Research Topics
| M S BuchsbaumSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
| Collaborators
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Detail Information
Publications
Regional cerebral blood flow during the Wisconsin Card Sort Test in schizotypal personality disorderM S Buchsbaum
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Schizophr Res 27:21-8. 1997..Thus, at least some SPD patients demonstrate abnormal patterns of prefrontal activation, perhaps as a compensation for dysfunction in other regions...
Ventricular volume and asymmetry in schizotypal personality disorder and schizophrenia assessed with magnetic resonance imagingM S Buchsbaum
Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029 6574, USA
Schizophr Res 27:45-53. 1997..The findings suggest that decreased left hemispheric volume, in frontal and temporal regions, may characterize both psychotic and non-psychotic disorders of the schizophrenia spectrum...
Functional brain imaging and aging in schizophreniaM S Buchsbaum
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Schizophr Res 27:129-41. 1997..Interpretation of imaging results is limited by the lack of studies in an adequate number of either first-break or older schizophrenic patients and the dearth of studies with longitudinal designs...
A method of basal forebrain anatomical standardization for functional image analysisM S Buchsbaum
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Psychiatry Res 84:113-25. 1998..3-1.6 mm. The validity of the method is confirmed by variance maps which reveal significant decreases in variance over spindle and bounding box alignment...
Three-dimensional analysis with MRI and PET of the size, shape, and function of the thalamus in the schizophrenia spectrumE A Hazlett
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Am J Psychiatry 156:1190-9. 1999....
Age-related shift in brain region activity during successful memory performanceE A Hazlett
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Neurobiol Aging 19:437-45. 1998..Age-related functional change may reflect dynamic re-allocation in a network of brain areas, not merely anatomically fixed neuronal loss or diminished capacity to perform...
Hypofrontality in unmedicated schizophrenia patients studied with PET during performance of a serial verbal learning taskE A Hazlett
Department of Psychiatry, Box 1505, Mount Sinai School of Medicine, 1 Gustave L Levy Place, 10029 6574, New York, NY, USA
Schizophr Res 43:33-46. 2000..Patients also exhibited hypofrontality (lower ratio of frontal to occipital rGMR) compared with normal subjects. Among the patients, more severe hypofrontality was associated with increased perseveration errors...
Feeling unreal: a PET study of depersonalization disorderD Simeon
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Am J Psychiatry 157:1782-8. 2000..The goal of this study was to assess brain glucose metabolism and its relationship to dissociation measures and clinical symptoms in DSM-IV depersonalization disorder...
Limbic circuitry in patients with autism spectrum disorders studied with positron emission tomography and magnetic resonance imagingM M Haznedar
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Am J Psychiatry 157:1994-2001. 2000....
Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patientsE A Hazlett
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Psychophysiology 35:186-98. 1998..Patients also had low metabolism in superior, middle, and inferior prefrontal cortex. Consistent with animal models, our results demonstrate the importance of the functional integrity of prefrontal cortex to PPI modulation...
Visual target detection paradigm for the study of selective attentionM H Tabert
Neuroscience PET Laboratory, Department of Psychiatry, Box 1505, The Mount Sinai Hospital, Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10029 6574, USA
Brain Res Brain Res Protoc 6:80-5. 2000....
Sensorimotor gating deficits and hypofrontality in schizophreniaE A Hazlett
Department of Psychiatry, Box 1505, Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10029, USA
Front Biosci 6:D1069-72. 2001..These findings extend animal models to humans by demonstrating the importance of frontal and occipital lobe coordination in the modulation of PPI...
Magnetic resonance imaging of the thalamic mediodorsal nucleus and pulvinar in schizophrenia and schizotypal personality disorderW Byne
Mount Sinai School of Medicine, New York, NY, USA
Arch Gen Psychiatry 58:133-40. 2001..Because frontal and temporal lobe volumes are diminished in schizophrenia, volume loss could characterize their primary thalamic relay nuclei (mediodorsal nucleus [MDN] and pulvinar)...
Positron emission tomography with deoxyglucose-F18 imaging of sleepM S Buchsbaum
Neuroscience PET Laboratory, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Neuropsychopharmacology 25:S50-6. 2001..Compared with REM sleep, nonREM sleep was associated with significantly lower metabolic rates in the temporal and occipital regions, as well as the thalamus...
Effect of fluoxetine on regional cerebral metabolism in autistic spectrum disorders: a pilot studyM S Buchsbaum
Neiroscience PET Laboratory, Mt Sinai School of Medicine, New York, NY 10029 6574, USA
Int J Neuropsychopharmacol 4:119-25. 2001..These results are consistent with those in depression indicating that higher cingulate gyrus metabolic rates at baseline predict SRI response...
Eeg alpha rhythm and glucose metabolic rate in the thalamus in schizophreniaP Danos
Neuroscience PET Laboratory, Mount Sinai Medical Center, New York, NY, USA
Neuropsychobiology 43:265-72. 2001..Furthermore, the present results suggest differences in thalamocortical circuits between normal controls and schizophrenic subjects...
Temporal lobe volume determined by magnetic resonance imaging in schizotypal personality disorder and schizophreniaJ E Downhill
Department of Psychiatry, Neuroscience PET Lab, Box 1505, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA
Schizophr Res 48:187-99. 2001....
Thalamic activation during an attention-to-prepulse startle modification paradigm: a functional MRI studyE A Hazlett
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
Biol Psychiatry 50:281-91. 2001..Further fMRI investigations may elucidate other key structures in the circuitry underlying normal and disordered modulation of PPI...
Regional and global changes in cerebral diffusion with normal agingA O Nusbaum
Department of Radiology, Mount Sinai School of Medicine, New York, NY, USA
AJNR Am J Neuroradiol 22:136-42. 2001..CONCLUSION: Quantitative diffusion histograms correlate with normal aging and may provide a global assessment of normal age-related changes and serve as a standard for comparison with neurodegenerative diseases...
Cerebral glucose metabolism in adults with early treated classic phenylketonuriaM P Wasserstein
Departments of Human Genetics and Pediatrics, New York, NY 10029, USA
Mol Genet Metab 87:272-7. 2006..The clinical significance of these abnormalities of glucose metabolism in specific areas of the brain remains unknown...
Localized and lateralized cerebral glucose metabolism associated with eye movements during REM sleep and wakefulness: a positron emission tomography (PET) studyC C Hong
Department of Psychiatry, University of California, San Diego, La Jolla 92093-0603, USA
Sleep 18:570-80. 1995..Our data also suggest right hemispheric specialization in saccadic eye movement control and reciprocal inhibition in the contralateral homologous area during higher cortical functioning...
Differential amygdala activation during emotional decision and recognition memory tasks using unpleasant words: an fMRI studyM H Tabert
Department of Neurology, Mount Sinai Medical Center, New York, NY, USA
Neuropsychologia 39:556-73. 2001..Finally, an increase in subject's state anxiety (evaluated by questionnaire) while in the scanner correlated with amygdala activation under some conditions...
The interstitial nuclei of the human anterior hypothalamus: an investigation of variation with sex, sexual orientation, and HIV statusW Byne
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
Horm Behav 40:86-92. 2001..Although there was a trend for INAH3 to occupy a smaller volume in homosexual men than in heterosexual men, there was no difference in the number of neurons within the nucleus based on sexual orientation...
Patterns of cortical activity and memory performance in Alzheimer's diseaseJ Schroder
Section of Gerontopsychiatry, Department of Psychiatry, University of Heidelberg, Heidelberg, Germany
Biol Psychiatry 49:426-36. 2001..Factor analysis provides statistical methods for evaluating patterns of cerebral changes in regional glucose uptake...
The effect of sleep deprivation on cerebral glucose metabolic rate in normal humans assessed with positron emission tomographyJ C Wu
University of California, Irvine
Sleep 14:155-62. 1991....
