DAVID BECHHOFERSummaryAffiliation: Mount Sinai School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Bacillus subtilis mRNA decay: new parts in the toolkitDavid H Bechhofer
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY, USA
Wiley Interdiscip Rev RNA 2:387-94. 2011..The presence of these ribonucleases in B. subtilis predicts significant differences from the well-established model of mRNA decay in Escherichia coli...
Decay of a model mRNA in Bacillus subtilis by a combination of RNase J1 5' exonuclease and RNase Y endonuclease activitiesShiyi Yao
Department of Pharmacology and Systems Therapeutics, Box 1603, Mount Sinai School of Medicine, New York, NY 10029, USA
J Bacteriol 193:6384-6. 2011..Evidence is presented that both of these activities determine the half-life of ΔermC mRNA...
Research Grants
- INITIATION OF MRNA DECAY IN BACILLUS SUBTILISDAVID BECHHOFER; Fiscal Year: 2009..Elucidating the mechanism of mRNA in this bacterium could lead to the design of new antibiotics that inhibit the mRNA decay process and thereby prevent successful bacterial colonization of human tissues. ..
- INITIATION OF MRNA DECAY IN BACILLUS SUBTILISDAVID BECHHOFER; Fiscal Year: 2009..Elucidating the mechanism of mRNA in this bacterium could lead to the design of new antibiotics that inhibit the mRNA decay process and thereby prevent successful bacterial colonization of human tissues. ..
- INITIATION OF MRNA DECAY IN BACILLUS SUBTILISDAVID BECHHOFER; Fiscal Year: 2007..Elucidating the mechanism of mRNA in this bacterium could lead to the design of new antibiotics that inhibit the mRNA decay process and thereby prevent successful bacterial colonization of human tissues. ..
- INITIATION OF MRNA DECAY IN BACILLUS SUBTILISDAVID BECHHOFER; Fiscal Year: 2005..The basis for control of Bs-R.Nase III activity in the cell will be investigated, providing the first look at ribonuclease gene regulation in B. subtilis. ..
- INITIATION OF MRNA DECAY IN BACILLUS SUBTILISDAVID BECHHOFER; Fiscal Year: 2000..Other endoribonuclease activities are likely to be present in B. Subtilis, and an in vitro system will be set up to detect such activities. ..
- INITIATION OF MRNA DECAY IN BACILLUS SUBTILISDavid H Bechhofer; Fiscal Year: 2010..Elucidating the mechanism of mRNA in this bacterium could lead to the design of new antibiotics that inhibit the mRNA decay process and thereby prevent successful bacterial colonization of human tissues. ..