DAN FELSENFELD

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi Teaching resources. Regulation of complexes by cytoskeletal elements: integrins serve as force transducers linking mechanical stimuli and biochemical signals
    Dan P Felsenfeld
    Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Sci STKE 2005:tr27. 2005
  2. ncbi Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface
    Orlando D Gil
    Dept. of Pharmacology and Biological Chemistry, Box 1215, One Gustave L. Levy Place, Mt. Sinai School of Medicine, New York, NY 10029, USA
    J Cell Biol 162:719-30. 2003
  3. ncbi Interactions between the L1 cell adhesion molecule and ezrin support traction-force generation and can be regulated by tyrosine phosphorylation
    Takeshi Sakurai
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci Res 86:2602-14. 2008

Research Grants

  1. REGULATION OF NEURONAL MOTILITY
    DAN FELSENFELD; Fiscal Year: 2005

Collaborators

  • Takeshi Sakurai
  • Orlando D Gil
  • John D Whittard
  • Mihaela Gazdoiu
  • Stephen R Salton
  • Adam Waksman
  • Deanna L Benson
  • James Wu
  • Todd Joseph
  • Marc Y Fink
  • Melanie R Cassella
  • James A Kuo
  • Ann E Bradley

Detail Information

Publications3

  1. ncbi Teaching resources. Regulation of complexes by cytoskeletal elements: integrins serve as force transducers linking mechanical stimuli and biochemical signals
    Dan P Felsenfeld
    Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Sci STKE 2005:tr27. 2005
    ..quot; The lecture focuses on the capacity of integrins to serve as mechanotransducers, with particular emphasis on signaling mechanisms downstream of integrins...
  2. ncbi Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface
    Orlando D Gil
    Dept. of Pharmacology and Biological Chemistry, Box 1215, One Gustave L. Levy Place, Mt. Sinai School of Medicine, New York, NY 10029, USA
    J Cell Biol 162:719-30. 2003
    ..Moreover, inhibitors of L1CAM-ankyrin interactions promote L1CAM-mediated axon growth. Together, these results suggest that ankyrin binding plays a crucial role in the anti-coordinate regulation of L1CAM-mediated adhesion and migration...
  3. ncbi Interactions between the L1 cell adhesion molecule and ezrin support traction-force generation and can be regulated by tyrosine phosphorylation
    Takeshi Sakurai
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci Res 86:2602-14. 2008
    ..Collectively, these data suggest that L1-ezrin interactions mediated by the L1 juxtamembrane region are involved in traction-force generation and can be regulated by the phosphorylation of L1...

Research Grants5

  1. REGULATION OF NEURONAL MOTILITY
    DAN FELSENFELD; Fiscal Year: 2005
    ..Moreover, the information that we gain from studying adhesion receptors in neurons is likely to inform our understanding of cell migration in a variety of other systems, ranging from immune system function to tumor cell metastasis. ..