K L Davis

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi request reprint Neuropeptide abnormalities in patients with early Alzheimer disease
    K L Davis
    Department of Psychiatry, Mount Sinai School of Medicine, and Jewish Home and Hospital, New York, NY 10029, USA
    Arch Gen Psychiatry 56:981-7. 1999
  2. ncbi request reprint Symptoms, cognitive functioning, and adaptive skills in geriatric patients with lifelong schizophrenia: a comparison across treatment sites
    P D Harvey
    Department of Psychiatry, Mount Sinai School of Medicine and Franklin Delano Roosevelt Veterans Administration Medical Center, Montrose, NY 10029, USA
    Am J Psychiatry 155:1080-6. 1998
  3. ncbi request reprint Six-year follow-up study of cognitive and functional status across the lifespan in schizophrenia: a comparison with Alzheimer's disease and normal aging
    J I Friedman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Am J Psychiatry 158:1441-8. 2001
  4. ncbi request reprint Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease
    V Haroutunian
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Arch Neurol 55:1185-91. 1998
  5. ncbi request reprint Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease
    V Haroutunian
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Arch Neurol 56:713-8. 1999
  6. ncbi request reprint Convergence of cognitive and adaptive decline in late-life schizophrenia
    P D Harvey
    Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 35:77-84. 1999
  7. ncbi request reprint Aggression in elderly schizophrenia patients: a comparison of nursing home and state hospital residents
    C R Bowie
    Department of Psychology, Hofstra University, Hempsted, New York, USA
    J Neuropsychiatry Clin Neurosci 13:357-66. 2001
  8. ncbi request reprint Clinical, cognitive and functional characteristics of long-stay patients with schizophrenia: a comparison of VA and state hospital patients
    P D Harvey
    Department of Psychiatry, Mt Sinai School of Medicine, Box 1229, 10029, New York, NY, USA
    Schizophr Res 43:3-9. 2000
  9. ncbi request reprint Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline
    S Parvathy
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1230, New York, NY 10029, USA
    Arch Neurol 58:2025-32. 2001
  10. ncbi request reprint The convergence of neuropsychological testing and clinical ratings of cognitive impairment in patients with schizophrenia
    P D Harvey
    Mount Sinai School of Medicine, New York, NY 10029, USA
    Compr Psychiatry 42:306-13. 2001

Detail Information

Publications33

  1. ncbi request reprint Neuropeptide abnormalities in patients with early Alzheimer disease
    K L Davis
    Department of Psychiatry, Mount Sinai School of Medicine, and Jewish Home and Hospital, New York, NY 10029, USA
    Arch Gen Psychiatry 56:981-7. 1999
    ..To determine the relation between level of SLI and CRF-IR in different cerebrocortical regions to the earliest signs of cognitive deterioration in AD...
  2. ncbi request reprint Symptoms, cognitive functioning, and adaptive skills in geriatric patients with lifelong schizophrenia: a comparison across treatment sites
    P D Harvey
    Department of Psychiatry, Mount Sinai School of Medicine and Franklin Delano Roosevelt Veterans Administration Medical Center, Montrose, NY 10029, USA
    Am J Psychiatry 155:1080-6. 1998
    ....
  3. ncbi request reprint Six-year follow-up study of cognitive and functional status across the lifespan in schizophrenia: a comparison with Alzheimer's disease and normal aging
    J I Friedman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Am J Psychiatry 158:1441-8. 2001
    ..The rate of decline was compared to changes associated with Alzheimer's disease...
  4. ncbi request reprint Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease
    V Haroutunian
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Arch Neurol 55:1185-91. 1998
    ..Do the classical neuropathological lesions of AD precede, follow, or occur in synchrony with the earliest signs of cognitive deterioration?..
  5. ncbi request reprint Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease
    V Haroutunian
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    Arch Neurol 56:713-8. 1999
    ..Identification of the lesions that are most closely associated with the earliest symptoms of Alzheimer disease is crucial to the understanding of the disease process and the development of treatment strategies to affect its progression...
  6. ncbi request reprint Convergence of cognitive and adaptive decline in late-life schizophrenia
    P D Harvey
    Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 35:77-84. 1999
    ..These data indicate that cognitive decline may predict deterioration in overall functional status and imply that treatment of cognitive impairment might have a beneficial effect on global functional status...
  7. ncbi request reprint Aggression in elderly schizophrenia patients: a comparison of nursing home and state hospital residents
    C R Bowie
    Department of Psychology, Hofstra University, Hempsted, New York, USA
    J Neuropsychiatry Clin Neurosci 13:357-66. 2001
    ....
  8. ncbi request reprint Clinical, cognitive and functional characteristics of long-stay patients with schizophrenia: a comparison of VA and state hospital patients
    P D Harvey
    Department of Psychiatry, Mt Sinai School of Medicine, Box 1229, 10029, New York, NY, USA
    Schizophr Res 43:3-9. 2000
    ..These data indicate that VA patients may have reduced severity of functional and cognitive impairments relative to state hospital patients, but that the relationship between the different illness variables was similar in the two groups...
  9. ncbi request reprint Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline
    S Parvathy
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1230, New York, NY 10029, USA
    Arch Neurol 58:2025-32. 2001
    ....
  10. ncbi request reprint The convergence of neuropsychological testing and clinical ratings of cognitive impairment in patients with schizophrenia
    P D Harvey
    Mount Sinai School of Medicine, New York, NY 10029, USA
    Compr Psychiatry 42:306-13. 2001
    ..These results may also be specific to the clinical rating scale used, the Positive and Negative Syndrome Scale (PANSS)...
  11. ncbi request reprint Guanfacine treatment of cognitive impairment in schizophrenia
    J I Friedman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychopharmacology 25:402-9. 2001
    ....
  12. ncbi request reprint Has familial aggregation in Alzheimer's disease been overestimated?
    J M Silverman
    Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029, USA
    Int J Geriatr Psychiatry 15:631-7. 2000
    ..The relationship between onset age and familial aggregation suggests that no single estimate of the age-dependent risk (survival curve) is uniformly appropriate for relatives of AD probands...
  13. ncbi request reprint N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia
    S Dracheva
    Department of Psychiatry, Mount Sinai School of Medicine, Bronx Veterans Affairs Medical Center, NY 10468, USA
    Am J Psychiatry 158:1400-10. 2001
    ....
  14. ncbi request reprint Dopamine receptor transcript expression in striatum and prefrontal and occipital cortex. Focal abnormalities in orbitofrontal cortex in schizophrenia
    J H Meador-Woodruff
    Department of Psychiatry, University of Michigan, Ann Arbor, USA
    Arch Gen Psychiatry 54:1089-95. 1997
    ..We determined the expression of transcripts encoding the dopamine receptors in the brains of schizophrenic patients...
  15. ncbi request reprint Eye tracking, attention, and schizotypal symptoms in nonpsychotic relatives of patients with schizophrenia
    R S Keefe
    Department of Psychiatry, Mount Sinai School of Medicine, New York, USA
    Arch Gen Psychiatry 54:169-76. 1997
    ..We investigated whether these hypothesized components of a schizophrenia-related phenotype are associated with one another or are independent in nonpsychotic relatives of patients with schizophrenia...
  16. pmc Identifying families with likely genetic protective factors against Alzheimer disease
    J M Silverman
    Department of Psychiatry, Mt Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Am J Hum Genet 64:832-8. 1999
    ..Efforts to identify protective allele-bearing genes that are associated with very late-onset AD should target the families of nonagenarians and centenarians...
  17. ncbi request reprint The relationship between apolipoprotein E, dementia, and vascular illness
    D B Marin
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Atherosclerosis 140:173-80. 1998
    ..APOE epsilon4 is associated with dementias in the very old, whereas its relationship with either peripheral or central nervous system vascular disease without dementia is not as robust...
  18. ncbi request reprint The impact of behavioral impairment of functional ability in Alzheimer's disease
    C R Green
    Department of Psychiatry, Mount Sinai School of Medicine, New York, USA
    Int J Geriatr Psychiatry 14:307-16. 1999
    ..The latter can be achieved only by improving the progressive cognitive deficits of AD...
  19. ncbi request reprint Variations in differential gene expression patterns across multiple brain regions in schizophrenia
    P Katsel
    Department of Psychiatry, The Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6575, USA
    Schizophr Res 77:241-52. 2005
    ....
  20. ncbi request reprint Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease
    I Prohovnik
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Neurology 66:49-55. 2006
    ..Little is known about Alzheimer disease at advanced ages, although its incidence continues to increase at least through the ninth decade of life...
  21. ncbi request reprint CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy
    J I Friedman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Mol Psychiatry 13:261-6. 2008
    ..Our data thus confirm an association of CNTNAP2 to epilepsy outside the Old Order Amish population and suggest that dosage alteration of this gene may lead to a complex phenotype of schizophrenia, epilepsy and cognitive impairment...
  22. ncbi request reprint Restoration of cholinomimetic activity by clonidine in cholinergic plus noradrenergic lesioned rats
    V Haroutunian
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029
    Brain Res 507:261-6. 1990
    ..These results suggest that combined cholinergic/noradrenergic therapy may be of value in the treatment of some Alzheimer's disease patients...
  23. pmc Increased expression of receptor phosphotyrosine phosphatase-β/ζ is associated with molecular, cellular, behavioral and cognitive schizophrenia phenotypes
    N Takahashi
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Transl Psychiatry 1:e8. 2011
    ..Furthermore, our results implicate RPTPβ/ζ as a therapeutic target in schizophrenia...
  24. pmc Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity
    J D Buxbaum
    Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, New York, NY, 10029, USA
    Am J Hum Genet 68:1514-20. 2001
    ....
  25. pmc Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia
    C Schmauss
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029
    Proc Natl Acad Sci U S A 90:8942-6. 1993
    ..Many variables associated with either the course and/or the therapeutic management of the disease may account for the selective loss of D3 mRNA in the motor, somatosensory, and somatosensory association areas of schizophrenic brains...
  26. ncbi request reprint A comprehensive analysis of verbal fluency deficit in geriatric schizophrenia
    C R Bowie
    Department of Psychiatry, Mt Sinai School of Medicine, Box 1229, New York, NY 10029, USA
    Arch Clin Neuropsychol 19:289-303. 2004
    ..Verbal fluency impairment remains common and functionally relevant in schizophrenia patients in late life...
  27. ncbi request reprint Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene
    J D Buxbaum
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mol Psychiatry 13:162-72. 2008
    ..Furthermore, the data indicate a role for RPTPbeta in the modulation of ERBB4 signaling that may in turn provide further support for an important role of neuregulin/ERBB4 signaling in the molecular basis of schizophrenia...
  28. ncbi request reprint Vesicular glutamate transporter transcript expression in the thalamus in schizophrenia
    R E Smith
    Mental Health Research Institute and Department of Psychiatry, University of Michigan Medical School, 205 Zina Pitcher Place, Ann Arbor, MI 48109-0720, USA
    Neuroreport 12:2885-7. 2001
    ..These findings support the hypothesis of glutamatergic dysfunction in the thalamus in schizophrenia...
  29. ncbi request reprint Protein kinase C-epsilon is necessary for erythropoietin's up-regulation of c-myc and for factor-dependent DNA synthesis. Evidence for discrete signals for growth and differentiation
    Y Li
    Laboratory for Cellular and Molecular Biology, Division of Hematology and Oncology, New England Deaconess Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 271:27025-30. 1996
    ..The results are consistent with discrete intracellular signals regulating erythroid cell growth and differentiation...
  30. ncbi request reprint Patterns of cortical activity and memory performance in Alzheimer's disease
    J Schroder
    Section of Gerontopsychiatry, Department of Psychiatry, University of Heidelberg, Heidelberg, Germany
    Biol Psychiatry 49:426-36. 2001
    ..Factor analysis provides statistical methods for evaluating patterns of cerebral changes in regional glucose uptake...
  31. ncbi request reprint NSAID and Alzheimer's disease; possible answers and new questions
    K L Davis
    Mol Psychiatry 7:925-6. 2002
  32. pmc Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
    Y Hakak
    Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA
    Proc Natl Acad Sci U S A 98:4746-51. 2001
    ..Most notable was the differential expression of myelination-related genes suggesting a disruption in oligodendrocyte function in schizophrenia...