forging links between basic and clinical research on neuropeptides and social behavior
    Jennifer A Bartz
    Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, NY 10029, USA
    Horm Behav 50:518-28. 2006
    ..Finally, unresolved issues and directions for future research are discussed...
  70. ncbi request reprint Fronto-thalamo-striatal gray and white matter volumes and anisotropy of their connections in bipolar spectrum illnesses
    M Mehmet Haznedar
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    Biol Psychiatry 57:733-42. 2005
    ....
  71. ncbi request reprint Dissociation and posttraumatic stress 1 year after the World Trade Center disaster: follow-up of a longitudinal survey
    Daphne Simeon
    Mount Sinai School of Medicine, Department of Psychiatry, New York, NY 10029, USA
    J Clin Psychiatry 66:231-7. 2005
    ..We conducted a 1-year follow-up of an original mail survey of early reactions to the World Trade Center disaster...
  72. ncbi request reprint Bipolar disorder and comorbid attention deficit hyperactivity disorder. A distinct clinical phenotype? Clinical characteristics and temperamental traits
    Silvia Bernardi
    Department of Psychiatry, Mount Sinai School of Medicine, New York 10029, USA
    World J Biol Psychiatry 11:656-66. 2010
    ..We further hypothesize that maladaptive temperament will be associated with the severity of both illnesses...
  73. pmc Relationship between whole blood serotonin and repetitive behaviors in autism
    Alexander Kolevzon
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Psychiatry Res 175:274-6. 2010
    ..No significant associations were found between serotonin level and the primary behavioral outcome measures. However, a significant inverse relationship between serotonin level and self-injury was demonstrated...
  74. ncbi request reprint Is obsessive-compulsive disorder an anxiety disorder?
    Jennifer A Bartz
    Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, NY 10029, USA
    Prog Neuropsychopharmacol Biol Psychiatry 30:338-52. 2006
    ..The implications of removing OCD from the anxiety disorders category and moving it to an OC spectrum disorders category, as is being proposed for the DSM-V, is discussed...
  75. ncbi request reprint Selective serotonin reuptake inhibitors in autism: a review of efficacy and tolerability
    Alexander Kolevzon
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    J Clin Psychiatry 67:407-14. 2006
    ..This article reviews the available data on the efficacy and tolerability of SSRIs in individuals with autism spectrum disorders. Objectives for future research in this area will also be suggested...
  76. ncbi request reprint Symptom domains in autism and related conditions: evidence for familiality
    Jeremy M Silverman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    Am J Med Genet 114:64-73. 2002
    ..Making distinctions among families by the severity of these features may be useful for identifying more genetically homogeneous subgroups in studies targeted at genes for specific autism-related symptom domains...
  77. ncbi request reprint Positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients
    Monte S Buchsbaum
    Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 53:157-68. 2006
    ..Our results are consistent with a frontostriatal circuit change related to both dopaminergic and serotonergic systems and with the presence of psychopharmacological subtypes within OCD...
  78. pmc The Gambling Symptom Assessment Scale (G-SAS): a reliability and validity study
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Psychiatry Res 166:76-84. 2009
    ..The correlations between the G-SAS and the PG-YBOCS and Clinical Global Impression rating were excellent. Findings suggest that the G-SAS is reliable and valid in assessing changes in symptoms during a drug treatment study...
  79. ncbi request reprint Autism-related routines and rituals associated with a mitochondrial aspartate/glutamate carrier SLC25A12 polymorphism
    Jeremy M Silverman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    Am J Med Genet B Neuropsychiatr Genet 147:408-10. 2008
    ..No other significant differences were observed. The rs2056202 polymorphism may be associated with levels of routines and rituals in autism and related disorders...
  80. ncbi request reprint Volumetric analysis and three-dimensional glucose metabolic mapping of the striatum and thalamus in patients with autism spectrum disorders
    M Mehmet Haznedar
    Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1505, New York, NY 10029, USA
    Am J Psychiatry 163:1252-63. 2006
    ..The authors used imaging studies to map volumetric and metabolic differences within the entire dorsoventral extent of the striatum and thalamus...
  81. ncbi request reprint Diagnosis and treatment of body dysmorphic disorder in adolescents
    Sallie Jo Hadley
    Mount Sinai Medical Center, Department of Psychiatry, Box 1230, New York, NY 10029, USA
    Curr Psychiatry Rep 4:108-13. 2002
    ....
  82. pmc Epidemiologic and clinical updates on impulse control disorders: a critical review
    Bernardo Dell'Osso
    Compulsive, Impulsive and Anxiety Disorders Program, Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, NY 10029, USA
    Eur Arch Psychiatry Clin Neurosci 256:464-75. 2006
    ..Particular attention is paid to the relationship between ICDs and obsessive-compulsive disorder (OCD). Finally, current pharmacological options for treating ICDs are presented and discussed...
  83. ncbi request reprint Ondansetron augmentation in treatment-resistant obsessive-compulsive disorder: a preliminary, single-blind, prospective study
    Stefano Pallanti
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    CNS Drugs 23:1047-55. 2009
    ..Trial registration number (ClinicalTrials.gov): NCT00796497...
  84. ncbi request reprint Brain stimulation techniques in the treatment of obsessive-compulsive disorder: current and future directions
    Bernardo Dell'Osso
    Department of Psychiatry, Compulsive, Impulsive and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY 10029, USA
    CNS Spectr 10:966-79, 983. 2005
    ..Nevertheless, promising findings regarding efficacy, tolerability, and non-invasiveness and/or reversibility of these techniques have increased interest in investigating their use in treatment-resistant OCD...
  85. ncbi request reprint Levetiracetam versus placebo in childhood and adolescent autism: a double-blind placebo-controlled study
    Stacey Wasserman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Int Clin Psychopharmacol 21:363-7. 2006
    ..These findings suggest that levetiracetam does not improve behavioral disturbances of autism, but are limited by the small sample size and lack of stratification of the autistic sample at baseline...
  86. ncbi request reprint Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, N Y, USA
    Neuropsychobiology 49:115-25. 2004
    ..Patients failed to show these patterns. Autism patients have dysfunction in some but not all of the key brain regions subserving verbal memory performance, and other regions may be recruited for task performance...
  87. ncbi request reprint Relationship of personality to dissociation and childhood trauma in borderline personality disorder
    Daphne Simeon
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    CNS Spectr 8:755-62. 2003
    ..The purpose of this study was to investigate the relationship between dissociation and childhood trauma in BPD and to explore the relationships of dissociation and trauma to various personality features of BPD...
  88. ncbi request reprint A preliminary study of cortisol and norepinephrine reactivity to psychosocial stress in borderline personality disorder with high and low dissociation
    Daphne Simeon
    Department of Psychiatry, Mount Sinai School of Medicine, Psychiatry Box 1230, One Gustave L Levy Place, New York, NY 10029, USA
    Psychiatry Res 149:177-84. 2007
    ..In conclusion, despite its small sample size this pilot study suggests that dissociative symptomatology may be a marker of heightened biological vulnerability to stress in BPD, and merits further study...
  89. ncbi request reprint Linkage analysis for autism in a subset families with obsessive-compulsive behaviors: evidence for an autism susceptibility gene on chromosome 1 and further support for susceptibility genes on chromosome 6 and 19
    J D Buxbaum
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mol Psychiatry 9:144-50. 2004
    ..The data suggest that there is an autism susceptibility gene on chromosome 1 and provide further support for the presence of autism susceptibility genes on chromosomes 6 and 19...
  90. ncbi request reprint Dermatology and conditions related to obsessive-compulsive disorder
    D J Stein
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032
    J Am Acad Dermatol 26:237-42. 1992
    ..Many of these disorders, which include trichotillomania, neurotic excoriation, onychophagia, body dysmorphic disorder, and dermatitis artefacta may respond to specific therapeutic interventions...
  91. ncbi request reprint Diagnosis and treatment of obsessive-compulsive disorder and related disorders
    B Dell'Osso
    Department of Psychiatry, Compulsive, Impulsive and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, NY, USA
    Int J Clin Pract 61:98-104. 2007
    ....
  92. ncbi request reprint Hypothalamic-pituitary-adrenal axis dysregulation in depersonalization disorder
    D Simeon
    Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Neuropsychopharmacology 25:793-5. 2001
    ..The purpose of this preliminary study was to investigate HPA axis function in dissociation...
  93. ncbi request reprint Heat shock protein 90 antibodies in autism
    M Evers
    Department of Psychiatry, Seaver Autism Research Center, Mt Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Mol Psychiatry 7:S26-8. 2002
  94. ncbi request reprint A qualitative analysis of nonresponse: management of treatment-refractory obsessive-compulsive disorder
    Stefano Pallanti
    Department of Psychiatry, University of Florence, Italy
    J Clin Psychiatry 65:6-10. 2004
    ..More results are needed before the effectiveness of the nonpharmacologic treatments for OCD can be determined...
  95. ncbi request reprint WCA Recommendations for the long-term treatment of posttraumatic stress disorder
    Dan J Stein
    Medical Research Council Research Unit on Anxiety Disorder, University of Stellenbosch, Cape Town, Tygerberg, South Africa
    CNS Spectr 8:31-9. 2003
    ..Only SSRIs have been proven effective and safe in long-term randomized controlled trials. Current guidelines from the Expert Consensus Panel for PTSD recommend treatment of chronic PTSD for a minimum of 12-24 months...
  96. ncbi request reprint Practice guideline for the treatment of patients with obsessive-compulsive disorder
    Lorrin M Koran
    Am J Psychiatry 164:5-53. 2007
  97. ncbi request reprint WCA recommendations for the long-term treatment of social phobia
    Michael Van Ameringen
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada
    CNS Spectr 8:40-52. 2003
    ..In light of the chronicity and disability associated with social phobia, as well as the high relapse rate after short-term therapy, it is recommended that effective treatment be continued for at least 12 months...
  98. ncbi request reprint Divalproex versus placebo for the prevention of irritability associated with fluoxetine treatment in autism spectrum disorder
    Evdokia Anagnostou
    J Clin Psychopharmacol 26:444-6. 2006
  99. ncbi request reprint WCA recommendations for the long-term treatment of panic disorder
    Mark H Pollack
    Division of Psychiatry, Huddinge University Hospital, Stockholm, Sweden
    CNS Spectr 8:17-30. 2003
    ..Long-term efficacy and ease of use are important considerations in treatment selection, as maintenance treatment is recommended for at least 12-24 months, and in some cases, indefinitely...
  100. ncbi request reprint Social anxiety in outpatients with schizophrenia: a relevant cause of disability
    Stefano Pallanti
    Department of Neurological and Psychiatric Sciences, University of Florence, Italy
    Am J Psychiatry 161:53-8. 2004
    ....
  101. ncbi request reprint WCA recommendations for the long-term treatment of obsessive-compulsive disorder in adults
    John H Greist
    Healthcare Technology Systems, Inc, Madison, Wisconsin 53717, USA
    CNS Spectr 8:7-16. 2003
    ..Further, pharmacotherapy for a minimum of 1-2 years is recommended before very gradual withdrawal may be considered...

Research Grants11

  1. PHARMACOTHERAPY OF ADOLESCENT BODY DYSMORPHIC DISORDER
    Eric Hollander; Fiscal Year: 1999
    ..When untreated, adolescent-onset BDD appears to often interfere with the developmental tasks of adolescence, to persist, and to cause substantial morbidity through out the life span. ..
  2. FLUOXETINE IN PEDIATRIC BODY DYSMORPHIC DISORDER
    Eric Hollander; Fiscal Year: 2006
    ..Abstract Not Provided. ..
  3. Greater New York Autism Research Center of Excellence
    Joseph Buxbaum; Fiscal Year: 2007
    ..Core B: Clinical Core; Core C: Data Management and Statistics Core; Core D: Information Transfer Core. ..
  4. Training in Psychopharmacology and Outcomes Research
    Ronald Rieder; Fiscal Year: 2007
    ..Stipends are requested to support the entry of two fellows per year for the initial two years and then three fellows per year for up to three years of training. ..
  5. FLUOXETINE IN PEDIATRIC BODY DYSMORPHIC DISORDER
    Eric Hollander; Fiscal Year: 2005
    ..Abstract Not Provided. ..
  6. Divalproex Sodium/Placebo In Child/Adolesent Autism
    Eric Hollander; Fiscal Year: 2003
    ....
  7. PHARMACOTHERAPY OF ADOLESCENT BODY DYSMORPHIC DISORDER
    Eric Hollander; Fiscal Year: 2002
    ..When untreated, adolescent-onset BDD appears to often interfere with the developmental tasks of adolescence, to persist, and to cause substantial morbidity through out the life span. ..
  8. PHARMACOTHERAPY OF ADOLESCENT BODY DYSMORPHIC DISORDER
    Eric Hollander; Fiscal Year: 2001
    ..When untreated, adolescent-onset BDD appears to often interfere with the developmental tasks of adolescence, to persist, and to cause substantial morbidity through out the life span. ..
  9. PHARMACOTHERAPY OF ADOLESCENT BODY DYSMORPHIC DISORDER
    Eric Hollander; Fiscal Year: 2000
    ..When untreated, adolescent-onset BDD appears to often interfere with the developmental tasks of adolescence, to persist, and to cause substantial morbidity through out the life span. ..