MONTE STUART BUCHSBAUM

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. pmc Correlations between Diffusion Tensor Imaging (DTI) and Magnetic Resonance Spectroscopy (1H MRS) in schizophrenic patients and normal controls
    Cheuk Y Tang
    Department of Radiology, Mount Sinai School of Medicine NY, NY 10029, USA
    BMC Psychiatry 7:25. 2007
  2. ncbi request reprint Effect of fluoxetine on regional cerebral metabolism in autistic spectrum disorders: a pilot study
    M S Buchsbaum
    Neiroscience PET Laboratory, Mt Sinai School of Medicine, New York, NY 10029 6574, USA
    Int J Neuropsychopharmacol 4:119-25. 2001
  3. ncbi request reprint D2/D3 dopamine receptor binding with [F-18]fallypride in thalamus and cortex of patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 85:232-44. 2006
  4. ncbi request reprint Positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients
    Monte S Buchsbaum
    Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 53:157-68. 2006
  5. ncbi request reprint Thalamocortical circuits: fMRI assessment of the pulvinar and medial dorsal nucleus in normal volunteers
    Monte S Buchsbaum
    Department of Psychiatry, Mount Sinai School of Medicine, Box 1505, New York, NY 10029 6574, USA
    Neurosci Lett 404:282-7. 2006
  6. ncbi request reprint Relative glucose metabolic rate higher in white matter in patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Radiology and Neuroscience, Mount Sinai School of Medicine, Mount Sinai Medical Center, New York, NY 10029 6574, USA
    Am J Psychiatry 164:1072-81. 2007
  7. ncbi request reprint Diffusion tensor imaging in schizophrenia
    Monte S Buchsbaum
    Neuroscience Positron Emission Tomography Laboratory, Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    Biol Psychiatry 60:1181-7. 2006
  8. ncbi request reprint Kraepelinian and non-Kraepelinian schizophrenia subgroup differences in cerebral metabolic rate
    Monte S Buchsbaum
    Neuroscience PET Laboratory and Department of Psychiatry, Mt Sinai School of Medicine, Box 1505, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Schizophr Res 55:25-40. 2002
  9. ncbi request reprint Caudate and putamen volumes in good and poor outcome patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Mount Sinai School of Medicine, Box 1505, 1 Gustave L Levy Place, New York, NY 10029 6574, USA
    Schizophr Res 64:53-62. 2003
  10. ncbi request reprint Differential metabolic rates in prefrontal and temporal Brodmann areas in schizophrenia and schizotypal personality disorder
    Monte S Buchsbaum
    Neuroscience PET Laboratory, Department of Psychiatry, Mt Sinai School of Medicine, Box 1505, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Schizophr Res 54:141-50. 2002

Research Grants

  1. PET Imaging of OFC and Amygdala in Panic Disorder
    Monte Buchsbaum; Fiscal Year: 2007

Collaborators

Detail Information

Publications65

  1. pmc Correlations between Diffusion Tensor Imaging (DTI) and Magnetic Resonance Spectroscopy (1H MRS) in schizophrenic patients and normal controls
    Cheuk Y Tang
    Department of Radiology, Mount Sinai School of Medicine NY, NY 10029, USA
    BMC Psychiatry 7:25. 2007
    ..DTI is thus sensitive to demyelination and other structural abnormalities. DTI has also shown abnormalities in these regions...
  2. ncbi request reprint Effect of fluoxetine on regional cerebral metabolism in autistic spectrum disorders: a pilot study
    M S Buchsbaum
    Neiroscience PET Laboratory, Mt Sinai School of Medicine, New York, NY 10029 6574, USA
    Int J Neuropsychopharmacol 4:119-25. 2001
    ..These results are consistent with those in depression indicating that higher cingulate gyrus metabolic rates at baseline predict SRI response...
  3. ncbi request reprint D2/D3 dopamine receptor binding with [F-18]fallypride in thalamus and cortex of patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 85:232-44. 2006
    ....
  4. ncbi request reprint Positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients
    Monte S Buchsbaum
    Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 53:157-68. 2006
    ..Our results are consistent with a frontostriatal circuit change related to both dopaminergic and serotonergic systems and with the presence of psychopharmacological subtypes within OCD...
  5. ncbi request reprint Thalamocortical circuits: fMRI assessment of the pulvinar and medial dorsal nucleus in normal volunteers
    Monte S Buchsbaum
    Department of Psychiatry, Mount Sinai School of Medicine, Box 1505, New York, NY 10029 6574, USA
    Neurosci Lett 404:282-7. 2006
    ..For the pulvinar, maximal functional connectivity was with parietal BA39; for anterior thalamus, with anterior cingulate...
  6. ncbi request reprint Relative glucose metabolic rate higher in white matter in patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Radiology and Neuroscience, Mount Sinai School of Medicine, Mount Sinai Medical Center, New York, NY 10029 6574, USA
    Am J Psychiatry 164:1072-81. 2007
    ....
  7. ncbi request reprint Diffusion tensor imaging in schizophrenia
    Monte S Buchsbaum
    Neuroscience Positron Emission Tomography Laboratory, Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    Biol Psychiatry 60:1181-7. 2006
    ..Alignment of white matter axons as inferred from diffusion tensor imaging has indicated changes in schizophrenia in frontal and frontotemporal white matter...
  8. ncbi request reprint Kraepelinian and non-Kraepelinian schizophrenia subgroup differences in cerebral metabolic rate
    Monte S Buchsbaum
    Neuroscience PET Laboratory and Department of Psychiatry, Mt Sinai School of Medicine, Box 1505, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Schizophr Res 55:25-40. 2002
    ..A combined frontal/temporal deficit or greater cortical change may be associated with poorer longitudinal course...
  9. ncbi request reprint Caudate and putamen volumes in good and poor outcome patients with schizophrenia
    Monte S Buchsbaum
    Department of Psychiatry, Mount Sinai School of Medicine, Box 1505, 1 Gustave L Levy Place, New York, NY 10029 6574, USA
    Schizophr Res 64:53-62. 2003
    ..This suggests the possibility that the expansion of putamen size may be a physiological correlate of neuroleptic responsiveness or that small putamen size at disease onset may be a predictor of outcome...
  10. ncbi request reprint Differential metabolic rates in prefrontal and temporal Brodmann areas in schizophrenia and schizotypal personality disorder
    Monte S Buchsbaum
    Neuroscience PET Laboratory, Department of Psychiatry, Mt Sinai School of Medicine, Box 1505, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Schizophr Res 54:141-50. 2002
    ..Metabolic rates in Brodmann area 10 were distinctly higher in SPD patients than in either normal volunteers or schizophrenic patients...
  11. ncbi request reprint Positron emission tomography with deoxyglucose-F18 imaging of sleep
    M S Buchsbaum
    Neuroscience PET Laboratory, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Neuropsychopharmacology 25:S50-6. 2001
    ..Compared with REM sleep, nonREM sleep was associated with significantly lower metabolic rates in the temporal and occipital regions, as well as the thalamus...
  12. ncbi request reprint Neuropsychological functioning in first-break, never-medicated adolescents with psychosis
    Adam M Brickman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Nerv Ment Dis 192:615-22. 2004
    ..The findings demonstrate neuropsychological deficits in adolescents with psychosis and suggest that cognitive deficits are core symptoms in psychotic disorders...
  13. doi request reprint FDG-PET and MRI imaging of the effects of sertindole and haloperidol in the prefrontal lobe in schizophrenia
    Monte S Buchsbaum
    University of California, San Diego, Department of Psychiatry, USA
    Schizophr Res 114:161-71. 2009
    ....
  14. ncbi request reprint FDG-PET in never-previously medicated psychotic adolescents treated with olanzapine or haloperidol
    Monte S Buchsbaum
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 94:293-305. 2007
    ..Haloperidol increased striatal metabolic rate more than olanzapine. Both drugs increased thalamic metabolic rates and this increase was significantly larger in younger (age 13-15) than older (16-21) patients...
  15. doi request reprint Statistical parametric mapping and cluster counting analysis of [18F] FDG-PET imaging in traumatic brain injury
    Jing Zhang
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    J Neurotrauma 27:35-49. 2010
    ....
  16. pmc Smaller superior temporal gyrus volume specificity in schizotypal personality disorder
    Kim E Goldstein
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 112:14-23. 2009
    ..This is the first morphometric study to directly compare SPD and BPD patients in temporal lobe volume...
  17. ncbi request reprint Postmortem assessment of thalamic nuclear volumes in subjects with schizophrenia
    William Byne
    Department of Psychiatry and Pathology, Mount Sinai School of Medicine, New York, USA
    Am J Psychiatry 159:59-65. 2002
    ..The authors assessed schizophrenia-associated changes in volume and neuronal number in the mediodorsal nucleus and the pulvinar regions of the thalamus...
  18. doi request reprint Basal Ganglia activity in pathological gambling: a fluorodeoxyglucose-positron emission tomography study
    Stefano Pallanti
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Neuropsychobiology 62:132-8. 2010
    ..We extended our studies to include functional alterations of the striatum and thalamus in a cohort of patients with PG before and after treatment with lithium...
  19. ncbi request reprint Magnetic resonance imaging of mediodorsal, pulvinar, and centromedian nuclei of the thalamus in patients with schizophrenia
    Eileen M Kemether
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Arch Gen Psychiatry 60:983-91. 2003
    ..The centromedian nucleus (CMN), important in attention and arousal, has not been previously studied with MRI...
  20. doi request reprint Changes in relative glucose metabolic rate following cortisol administration in aging veterans with posttraumatic stress disorder: an FDG-PET neuroimaging study
    Rachel Yehuda
    Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
    J Neuropsychiatry Clin Neurosci 21:132-43. 2009
    ..The restorative effects of HCORT on metabolism and working memory provide a rationale for examining the therapeutic benefits of glucocorticoid manipulation in aging PTSD patients...
  21. ncbi request reprint Deficient attentional modulation of startle eyeblink is associated with symptom severity in the schizophrenia spectrum
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, United States
    Schizophr Res 93:288-95. 2007
    ..Among the schizophrenia-spectrum sample, more deficient PPI during the attended prepulses was associated with greater symptom severity as measured by the total 18-item Brief Psychiatric Rating Scale score...
  22. ncbi request reprint Amygdala-prefrontal disconnection in borderline personality disorder
    Antonia S New
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychopharmacology 32:1629-40. 2007
    ..We demonstrated no significant differences in amygdala volumes or metabolism between BPD patients and controls...
  23. pmc The effect of doxapram on brain imaging in patients with panic disorder
    Amir Garakani
    Laboratory of Clinical Psychobiology, Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Eur Neuropsychopharmacol 17:672-86. 2007
    ..This suggests that panic disorder patients activate frontal inhibitory centers less than controls, a tendency that may lower the threshold for panic...
  24. ncbi request reprint Internal capsule, corpus callosum and long associative fibers in good and poor outcome schizophrenia: a diffusion tensor imaging survey
    Serge A Mitelman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Schizophr Res 92:211-24. 2007
    ..We set out to confirm these exploratory findings and evaluate their relation to illness severity using a hypothesis-driven region-of-interest approach...
  25. pmc Frontal-striatal-thalamic mediodorsal nucleus dysfunction in schizophrenia-spectrum patients during sensorimotor gating
    Erin A Hazlett
    Department of Psychiatry, Box 1505, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroimage 42:1164-77. 2008
    ..Dysfunctional FST activation, particularly in the caudate may underlie PPI abnormalities in schizophrenia-spectrum patients...
  26. doi request reprint Progressive ventricular expansion in chronic poor-outcome schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cogn Behav Neurol 23:85-8. 2010
    ..To compare progressive changes in lateral ventricular size in chronic schizophrenia patients with good and poor outcomes...
  27. pmc Very poor outcome schizophrenia: clinical and neuroimaging aspects
    Serge A Mitelman
    Medical Center, Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Int Rev Psychiatry 19:345-57. 2007
    ..These studies are summarized in detail in this review and future directions for neuroimaging assessment of very poor outcome patients with schizophrenia are suggested...
  28. pmc Cortical gray and white matter volume in unmedicated schizotypal and schizophrenia patients
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Schizophr Res 101:111-23. 2008
    ..Overall, our findings suggest that increased prefrontal volume in BA10 and sparing of volume loss in temporal cortex (BAs 22 and 20) may be a protective factor in SPD which reduces vulnerability to psychosis...
  29. doi request reprint The thalamus and schizophrenia: current status of research
    William Byne
    Department of Psychiatry, James J Peters VA Medical Center, Research Bldg Room 2F39, Bronx, NY 10468, USA
    Acta Neuropathol 117:347-68. 2009
    ..Evidence for anomalies of thalamic structure and function obtained from postmortem and neuroimaging studies is then examined and directions for further research proposed...
  30. doi request reprint FDG-PET study in pathological gamblers. 1. Lithium increases orbitofrontal, dorsolateral and cingulate metabolism
    Eric Hollander
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 58:37-47. 2008
    ..Although mood stabilizers and serotonin reuptake inhibitors have shown some efficacy in the treatment of this condition, there is little known about how these pharmacological interventions work...
  31. pmc Poor outcome in chronic schizophrenia is associated with progressive loss of volume of the putamen
    Serge A Mitelman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 113:241-5. 2009
    ..Present longitudinal study was designed to investigate progressive differences in striatal volumes among chronic schizophrenia patients with different outcomes and healthy subjects...
  32. pmc A longitudinal study of the corpus callosum in chronic schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    Schizophr Res 114:144-53. 2009
    ..Decreased callosal size and anisotropy have been described in schizophrenia patients but their longitudinal progression remains poorly understood...
  33. pmc Temporal characteristics of tract-specific anisotropy abnormalities in schizophrenia
    David M Carpenter
    Department of Radiology ISL, Box 1234, The Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Neuroreport 19:1369-72. 2008
    ..The findings suggest that there are white matter tract-specific degenerative mechanisms that may be present at the point of illness onset and may progress throughout the illness...
  34. ncbi request reprint Cingulate gyrus volume and metabolism in the schizophrenia spectrum
    M Mehmet Haznedar
    Department of Psychiatry, Mount Sinai School of Medicine, Neuroscience PET Laboratory, One Gustave L Levy Place, P O Box 1505, New York, NY 10029 6574, USA
    Schizophr Res 71:249-62. 2004
    ....
  35. ncbi request reprint Thalamus size and outcome in schizophrenia
    Adam M Brickman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Schizophr Res 71:473-84. 2004
    ..These findings are consistent with post-mortem and MRI measurement suggesting reduction in volume of the pulvinar, which occupies a large proportion of the ventral thalamus and which has prominent connections to the temporal lobe...
  36. ncbi request reprint Volume of the cingulate and outcome in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai School of Medicine, Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Schizophr Res 72:91-108. 2005
    ..We examined whether this pattern is seen within the anteroposterior arch of the cingulate gyrus...
  37. ncbi request reprint Response inhibition in adolescents diagnosed with attention deficit hyperactivity disorder during childhood: an event-related FMRI study
    Kurt P Schulz
    Department of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
    Am J Psychiatry 161:1650-7. 2004
    ..The present study used behavioral and functional neuroimaging techniques to examine inhibitory control processes in adolescents who had been diagnosed with ADHD during childhood...
  38. ncbi request reprint Fronto-thalamo-striatal gray and white matter volumes and anisotropy of their connections in bipolar spectrum illnesses
    M Mehmet Haznedar
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    Biol Psychiatry 57:733-42. 2005
    ....
  39. ncbi request reprint Correlations between MRI-assessed volumes of the thalamus and cortical Brodmann's areas in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Mount Sinai School of Medicine, New York, NY 10029, USA
    Schizophr Res 75:265-81. 2005
    ..We compared the thalamic-cortical volumetric correlational patterns in patients with schizophrenia and normal comparison subjects, and evaluated their relations to outcome...
  40. ncbi request reprint Cortical intercorrelations of temporal area volumes in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai Hospital, One Gustave L Levy Place, New York, NY 10029, USA
    Schizophr Res 76:207-29. 2005
    ....
  41. ncbi request reprint Cortical intercorrelations of frontal area volumes in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Neuroimage 27:753-70. 2005
    ..Abnormal regional volume intercorrelations between selected cortical areas in schizophrenia patients were previously reported in several MRI studies...
  42. ncbi request reprint Fluoxetine increases relative metabolic rate in prefrontal cortex in impulsive aggression
    Antonia S New
    Psychiatry Service Mount Sinai School of Medicine and the Bronx VA Medical Center, 130 West Kingsbridge Road, PO Box 1168, Bronx, NY 10468, USA
    Psychopharmacology (Berl) 176:451-8. 2004
    ..In addition, patients with impulsive aggression have an attenuation of symptoms with selective serotonin reuptake inhibitor (SSRI) treatment...
  43. ncbi request reprint Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, N Y, USA
    Neuropsychobiology 49:115-25. 2004
    ..Patients failed to show these patterns. Autism patients have dysfunction in some but not all of the key brain regions subserving verbal memory performance, and other regions may be recruited for task performance...
  44. ncbi request reprint Abnormal glucose metabolism in the mediodorsal nucleus of the thalamus in schizophrenia
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Psychiatry 161:305-14. 2004
    ....
  45. ncbi request reprint MRI assessment of gray and white matter distribution in Brodmann's areas of the cortex in patients with schizophrenia with good and poor outcomes
    Serge A Mitelman
    Department of Psychiatry, Box 1505, Mount Sinai Medical Center, One Gustave L Levy Pl, New York, NY 10029, USA
    Am J Psychiatry 160:2154-68. 2003
    ..High-resolution magnetic resonance imaging (MRI) was used to compare cortical gray and white matter and CSF volumes in schizophrenia patients with poor outcomes, schizophrenia patients with good outcomes, and healthy comparison subjects...
  46. ncbi request reprint Correlations between volumes of the pulvinar, centromedian, and mediodorsal nuclei and cortical Brodmann's areas in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Mount Sinai School of Medicine, Mount Sinai Medical Center, Box 1505, One Gustave L Levy Place, NY 10029, USA
    Neurosci Lett 392:16-21. 2006
    ....
  47. ncbi request reprint Volumetric analysis and three-dimensional glucose metabolic mapping of the striatum and thalamus in patients with autism spectrum disorders
    M Mehmet Haznedar
    Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1505, New York, NY 10029, USA
    Am J Psychiatry 163:1252-63. 2006
    ..The authors used imaging studies to map volumetric and metabolic differences within the entire dorsoventral extent of the striatum and thalamus...
  48. ncbi request reprint White matter fractional anisotropy and outcome in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Schizophr Res 87:138-59. 2006
    ..We examined whether there is a relationship between white matter FA and outcome in patients with schizophrenia...
  49. ncbi request reprint Metabolic disconnection between the mediodorsal nucleus of the thalamus and cortical Brodmann's areas of the left hemisphere in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Am J Psychiatry 162:1733-5. 2005
    ..The authors' goal was to examine interregional correlations of thalamocortical metabolic activity during a verbal learning task in schizophrenia...
  50. pmc Laboratory induced aggression: a positron emission tomography study of aggressive individuals with borderline personality disorder
    Antonia S New
    James J Peters Veterans Affairs Medical Center, Bronx, New York 10468, USA
    Biol Psychiatry 66:1107-14. 2009
    ..Preclinical studies show that orbital frontal cortex (OFC) plays a role in regulating impulsive aggression. Prior work has found OFC dysfunction in BPD...
  51. ncbi request reprint Deficient attentional modulation of the startle response in patients with schizotypal personality disorder
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, Box 1505, New York, NY 10029, USA
    Am J Psychiatry 160:1621-6. 2003
    ..The purpose of this study was to examine automatic sensorimotor gating and controlled attentional modulation of the startle eye blink response in unmedicated subjects with schizotypal personality disorder...
  52. ncbi request reprint Metabolic thalamocortical correlations during a verbal learning task and their comparison with correlations among regional volumes
    Serge A Mitelman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Brain Res 1114:125-37. 2006
    ....
  53. pmc Effects of sex and normal aging on regional brain activation during verbal memory performance
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
    Neurobiol Aging 31:826-38. 2010
    ..These results suggest that both age-related metabolic decline and sex differences within frontal regions are more marked in medial frontal and cingulate areas, consistent with some age-related patterns of affective and cognitive change...
  54. ncbi request reprint Reduced anterior and posterior cingulate gray matter in borderline personality disorder
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, Box 1505, New York, NY 10029, USA
    Biol Psychiatry 58:614-23. 2005
    ..We extended this investigation by examining gray and white matter volume of frontal and cingulate gyrus Brodmann areas (BAs) in a large group of patients and healthy controls...
  55. ncbi request reprint Internal capsule size in good-outcome and poor-outcome schizophrenia
    Adam M Brickman
    Taub Institute, P and S 16, Columbia University Medical Center, 630 West 168th St, New York, NY 10032, USA
    J Neuropsychiatry Clin Neurosci 18:364-76. 2006
    ..The findings suggest disruption of internal capsule fibers in poor-outcome patients with schizophrenia. These abnormalities may be independent of other structural changes in schizophrenia...
  56. ncbi request reprint Striatal size, glucose metabolic rate, and verbal learning in normal aging
    Adam M Brickman
    Department of Psychiatry, Neuroscience PET Laboratory, Box 1505, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Brain Res Cogn Brain Res 17:106-16. 2003
    ..Findings of significant involvement of striatal functioning in verbal learning are most likely accounted for by age and suggest an age-related shift from anterior to posterior circuitry in the human telencephalon...
  57. pmc Diffusion tensor anisotropy in adolescents and adults
    Jason S Schneiderman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuropsychobiology 55:96-111. 2007
    ..Sex differences were found in the majority of areas but were most marked in the cingulum bundle and internal capsule. These results suggest continuing white matter development between adolescence and adulthood...
  58. pmc A comprehensive assessment of gray and white matter volumes and their relationship to outcome and severity in schizophrenia
    Serge A Mitelman
    Department of Psychiatry, Neuroscience Positron Emission Tomography Laboratory, Box 1505, Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA
    Neuroimage 37:449-62. 2007
    ..Poor outcome is associated with more posterior distribution (posteriorization) of both gray and white matter changes, and with preferential impairment in the unimodal visual and paralimbic cortical regions...
  59. ncbi request reprint Imaging monetary reward in pathological gamblers
    Eric Hollander
    Department of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    World J Biol Psychiatry 6:113-20. 2005
    ....
  60. ncbi request reprint Schizophrenia-associated reduction of neuronal and oligodendrocyte numbers in the anterior principal thalamic nucleus
    William Byne
    Division of Basic and Laboratory Research, Bronx Veterans Affairs Medical Center, NY 10467, USA
    Schizophr Res 85:245-53. 2006
    ..These findings are consistent with a previous report of reduced neuronal number in the anterior principal nucleus of male SZs and add to a growing body of evidence implicating oligodendrocyte abnormalities in SZ...
  61. doi request reprint Diffusion tensor anisotropy in the cingulate gyrus in schizophrenia
    DEVORAH SEGAL
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroimage 50:357-65. 2010
    ..These results provide additional evidence for the presence of both white and gray matter abnormalities in the cingulate gyrus, which has been implicated in schizophrenia...
  62. pmc Age and diffusion tensor anisotropy in adolescent and adult patients with schizophrenia
    Jason S Schneiderman
    Department of Psychiatry, Mount Sinai School of Medicine, NY, USA
    Neuroimage 45:662-71. 2009
    ..This suggests that tracts involved in the connectivity of the temporal lobe white matter deficits were already well in place in adolescent patients, while frontal lobe pathology continues to develop from adolescence to adulthood...
  63. doi request reprint In vivo non-invasive serial monitoring of FDG-PET progression and regression in a rabbit model of atherosclerosis
    Stephen G Worthley
    Zena and Michael A Wiener Cardiovascular Institute, The Mount Sinai Medical Center, New York, NY 10029, USA
    Int J Cardiovasc Imaging 25:251-7. 2009
    ..67 +/- 0.02 to 0.53 +/- 0.02, P < 0.0001). FDG PET can quantify in vivo macrophage content and serially monitor changes in FDG activity in this rabbit model...
  64. ncbi request reprint Frontal cortex function
    Carol A Tamminga
    UT Southwestern Medical Center, Department of Psychiatry, 5323 Harry Hines Blvd, NC5 914, Dallas, TX 75390 9070, USA
    Am J Psychiatry 161:2178. 2004

Research Grants3

  1. PET Imaging of OFC and Amygdala in Panic Disorder
    Monte Buchsbaum; Fiscal Year: 2007
    ..The study aims to further understanding of the neuroanatomical substrate of panic attacks and to establish a possible mechanism of action for successful CBT. ..