Jin Fan

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..Overall, the fMRI results suggest that the functional contrasts within this single task differentially activate three separable anatomical networks related to the components of attention...

..These data demonstrate that attention is not related to any single frequency band but that each network has a distinct oscillatory activity and time course...

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..A valid orienting cue enhances but an invalid cue diminishes the ability of executive control to overcome conflict. The results support the hypothesis of functional integration and interaction of these brain networks...

..These findings suggest that conflict processing is associated with the effective contribution of the RCZa to the neuronal activity of CCZ, as well as other cortical regions...

..The ANT can also serve as an endophenotype for genetic studies on attentional networks. This paper reviews our work with the ANT in studies of normal performance and various forms of psychopathology...

..These findings highlight the importance of investigating the implications of voluntary control via algorithms of mental operations...

..These results represent a first step in delineating the neurobiological basis of differential response to stimulant and nonstimulant medications for ADHD...

..The magnitude of the prefrontal and basal ganglia activation was positively correlated with severity of ADHD. Response competition alone did not yield group differences in activation...

..A review of the patterns of expression for ANKK1 and DRD2 and the extent of linkage disequilibrium between the two genes sheds light on additional criteria for the selection of candidate genes in imaging-genetic studies...

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..These results suggest that a functional mismatch between these two systems may represent one possible biological underpinning of SA risk, which is conferred by a parental history of addiction...

..A final experiment with forty 7-year-old children suggested that children like adults showed independence between the three networks under some conditions...

..These findings require replication and possible extension to other cognitive processes...

..This result suggests that the IPS plays an initiative role in this network in the processing of surprise targets, whereas ACC and DLPFC interact with each other to resolve conflict through attentional modulation implemented via the IPS...

..We tested the role that postsynaptic alpha(2A) adrenoceptors play in the activation of DLPFC evoked by warning cues using a placebo-controlled challenge with the alpha(2A) agonist guanfacine...

..g., trauma-exposed non-PTSD). In this project, we examined the neural mechanisms underlying differences in response to sexual violence, focusing specifically on the deliberate modification of emotional responses to negative stimuli...

..These results suggest that the basic neuropsychological constructs of the original go/no-go task were preserved in the emotional adaptation...

..In shaping our own imaging genetic hypotheses on the development of Attention Networks, we review relevant literature on core models of synaptic physiology and development in the anterior cingulate cortex...

..Our data suggest a clear functional dissociation between FI and ACC in which FI is more domain-specific than ACC when processing empathy for pain...

..Our findings have implications for a wide range of neuropsychiatric illnesses characterized by prominent deficits in higher-level social functioning...

..The results demonstrate how genetic differences among individuals can be linked to individual differences in neuromodulators and in the efficiency of the operation of an appropriate attentional network...

..These findings provide preliminary evidence that neural activity related to inhibitory control may differ as a function of DAT1 3'UTR genotype in youth with ADHD...

..We tested the hypothesis that BPD patients exhibit gross structural changes that parallel the respective increases in amygdala activation and impairment of rostral/subgenual ACC activation...

..g. attention) have been shown to be related to several anatomical networks. Recently, we have developed an Attention Network Test (ANT) that provides a separate measure for each of three anatomically defined attention networks...

..We argue that the dimensional overlap theory can be extended to serve as a viable unified theory that accounts for diverse attentional effects and their interactions and helps to elucidate neural networks subserving attentional control...

..Strategies that unify the wealth of biochemical knowledge pertaining to synapse formation with the functional measures of brain structure and activity may lead to new insights in developmental cognitive psychology...

..The present study used behavioral and functional neuroimaging techniques to examine inhibitory control processes in adolescents who had been diagnosed with ADHD during childhood...

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..These data strengthen the view that Stroop interference is neither robust nor inevitable and support the hypothesis that posthypnotic suggestion may exert a top-down influence on neural processing...

..The integration of cognitive, sensorimotor, and incentive signals in dACC places the region in an ideal position to select and prepare appropriate behavioral responses to achieve higher-level goals...

..We seek to use genetic information to help construct a multinode, multinetwork model that can explain, in part, individual differences in the development of attention over the course of development...

..To explore the possible role that functional abnormalities of the prefrontal cortex and basal ganglia play in the persistence of attention-deficit/hyperactivity disorder (ADHD) in adolescents aged 15 to 19 years...

..The neural substrates underlying processing of anger may also be altered. These changes may represent an expression of the volumetric and serotonergic deficits observed in these brain areas in BPD...

..The ANT may also serve as an activation task for neuroimaging studies and as a phenotype for the study of the influence of genes on attentional networks...

..These results may explain individual differences in hypnotizability and propose new ideas for studying the influence of suggestion on neural systems...

..Our findings illuminate how suggestion affects cognitive control by modulating activity in specific brain areas, including early visual modules, and provide a more scientific account relating the neural effects of suggestion to placebo...

..Here, we focus on age-related changes in inhibition and working memory...

..Although based on a small number of patients, our findings suggest that deficits of attention, especially the executive control of attention, may significantly contribute to the behavioral and cognitive deficits of aMCI...

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..Hippocampal activation showed no difference between source and item retrieval. This pattern of results supports a model proposing a larger role for the frontal lobes in encoding and retrieval of source information...

..Cognitive science has not fully exploited hypnosis and hypnotic suggestion as experimental tools. This study was designed to determine whether a hypnotic suggestion to hinder lexical processing could modulate the Stroop effect...

..One possible contributing factor to emotional instability is a failure to adequately employ adaptive cognitive regulatory strategies such as psychological distancing...

..However, few studies have directly investigated the cognitive domain in relation to alexithymia to examine whether alexithymic trait is related to less efficient voluntary control...

..Presently, we constrain our predictions for genetic association studies by focusing on the role of the anterior cingulate cortex (ACC) and of dopamine in the development of executive attention...

..These results suggest that cognitive and emotional processes at least partially share common brain networks and that AI might serve as a key node in a brain network subserving cognition-emotion integration...

..This study provides evidence of abnormalities in neurotransmission related to networks subserving executive control and alerting of attention, functions which have been previously implicated in ASD pathogenesis...

..Our findings provide evidence of an important role for the autonomic nervous system to the spontaneous activity of the brain during "rest."..

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..The general accuracy of the ADHD children was significantly lower than that of the normal controls. CONCLUSION: ADHD children may have impairments in their executive control network of attention...

..Our findings support this previous research by indicating that the major attentional deficit in schizophrenic patients is in a network that includes the anterior cingulate...

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..Here we briefly summarize work on the cognitive-affective neuroscience of attention-deficit/hyperactivity disorder...

..This model represents a plausible connectionist explanation for the functional structure and interaction of human attentional networks...

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..However, when compared to mother, the activation of MPFC disappeared in self-referential processing, which suggests that mother and self may have a common brain region in the MPFC and that the Chinese idea of self includes mother...