M Mehmet Haznedar

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi request reprint Cingulate gyrus volume and metabolism in the schizophrenia spectrum
    M Mehmet Haznedar
    Department of Psychiatry, Mount Sinai School of Medicine, Neuroscience PET Laboratory, One Gustave L Levy Place, P O Box 1505, New York, NY 10029 6574, USA
    Schizophr Res 71:249-62. 2004
  2. ncbi request reprint Volumetric analysis and three-dimensional glucose metabolic mapping of the striatum and thalamus in patients with autism spectrum disorders
    M Mehmet Haznedar
    Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1505, New York, NY 10029, USA
    Am J Psychiatry 163:1252-63. 2006
  3. pmc Potentiated amygdala response to repeated emotional pictures in borderline personality disorder
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, USA
    Biol Psychiatry 72:448-56. 2012
  4. ncbi request reprint Relative glucose metabolic rate higher in white matter in patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Radiology and Neuroscience, Mount Sinai School of Medicine, Mount Sinai Medical Center, New York, NY 10029 6574, USA
    Am J Psychiatry 164:1072-81. 2007
  5. ncbi request reprint FDG-PET in never-previously medicated psychotic adolescents treated with olanzapine or haloperidol
    Monte S Buchsbaum
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 94:293-305. 2007
  6. pmc Anterior limb of the internal capsule in schizotypal personality disorder: fiber-tract counting, volume, and anisotropy
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Schizophr Res 141:119-27. 2012
  7. pmc Effects of sex and normal aging on regional brain activation during verbal memory performance
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
    Neurobiol Aging 31:826-38. 2010
  8. pmc Cortical gray and white matter volume in unmedicated schizotypal and schizophrenia patients
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Schizophr Res 101:111-23. 2008
  9. ncbi request reprint Metabolic thalamocortical correlations during a verbal learning task and their comparison with correlations among regional volumes
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Brain Res 1114:125-37. 2006
  10. pmc Age and diffusion tensor anisotropy in adolescent and adult patients with schizophrenia
    Jason S Schneiderman
    Department of Psychiatry, Mount Sinai School of Medicine, NY, USA
    Neuroimage 45:662-71. 2009

Research Grants

  1. Diffusion Tensor Imaging in Autism
    M Mehmet Haznedar; Fiscal Year: 2002
  2. Diffusion Tensor Imaging in Autism
    M Mehmet Haznedar; Fiscal Year: 2003
  3. Diffusion Tensor Imaging in Autism
    M Mehmet Haznedar; Fiscal Year: 2004

Detail Information

Publications29

  1. ncbi request reprint Cingulate gyrus volume and metabolism in the schizophrenia spectrum
    M Mehmet Haznedar
    Department of Psychiatry, Mount Sinai School of Medicine, Neuroscience PET Laboratory, One Gustave L Levy Place, P O Box 1505, New York, NY 10029 6574, USA
    Schizophr Res 71:249-62. 2004
    ....
  2. ncbi request reprint Volumetric analysis and three-dimensional glucose metabolic mapping of the striatum and thalamus in patients with autism spectrum disorders
    M Mehmet Haznedar
    Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1505, New York, NY 10029, USA
    Am J Psychiatry 163:1252-63. 2006
    ..The authors used imaging studies to map volumetric and metabolic differences within the entire dorsoventral extent of the striatum and thalamus...
  3. pmc Potentiated amygdala response to repeated emotional pictures in borderline personality disorder
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, USA
    Biol Psychiatry 72:448-56. 2012
    ..Borderline personality disorder (BPD) is characterized by an inability to regulate emotional responses. The amygdala is important in learning about the valence (goodness and badness) of stimuli and functions abnormally in BPD...
  4. ncbi request reprint Relative glucose metabolic rate higher in white matter in patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Radiology and Neuroscience, Mount Sinai School of Medicine, Mount Sinai Medical Center, New York, NY 10029 6574, USA
    Am J Psychiatry 164:1072-81. 2007
    ....
  5. ncbi request reprint FDG-PET in never-previously medicated psychotic adolescents treated with olanzapine or haloperidol
    Monte S Buchsbaum
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 94:293-305. 2007
    ..Haloperidol increased striatal metabolic rate more than olanzapine. Both drugs increased thalamic metabolic rates and this increase was significantly larger in younger (age 13-15) than older (16-21) patients...
  6. pmc Anterior limb of the internal capsule in schizotypal personality disorder: fiber-tract counting, volume, and anisotropy
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Schizophr Res 141:119-27. 2012
    ..In contrast to prior SZ studies that report lower FA, individuals with SPD show sparing. Our findings are consistent with a pattern of milder thalamo-frontal dysconnectivity in SPD than schizophrenia...
  7. pmc Effects of sex and normal aging on regional brain activation during verbal memory performance
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
    Neurobiol Aging 31:826-38. 2010
    ..These results suggest that both age-related metabolic decline and sex differences within frontal regions are more marked in medial frontal and cingulate areas, consistent with some age-related patterns of affective and cognitive change...
  8. pmc Cortical gray and white matter volume in unmedicated schizotypal and schizophrenia patients
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Schizophr Res 101:111-23. 2008
    ..Overall, our findings suggest that increased prefrontal volume in BA10 and sparing of volume loss in temporal cortex (BAs 22 and 20) may be a protective factor in SPD which reduces vulnerability to psychosis...
  9. ncbi request reprint Metabolic thalamocortical correlations during a verbal learning task and their comparison with correlations among regional volumes
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Brain Res 1114:125-37. 2006
    ....
  10. pmc Age and diffusion tensor anisotropy in adolescent and adult patients with schizophrenia
    Jason S Schneiderman
    Department of Psychiatry, Mount Sinai School of Medicine, NY, USA
    Neuroimage 45:662-71. 2009
    ..This suggests that tracts involved in the connectivity of the temporal lobe white matter deficits were already well in place in adolescent patients, while frontal lobe pathology continues to develop from adolescence to adulthood...
  11. pmc Smaller superior temporal gyrus volume specificity in schizotypal personality disorder
    Kim E Goldstein
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 112:14-23. 2009
    ..This is the first morphometric study to directly compare SPD and BPD patients in temporal lobe volume...
  12. pmc Diffusion tensor anisotropy in adolescents and adults
    Jason S Schneiderman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 55:96-111. 2007
    ..Sex differences were found in the majority of areas but were most marked in the cingulum bundle and internal capsule. These results suggest continuing white matter development between adolescence and adulthood...
  13. ncbi request reprint Amygdala-prefrontal disconnection in borderline personality disorder
    Antonia S New
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychopharmacology 32:1629-40. 2007
    ..We demonstrated no significant differences in amygdala volumes or metabolism between BPD patients and controls...
  14. doi request reprint Basal Ganglia activity in pathological gambling: a fluorodeoxyglucose-positron emission tomography study
    Stefano Pallanti
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Neuropsychobiology 62:132-8. 2010
    ..We extended our studies to include functional alterations of the striatum and thalamus in a cohort of patients with PG before and after treatment with lithium...
  15. pmc Larger putamen size in antipsychotic-naïve individuals with schizotypal personality disorder
    Eran Chemerinski
    Mount Sinai School of Medicine, Department of Psychiatry, New York, NY, United States
    Schizophr Res 143:158-64. 2013
    ....
  16. doi request reprint Diffusion tensor anisotropy in the cingulate gyrus in schizophrenia
    DEVORAH SEGAL
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroimage 50:357-65. 2010
    ..These results provide additional evidence for the presence of both white and gray matter abnormalities in the cingulate gyrus, which has been implicated in schizophrenia...
  17. pmc Frontal-striatal-thalamic mediodorsal nucleus dysfunction in schizophrenia-spectrum patients during sensorimotor gating
    Erin A Hazlett
    Department of Psychiatry, Box 1505, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroimage 42:1164-77. 2008
    ..Dysfunctional FST activation, particularly in the caudate may underlie PPI abnormalities in schizophrenia-spectrum patients...
  18. doi request reprint FDG-PET study in pathological gamblers. 1. Lithium increases orbitofrontal, dorsolateral and cingulate metabolism
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 58:37-47. 2008
    ..Although mood stabilizers and serotonin reuptake inhibitors have shown some efficacy in the treatment of this condition, there is little known about how these pharmacological interventions work...
  19. ncbi request reprint Internal capsule, corpus callosum and long associative fibers in good and poor outcome schizophrenia: a diffusion tensor imaging survey
    Serge A Mitelman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Schizophr Res 92:211-24. 2007
    ..We set out to confirm these exploratory findings and evaluate their relation to illness severity using a hypothesis-driven region-of-interest approach...
  20. pmc Anterior and posterior cingulate cortex volume in healthy adults: effects of aging and gender differences
    Sarah L Mann
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Brain Res 1401:18-29. 2011
    ..The Brodmann area-based approach also facilitates comparisons across studies that aim to draw inferences between age- and gender-related structural differences in the cingulate gyrus and corresponding differences in cingulate function...
  21. ncbi request reprint Deficient attentional modulation of startle eyeblink is associated with symptom severity in the schizophrenia spectrum
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, United States
    Schizophr Res 93:288-95. 2007
    ..Among the schizophrenia-spectrum sample, more deficient PPI during the attended prepulses was associated with greater symptom severity as measured by the total 18-item Brief Psychiatric Rating Scale score...
  22. ncbi request reprint White matter fractional anisotropy and outcome in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Schizophr Res 87:138-59. 2006
    ..We examined whether there is a relationship between white matter FA and outcome in patients with schizophrenia...
  23. ncbi request reprint Fronto-thalamo-striatal gray and white matter volumes and anisotropy of their connections in bipolar spectrum illnesses
    M Mehmet Haznedar
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    Biol Psychiatry 57:733-42. 2005
    ....
  24. pmc A comprehensive assessment of gray and white matter volumes and their relationship to outcome and severity in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience Positron Emission Tomography Laboratory, Box 1505, Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Neuroimage 37:449-62. 2007
    ..Poor outcome is associated with more posterior distribution (posteriorization) of both gray and white matter changes, and with preferential impairment in the unimodal visual and paralimbic cortical regions...
  25. ncbi request reprint Reduced anterior and posterior cingulate gray matter in borderline personality disorder
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, Box 1505, New York, NY 10029, USA
    Biol Psychiatry 58:614-23. 2005
    ..We extended this investigation by examining gray and white matter volume of frontal and cingulate gyrus Brodmann areas (BAs) in a large group of patients and healthy controls...
  26. pmc Correlations between ventricular enlargement and gray and white matter volumes of cortex, thalamus, striatum, and internal capsule in schizophrenia
    Guillermo Horga
    Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, NY 10029, USA
    Eur Arch Psychiatry Clin Neurosci 261:467-76. 2011
    ....
  27. ncbi request reprint Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, N Y, USA
    Neuropsychobiology 49:115-25. 2004
    ..Patients failed to show these patterns. Autism patients have dysfunction in some but not all of the key brain regions subserving verbal memory performance, and other regions may be recruited for task performance...
  28. ncbi request reprint Striatal volume on magnetic resonance imaging and repetitive behaviors in autism
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, Annenberg Bldg, 1 Gustave L Levy Place, New York, NY 10029, USA
    Biol Psychiatry 58:226-32. 2005
    ....
  29. ncbi request reprint Neuropsychological functioning in first-break, never-medicated adolescents with psychosis
    Adam M Brickman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Nerv Ment Dis 192:615-22. 2004
    ..The findings demonstrate neuropsychological deficits in adolescents with psychosis and suggest that cognitive deficits are core symptoms in psychotic disorders...

Research Grants3

  1. Diffusion Tensor Imaging in Autism
    M Mehmet Haznedar; Fiscal Year: 2002
    ..abstract_text> ..
  2. Diffusion Tensor Imaging in Autism
    M Mehmet Haznedar; Fiscal Year: 2003
    ..abstract_text> ..
  3. Diffusion Tensor Imaging in Autism
    M Mehmet Haznedar; Fiscal Year: 2004
    ..abstract_text> ..