Noam Harpaz

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. doi request reprint Precancerous lesions in inflammatory bowel disease
    Noam Harpaz
    Department of Pathology, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA
    Best Pract Res Clin Gastroenterol 27:257-67. 2013
  2. doi request reprint Colorectal dysplasia in chronic inflammatory bowel disease: pathology, clinical implications, and pathogenesis
    Noam Harpaz
    Department of Pathology, The Mount Sinai School of Medicine, New York, New York 10092, USA
    Arch Pathol Lab Med 134:876-95. 2010
  3. doi request reprint Progression to colorectal neoplasia in ulcerative colitis: effect of mesalamine
    Thomas Ullman
    Dr Henry D Janowitz Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Clin Gastroenterol Hepatol 6:1225-30; quiz 1177. 2008
  4. pmc A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans
    Gerold Bongers
    Immunology Institute, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    Gastroenterology 143:730-40. 2012
  5. doi request reprint Small bowel adenocarcinoma in Crohn's disease
    Maria Widmar
    Department of Surgery, Mount Sinai School of Medicine, One Gustave L Levy Pl, P O Box 1259, New York, NY 10029, USA
    J Gastrointest Surg 15:797-802. 2011
  6. doi request reprint Adenocarcinoma following ileal pouch-anal anastomosis for ulcerative colitis: review of 26 cases
    Bernardino C Branco
    Department of General Surgery, Mount Sinai School of Medicine, New York, New York 10029, USA
    Inflamm Bowel Dis 15:295-9. 2009
  7. doi request reprint Colorectal carcinoma in indeterminate colitis
    Bernardino C Branco
    Department of Surgery, Mount Sinai School of Medicine, New York, NY, USA
    Inflamm Bowel Dis 15:1076-81. 2009
  8. doi request reprint Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial
    James F Marion
    Mount Sinai School of Medicine, New York, New York 10028 0517, USA
    Am J Gastroenterol 103:2342-9. 2008
  9. doi request reprint Dysplasia is more common in the distal than proximal colon in ulcerative colitis surveillance
    Robert Goldstone
    Department of Medicine, Division of Gastroenterology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Inflamm Bowel Dis 18:832-7. 2012
  10. ncbi request reprint Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine
    Sierra Matula
    Dr Henry D Janowitz Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Clin Gastroenterol Hepatol 3:1015-21. 2005

Collaborators

Detail Information

Publications37

  1. doi request reprint Precancerous lesions in inflammatory bowel disease
    Noam Harpaz
    Department of Pathology, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA
    Best Pract Res Clin Gastroenterol 27:257-67. 2013
    ....
  2. doi request reprint Colorectal dysplasia in chronic inflammatory bowel disease: pathology, clinical implications, and pathogenesis
    Noam Harpaz
    Department of Pathology, The Mount Sinai School of Medicine, New York, New York 10092, USA
    Arch Pathol Lab Med 134:876-95. 2010
    ....
  3. doi request reprint Progression to colorectal neoplasia in ulcerative colitis: effect of mesalamine
    Thomas Ullman
    Dr Henry D Janowitz Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Clin Gastroenterol Hepatol 6:1225-30; quiz 1177. 2008
    ..The aim of this study was to compare rates of progression with advanced neoplasia in patient cohorts with UC taking low and high doses of mesalamine and to determine where in the process of neoplastic progression mesalamine might act...
  4. pmc A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans
    Gerold Bongers
    Immunology Institute, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    Gastroenterology 143:730-40. 2012
    ..Tumors that arise from these polyps frequently contain activating mutations in BRAF or KRAS, but little is known about the role of EGFR activation in their development...
  5. doi request reprint Small bowel adenocarcinoma in Crohn's disease
    Maria Widmar
    Department of Surgery, Mount Sinai School of Medicine, One Gustave L Levy Pl, P O Box 1259, New York, NY 10029, USA
    J Gastrointest Surg 15:797-802. 2011
    ..We present our recent experience with this entity in order to further elucidate its clinicopathological features and update our series from 1991...
  6. doi request reprint Adenocarcinoma following ileal pouch-anal anastomosis for ulcerative colitis: review of 26 cases
    Bernardino C Branco
    Department of General Surgery, Mount Sinai School of Medicine, New York, New York 10029, USA
    Inflamm Bowel Dis 15:295-9. 2009
    ....
  7. doi request reprint Colorectal carcinoma in indeterminate colitis
    Bernardino C Branco
    Department of Surgery, Mount Sinai School of Medicine, New York, NY, USA
    Inflamm Bowel Dis 15:1076-81. 2009
    ..We present our experience with 15 cases of IC-associated CRC in order to assess their clinicopathological features and to determine their survival rates...
  8. doi request reprint Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial
    James F Marion
    Mount Sinai School of Medicine, New York, New York 10028 0517, USA
    Am J Gastroenterol 103:2342-9. 2008
    ..We prospectively compared dye-spray technique using methylene blue to standard colonoscopic surveillance in detecting dysplasia...
  9. doi request reprint Dysplasia is more common in the distal than proximal colon in ulcerative colitis surveillance
    Robert Goldstone
    Department of Medicine, Division of Gastroenterology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Inflamm Bowel Dis 18:832-7. 2012
    ..The aim was to determine whether a difference exists in the anatomic distribution of dysplasia discovered in UC patients undergoing colonoscopic surveillance...
  10. ncbi request reprint Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine
    Sierra Matula
    Dr Henry D Janowitz Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Clin Gastroenterol Hepatol 3:1015-21. 2005
    ..Our aim was to determine the effect of the immunomodulators 6-mercaptopurine (6MP) and azathioprine (AZA) in preventing the development of dysplasia or CRC in UC...
  11. doi request reprint Farnesoid X receptor expression is decreased in colonic mucosa of patients with primary sclerosing cholangitis and colitis-associated neoplasia
    Joana Torres
    Dr Henry D Janowitz Division of Gastroenterology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Inflamm Bowel Dis 19:275-82. 2013
    ....
  12. ncbi request reprint Diagnosis and management of dysplasia in patients with inflammatory bowel diseases
    Steven H Itzkowitz
    The Dr Henry D Janowitz Division of Gastroenterology, Department of Medicine, The Mount Sinai School of Medicine, New York, New York 10029, USA
    Gastroenterology 126:1634-48. 2004
    ..The clinical application of newer molecular methods to detect neoplasia, particularly gene microarrays and stool DNA testing, also deserve further study...
  13. pmc Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors
    Masayuki Fukata
    Inflammatory Bowel Disease Center, Mount Sinai School of Medicine, New York, New York, USA
    Gastroenterology 133:1869-81. 2007
    ..The molecular mechanisms linking inflammation and colon carcinogenesis are incompletely understood. We tested the hypothesis that Toll-like receptor 4 (TLR4) is involved in tumorigenesis in the setting of chronic inflammation...
  14. doi request reprint Progression of low-grade dysplasia in ulcerative colitis: effect of colonic location
    Robert Goldstone
    The Dr Henry D Janowitz Division of Gastroenterology, The Mount Sinai School of Medicine, New York, New York 10029, USA
    Gastrointest Endosc 74:1087-93. 2011
    ..Emerging evidence suggests that the biology of sporadic colorectal neoplasia may differ between the proximal and distal colon. Whether such a difference exists in colitis-associated colorectal neoplasia is unknown...
  15. doi request reprint Appendiceal mucinous cystadenoma is a neoplastic complication of IBD: case-control study of primary appendiceal neoplasms
    Lurmag Orta
    Department of Pathology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Inflamm Bowel Dis 15:415-21. 2009
    ..IBD is a risk factor for development of colorectal neoplasia. Although IBD frequently involves the appendix microscopically, it is uncertain whether it also predisposes to appendiceal neoplasia...
  16. pmc Interpersonal influences on patients' surgical decision making: the role of close others
    Christine Rini
    Mount Sinai School of Medicine, New York, NY, USA
    J Behav Med 34:396-407. 2011
    ..Findings demonstrate the importance of considering social context when investigating patient decision making...
  17. doi request reprint Computer-assisted brush-biopsy analysis for the detection of dysplasia in a high-risk Barrett's esophagus surveillance population
    Sharmila Anandasabapathy
    Division of Gastroenterology, The Mount Sinai Medical Center, One Gustave Levy Place, New York, NY 10029, USA
    Dig Dis Sci 56:761-6. 2011
    ..Barrett's epithelial dysplasia, the direct precursor to esophageal adenocarcinoma, is often unapparent and frequently missed during surveillance of Barrett's esophagus with four-quadrant forceps biopsy protocol...
  18. pmc The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice
    Gerold Bongers
    Immunology Institute, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Clin Invest 120:3969-78. 2010
    ..Together, these results indicate that expression of US28 promotes development of intestinal dysplasia and cancer in transgenic mice and suggest that CMV infection may facilitate development of intestinal neoplasia in humans...
  19. ncbi request reprint Segmental colitis associated with diverticular disease and other IBD look-alikes
    Noam Harpaz
    Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Gastroenterol 40:S132-5. 2006
    ....
  20. pmc gC1qR expression in normal and pathologic human tissues: differential expression in tissues of epithelial and mesenchymal origin
    Francine R Dembitzer
    Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA
    J Histochem Cytochem 60:467-74. 2012
    ..The data suggest that increased gC1qR expression may be a marker of benign and pathologic cell proliferation, particularly in cells of epithelial origin, with potential diagnostic and therapeutic applications...
  21. doi request reprint Intramuscular corpora amylacea adjacent to ileal low-grade neuroendocrine tumours (typical carcinoids): a light microscopic, immunohistochemical and ultrastructural study
    Jaclyn Frances Hechtman
    Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Pathol 66:569-72. 2013
    ....
  22. doi request reprint High rates of metachronous colon cancer or dysplasia after segmental resection or subtotal colectomy in Crohn's colitis
    Elana A Maser
    The Henry D Janowitz Division of Gastroenterology, Department of Medicine, The Mount Sinai Hospital, New York, NY 10029, USA
    Inflamm Bowel Dis 19:1827-32. 2013
    ..It is unknown whether patients with Crohn's disease and colon cancer or dysplasia have a similar risk...
  23. ncbi request reprint Neoplastic precursor lesions related to the development of cancer in inflammatory bowel disease
    Noam Harpaz
    Division of Gastrointestinal Pathology, Department of Pathology, The Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Gastroenterol Clin North Am 36:901-26, vii-viii. 2007
    ..Technical enhancements to conventional endoscopy hold promise of improved efficiency and accuracy. Molecular-based testing may have a future role for risk stratification and early detection of neoplasia in inflammatory bowel disease...
  24. pmc High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease
    Joyce E Yu
    Division of Clinical Immunology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Clin Immunol 138:14-22. 2011
    ..Our results suggest that markedly elevated levels of antimicrobial antibodies in CGD do not correlate with a history of colitis but may reflect a specific defect in innate immunity in the face of chronic antigenic stimulation...
  25. pmc Tobacco, alcohol, and p53 overexpression in early colorectal neoplasia
    Mary Beth Terry
    Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    BMC Cancer 3:29. 2003
    ....
  26. doi request reprint Prognostic clinicopathologic factors in longitudinally followed patients with metastatic small bowel carcinoid tumors
    Thomas Curran
    Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA
    Pancreas 40:1253-7. 2011
    ..Neuroendocrine tumors demonstrate heterogeneous behavior based on the site of origin and histology. This study aimed to delineate prognostic clinicopathologic features in patients with metastatic midgut carcinoid...
  27. pmc Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease
    Shradha Agarwal
    Division of Clinical Immunology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Inflamm Bowel Dis 17:251-9. 2011
    ..This study examined whether defects in peripheral and/or intestinal lymphocytes are involved in disruption of the intestinal mucosa in CVID patients with inflammatory intestinal diseases...
  28. ncbi request reprint Intestinal low-grade tubuloglandular adenocarcinoma in inflammatory bowel disease
    Gabriel S Levi
    Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Surg Pathol 30:1022-9. 2006
    ..The potential of LGD to give rise directly to LGTGA, and by way of LGTGA to more aggressive cancers, reinforces recommendations in favor of aggressive management of IBD patients diagnosed with LGD...
  29. ncbi request reprint Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer
    Helen L Reeves
    Division of Liver Diseases, Mount Sinai School of Medicine, New York, NY 10029, USA
    Gastroenterology 126:1090-103. 2004
    ....
  30. ncbi request reprint Early and frequent histological recurrence of Crohn's disease in small intestinal allografts
    Noam Harpaz
    Department of Pathology, The Mount Sinai Medical Center, New York, NY 10029, USA
    Transplantation 80:1667-70. 2005
    ..However, systematic studies to determine the frequency, predictors, and clinical implications of recurrent Crohn's disease have not been reported..
  31. ncbi request reprint Bacterial-metal interactions: the potential role of aluminum and other trace elements in the etiology of Crohn's disease
    Daniel P Perl
    Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA
    Inflamm Bowel Dis 10:881-3. 2004
  32. ncbi request reprint Mucosal dysplasia in ileal pelvic pouches after restorative proctocolectomy
    Naris Nilubol
    Department of Surgery, The Mount Sinai Hospital, New York, New York, USA
    Dis Colon Rectum 50:825-31. 2007
    ..This study was designed to determine the prevalence of mucosal dysplasia in ileal pouch and any associated risk factors...
  33. ncbi request reprint Microcarcinoids in large intestinal adenomas
    Melissa Pulitzer
    Department of Pathology, Division of Gastrointestinal Pathology, The Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Surg Pathol 30:1531-6. 2006
    ....
  34. ncbi request reprint Segmentation of microscopic images of small intestinal glands with directional 2-D filters
    Hai Shan Wu
    Department of Pathology, Mount Sinai School of Medicine, New York, New York, USA
    Anal Quant Cytol Histol 27:291-300. 2005
    ..For comparisons, outputs of combined directional filters are shown along with those of the comparable nondirectional Gaussian filters. Segmentation results of small intestinal glands of both normal and cancer cases are provided...
  35. ncbi request reprint Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis
    Thomas Ullman
    Department of Medicine, The Dr Henry D Janowitz Division of Gastroenterology, Box 1069, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
    Gastroenterology 125:1311-9. 2003
    ....
  36. doi request reprint Is gastroduodenal biopsy safe in patients receiving aspirin and clopidogrel?: a prospective, randomized study involving 630 biopsies
    Matthew J Whitson
    Division of Gastroenterology, Department of Medicine, Mount Sinai Medical Center, New York, NY 10075, USA
    J Clin Gastroenterol 45:228-33. 2011
    ..To assess prospectively the bleeding risk attributable to gastroduodenal biopsy in subjects taking antiplatelet medications...
  37. doi request reprint Calcifying fibrous tumor of small intestine
    Patrick Emanuel
    Department of Pathology, The Mount Sinai School of Medicine, New York, NY 10029, USA
    Ann Diagn Pathol 12:138-41. 2008
    ....