James Gallo

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. pmc Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models
    Amit K Tiwari
    Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mol Cancer Ther 12:1343-55. 2013
  2. pmc Pharmacokinetic/ pharmacodynamic-driven drug development
    James M Gallo
    Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY, USA
    Mt Sinai J Med 77:381-8. 2010
  3. pmc Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models
    Zhan Wang
    Department of Pharmaceutical Sciences, Temple University, Philadelphia, Pennsylvania, USA
    Drug Metab Dispos 39:2155-61. 2011

Research Grants

Collaborators

  • Amit K Tiwari
  • Zhan Wang
  • Rong Zhang
  • Qingyu Zhou
  • Gary D Kruh

Detail Information

Publications3

  1. pmc Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models
    Amit K Tiwari
    Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mol Cancer Ther 12:1343-55. 2013
    ..As such it is relevant to examine how polymorphisms in these transporters influence topotecan activity in patients and whether coadministration of transport modulators could positively affect efficacy without increasing toxicity...
  2. pmc Pharmacokinetic/ pharmacodynamic-driven drug development
    James M Gallo
    Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY, USA
    Mt Sinai J Med 77:381-8. 2010
    ....
  3. pmc Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models
    Zhan Wang
    Department of Pharmaceutical Sciences, Temple University, Philadelphia, Pennsylvania, USA
    Drug Metab Dispos 39:2155-61. 2011
    ..The findings confirmed that both Abcc2 and Abcc3 significantly influenced the PK properties of MTX, and depending on the MTX dose and strain, alternate elimination pathways were elicited and saturable...

Research Grants14

  1. Cells Designed to Deliver Anticancer Drugs by Apoptosis
    James Gallo; Fiscal Year: 2003
    ..AIDD is a novel strategy that offers many mechanisms to selectively deliver anticancer drugs to tumors. ..
  2. Development of Targeted Anticancer Drugs
    James Gallo; Fiscal Year: 2009
    ....
  3. Development of Targeted Anticancer Drugs
    James Gallo; Fiscal Year: 2009
    ..It is believed that this approach offers the best opportunity to develop drugs in a rational and optimal manner. ..
  4. Development of Targeted Anticancer Drugs
    James M Gallo; Fiscal Year: 2010
    ....
  5. INTERACTIONS BETWEEN CYTOTOXIC AND ANTIANGIOGENIC DRUGS
    James Gallo; Fiscal Year: 2007
    ..abstract_text> ..
  6. Cells Designed to Deliver Anticancer Drugs by Apoptosis
    James Gallo; Fiscal Year: 2006
    ..AIDD is a novel strategy that offers many mechanisms to selectively deliver anticancer drugs to tumors. ..
  7. INTERACTIONS BETWEEN CYTOTOXIC AND ANTIANGIOGENIC DRUGS
    James M Gallo; Fiscal Year: 2011
    ..Quantitative pharmacological models will be derived and extrapolated to patients so that rational and effective multidrug therapy can be implemented in patients. ..