Research Topics
Genomes and GenesSpecies | Janine D FlorySummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
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Detail Information
Publications
Irritable assault and variation in the COMT geneJanine D Flory
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
Psychiatr Genet 17:344-6. 2007..These findings provide limited support for a role of COMT in modulating aggressive behavior, and are extended to people with personality disorders...- Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groupsMichael J Minzenberg
Bronx Veterans Affairs Medical Center, Bronx, New York, 14068, USA
Psychiatr Genet 16:117-24. 2006..We evaluated the relationship of the COMT genotype with diagnostic status and cognitive performance in schizotypal personality disorder... - Dispositional impulsivity in normal and abnormal samplesJanine D Flory
Department of Psychiatry, Box 1230, One Gustave Levy Place, Mount Sinai School of Medicine, New York, NY 10029, United States
J Psychiatr Res 40:438-47. 2006..Results from these analyses also lend support to a large body of work that demonstrates that normal and abnormal personality features are related... 
Alcohol dependence, disinhibited behavior and variation in the prodynorphin geneJanine D Flory
Department of Psychology, Queens College and The Graduate Center, City University of New York, New York, NY, USA
Biol Psychol 88:51-6. 2011..g., drug use, sexual activity)...- Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activityAhmad R Hariri
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Neurosci 26:13213-7. 2006..They also highlight a specific neurocognitive mechanism that may contribute to increased risk for addiction... - Perigenual anterior cingulate morphology covaries with perceived social standingPeter J Gianaros
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Soc Cogn Affect Neurosci 2:161-73. 2007..The pACC may represent a neuroanatomical substrate by which perceived social standing relates to mental and physical health... 
Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic functionMaria E Bleil
Department of Psychiatry, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94143 0848, USA
Psychosom Med 70:328-37. 2008..g., autonomic nervous system [ANS] dysfunction), the degree to which a general tendency to experience negative emotions may account for these relations is not known...- Neural basis of individual differences in impulsivity: contributions of corticolimbic circuits for behavioral arousal and controlSarah M Brown
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Emotion 6:239-45. 2006..Together, these findings suggest that dispositional impulsivity is influenced by the functional interplay of corticolimbic behavioral arousal and control circuits... - Self-reported sleep duration is associated with the metabolic syndrome in midlife adultsMartica H Hall
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Sleep 31:635-43. 2008..In the present study, we evaluated the relationship between sleep duration and presence of the metabolic syndrome, which is a cluster of physiologically interrelated risk factors for cardiometabolic disease... - Neurobiologic function and temperament in subjects with personality disordersVivian Mitropoulou
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
CNS Spectr 8:725-30. 2003.... - Joint Effect of Childhood Abuse and Family History of Major Depressive Disorder on Rates of PTSD in People with Personality DisordersJanine D Flory
Department of Psychiatry, Mount Sinai School of Medicine MSSM, One Gustave L Levy Place, NY 10029, USA
Depress Res Treat 2012:350461. 2012.... - COMT val158Met and executive control: a test of the benefit of specific deficits to translational researchAngus W MacDonald
Department of Psychology, University of Pittsburgh, USA
J Abnorm Psychol 116:306-12. 2007..These data suggest that the interpretability gained by including task manipulations to uncover specific deficits can enhance associations between cognitive and genetic levels of analysis... - Context processing in schizotypal personality disorder: evidence of specificity of impairment to the schizophrenia spectrumMargaret M McClure
VA VISN 3 Mental Illness Research, Education and Clinical Center, Bronx, New York 10468, USA
J Abnorm Psychol 117:342-54. 2008..These findings, which are quite similar to those previously reported in patients with schizophrenia, suggest that context processing deficits are specific to the schizophrenia spectrum and are not a reflection of overall psychopathology... - Serotonergic function in children with attention-deficit hyperactivity disorder: relationship to later antisocial personality disorderJanine D Flory
Department of Psychology, Queens College, City University of New York, 65 30 Kissena Boulevard, SB 318 Flushing, NY 11367, USA
Br J Psychiatry 190:410-4. 2007..Impulsive aggression in adulthood is associated with disturbances in serotonergic function. In contrast, research examining this association in childhood has yielded inconsistent results... - Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic functionSerina A Neumann
Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, 825 Fairfax Avenue, Norfolk, VA 23501
Biol Psychiatry 60:1155-62. 2006..Here, functional magnetic resonance imaging (fMRI) was used to examine the relation between a single nucleotide polymorphism (SNP) in CHT1 on regional brain reactivity relevant to autonomic (cholinergic) function... - The socio-economic status of communities predicts variation in brain serotonergic responsivityStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA 15260, USA
Psychol Med 35:519-28. 2005..Here we examine whether serotonergic responsivity covaries similarly with the SES of communities, as indexed by US Census data in the same study sample... - Socio-economic status covaries with central nervous system serotonergic responsivity as a function of allelic variation in the serotonin transporter gene-linked polymorphic regionStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, 506 EH, 4015 O Hara Street, Pittsburgh, PA 15260, USA
Psychoneuroendocrinology 29:651-68. 2004..We conclude that allelic variation at 5-HTTLPR moderates the influence of social position on CNS serotonergic responsivity... - Central nervous system serotonergic responsivity and aggressive disposition in menStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA, USA
Physiol Behav 77:705-9. 2002..This finding suggests that association of the MAO-A promoter polymorphism with this behavioral phenotype may be mediated, in part, by allele-specific variation in central serotonergic responsivity...