Cristina Alberini

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. pmc Linking new information to a reactivated memory requires consolidation and not reconsolidation mechanisms
    Sophie Tronel
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    PLoS Biol 3:e293. 2005
  2. pmc Temporal requirement of C/EBPbeta in the amygdala following reactivation but not acquisition of inhibitory avoidance
    Maria H Milekic
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    Learn Mem 14:504-11. 2007
  3. pmc The role of protein synthesis during the labile phases of memory: revisiting the skepticism
    Cristina M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neurobiol Learn Mem 89:234-46. 2008
  4. pmc The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism
    Ozlem Bozdagi
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci 28:9857-69. 2008
  5. pmc The role of reconsolidation and the dynamic process of long-term memory formation and storage
    Cristina M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine New York, NY, USA
    Front Behav Neurosci 5:12. 2011
  6. pmc A critical role for IGF-II in memory consolidation and enhancement
    Dillon Y Chen
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    Nature 469:491-7. 2011
  7. pmc Persistent disruption of a traumatic memory by postretrieval inactivation of glucocorticoid receptors in the amygdala
    Sophie Tronel
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    Biol Psychiatry 62:33-9. 2007
  8. ncbi request reprint Mechanisms of memory stabilization and de-stabilization
    C M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine, Box 1065, New York, NY 10029, USA
    Cell Mol Life Sci 63:999-1008. 2006
  9. ncbi request reprint Mechanisms of memory stabilization: are consolidation and reconsolidation similar or distinct processes?
    Cristina M Alberini
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Trends Neurosci 28:51-6. 2005
  10. pmc Transcription factors in long-term memory and synaptic plasticity
    Cristina M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Physiol Rev 89:121-45. 2009

Research Grants

  1. Molecular bases of addictive memories
    Cristina Alberini; Fiscal Year: 2004
  2. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2002
  3. Mechanisms underlying memory stabilization
    Cristina M Alberini; Fiscal Year: 2010
  4. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2009
  5. Mechanisms underlying memory stabilization
    Cristina Alberini; Fiscal Year: 2009
  6. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2007
  7. Mechanisms underlying memory stabilization
    Cristina Alberini; Fiscal Year: 2007
  8. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2006
  9. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2005
  10. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2004

Collaborators

  • EMMANUEL LANDAU
  • Ana Garcia-Osta
  • Sophie Tronel
  • Stephen Maren
  • Matthew Shapiro
  • AVI MA'AYAN
  • GEORGE HUNTLEY
  • Robert D Blitzer
  • Antonia New
  • Ann E Kelley
  • Stephen M Taubenfeld
  • Maria H Milekic
  • Elizaveta V Muravieva
  • Gabriella Pollonini
  • Dillon Y Chen
  • Ozlem Bozdagi
  • Peter Serrano
  • Susana R Neves
  • Bernadette Saunier-Rebori
  • Dhananjay Bambah-Mukku
  • Sarah A Stern
  • Justin S Riceberg
  • John Hanna
  • Ravi Iyengar
  • Andre A Fenton
  • Eugenia L Friedman
  • Stephen R J Salton
  • Elizabeth A Grace
  • Anamika Sarkar
  • Panayiotis Tsokas
  • Kamara Patterson
  • Jana Kenney
  • James C Schaff
  • Jerry C P Yin
  • Jerry W Rudy
  • Todd C Sacktor
  • Erin Rich
  • Ion I Moraru
  • Padmini Rangamani
  • Masato Sadahiro
  • Joshua M Zimmerman
  • Sheena D Brown
  • Claudia Castellini
  • Jason Ruggiero
  • Kimberly A Stevens

Detail Information

Publications20

  1. pmc Linking new information to a reactivated memory requires consolidation and not reconsolidation mechanisms
    Sophie Tronel
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    PLoS Biol 3:e293. 2005
    ..Instead, it recruits mechanisms similar to those underlying consolidation of a new memory. Thus, linking new information to a reactivated memory is mediated by consolidation and not reconsolidation mechanisms...
  2. pmc Temporal requirement of C/EBPbeta in the amygdala following reactivation but not acquisition of inhibitory avoidance
    Maria H Milekic
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    Learn Mem 14:504-11. 2007
    ..Within these circuits, the C/EBPbeta-dependent molecular pathway appears to be differentially recruited...
  3. pmc The role of protein synthesis during the labile phases of memory: revisiting the skepticism
    Cristina M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neurobiol Learn Mem 89:234-46. 2008
    ....
  4. pmc The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism
    Ozlem Bozdagi
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci 28:9857-69. 2008
    ....
  5. pmc The role of reconsolidation and the dynamic process of long-term memory formation and storage
    Cristina M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine New York, NY, USA
    Front Behav Neurosci 5:12. 2011
    ..I also discuss the literature and results regarding the influence of the passage of time on the reconsolidation of memory. These points have important implications for the use of reconsolidation in therapeutic settings...
  6. pmc A critical role for IGF-II in memory consolidation and enhancement
    Dillon Y Chen
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    Nature 469:491-7. 2011
    ..In hippocampal slices, IGF-II promotes IGF-II receptor-dependent, persistent long-term potentiation after weak synaptic stimulation. Thus, IGF-II may represent a novel target for cognitive enhancement therapies...
  7. pmc Persistent disruption of a traumatic memory by postretrieval inactivation of glucocorticoid receptors in the amygdala
    Sophie Tronel
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    Biol Psychiatry 62:33-9. 2007
    ..Traumatic memories based on fear conditioning can be disrupted if interfering events or pharmacological interventions are applied following their retrieval...
  8. ncbi request reprint Mechanisms of memory stabilization and de-stabilization
    C M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine, Box 1065, New York, NY 10029, USA
    Cell Mol Life Sci 63:999-1008. 2006
    ..Here we discuss some of the questions currently debated in the field of memory consolidation and reconsolidation, the molecular and anatomical requirements for both processes and, finally, their functional relationship...
  9. ncbi request reprint Mechanisms of memory stabilization: are consolidation and reconsolidation similar or distinct processes?
    Cristina M Alberini
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Trends Neurosci 28:51-6. 2005
    ..This review concludes with a working model that could explain the apparent controversy of memory vulnerability after reactivation...
  10. pmc Transcription factors in long-term memory and synaptic plasticity
    Cristina M Alberini
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Physiol Rev 89:121-45. 2009
    ..The results of this work suggest that patterns of transcription regulation represent the molecular signatures of long-term synaptic changes and memory formation...
  11. ncbi request reprint Persistent disruption of an established morphine conditioned place preference
    Maria H Milekic
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci 26:3010-20. 2006
    ..Thus, established memories induced by a drug of abuse can be persistently disrupted after reactivation of the conditioning experience...
  12. ncbi request reprint Temporally graded requirement for protein synthesis following memory reactivation
    Maria H Milekic
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuron 36:521-5. 2002
    ..Here, we show that the requirement for protein synthesis of a reactivated memory is evident only when the memory is recent. In fact, memory vulnerability decreases as the time between the original training and the recall increases...
  13. pmc PKMzeta maintains spatial, instrumental, and classically conditioned long-term memories
    Peter Serrano
    Department of Physiology and Pharmacology, The Robert F Furchgott Center for Neural and Behavioral Science, State University of New York, Brooklyn, New York, USA
    PLoS Biol 6:2698-706. 2008
    ....
  14. ncbi request reprint MuSK expressed in the brain mediates cholinergic responses, synaptic plasticity, and memory formation
    Ana Garcia-Osta
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci 26:7919-32. 2006
    ..We conclude that MuSK plays an important role in brain functions, including memory formation. Therefore, its expression and role are broader than what was believed previously...
  15. pmc Disrupting the memory of places induced by drugs of abuse weakens motivational withdrawal in a context-dependent manner
    Stephen M Taubenfeld
    Departments of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Proc Natl Acad Sci U S A 107:12345-50. 2010
    ..Hence, targeting memories induced by drugs may represent an important strategy for attenuating context-conditioned withdrawal and therefore subsequent relapse in opiate addicts...
  16. pmc Preclinical assessment for selectively disrupting a traumatic memory via postretrieval inhibition of glucocorticoid receptors
    Stephen M Taubenfeld
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA
    Biol Psychiatry 65:249-57. 2009
    ..Here we tested parameters important for designing novel clinical protocols targeting the reconsolidation of a traumatic memory with RU38486...
  17. pmc Limited efficacy of propranolol on the reconsolidation of fear memories
    Elizaveta V Muravieva
    Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA
    Learn Mem 17:306-13. 2010
    ..The results indicate that the efficacy of systemic administration of propranolol in disrupting the reconsolidation of fear memories is limited...
  18. pmc Amyloid beta mediates memory formation
    Ana Garcia-Osta
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Learn Mem 16:267-72. 2009
    ..Correlative data suggest that Abeta peptides may exert their function via nicotinic acethylcoline receptors. Hence, Abeta peptides, including Abeta(1-42), play an important physiological role in hippocampal memory formation...
  19. pmc Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks
    Susana R Neves
    Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1215, New York, NY 10029, USA
    Cell 133:666-80. 2008
    ....
  20. ncbi request reprint Profound molecular changes following hippocampal slice preparation: loss of AMPA receptor subunits and uncoupled mRNA/protein expression
    Stephen M Taubenfeld
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurochem 81:1348-60. 2002
    ..These data reveal that significant discrepancies exist between the slice preparation and the intact hippocampus in terms of the metabolism of molecular components known to be involved in synaptic plasticity...

Research Grants14

  1. Molecular bases of addictive memories
    Cristina Alberini; Fiscal Year: 2004
    ..2) To determine the behavioral specificity of the requirement for protein synthesis in addiction. 3) To determine whether the requirement for protein synthesis is a general mechanism underlying addictive memories. ..
  2. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2002
    ..An understanding of the molecular changes underlying memory formation may indicate new strategies for the treatment of memory disorders. ..
  3. Mechanisms underlying memory stabilization
    Cristina M Alberini; Fiscal Year: 2010
    ..e. PTSD, phobias, addiction and depression) and debilitating conditions of memory loss such as those occurring in aging and Alzheimer's Disease. ..
  4. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2009
    ....
  5. Mechanisms underlying memory stabilization
    Cristina Alberini; Fiscal Year: 2009
    ..e. PTSD, phobias, addiction and depression) and debilitating conditions of memory loss such as those occurring in aging and Alzheimer's Disease. ..
  6. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2007
    ....
  7. Mechanisms underlying memory stabilization
    Cristina Alberini; Fiscal Year: 2007
    ..e. PTSD, phobias, addiction and depression) and debilitating conditions of memory loss such as those occurring in aging and Alzheimer's Disease. ..
  8. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2006
    ..An understanding of the molecular changes underlying memory formation may indicate new strategies for the treatment of memory disorders. ..
  9. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2005
    ..An understanding of the molecular changes underlying memory formation may indicate new strategies for the treatment of memory disorders. ..
  10. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2004
    ..An understanding of the molecular changes underlying memory formation may indicate new strategies for the treatment of memory disorders. ..
  11. Gene Expression in Long-term Memory
    Cristina Alberini; Fiscal Year: 2003
    ..An understanding of the molecular changes underlying memory formation may indicate new strategies for the treatment of memory disorders. ..
  12. Gene Expression in Long-term Memory
    Cristina M Alberini; Fiscal Year: 2010
    ....